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  1. Article ; Online: Commentary on Anatomical and histomorphometric observations on the transfer of the anterior interosseous nerve to the deep branch of the ulnar nerve. T. L. Schenck, J. Stewart, S. Lin, M. Aichler, H.-G. Machens and R. E. Giunta. J Hand Surg Eur. 2015, 40: 591-6.

    Hart, A

    The Journal of hand surgery, European volume

    2015  Volume 40, Issue 6, Page(s) 597

    MeSH term(s) Forearm/innervation ; Humans ; Nerve Transfer ; Ulnar Nerve/pathology ; Ulnar Nerve/surgery
    Language English
    Publishing date 2015-07
    Publishing country England
    Document type Comment ; Journal Article
    ZDB-ID 2272801-6
    ISSN 2043-6289 ; 1753-1934
    ISSN (online) 2043-6289
    ISSN 1753-1934
    DOI 10.1177/1753193415575981
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book: G.R. Derzhavin

    Hart, Pierre R

    a poet's progress

    1978  

    Author's details Pierre Hart
    Language English
    Size 164 S
    Publisher Slavica Publ
    Publishing place Columbus, O
    Document type Book
    ISBN 0893570540 ; 9780893570545
    Database Former special subject collection: coastal and deep sea fishing

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  3. Article ; Online: Striatal dopamine release tracks the relationship between actions and their consequences.

    Hart, G / Burton, T J / Nolan, C R / Balleine, B W

    Cell reports

    2024  Volume 43, Issue 3, Page(s) 113828

    Abstract: The acquisition and performance of goal-directed actions has long been argued to depend on the integration of glutamatergic inputs to the posterior dorsomedial striatum (pDMS) under the modulatory influence of dopamine. Nevertheless, relatively little is ...

    Abstract The acquisition and performance of goal-directed actions has long been argued to depend on the integration of glutamatergic inputs to the posterior dorsomedial striatum (pDMS) under the modulatory influence of dopamine. Nevertheless, relatively little is known about the dynamics of striatal dopamine during goal-directed actions. To investigate this, we chronically recorded dopamine release in the pDMS as rats acquired two actions for distinct outcomes as these action-outcome associations were incremented and then subsequently degraded or reversed. We found that bilateral dopamine release scaled with action value, whereas the lateralized dopamine signal, i.e., the difference in dopamine release ipsilaterally and contralaterally to the direction of the goal-directed action, reflected the strength of the action-outcome association independently of changes in movement. Our results establish, therefore, that striatal dopamine activity during goal-directed action reflects both bilateral moment-to-moment changes in action value and the long-term action-outcome association.
    MeSH term(s) Rats ; Animals ; Dopamine/metabolism ; Conditioning, Operant ; Corpus Striatum/metabolism ; Neostriatum/metabolism
    Chemical Substances Dopamine (VTD58H1Z2X)
    Language English
    Publishing date 2024-02-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2649101-1
    ISSN 2211-1247 ; 2211-1247
    ISSN (online) 2211-1247
    ISSN 2211-1247
    DOI 10.1016/j.celrep.2024.113828
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Deep Brain Stimulation Improves Symptoms of Spasmodic Dysphonia Through Targeting of Thalamic Sensorimotor Connectivity.

    Hart, Michael G / Polyhronopoulos, Nancy / Sandhu, Mandeep K / Honey, Christopher R

    Neurosurgery

    2024  

    Abstract: Background and objectives: Spasmodic dysphonia is a dystonia of the vocal chords producing difficulty with speech. Current hypotheses are that this is a condition of dysregulated thalamic sensory motor integration. A recent randomized controlled trial ... ...

    Abstract Background and objectives: Spasmodic dysphonia is a dystonia of the vocal chords producing difficulty with speech. Current hypotheses are that this is a condition of dysregulated thalamic sensory motor integration. A recent randomized controlled trial of thalamic deep brain stimulation (DBS) demonstrated its safety and efficacy. Our objective was to determine whether the outcome could be predicted by stimulation of thalamic sensorimotor areas and adjacent white matter connectivity as assessed by diffusion tractography.
    Methods: A cohort of 6 participants undergoing thalamic DBS for adductor spasmodic dysphonia was studied. Electrodes were localized with the Lead-DBS toolbox. Group-based analyses were performed with atlases, coordinates, and using voxel-based symptom mapping. Diffusion tensor imaging (3 T, 64 directions, 2-mm isotropic) was used to perform individual probabilistic tractography (cerebellothalamic tract and pallidothalamic tract) and segmentation of the thalamus. Monopolar review was performed at 0.5 V and binarised as effective or ineffective.
    Results: Effective contacts stimulated more of thalamic sensorimotor areas than ineffective contacts (P < .05, false discovery rate corrected). This effect was consistent across analytical and statistical techniques. Group-level and tractography analyses did not identify a specific "sweet spot" suggesting the benefit of DBS is derived from modulating individual thalamic sensorimotor areas. Stimulations at 1 year involved predicted thalamic sensorimotor regions with additional cerebellothalamic tract involvement.
    Conclusion: Stimulation of thalamic sensorimotor areas was associated with improvement in symptoms of spasmodic dysphonia. These data are consistent with DBS acting on pathophysiologically dysregulated thalamic sensorimotor integration in spasmodic dysphonia.
    Language English
    Publishing date 2024-01-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 135446-2
    ISSN 1524-4040 ; 0148-396X
    ISSN (online) 1524-4040
    ISSN 0148-396X
    DOI 10.1227/neu.0000000000002836
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1424: Show issues Location:
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    Zs.MO 539: Show issues

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  5. Article ; Online: Spherical shock waveform reconstruction by heterodyne interferometry.

    Hart, Carl R / Lyons, Gregory W / White, Michael J

    The Journal of the Acoustical Society of America

    2024  Volume 155, Issue 1, Page(s) 769–780

    Abstract: ... interferometer, e.g., a laser Doppler vibrometer, the reconstructed field is the fluctuating refractive index ...

    Abstract The indirect measurement of shock waveforms by acousto-optic sensing requires a method to reconstruct the field from the projected data. Under the assumption of spherical symmetry, one approach is to reconstruct the field by the Abel inversion integral transform. When the acousto-optic sensing modality measures the change in optical phase difference time derivative, as for a heterodyne Mach-Zehnder interferometer, e.g., a laser Doppler vibrometer, the reconstructed field is the fluctuating refractive index time derivative. A technique is derived that reconstructs the fluctuating index directly by assuming plane wave propagation local to a probe beam. With synthetic data, this approach is compared to the Abel inversion integral transform and then applied to experimental data of laser-induced shockwaves. Time waveforms are reconstructed with greater accuracy except for the tail of the waveform that maps spatially to positions near a virtual origin. Furthermore, direct reconstruction of the fluctuating index field eliminates the required time integration and results in more accurate shock waveform peak values, rise times, and positive phase duration.
    Language English
    Publishing date 2024-01-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 219231-7
    ISSN 1520-8524 ; 0001-4966
    ISSN (online) 1520-8524
    ISSN 0001-4966
    DOI 10.1121/10.0024520
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Socioeconomic disparities and neuroplasticity: Moving toward adaptation, intersectionality, and inclusion.

    Noble, Kimberly G / Hart, Emma R / Sperber, Jessica F

    The American psychologist

    2022  Volume 76, Issue 9, Page(s) 1486–1495

    Abstract: Childhood socioeconomic status (SES) has far-reaching linkages with children's cognitive and socioemotional development, academic achievement, health, and brain structure and function. Rather than focusing on understandings about the neuroscience of ... ...

    Abstract Childhood socioeconomic status (SES) has far-reaching linkages with children's cognitive and socioemotional development, academic achievement, health, and brain structure and function. Rather than focusing on understandings about the neuroscience of socioeconomic inequality that have recently been reviewed elsewhere, the present article reviews several new directions in the field, beginning first with a consideration of the deficit versus adaptation framework. Although scientists largely agree that socioeconomic disparities in brain development are experience-dependent phenomena rooted in neuroplasticity, historically, such differences have been framed as deficits, which may benefit from intervention. However, emerging research suggests that some developmental differences among children experiencing adversity may alternatively be considered context-appropriate adaptations to the individual's environment. We next discuss how socioeconomic circumstances are inextricably intertwined with race, and consider how measurement of racism and discrimination must be part of a full understanding of the neuroscience of socioeconomic inequality. We argue that scientists must consciously recruit racially and socioeconomically diverse samples-and include measures of SES, race, and discrimination in analyses-to promote a more complete understanding of the neuroplasticity specifically, and psychological science more broadly. We discuss the extent to which researcher and editor positionality have contributed to these problems historically, and conclude by considering paths forward. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
    MeSH term(s) Child ; Educational Status ; Humans ; Intersectional Framework ; Neuronal Plasticity ; Racism ; Social Class ; Socioeconomic Factors
    Language English
    Publishing date 2022-03-09
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 209464-2
    ISSN 1935-990X ; 0003-066X
    ISSN (online) 1935-990X
    ISSN 0003-066X
    DOI 10.1037/amp0000934
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 997: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  7. Article ; Online: Klimaatadaptatie

    't Hart, Paul / Pot, W.D. / Biesbroek, G.R.

    Maatschappelijke bestuurskunde ; ISBN: 9789462363670

    hoe leggen we onze oogkleppen af?

    2023  

    Keywords Life Science
    Language English
    Publisher Boom
    Publishing country nl
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Transmembrane protein 184B (TMEM184B) promotes expression of synaptic gene networks in the mouse hippocampus.

    Wright, Elizabeth B / Larsen, Erik G / Coloma-Roessle, Cecilia M / Hart, Hannah R / Bhattacharya, Martha R C

    BMC genomics

    2023  Volume 24, Issue 1, Page(s) 559

    Abstract: In Alzheimer's Disease (AD) and other dementias, hippocampal synaptic dysfunction and loss contribute to the progression of memory impairment. Recent analysis of human AD transcriptomes has provided a list of gene candidates that may serve as drivers of ... ...

    Abstract In Alzheimer's Disease (AD) and other dementias, hippocampal synaptic dysfunction and loss contribute to the progression of memory impairment. Recent analysis of human AD transcriptomes has provided a list of gene candidates that may serve as drivers of disease. One such candidate is the membrane protein TMEM184B. To evaluate whether TMEM184B contributes to neurological impairment, we asked whether loss of TMEM184B in mice causes gene expression or behavior alterations, focusing on the hippocampus. Because one major risk factor for AD is age, we compared young adult (5-month-old) and aged (15-month-old) wild type and Tmem184b-mutant mice to assess the dual contributions of age and genotype. TMEM184B loss altered expression of pre- and post-synaptic transcripts by 5 months and continued through 15 months, specifically affecting genes involved in synapse assembly and neural development. Wnt-activated enhancer elements were enriched among differentially expressed genes, suggesting an intersection with this pathway. Few differences existed between young adult and aged mutants, suggesting that transcriptional effects of TMEM184B loss are relatively constant. To understand how TMEM184B disruption may impact behaviors, we evaluated memory using the novel object recognition test and anxiety using the elevated plus maze. Young adult Tmem184b-mutant mice show normal object discrimination, suggesting a lack of memory impairment at this age. However, mutant mice showed decreased anxiety, a phenotype seen in some neurodevelopmental disorders. Taken together, our data suggest that TMEM184B is required for proper synaptic gene expression and anxiety-related behavior and is more likely to be linked to neurodevelopmental disorders than to dementia.
    MeSH term(s) Humans ; Young Adult ; Animals ; Mice ; Infant ; Gene Regulatory Networks ; Alzheimer Disease ; Genotype ; Hippocampus ; Membrane Proteins/genetics
    Chemical Substances Membrane Proteins
    Language English
    Publishing date 2023-09-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041499-7
    ISSN 1471-2164 ; 1471-2164
    ISSN (online) 1471-2164
    ISSN 1471-2164
    DOI 10.1186/s12864-023-09676-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: ArcTiCA: Arctic tidal constituents atlas.

    Hart-Davis, M G / Howard, S L / Ray, R D / Andersen, O B / Padman, L / Nilsen, F / Dettmering, D

    Scientific data

    2024  Volume 11, Issue 1, Page(s) 167

    Abstract: ... tidal variability in the Arctic Ocean; e.g., the global TICON-3 database contains only 111 sites above ...

    Abstract Tides in the Arctic Ocean affect ocean circulation and mixing, and sea ice dynamics and thermodynamics. However, there is a limited network of available in situ tidal coefficient data for understanding tidal variability in the Arctic Ocean; e.g., the global TICON-3 database contains only 111 sites above 60°N and 21 above 70°N. At the same time, the presence of sea ice and latitude limits of satellite altimetry complicate altimetry-based retrievals of Arctic tidal coefficients. This leads to a reliance on ocean tide models whose accuracy depend on having sufficient in situ data for validation and assimilation. Here, we present a comprehensive new dataset of tidal constituents in the Arctic region, combining analyses of in situ measurements from tide gauges, ocean bottom pressure sensors and GNSS interferometric reflectometry. The new dataset contains 914 measurement sites above 60°N and 399 above 70°N, with each site being quality-assessed and expert guidance provided to help maximise the usage of the dataset. We also compare the dataset to recent tide models.
    Language English
    Publishing date 2024-02-03
    Publishing country England
    Document type Dataset ; Journal Article
    ZDB-ID 2775191-0
    ISSN 2052-4463 ; 2052-4463
    ISSN (online) 2052-4463
    ISSN 2052-4463
    DOI 10.1038/s41597-024-03012-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Increased variance in second electrode accuracy during deep brain stimulation and its relationship to pneumocephalus, brain shift, and clinical outcomes: A retrospective cohort study.

    Hart, M G / Posa, M / Buttery, P C / Morris, R C

    Brain & spine

    2022  Volume 2, Page(s) 100893

    Abstract: Overall electrode accuracy was 0.22+/-0.4 ​mm with only 3 (4%) electrodes out with 2 ​mm from the intended target.•Accuracy was significantly worse in the GPi versus the STN and on the second side implanted.•Inaccuracy occurred in the X (lateral) plane ... ...

    Abstract •Overall electrode accuracy was 0.22+/-0.4 ​mm with only 3 (4%) electrodes out with 2 ​mm from the intended target.•Accuracy was significantly worse in the GPi versus the STN and on the second side implanted.•Inaccuracy occurred in the X (lateral) plane but was not related to pneumocephalus or brain shift.
    Language English
    Publishing date 2022-05-21
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2772-5294
    ISSN (online) 2772-5294
    DOI 10.1016/j.bas.2022.100893
    Database MEDical Literature Analysis and Retrieval System OnLINE

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