LIVIVO - Search results -

Search results

Result 1 - 10 of total 98

Search options

Article: Rituximab for Pediatric Central Nervous System Inflammatory Disorders in Alberta, Canada.

Pecuh, Ihor / Slobodan, Jeremy / McCombe, Jennifer A / Morneau-Jacob, Francois-Dominique / Smyth, Penelope / Wilbur, Colin

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques

2023 Volume 51, Issue 1, Page(s) 50–56

Abstract: Background: Early and effective treatment of central nervous system (CNS) inflammatory disorders is vital to reduce neurologic morbidity and improve long-term outcomes in affected children. Rituximab is a B-cell-depleting monoclonal antibody whose off- ... ...

Abstract	Background: Early and effective treatment of central nervous system (CNS) inflammatory disorders is vital to reduce neurologic morbidity and improve long-term outcomes in affected children. Rituximab is a B-cell-depleting monoclonal antibody whose off-label use for these disorders is funded in the province of Alberta, Canada, by the Short-Term Exceptional Drug Therapy (STEDT) program. This study describes the use of rituximab for pediatric CNS inflammatory disorders in Alberta. Methods: Rituximab applications for CNS inflammatory indications in patients <18 years of age were identified from the STEDT database between January 1, 2012, and December 31, 2019. Patient information was linked to other provincial datasets including the Discharge Abstract Database, Pharmaceutical Information Network, and Provincial Laboratory data. Analysis was descriptive. Results: Fifty-one unique rituximab applications were identified, of which 50 were approved. New applications increased from one in 2012 to a high of 12 in 2018. The most common indication was autoimmune encephalitis without a specified antibody ( Conclusion: The use of rituximab for pediatric CNS inflammatory disorders has increased, particularly for the indication of autoimmune encephalitis. This study identified significant heterogeneity in dosing practices and laboratory monitoring. Standardized protocols for the use of rituximab in these disorders and more robust outcome reporting will help better define the safety and efficacy of rituximab in this population.
MeSH term(s)	Humans ; Child ; Rituximab/therapeutic use ; Alberta/epidemiology ; Antibodies ; Central Nervous System Diseases/drug therapy ; Autoimmune Diseases of the Nervous System/drug therapy ; Central Nervous System ; Encephalitis ; Hashimoto Disease
Chemical Substances	Rituximab (4F4X42SYQ6) ; Antibodies
Language	English
Publishing date	2023-01-30
Publishing country	England
Document type	Journal Article
ZDB-ID	197622-9
ISSN	0317-1671
ISSN	0317-1671
DOI	10.1017/cjn.2023.16
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 1203: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾

Article ; Online: Teaching NeuroImages: The curious case of the brainstem kink.

Srivastava, Ratika / Morneau-Jacob, Francois-Dominique

Neurology

2019 Volume 92, Issue 16, Page(s) e1933–e1934

MeSH term(s)	Adult ; Brain Stem/diagnostic imaging ; Brain Stem/growth & development ; Diagnosis, Differential ; Female ; Humans ; Magnetic Resonance Imaging ; Nucleotidyltransferases/genetics ; Pregnancy ; Prenatal Diagnosis ; Walker-Warburg Syndrome/diagnostic imaging ; Walker-Warburg Syndrome/genetics
Chemical Substances	Nucleotidyltransferases (EC 2.7.7.-) ; CRPPA protein, human (EC 2.7.7.40)
Language	English
Publishing date	2019-04-12
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	207147-2
ISSN	1526-632X ; 0028-3878
ISSN (online)	1526-632X
ISSN	0028-3878
DOI	10.1212/WNL.0000000000007320
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ui II Zs.153: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MG 18: Show issues
Zs.MO 374: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Patterns of Brain Injury in Perinatal Arterial Ischemic Stroke and the Development of Infantile Spasms.

Srivastava, Ratika / Shaw, Oriana E F / Armstrong, Edward / Morneau-Jacob, Francois-Dominique / Yager, Jerome Y

Journal of child neurology

2021 Volume 36, Issue 7, Page(s) 583–588

Abstract: Introduction: Perinatal arterial ischemic stroke (PAIS) underlies approximately 10% of infantile spasms (IS). We aim to identify patterns of brain injury in ischemic stroke that may predispose infants to infantile spasms.: Methods: Sixty-four ... ...

Abstract	Introduction: Perinatal arterial ischemic stroke (PAIS) underlies approximately 10% of infantile spasms (IS). We aim to identify patterns of brain injury in ischemic stroke that may predispose infants to infantile spasms. Methods: Sixty-four perinatal arterial ischemic stroke patients were identified meeting the following inclusion criteria: term birth, magnetic resonance imaging (MRI) showing ischemic stroke or encephalomalacia in an arterial distribution, and follow-up records. Patients who developed infantile spasms (PAIS-IS) were analyzed descriptively for ischemic stroke injury patterns and were compared to a seizure-free control group (PAIS-only). Stroke injury was scored using the modified pediatric ASPECTS (modASPECTS). Results: The PAIS-IS (n = 9) group had significantly higher modASPECTS than the PAIS-only (n = 16) group ( Conclusion: Infarct size was significantly associated with infantile spasms development. Results support theories implicating deep cerebral structures in infantile spasms pathogenesis. This may help identify perinatal arterial ischemic stroke patients at risk of infantile spasms, facilitating more timely diagnosis.
MeSH term(s)	Brain Injuries/complications ; Brain Injuries/diagnostic imaging ; Female ; Humans ; Infant ; Infant, Newborn ; Ischemic Stroke/complications ; Ischemic Stroke/diagnostic imaging ; Magnetic Resonance Imaging ; Male ; Prognosis ; Retrospective Studies ; Risk Factors ; Spasms, Infantile/diagnosis ; Spasms, Infantile/epidemiology
Language	English
Publishing date	2021-02-05
Publishing country	United States
Document type	Journal Article ; Observational Study
ZDB-ID	639288-x
ISSN	1708-8283 ; 0883-0738
ISSN (online)	1708-8283
ISSN	0883-0738
DOI	10.1177/0883073820986056
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2301: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Book ; Online: PREMHYCE

Nicolle, Pierre / Besson, François / Delaigue, Olivier / Etchevers, Pierre / François, Didier / Lay, Matthieu / Perrin, Charles / Rousset, Fabienne / Thiéry, Dominique / Tilmant, François / Magand, Claire / Leurent, Timothée / Jacob, Élise

eISSN: 2199-899X

An operational tool for low-flow forecasting

2020

Abstract: ... Several French institutions (Inrae, BRGM, Météo-France, EDF and Lorraine University) have been collaborating over ... in real time on 70 catchments in continental France in 2017, and on 48 additional catchments in 2018 ... These climatic data (precipitation, potential evapotranspiration and temperature) are provided by Météo-France ...

Abstract	In many countries, rivers are the primary supply of water. A number of uses are concerned (drinking water, irrigation, hydropower, etc.) and they can be strongly affected by water shortages. Therefore, there is a need for the early anticipation of low-flow periods to improve water management. This is strengthened by the perspective of having more severe summer low flows in the context of climate change. Several French institutions (Inrae, BRGM, Météo-France, EDF and Lorraine University) have been collaborating over the last years to develop an operational tool for low-flow forecasting, called PREMHYCE. It was tested in real time on 70 catchments in continental France in 2017, and on 48 additional catchments in 2018. PREMHYCE includes five hydrological models: one uncalibrated physically-based model and four storage-type models of various complexity, which are calibrated on gauged catchments. The models assimilate flow observations or implement post-processing techniques. Low-flow forecasts can be issued up to 90 d ahead, based on ensemble streamflow prediction (ESP) using historical climatic data as ensembles of future input scenarios. These climatic data (precipitation, potential evapotranspiration and temperature) are provided by Météo-France with the daily gridded SAFRAN reanalysis over the 1958–2017 period, which includes a wide range of conditions. The tool provides numerical and graphical outputs, including the forecasted ranges of low flows, and the probability to be under low-flow warning thresholds provided by the users. Outputs from the different hydrological models can be combined through a simple multi-model approach to improve the robustness of forecasts. Results are illustrated for the Ill River at Didenheim (northeastern France) where the 2017 low-flow period was particularly severe and for which PREMHYCE provided useful forecasts.
Subject code	333
Language	English
Publishing date	2020-09-16
Publishing country	de
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Long-distance, synchronized and directional fall movements suggest migration in Arctic hares on Ellesmere Island (Canada)

Jacob Caron-Carrier / Sandra Lai / François Vézina / Andrew Tam / Dominique Berteaux

Scientific Reports, Vol 12, Iss 1, Pp 1-

2022 Volume 11

Abstract: Abstract Animal migration contributes largely to the seasonal dynamics of High Arctic ecosystems, linking distant habitats and impacting ecosystem structure and function. In polar deserts, Arctic hares are abundant herbivores and important components of ... ...

Abstract	Abstract Animal migration contributes largely to the seasonal dynamics of High Arctic ecosystems, linking distant habitats and impacting ecosystem structure and function. In polar deserts, Arctic hares are abundant herbivores and important components of food webs. Their annual migrations have long been suspected, but never confirmed. We tracked 25 individuals with Argos satellite telemetry to investigate the existence of migration in a population living at Alert (Ellesmere Island, Nunavut, Canada). During fall, 21 hares undertook directional, long-distance movements in a southwestern direction towards Lake Hazen. Daily movement rates averaged 1.3 ± 0.5 km, 4.3 ± 1.6 km, and 1.7 ± 0.9 km before, during, and after relocation, respectively. Straight-line and minimum cumulative distances traveled averaged 98 ± 18 km (range: 72–148 km) and 198 ± 62 km (range: 113–388 km), respectively. This is the first report of large-scale seasonal movements in Arctic hares and, surprisingly, in any lagomorph species. These movements may be part of an annual migratory pattern. Our results redefine our understanding of the spatial ecology of Arctic hares, demonstrate unsuspected mobility capacities in lagomorphs, and open new perspectives regarding the ecological dynamics of the northern polar deserts.
Keywords	Medicine ; R ; Science ; Q
Language	English
Publishing date	2022-03-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Preservation of language in the ataxic infant in a case of cerebellar agenesis.

Jacob, Francois Dominique / Goez, Helly R

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques

2009 Volume 38, Issue 1, Page(s) 143–144

MeSH term(s)	Ataxia/pathology ; Ataxia/physiopathology ; Cerebellum/abnormalities ; Disease Progression ; Humans ; Infant ; Language ; Magnetic Resonance Imaging/methods ; Male
Language	English
Publishing date	2009-10-10
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	197622-9
ISSN	0317-1671
ISSN	0317-1671
DOI	10.1017/s0317167100011203
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 1203: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Long-distance, synchronized and directional fall movements suggest migration in Arctic hares on Ellesmere Island (Canada).

Caron-Carrier, Jacob / Lai, Sandra / Vézina, François / Tam, Andrew / Berteaux, Dominique

Scientific reports

2022 Volume 12, Issue 1, Page(s) 5003

Abstract: Animal migration contributes largely to the seasonal dynamics of High Arctic ecosystems, linking distant habitats and impacting ecosystem structure and function. In polar deserts, Arctic hares are abundant herbivores and important components of food webs. ...

Abstract	Animal migration contributes largely to the seasonal dynamics of High Arctic ecosystems, linking distant habitats and impacting ecosystem structure and function. In polar deserts, Arctic hares are abundant herbivores and important components of food webs. Their annual migrations have long been suspected, but never confirmed. We tracked 25 individuals with Argos satellite telemetry to investigate the existence of migration in a population living at Alert (Ellesmere Island, Nunavut, Canada). During fall, 21 hares undertook directional, long-distance movements in a southwestern direction towards Lake Hazen. Daily movement rates averaged 1.3 ± 0.5 km, 4.3 ± 1.6 km, and 1.7 ± 0.9 km before, during, and after relocation, respectively. Straight-line and minimum cumulative distances traveled averaged 98 ± 18 km (range: 72-148 km) and 198 ± 62 km (range: 113-388 km), respectively. This is the first report of large-scale seasonal movements in Arctic hares and, surprisingly, in any lagomorph species. These movements may be part of an annual migratory pattern. Our results redefine our understanding of the spatial ecology of Arctic hares, demonstrate unsuspected mobility capacities in lagomorphs, and open new perspectives regarding the ecological dynamics of the northern polar deserts.
MeSH term(s)	Animal Migration ; Animals ; Arctic Regions ; Canada ; Ecosystem ; Hares ; Lagomorpha ; Seasons
Language	English
Publishing date	2022-03-23
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-022-08347-1
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Long-term survival and late onset seizures in an adolescent with trisomy 13.

Jacob, Francois Dominique / Ramaswamy, Vijay / Kolski, Hanna

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques

2009 Volume 37, Issue 5, Page(s) 694–696

MeSH term(s)	Adolescent ; Chromosomes, Human, Pair 13 ; Electroencephalography/methods ; Female ; Humans ; Magnetic Resonance Imaging/methods ; Seizures/diagnosis ; Seizures/genetics ; Seizures/mortality ; Trisomy
Language	English
Publishing date	2009-10-10
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	197622-9
ISSN	0317-1671
ISSN	0317-1671
DOI	10.1017/s0317167100010933
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 1203: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article: Acquired monocular nystagmus as the initial presenting sign of a chiasmal glioma.

Jacob, Francois Dominique / Ramaswamy, Vijay / Goez, Helly R

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques

2009 Volume 37, Issue 1, Page(s) 96–97

MeSH term(s)	Anemia, Iron-Deficiency/complications ; Glioma/complications ; Glioma/diagnosis ; Humans ; Infant ; Magnetic Resonance Imaging/methods ; Male ; Nystagmus, Pathologic/diagnosis ; Nystagmus, Pathologic/etiology ; Optic Nerve Glioma/complications ; Optic Nerve Glioma/diagnosis
Language	English
Publishing date	2009-11-16
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	197622-9
ISSN	0317-1671
ISSN	0317-1671
DOI	10.1017/s0317167100009719
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 1203: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: ARF1

de Sainte Agathe, Jean-Madeleine / Pode-Shakked, Ben / Naudion, Sophie / Michaud, Vincent / Arveiler, Benoit / Fergelot, Patricia / Delmas, Jean / Keren, Boris / Poirsier, Céline / Alkuraya, Fowzan S / Tabarki, Brahim / Bend, Eric / Davis, Kellie / Bebin, Martina / Thompson, Michelle L / Bryant, Emily M / Wagner, Matias / Hannibal, Iris / Lenberg, Jerica /

Krenn, Martin / Wigby, Kristen M / Friedman, Jennifer R / Iascone, Maria / Cereda, Anna / Miao, Térence / LeGuern, Eric / Argilli, Emanuela / Sherr, Elliott / Caluseriu, Oana / Tidwell, Timothy / Bayrak-Toydemir, Pinar / Hagedorn, Caroline / Brugger, Melanie / Vill, Katharina / Morneau-Jacob, Francois-Dominique / Chung, Wendy / Weaver, Kathryn N / Owens, Joshua W / Husami, Ammar / Chaudhari, Bimal P / Stone, Brandon S / Burns, Katie / Li, Rachel / de Lange, Iris M / Biehler, Margaux / Ginglinger, Emmanuelle / Gérard, Bénédicte / Stottmann, Rolf W / Trimouille, Aurélien

Journal of medical genetics

2023 Volume 60, Issue 10, Page(s) 999–1005

Abstract: Purpose: ARF1: Methods: We collected detailed phenotypes of an international cohort of individuals (n=17) with : Results: De novo variants (10 missense, 1 frameshift, 1 splice altering resulting in 9 residues insertion) in : Conclusion: We ... ...

Abstract	Purpose: ARF1 Methods: We collected detailed phenotypes of an international cohort of individuals (n=17) with Results: De novo variants (10 missense, 1 frameshift, 1 splice altering resulting in 9 residues insertion) in Conclusion: We confirm the role of
MeSH term(s)	Humans ; Brain/diagnostic imaging ; Genotype ; Intellectual Disability/genetics ; Microcephaly ; Periventricular Nodular Heterotopia ; Phenotype ; Seizures/genetics
Chemical Substances	ARF1 protein, human (EC 3.6.5.2)
Language	English
Publishing date	2023-04-25
Publishing country	England
Document type	Journal Article
ZDB-ID	220881-7
ISSN	1468-6244 ; 0022-2593
ISSN (online)	1468-6244
ISSN	0022-2593
DOI	10.1136/jmg-2022-108803
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 177: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito