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  1. AU=Khan Israr
  2. AU="Ansary, Delwar"
  3. AU="Gamerra, Mario"
  4. AU="Eric M. Yoshida"
  5. AU="Raj, Rahul"
  6. AU="Semaan, Marie"
  7. AU="Trafton, Jodie"
  8. AU="Victoria Walker-Sperling"
  9. AU="Song, Wuqi"
  10. AU="Pham, K.‐C"
  11. AU="Boria Alegre, Felix"
  12. AU="Vecsey-Nagy, Milán"
  13. AU=Bazak Remon
  14. AU="Shaaban, Mahmoud"
  15. AU="Perminow, Gøri"
  16. AU="Akrim, Faraz"
  17. AU="Haider, Najm"
  18. AU="Jain, Divyanu"
  19. AU="Halpert, Richard"
  20. AU="Alkorta, Ibon"
  21. AU="Kwon, Kyungmi"
  22. AU="Bernardo Salasnich"
  23. AU="Hassan, Zurina"
  24. AU="Belarbi, M"
  25. AU="Rout, Ranjeet K"
  26. AU="Moreira, Catarina"
  27. AU=Warn-Cramer Bonnie J
  28. AU="Morral, Núria"
  29. AU="Silman, Miles R."
  30. AU="Palfi Salavat, Mădălina-Casiana"
  31. AU="Mohamed, Eid"
  32. AU="Hudson, Lance"
  33. AU="Imane Mihoub" AU="Imane Mihoub"
  34. AU="D. M. Wuchenich"

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  1. Artikel: Alpha-linolenic acid given as an anti-inflammatory agent in a mouse model of colonic inflammation

    Khan, Israr / zhang, chunjiang

    Food Science & Nutrition, 7(12):3873-3882

    2019  

    Abstract: This study examined the relationship between the high-fat, high-sugar diet (HFHSD) and trinitrobenzene sulfonic acid (TNBS) induced mouse colitis, the therapeutic effect of alpha-linolenic acid (ALA) on mouse colitis, and the relationship between HFHSD ... ...

    Abstract This study examined the relationship between the high-fat, high-sugar diet (HFHSD) and trinitrobenzene sulfonic acid (TNBS) induced mouse colitis, the therapeutic effect of alpha-linolenic acid (ALA) on mouse colitis, and the relationship between HFHSD and hyperlipidemia. We also examined the possible underlying mechanisms behind their interactions. Female BABL/c mice were fed with HFHSD for the 9 weeks. At the same time, ALA treatment (150 or 300 mg/kg) was administered on a daily basis. At the end of the 9 weeks, experimental colitis was induced by the intra-colonic administration of TNBS. Body weight, spleen weight, disease activity index (DAI), histological changes, T-cell-related cytokine level, and lipid profiles were measured after treatment. TNBS induced severe clinical manifestations of colitis and histological damage. Low-ALA (150 mg/kg) administration profoundly ameliorated TNBS-induced clinical manifestations, body weight loss, spleen weight loss, and histological damage. On the contrary, the high-ALA (300 mg/kg) administration did not ameliorate colitis and even exacerbated the symptoms. HFHSD consumption assisted TNBS in changing IL-12, IFN-γ, IL-2, and IL-17A in the liver. As expected, these changes were recovered through low-ALA. In addition, HFHSD had a significant impact on the total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), and triglyceride (TG), which related to the increased risk of hyperlipidemia. In summation, HFHSD exacerbated the TNBS-induced colitis via the Th1/Th17 pathway. The Low-ALA (150 mg/kg) exhibited protective effects against the TNBS-induced colitis via the Th1/Th2/Th17 pathway.
    Schlagwörter T‐cell‐related cytokines ; inflammatory bowel disease ; α‐linolenic acid
    Sprache Englisch
    Dokumenttyp Artikel
    Datenquelle Fachrepositorium Lebenswissenschaften

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  2. Artikel: An unusual presentation of takotsubo syndrome in an elderly patient.

    Khan, Israr / Atoot, Adam

    Oxford medical case reports

    2024  Band 2024, Heft 2, Seite(n) omad144

    Abstract: Takotsubo syndrome occurs predominantly in women and is usually preceded by acute emotional and/or physical stress. Patients commonly present with chest pain and/or dyspnea. Syncope or out-of-hospital cardiac arrest is a rare presentation. We report an ... ...

    Abstract Takotsubo syndrome occurs predominantly in women and is usually preceded by acute emotional and/or physical stress. Patients commonly present with chest pain and/or dyspnea. Syncope or out-of-hospital cardiac arrest is a rare presentation. We report an unusual case of takotsubo syndrome in an elderly patient who presented with left facial droop, slurred speech, and syncopal episode. Initial presumed diagnosis was an ischemic stroke/transient ischemic attack. However, the patient was then treated for acute myocardial ischemia/infarction based on abnormal electrocardiogram, elevated cardiac troponin, and unremarkable neurological workup. Eventually diagnosed with takotsubo syndrome. Our case illustrates the importance of prompt identification particularly in the context of atypical presentation and further evaluation to rule out serious causes to mitigate related morbidity and mortality while simultaneously avoiding unnecessary investigations.
    Sprache Englisch
    Erscheinungsdatum 2024-02-16
    Erscheinungsland England
    Dokumenttyp Case Reports
    ZDB-ID 2766251-2
    ISSN 2053-8855
    ISSN 2053-8855
    DOI 10.1093/omcr/omad144
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Patient with altered mental status.

    Khan, Israr / Atoot, Adam

    Heart (British Cardiac Society)

    2023  Band 109, Heft 14, Seite(n) 1063–1122

    Mesh-Begriff(e) Humans ; Bradycardia ; Mental Disorders/diagnosis ; Mental Disorders/therapy
    Sprache Englisch
    Erscheinungsdatum 2023-06-26
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 1303417-0
    ISSN 1468-201X ; 1355-6037
    ISSN (online) 1468-201X
    ISSN 1355-6037
    DOI 10.1136/heartjnl-2023-322474
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  4. Artikel ; Online: Effect of stocking density on performance, survival and nutrient composition of super worm Zophobas Morio (Coleoptera:Tenebrionidae).

    Khan, Sar Zamin / Usman, Amjad / Khan, Kamran / Tanveer, Jabbar / Israr, Mohammad

    Tropical animal health and production

    2024  Band 56, Heft 2, Seite(n) 95

    Abstract: As the global demand for animal protein continues to increase, the need for sustainable and resource-efficient alternatives for animal feed becomes increasingly paramount. Insects have gained significant attention as promising candidates to support the ... ...

    Abstract As the global demand for animal protein continues to increase, the need for sustainable and resource-efficient alternatives for animal feed becomes increasingly paramount. Insects have gained significant attention as promising candidates to support the sustainable development of the feed industry, and their utilization in animal feed has seen substantial growth in recent years. Therefore, this study was conducted to optimize the superworm (Zophobas morio) larvae rearing stocking density on the biomass production, survival, and nutrient composition. Two-weeks-old Z. morio larvae were maintained at 25 ± 2
    Mesh-Begriff(e) Animals ; Coleoptera ; Larva ; Nutrients ; Animal Feed ; Biomass
    Sprache Englisch
    Erscheinungsdatum 2024-03-05
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 603363-5
    ISSN 1573-7438 ; 0049-4747
    ISSN (online) 1573-7438
    ISSN 0049-4747
    DOI 10.1007/s11250-024-03935-x
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  5. Artikel: Revolutionizing Cancer Care: Advances in Carbon-Based Materials for Diagnosis and Treatment.

    Khan, Muhammad Zubair / Tahir, Danial / Asim, Muhammad / Israr, Muhammad / Haider, Ali / Xu, Dan Dan

    Cureus

    2024  Band 16, Heft 1, Seite(n) e52511

    Abstract: Cancer involves intricate pathological mechanisms marked by complexities such as cytotoxicity, drug resistance, stem cell proliferation, and inadequate specificity in current chemotherapy approaches. Cancer therapy has embraced diverse nanomaterials ... ...

    Abstract Cancer involves intricate pathological mechanisms marked by complexities such as cytotoxicity, drug resistance, stem cell proliferation, and inadequate specificity in current chemotherapy approaches. Cancer therapy has embraced diverse nanomaterials renowned for their unique magnetic, electrical, and optical properties to address these challenges. Despite the expanding corpus of knowledge in this area, there has been less advancement in approving nano drugs for use in clinical settings. Nanotechnology, and more especially the development of intelligent nanomaterials, has had a profound impact on cancer research and treatment in recent years. Due to their large surface area, nanoparticles can adeptly encapsulate diverse compounds. Furthermore, the modification of nanoparticles is achievable through a broad spectrum of bio-based substrates, including DNA, aptamers, RNA, and antibodies. This functionalization substantially enhances their theranostic capabilities. Nanomaterials originating from biological sources outperform their conventionally created counterparts, offering advantages such as reduced toxicity, lower manufacturing costs, and enhanced efficiency. This review uses carbon nanomaterials, including graphene-based materials, carbon nanotubes (CNTs) based nanomaterials, and carbon quantum dots (CQDs), to give a complete overview of various methods used in cancer theranostics. We also discussed their advantages and limitations in cancer diagnosis and treatment settings. Carbon nanomaterials might significantly improve cancer theranostics and pave the way for fresh tumor diagnosis and treatment approaches. More study is needed to determine whether using nano-carriers for targeted medicine delivery may increase material utilization. More insight is required to explore the correlation between heightened cytotoxicity and retention resulting from increased permeability.
    Sprache Englisch
    Erscheinungsdatum 2024-01-18
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.52511
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  6. Artikel ; Online: Frequency of Amblyopia in strabismus patients presenting to tertiary care hospital.

    Zahir, Khalil Khan / Israr, Muhammad / Khattak, Muhammad Adnan Khan / Mudassar, Saman / Shaheen, Samia / Ullah, Irfan

    Romanian journal of ophthalmology

    2023  Band 67, Heft 1, Seite(n) 46–49

    Abstract: Objective: ...

    Abstract Objective:
    Mesh-Begriff(e) Humans ; Amblyopia/epidemiology ; Amblyopia/diagnosis ; Cross-Sectional Studies ; Tertiary Care Centers ; Strabismus/complications ; Strabismus/epidemiology ; Strabismus/diagnosis ; Ophthalmology
    Sprache Englisch
    Erscheinungsdatum 2023-04-05
    Erscheinungsland Romania
    Dokumenttyp Journal Article
    ZDB-ID 2842202-8
    ISSN 2501-2533 ; 2457-4325
    ISSN (online) 2501-2533
    ISSN 2457-4325
    DOI 10.22336/rjo.2023.8
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  7. Artikel ; Online: Evaluation of biological selenium nanoparticles on growth performance, histopathology of vital organs and genotoxicity in Japanese quails (

    Naz, Shabana / Bibi, Gulnaz / Nadeem, Rida / A Alhidary, Ibrahim / Dai, Sifa / Israr, Muhammad / Ullah Khan, Rifat

    The veterinary quarterly

    2024  Band 44, Heft 1, Seite(n) 1–10

    Abstract: Research on the effects of selenium nanoparticles (Se-NPs), particularly in Japanese quails, is lacking, especially regarding the potential for DNA damage. Therefore, this study aimed to investigate the impact of administering 0.2 and 0.4 mg/kg of Se-NPs ...

    Abstract Research on the effects of selenium nanoparticles (Se-NPs), particularly in Japanese quails, is lacking, especially regarding the potential for DNA damage. Therefore, this study aimed to investigate the impact of administering 0.2 and 0.4 mg/kg of Se-NPs on the growth performance, DNA integrity, and histopathological alterations of the liver, lung, kidney, and heart in quails. A total of 480 one-day-old Japanese quails were divided into three experimental groups as follows: Group 1 served as the control and received only basic feed, while Group 2 and 3 received 0.2 mg/kg and 0.4 mg/kg of Se-NPs
    Mesh-Begriff(e) Animals ; Coturnix ; Selenium/toxicity ; Dietary Supplements ; Weight Gain ; DNA Damage ; Animal Feed/analysis ; Diet/veterinary
    Chemische Substanzen Selenium (H6241UJ22B)
    Sprache Englisch
    Erscheinungsdatum 2024-04-01
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 754161-2
    ISSN 1875-5941 ; 0165-2176
    ISSN (online) 1875-5941
    ISSN 0165-2176
    DOI 10.1080/01652176.2024.2319830
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  8. Artikel ; Online: Impact of coriander (

    Hafeez, Abdul / Shahid Ali, Said / Akhtar, Junaid / Naz, Shabana / Alrefaei, Abdulwahed Fahad / Albeshr, Mohammed Fahad / Israr, Muhammad / Ullah Khan, Rifat

    The veterinary quarterly

    2024  Band 44, Heft 1, Seite(n) 1–7

    Abstract: The study investigated the impact of incorporating a specific herbal blend comprising coriander, garlic, and fenugreek (CGF) at various levels on the zootechnical performance, blood metabolites and nutrient digestibility in broiler chickens. The 42-day ... ...

    Abstract The study investigated the impact of incorporating a specific herbal blend comprising coriander, garlic, and fenugreek (CGF) at various levels on the zootechnical performance, blood metabolites and nutrient digestibility in broiler chickens. The 42-day experiment involved 360 broilers (Cobb 500), organized into four distinct treatment groups. The dietary interventions included a control group consisting of a basal diet and the same diet was supplemented with CGF at rates of 1, 2, and 3%. Broilers receiving a 1% phytogenic mixture exhibited significantly increased live weight and carcass weight. Moreover, the digestibility of crude protein and crude fat significantly improved in broilers supplemented with a 1% phytogenic mixture. On the other hand, the digestibility of calcium and phosphorus showed a notable increase in broilers fed with a 3% phytogenic mixture. Regarding serum metabolites, the 1% phytogenic mixture group displayed significantly higher levels of high density lipoprotein and triglycerides. The supplementation of the broiler diet with a herbal mixture of coriander, fenugreek, and garlic at a 1% rate resulted in improved growth performance, carcass quality, nutrient digestion, and lipid profile.
    Mesh-Begriff(e) Animals ; Garlic ; Coriandrum ; Chickens ; Trigonella ; Nutrients
    Sprache Englisch
    Erscheinungsdatum 2024-02-29
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 754161-2
    ISSN 1875-5941 ; 0165-2176
    ISSN (online) 1875-5941
    ISSN 0165-2176
    DOI 10.1080/01652176.2023.2300948
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  9. Artikel ; Online: Evaluating Corporate Performance and Bank Productivity in China

    Israr Khan / Mansi Wang

    Sustainability, Vol 13, Iss 3193, p

    The Moderating Role of Independent Directors

    2021  Band 3193

    Abstract: Corporate governance (CG) is not an abstract goal. It exists to serve the bank’s purpose by giving a framework through which investors, directors, and the top management can efficiently follow its objectives. Subsequently, it boosts the financial ... ...

    Abstract Corporate governance (CG) is not an abstract goal. It exists to serve the bank’s purpose by giving a framework through which investors, directors, and the top management can efficiently follow its objectives. Subsequently, it boosts the financial performance of the bank for its shareholders. This paper explores CG and its impacts on financial performance from the evidence collected from selected commercial banks (CB) in China. The data sample for this research comprises selected CBs in China for the period from 2008 to 2019. Applying selection standards provides us a data sample of 17 CBs. We employed the generalized method of moments (GMM) regression model constructed on 170 observations to identify the variables’ relationship. Our findings show that female independent directors positively and significantly affect bank financial performance. Despite the literature review, we found that the existence of female directors alone does not positively and significantly improve banks’ financial performance. The finding suggests that female directors are more efficient when they are selected as independent directors. The findings show that CEO duality affects bank financial performance positively and significantly. CEO duality strengthens the financial performance of CBs because of the solidarity of the order it presents. The results also show that CEO shareholding and financial performance of Chinese CBs have a positively significant bond with each other. This result suggests that a blend of CG instruments is more impressive than one CG component. The investigation results added a new dimension to the governance literature that could be an important source of knowledge for policymakers and regulators to improve the current governance structure for better performance across countries. This paper support principal-agent theory and the author also provide some help for the theories that regulators should support gender quotas in the board of directors of banks to decrease risk-taking behavior.
    Schlagwörter board gender diversity ; CEO duality ; ownership ; moderating variable ; financial performance ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Thema/Rubrik (Code) 332
    Sprache Englisch
    Erscheinungsdatum 2021-03-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
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  10. Artikel ; Online: Slope Stability Analysis to Correlate Shear Strength with Slope Angle and Shear Stress by Considering Saturated and Unsaturated Seismic Conditions

    Muhammad Israr Khan / Shuhong Wang

    Applied Sciences, Vol 11, Iss 4568, p

    2021  Band 4568

    Abstract: Assessment and analysis of soil slope stability is an important part of geotechnical engineering at all times. This paper examines the assessment of soil slope stability in fine-grained soils. The effect of change in shear strength (τ), shear stress (σ) ... ...

    Abstract Assessment and analysis of soil slope stability is an important part of geotechnical engineering at all times. This paper examines the assessment of soil slope stability in fine-grained soils. The effect of change in shear strength (τ), shear stress (σ) and slope angle (β) on the factor of safety has been studied. It correlates shear strength with slope angle and shear stress by considering the horizontal seismic coefficients in both saturated and unsaturated conditions. The slope failure surface was considered a circular slip surface. Statistical package for social sciences (SPSS) and Slide, numerical modeling software and limit equilibrium slope stability analysis software, respectively, are used to find out the correlations between the three basic parameters. The slope angle varied from 70 to 88 degrees, which are the most critical values for slope angles, and a total of 200 analyses were performed. τ, β and σ are correlated, and the correlations are provided in the results section. The results indicate that the correlations developed between the parameters have a very close relationship. The applicability of the developed equations is above 99%. These correlations are applicable in any type of soil slope stability analysis, where the value of shear strength and factor of safety is required with the variation of slope angle and shear stress.
    Schlagwörter slope stability analysis ; shear strength ; slope angle ; shear stress ; correlations ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
    Thema/Rubrik (Code) 690
    Sprache Englisch
    Erscheinungsdatum 2021-05-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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