LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 82075

Search options

  1. Article ; Online: Analysis of the Dong bao Ye as sacred landscape and its Putative therapeutic mechanisms.

    Yang, Shiqi / Liu, Juanjuan / Winterbottom, Daniel

    Health & place

    2023  Volume 83, Page(s) 103102

    Abstract: ... the sacred bao ye landscape of the Dong people of China as the research subject. By adopting the case study ...

    Abstract Humans have innately established close and profound ties with the, and through these relationships shaped many kinds of landscapes. Among these are sacred landscapes, which have drawn the attention of researchers due to their cultural significance. In the field of health geography, large-sized sacred regional landscapes are now the focus of studies for their therapeutic properties. However, few scholars have focused on small sacred landscape systems at the community level (constructed by local communities) or the physical and psycological health benefits that these landscapes offer to the local residents. These small-sized and widespread, but often hidden, sacred landscapes are closely tied to people's daily lives and work. They have evolved and grown over millennia to become critical sociocultural phenomena. This study takes the sacred bao ye landscape of the Dong people of China as the research subject. By adopting the case study approach, field research, semi-structured interviews, and textual analysis, it summarizes the types, geographical distribution, rituals and processes of bao ye as a sacred landscape of the Huanggang village in Guizhou Province, and concludes with an analysis of motivation and health benefits to the bao ye worship. In this paper we argue that bao ye is a sacred landscape system focusing on the healthy development of children, and constitutes a local belief developed in an isolated environment lacking medical resources, which remains in practice. The sacred landscape of bao ye offers a therapeutic environment, providing children with increased opportunities to engage with and build deep connections to nature. Thruogh this process children may develop a bond with nature that inspires them to protect nature on their own accord. We argue that bao ye offers an important case study for understanding the landscape-people-healing interactivity at the community level.
    MeSH term(s) Child ; Humans ; China ; Geography ; Health Status ; Motivation
    Language English
    Publishing date 2023-08-29
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1262540-1
    ISSN 1873-2054 ; 1353-8292
    ISSN (online) 1873-2054
    ISSN 1353-8292
    DOI 10.1016/j.healthplace.2023.103102
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Comprehensive analyses of genetic diversities and population structure of the Guizhou Dong group based on 44 Y-markers.

    Zhang, Hongling / Huang, Xiaolan / Jin, Xiaoye / Ren, Zheng / Wang, Qiyan / Yang, Meiqing / Xu, Ronglan / Yuan, Xiang / Yang, Daiquan / Liu, Hongyan / Shen, Wanyi / Zhang, Huiying / Que, Yangjie / Huang, Jiang

    PeerJ

    2023  Volume 11, Page(s) e16183

    Abstract: ... the genetic distribution of Y-STRs in the Guizhou Dong population, provide reference data for forensic ... application, and explore the phylogenetic relationships between the Guizhou Dong population and ... other comparison populations.: Methods: Based on the allele profile of 44 Y-markers in the Guizhou Dong group ...

    Abstract Background: The non-recombining region of the human Y chromosome (NRY) is a strictly paternally inherited genetic marker and the best material to trace the paternal lineages of populations. Y chromosomal short tandem repeat (Y-STR) is characterized by high polymorphism and paternal inheritance pattern, so it has been widely used in forensic medicine and population genetic research. This study aims to understand the genetic distribution of Y-STRs in the Guizhou Dong population, provide reference data for forensic application, and explore the phylogenetic relationships between the Guizhou Dong population and other comparison populations.
    Methods: Based on the allele profile of 44 Y-markers in the Guizhou Dong group, we estimate their allele frequencies and haplotype frequencies. In addition, we also compare the forensic application efficiency of different Y-STR sets in the Guizhou Dong group. Finally, genetic relationships among Guizhou Dong and other reference populations are dissected by the multi-dimensional scaling and the phylogenetic tree.
    Results: A total of 393 alleles are observed in 312 Guizhou Dong individuals for these Y-markers, with allele frequencies ranging from 0.0032 to 0.9679. The haplotype diversity and discriminatory capacity for these Y-markers in the Guizhou Dong population are 0.99984 and 0.97440, respectively. The population genetic analyses of the Guizhou Dong group and other reference populations show that the Guizhou Dong group has the closest genetic relationship with the Hunan Dong population, and followed by the Guizhou Tujia population.
    Conclusions: In conclusion, these 44 Y-markers can be used as an effective tool for male differentiation in the Guizhou Dong group. The haplotype data in this study not only enrich the Y-STR data of different ethnic groups in China, but also have important significance for population genetics and forensic research.
    MeSH term(s) Humans ; Phylogeny ; Gene Frequency ; Genetics, Population ; Polymorphism, Genetic/genetics ; Ethnicity/genetics
    Language English
    Publishing date 2023-09-25
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2703241-3
    ISSN 2167-8359 ; 2167-8359
    ISSN (online) 2167-8359
    ISSN 2167-8359
    DOI 10.7717/peerj.16183
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Amino accelerators and antioxidants in sediments from the Dong Nai River System, Vietnam: Distribution and influential factors.

    Jin, Ruihe / Li, Yue / Saito, Yoshiki / Wang, Zhanghua / Oanh Ta, Thi Kim / Nguyen, Van Lap / Yang, Jing / Liu, Min / Wu, Yan

    Environmental research

    2023  Volume 227, Page(s) 115712

    Abstract: ... Os and five AAO transformation products (AAOTPs) in seventy-seven sediments from the Dong Nai ...

    Abstract Amino accelerators and antioxidants (AAL/Os) have become a suite of contaminants of emerging concern recently due to the accumulating evidence for their environmental occurrence and associated toxic potential. Nevertheless, data on sedimentary deposition of AAL/Os has remained scarce, particularly for regions beyond the North America. In the present study, we elucidated spatial distribution of fifteen AAL/Os and five AAO transformation products (AAOTPs) in seventy-seven sediments from the Dong Nai River System (DNRS), Vietnam. Total concentrations of AAL/Os (∑AAL/Os) ranged from 0.377 to 51.4 ng/g (median: 5.01 ng/g). 1,3-Diphenylguanidine and 4,4'-bis(1,1-dimethylbenzyl) diphenylamine were the two most prevalent congeners, both with detection frequencies >80%. Additionally, AAOTPs were quantifiable in 79% of the DNRS sediments with a median ∑AAOTPs at 2.19 ng/g, dominated by N, N'-diphenylbenzidine and 2-nitrodiphenylamine. Higher sediment-associated levels of AAL/Os and AAOTPs were spotted in downstream and the primary tributary of the DNRS compared to the upstream, implying their cumulative sedimentation towards the estuarine region. The distribution patterns of AAL/Os and AAOTPs across individual transects also demonstrated the influence of human activities (e.g., urbanization and agriculture), hydrodynamics, and decontamination by mangrove reserves. Meanwhile, characteristics of sediments, i.e., total organic carbon (TOC) content and grain sizes, exhibited significant correlations with the burdens of these compounds, indicating their preferential partitioning into the fine and TOC-rich matter. This research sheds light on environmental behavior of AAL/Os and AAOTPs beneath Asian aquatic system, and highlights the need for further evaluation of their impacts on the wildlife and public health.
    MeSH term(s) Humans ; Antioxidants ; Water Pollutants, Chemical/analysis ; Vietnam ; Rivers ; Agriculture ; Geologic Sediments ; Environmental Monitoring ; China
    Chemical Substances Antioxidants ; Water Pollutants, Chemical
    Language English
    Publishing date 2023-03-16
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2023.115712
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: The Tian-Men-Dong decoction suppresses the tumour-infiltrating G-MDSCs via IL-1β-mediated signalling in lung cancer.

    Su, Lin / Zhang, Fei / Liu, Ming-Xi / Li, Hong / Li, Qiang / Zhu, Yang-Zhuangzhuang / Hou, Yi-Fei / Chen, Xiao / Wang, Xiao-Yu / Qian, Chun-Mei / Yao, Chao / Wang, Li-Xin / Jiao, Xiao-Ning / Zhu, Xian-Dan / Xu, Zi-Hang / Zou, Chun-Pu

    Journal of ethnopharmacology

    2023  Volume 313, Page(s) 116491

    Abstract: Ethnopharmacological relevance: The traditional Chinese medicine (TCM) Tian-Men-Dong decoction (TD ...

    Abstract Ethnopharmacological relevance: The traditional Chinese medicine (TCM) Tian-Men-Dong decoction (TD) has been able to effectively treat lung cancer in China for thousands of years. TD improves the quality of life in lung cancer patients by promoting nourishment of yin and reducing dryness, clearing the lung and removing toxins. Pharmacological studies show that TD contains active antitumour ingredients, but its underlying mechanism remains unknown.
    Aim of the study: This study aims at exploring potential mechanisms of TD in the treatment of lung cancer by regulating granulocytic-myeloid-derived suppressor cells (G-MDSCs).
    Materials and methods: An orthotopic lung cancer mouse model was generated by intrapulmonary injection with LLC-luciferase cells in immunocompetent C57BL/6 mice or immunodeficient nude mice. TD/saline was orally administered once to the model mice daily for 4 weeks. Live imaging was conducted to monitor tumour growth. Immune profiles were detected by flow cytometry. H&E and ELISA were applied to test the cytotoxicity of the TD treatment. RT-qPCR and western blotting were performed to detect apoptosis-related proteins in G-MDSCs. A neutralizing antibody (anti-Ly6G) was utilized to exhaust the G-MDSCs via intraperitoneal injection. G-MDSCs were adoptively transferred from wild-type tumour-bearing mice. Immunofluorescence, TUNEL and Annexin V/PI staining were conducted to analyse apoptosis-related markers. A coculture assay of purified MDSCs and T cells labelled with CFSE was performed to test the immunosuppressive activity of MDSCs. The presence of TD/IL-1β/TD + IL-1β in purified G-MDSCs cocultured with the LLC system was used for ex vivo experiments to detect IL-1β-mediated apoptosis of G-MDSCs.
    Results: TD prolonged the survival of immune competent C57BL/6 mice in an orthotopic lung cancer model, but did not have the same effect in immunodeficient nude mice, indicating that its antitumour properties of TD are exerted by regulating immunity. TD induced G-MDSC apoptosis via the IL-1β-mediated NF-κB signalling cascade leading to effectively weaken the immunosuppressive activity of G-MDSCs and promote CD8
    Conclusion: This study reveals for the first time that TD, a classic TCM prescription, is able to regulate G-MDSC activity and trigger its apoptosis via the IL-1β-mediated NF-κB signalling pathway, reshaping the tumour microenvironment and demonstrating antitumour effects. These findings provide a scientific foundation the clinical treatment of lung cancer with TD.
    MeSH term(s) Mice ; Animals ; Myeloid-Derived Suppressor Cells ; Mice, Nude ; NF-kappa B/metabolism ; Quality of Life ; Mice, Inbred C57BL ; Lung Neoplasms/metabolism ; Immunosuppressive Agents/pharmacology ; Tumor Microenvironment
    Chemical Substances NF-kappa B ; Immunosuppressive Agents
    Language English
    Publishing date 2023-04-16
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 134511-4
    ISSN 1872-7573 ; 0378-8741
    ISSN (online) 1872-7573
    ISSN 0378-8741
    DOI 10.1016/j.jep.2023.116491
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: X-chromosomal STRs for genetic composition analysis of Guizhou Dong group and its phylogenetic relationships with other reference populations.

    Yang, Meiqing / Jin, Xiaoye / Ren, Zheng / Wang, Qiyan / Zhang, Hongling / Zhang, Han / Chen, Jing / Ji, Jingyan / Liu, Yubo / Huang, Jiang

    Annals of human biology

    2022  Volume 48, Issue 7-8, Page(s) 621–626

    Abstract: ... chromosome play crucial roles in forensic research and human evolution. Dong group, one of 55 minority groups ... short tandem repeats (STRs) and autosomal insertion/deletion polymorphism (InDels) in Dong groups have been reported ... there is little research about X-STRs in the Dong group.: Aim: Purposes of this study are ...

    Abstract Background: X-chromosomes show a specific genetic mode, which makes genetic markers on the X-chromosome play crucial roles in forensic research and human evolution. Dong group, one of 55 minority groups in China, live in Guizhou, Guangxi, and Hunan provinces. Even though some genetic data of Y chromosomal short tandem repeats (STRs) and autosomal insertion/deletion polymorphism (InDels) in Dong groups have been reported, there is little research about X-STRs in the Dong group.
    Aim: Purposes of this study are to investigate allelic distributions and forensic statistical parameters of 19 X-STRs in the Guizhou Dong group, and explore the genetic composition of the Guizhou Dong group and its phylogenetic relationships with other reference populations.
    Subjects and methods: Five hundred and seven Dongs (272 males and 235 females) living in Guizhou province were typed using the AGCU X19 STR kit. Allelic frequencies and forensic parameters of 19 X-STRs in the Guizhou Dong group were calculated. Population genetic analyses of Guizhou Dong and another 17 reference populations were conducted using
    Results: A total of 230 alleles of 19 X-STRs were identified in all Dongs. The frequencies of 19 loci ranged from 0.0013 to 0.6838. The values for cumulative power of discrimination in males (PDM), cumulative power of discrimination in females (PDF), and four different kinds of mean exclusion chance (MEC_Kruger, MEC_Kishida, MEC_Desmarais, and MEC_Desmarais_du) for the 19 X-STRs in all individuals were 0.999999999999761, 0.9999999999999999999993951, 0.999999964841617, 0.999999999997261, 0.999999999997297, and 0.999999993623172, respectively. Besides, genetic polymorphisms of seven linkage clusters ranged from 0.9381 to 0.9963. In addition, these seven groups showed high polymorphism information content (PIC), PDM, PDF, MEC_Kruger, MEC_Kishida, MEC_Desmarais, and MEC_Desmarais_duo. Population genetic analyses of Guizhou Dong and another 17 reference populations showed that the Guizhou Dong group had close genetic relationships with surrounding Tai-Kadai-speaking, Hmong-Mien-speaking, and Han groups.
    Conclusion: Nineteen X-STRs displayed high genetic diversities and could be employed for forensic personal identification and paternity analysis in the Guizhou Dong group. Close genetic affinities between Guizhou Dong and surrounding populations were observed based on the 19 X-STRs in 17 reference populations.
    MeSH term(s) China ; Ethnicity ; Female ; Gene Frequency ; Genetics, Population ; Humans ; Male ; Microsatellite Repeats ; Phylogeny
    Language English
    Publishing date 2022-02-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 186656-4
    ISSN 1464-5033 ; 0301-4460
    ISSN (online) 1464-5033
    ISSN 0301-4460
    DOI 10.1080/03014460.2021.2008001
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Genetic analysis of the mitochondrial DNA control region in Tai-Kadai-speaking Dong population in southwest China.

    Ren, Zheng / Feng, Yuhang / Zhang, Hongling / Wang, Qiyan / Yang, Meiqing / Liu, Yubo / Le, Cuiyun / Wang, Jie / Huang, Jiang

    Annals of human biology

    2022  Volume 49, Issue 7-8, Page(s) 354–360

    Abstract: Background: Dong people in Southwest China are officially recognised as an ethnic group, but there ... in a typical Dong population, and to provide help for the construction of a forensic mitochondrial DNA analysis ... region were analysed in 200 individuals of Dong in Guizhou. The haplotype frequencies, haplogroup ...

    Abstract Background: Dong people in Southwest China are officially recognised as an ethnic group, but there has been a lack of population genetic research on this group, especially based on mitochondrial DNA data.
    Aim: To study the sequences and haplogroups of the mitochondrial DNA control region in a typical Dong population, and to provide help for the construction of a forensic mitochondrial DNA analysis reference database in East Asia.
    Subjects and methods: The sequences of the mitochondrial DNA control region were analysed in 200 individuals of Dong in Guizhou. The haplotype frequencies, haplogroup distribution and paired Fst values of Guizhou Dong and 51 other populations in the world were calculated and explained to explore the genetic polymorphism and population relationships.
    Results: A total of 180 haplotypes were detected, with frequencies of 0.005-0.02. All haplotypes were assigned to 97 different haplogroups. The haplotype diversity and random matching probability were 0.998643 and 0.00635, respectively. The paired Fst values and correlation
    Conclusions: Our study was based on the matrilineal genetic structure of Guizhou Dong to study mitochondrial DNA, which was helpful to promote the establishment of the forensic DNA reference database in East Asia and provide reference for anthropological research.
    MeSH term(s) Humans ; DNA, Mitochondrial/genetics ; Polymorphism, Genetic ; Ethnicity/genetics ; Haplotypes ; China
    Chemical Substances DNA, Mitochondrial
    Language English
    Publishing date 2022-11-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 186656-4
    ISSN 1464-5033 ; 0301-4460
    ISSN (online) 1464-5033
    ISSN 0301-4460
    DOI 10.1080/03014460.2022.2131334
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Exposure to multiple metals and diabetes mellitus risk in dong ethnicity in China: from the China multi-ethnic cohort study.

    Yang, Qianyuan / Liu, Yalan / Liu, Leilei / Zhang, Linyuan / Lei, Juan / Wang, Qiaorong / Hong, Feng

    Environmental geochemistry and health

    2022  Volume 45, Issue 5, Page(s) 2435–2445

    Abstract: ... of metals with diabetes among the Dong ethnicity in China remains poorly understood. The current study aimed ... among 4479 Dong ethnic participants aged 30-79 years from the China Multi-Ethnic Cohort (CMEC) study. Based ...

    Abstract Metals play an important role in the development of diabetes mellitus (DM). The association of metals with diabetes among the Dong ethnicity in China remains poorly understood. The current study aimed to evaluate the association of single metal exposure and multi-metal co-exposure with DM risk. Urinary concentrations of arsenic, cadmium, chromium, copper, iron, lead, manganese, mercury, molybdenum, nickel, strontium, vanadium, and zinc were measured using inductively coupled plasma-mass spectrometry (ICP-MS) among 4479 Dong ethnic participants aged 30-79 years from the China Multi-Ethnic Cohort (CMEC) study. Based on tertiles, the metal exposure can be divided into three groups: low, middle, and high exposure. Multivariate logistic regression models and principal component analysis were performed to determine exposure to single-metal and multi-metal co-exposure in relation to DM. A decrease in risk of DM was associated with iron (OR = 0.78, 95% CI: 0.61-1.00 and 0.68, 0.53-0.88 for the middle and high vs. low) and strontium (OR = 0.87, 95% CI: 0.69-1.12 and 0.67, 0.51-0.86 for the middle and high vs. low), respectively. A principal component 3 (PC3) characterized by iron and strontium showed an inverse association with DM. A principal component 4 (PC4) characterized by manganese and lead positively associated with DM. Exposure to high concentrations of urinary iron and strontium may reduce the risk of diabetes mellitus. This study revealed an increase in the risk of diabetes mellitus by co-exposure to high concentrations of urinary manganese and lead.
    MeSH term(s) Humans ; Cohort Studies ; Manganese/toxicity ; Ethnicity ; Iron ; Strontium ; Diabetes Mellitus/epidemiology ; Arsenic/toxicity ; Vanadium ; China/epidemiology
    Chemical Substances Manganese (42Z2K6ZL8P) ; Iron (E1UOL152H7) ; Strontium (YZS2RPE8LE) ; Arsenic (N712M78A8G) ; Vanadium (00J9J9XKDE)
    Language English
    Publishing date 2022-08-20
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 52039-1
    ISSN 1573-2983 ; 0142-7245 ; 0269-4042
    ISSN (online) 1573-2983
    ISSN 0142-7245 ; 0269-4042
    DOI 10.1007/s10653-022-01366-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Dong Leshan

    kun YANG

    Canadian Social Science, Vol 11, Iss 3, Pp 162-

    A Thinker-Translator

    2015  Volume 165

    Abstract: The late Mr. Dong Leshan is a well-renowned translator in China. Most of his translated works, like ... of America 1932-1972, and 1984 enjoys a great reputation. This paper reviews and analyzes Dong Leshan’s ...

    Abstract The late Mr. Dong Leshan is a well-renowned translator in China. Most of his translated works, like The Rise and Fall of the Third Reich, Red Star over China, The Glory and the Dream: A Narrative History of America 1932-1972, and 1984 enjoys a great reputation. This paper reviews and analyzes Dong Leshan’s translation achievements, characteristics and ideas, maintaining that the above mentioned aspects of him make him a thinker-translator.
    Keywords Dong Leshan ; Translator ; Characteristics ; Social Sciences ; H ; Social sciences (General) ; H1-99
    Publishing date 2015-03-01T00:00:00Z
    Publisher Canadian Research & Development Center of Sciences and Cultures
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  9. Article ; Online: Evaluation of anthropometric indices as a predictor of diabetes in Dong and Miao ethnicities in China

    Qianyuan Yang / Yalan Liu / Zhaofeng Jin / Leilei Liu / Zhiping Yuan / Degan Xu / Feng Hong

    PLoS ONE, Vol 17, Iss

    A cross-sectional analysis of China Multi-Ethnic Cohort Study

    2022  Volume 3

    Abstract: ... for predicting diabetes. Method In total, 11,035 Dong and Miao ethnic participants (age: 30–79 years ... Among Chinese Dong men and women and Miao men, WHR had the largest AUC (0.654/0.719/0.651). Among Miao women ... VAI had the largest AUC(0.701). The best cut-off values of WHR for Dong men and women and Miao men ...

    Abstract Background Although it is known that obesity is inseparable from diabetes, many anthropometric indices are used for determining obesity. At the same time, research on the predictive indices of diabetes in Chinese minority populations is lacking. Therefore, this study determines the relationship between different anthropometric indices and diabetes, and identifies the best index and best cut-off values for predicting diabetes. Method In total, 11,035 Dong and Miao ethnic participants (age: 30–79 years) from the China Multi-Ethnic Cohort study were included. The logistic regression model was used to examine the relationship between the different anthropometric indices and diabetes risk. The receiver operating characteristic curve and the area under the curve (AUC) were used to identify the best predictor of diabetes. Results In multivariate adjusted logistic regression models, body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), a body shape index (ABSI), body roundness index (BRI), and visceral adiposity index (VAI) were positively correlated with diabetes risk. Among Chinese Dong men and women and Miao men, WHR had the largest AUC (0.654/0.719/0.651). Among Miao women, VAI had the largest AUC(0.701). The best cut-off values of WHR for Dong men and women and Miao men were 0.94, 0.92, and 0.91, respectively. The best cut-off value of VAI for Miao women was 2.20. Conclusion Obesity indicators better predict diabetes in women than men. WHR may be the best predictor of diabetes risk in both sex of Dong ethnicity and Miao men, and VAI may be the best predictor of diabetes risk in Miao women.
    Keywords Medicine ; R ; Science ; Q
    Subject code 571
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  10. Article ; Online: Evaluation of anthropometric indices as a predictor of diabetes in Dong and Miao ethnicities in China

    Qianyuan Yang / Yalan Liu / Zhaofeng Jin / Leilei Liu / Zhiping Yuan / Degan Xu / Feng Hong

    PLoS ONE, Vol 17, Iss 3, p e

    A cross-sectional analysis of China Multi-Ethnic Cohort Study.

    2022  Volume 0265228

    Abstract: ... for predicting diabetes. Method In total, 11,035 Dong and Miao ethnic participants (age: 30-79 years ... Among Chinese Dong men and women and Miao men, WHR had the largest AUC (0.654/0.719/0.651). Among Miao women ... VAI had the largest AUC(0.701). The best cut-off values of WHR for Dong men and women and Miao men ...

    Abstract Background Although it is known that obesity is inseparable from diabetes, many anthropometric indices are used for determining obesity. At the same time, research on the predictive indices of diabetes in Chinese minority populations is lacking. Therefore, this study determines the relationship between different anthropometric indices and diabetes, and identifies the best index and best cut-off values for predicting diabetes. Method In total, 11,035 Dong and Miao ethnic participants (age: 30-79 years) from the China Multi-Ethnic Cohort study were included. The logistic regression model was used to examine the relationship between the different anthropometric indices and diabetes risk. The receiver operating characteristic curve and the area under the curve (AUC) were used to identify the best predictor of diabetes. Results In multivariate adjusted logistic regression models, body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), a body shape index (ABSI), body roundness index (BRI), and visceral adiposity index (VAI) were positively correlated with diabetes risk. Among Chinese Dong men and women and Miao men, WHR had the largest AUC (0.654/0.719/0.651). Among Miao women, VAI had the largest AUC(0.701). The best cut-off values of WHR for Dong men and women and Miao men were 0.94, 0.92, and 0.91, respectively. The best cut-off value of VAI for Miao women was 2.20. Conclusion Obesity indicators better predict diabetes in women than men. WHR may be the best predictor of diabetes risk in both sex of Dong ethnicity and Miao men, and VAI may be the best predictor of diabetes risk in Miao women.
    Keywords Medicine ; R ; Science ; Q
    Subject code 571
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

To top