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  1. Book ; Conference proceedings: Christian Vogt Photographic essays on space

    Jehle-Schulte Strathaus, Ulrike / Vogt, Christian

    2006  

    Title variant Photographic essays on space
    Institution Architekturmuseum
    Event/congress Ausstellung Christian Vogt Photographic essays on space (2006.04.08-05.28, Basel) ; Ausstellung. Schweizerisches Architekturmuseum (2006.04.08-05.28, Basel)
    Author's details AM, Schweizerisches Architekturmuseum. [Hrsg./ed.: Ulrike Jehle-Schulte Strathaus]
    Keywords Photography, Artistic ; Fotografie
    Language German ; English
    Size 62 S, 33 farb. Fotos, 25 cm
    Publisher Merian
    Publishing place Basel
    Document type Book ; Conference proceedings
    Note Text dt. und engl.
    ISBN 3856162836 ; 9783856162832
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  2. Article ; Online: Patient leaflets on respiratory tract infections did not improve shared decision making and antibiotic prescriptions in a low-prescriber setting.

    Plate, Andreas / Di Gangi, Stefania / Garzoni, Christian / Selby, Kevin / Pichierri, Giuseppe / Senn, Oliver / Neuner-Jehle, Stefan

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 4978

    Abstract: Patient information leaflets can reduce antibiotic prescription rates by improving knowledge and encouraging shared decision making (SDM) in patients with respiratory tract infections (RTI). The effect of these interventions in antibiotic low-prescriber ... ...

    Abstract Patient information leaflets can reduce antibiotic prescription rates by improving knowledge and encouraging shared decision making (SDM) in patients with respiratory tract infections (RTI). The effect of these interventions in antibiotic low-prescriber settings is unknown. We conducted a pragmatic pre-/post interventional study between October 2022 and March 2023 in Swiss outpatient care. The intervention was the provision of patient leaflets informing about RTIs and antibiotics use. Main outcomes were the extent of SDM, antibiotic prescription rates, and patients' awareness/knowledge about antibiotic use in RTIs. 408 patients participated in the pre-intervention period, and 315 patients in the post- intervention period. There was no difference in the extent of SDM (mean score (range 0-100): 65.86 vs. 64.65, p = 0.565), nor in antibiotic prescription rates (no prescription: 89.8% vs. 87.2%, p = 0.465) between the periods. Overall awareness/knowledge among patients with RTI was high and leaflets showed only a small effect on overall awareness/knowledge. In conclusion, in an antibiotic low-prescriber setting, patient information leaflets may improve knowledge, but may not affect treatment decisions nor antibiotic prescription rates for RTIs.
    MeSH term(s) Humans ; Decision Making, Shared ; Anti-Bacterial Agents/therapeutic use ; Respiratory Tract Infections/drug therapy ; Drug Prescriptions ; Publications ; Practice Patterns, Physicians'
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2024-02-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-55166-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Clinical Characteristics and Laboratory Biomarkers for Patients with Suspected COVID-19 Infection Within HCA Healthcare.

    Gutovitz, Scott / Hanson, Justin / Vandever, Christian / Jehle, Dietrich

    HCA healthcare journal of medicine

    2021  Volume 2, Issue 3, Page(s) 229–236

    Abstract: Background: The coronavirus infection (COVID-19), also known as the Severe Acute Respiratory Syndrome Virus 2 (SARS-CoV-2), caused significant illness and a worldwide pandemic beginning in 2020. Early case reports showed common patient characteristics, ... ...

    Abstract Background: The coronavirus infection (COVID-19), also known as the Severe Acute Respiratory Syndrome Virus 2 (SARS-CoV-2), caused significant illness and a worldwide pandemic beginning in 2020. Early case reports showed common patient characteristics, clinical variables and laboratory values in these patients. We compared a large population of American COVID-19 patients to see if they had similar findings to these smaller reports. In addition, we examined our population to identify any differences between mild or severe COVID-19 infections.
    Methods: We retrospectively accessed a de-identified, multi-hospital database managed by HCA Healthcare to identify all adult emergency department (ED) patients that were tested for COVID-19 from January 1st, 2020-April 30th, 2020. We collected clinical variables, comorbidities and laboratory values to identify any differences in those with or without a SARS-CoV-2 infection.
    Results: We identified 44,807 patients who were tested for SARS-CoV-2. Of those patients, 6,158 were positive for COVID-19. Male patients were more likely to test positive than female ones (15.0% vs. 12.6%, p < 0.001). The most frequently positive tests occurred in age groups 40-49, 50-59 and 60-69 (16.9%, 15.3% and 14.1% respectively). Both African Americans (20.2%) and Hispanics (20.8%) were more likely to test positive than Caucasians (8.3%, p < 0.001). Hypertension and diabetes were more common in those with positive tests, and multiple laboratory biomarkers showed significant differences in severe infections.
    Conclusions: This broad cohort of American COVID-19 patients showed similar trends in gender, age groups and race/ethnicity as previously reported. Severe COVID-19 disease was also associated with many positive laboratory biomarkers.
    Language English
    Publishing date 2021-06-28
    Publishing country United States
    Document type Journal Article
    ISSN 2689-0216
    ISSN (online) 2689-0216
    DOI 10.36518/2689-0216.1233
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Wer wacht hier wann auf? Neues Projekt zur Studie der Diapause von Apfelwicklern gestartet

    Oehlmann, Christian / Janik, Katrin / Neulichedl, Peter / Wennmann, Jörg T. / Zeiger, Roland / Jehle, Johannes A.

    Obstbau

    2023  Volume 48, Issue 3, Page(s) 151

    Language German
    Document type Article
    ZDB-ID 820098-1
    ISSN 0179-7077
    Database Current Contents Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Z 3250: Show issues

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  5. Article ; Online: Wer wacht hier wann auf? Studie über die Diapause des Apfelwicklers

    Oehlmann, Christian / Janik, Katrin / Neulichedl, Peter / Zelger, Roland / Wennmann, Jörg T. / Jehle, Johannes A.

    2023  

    Keywords Text ; ddc:630 ; Apfelwickler -- Diapause
    Language German
    Publishing country de
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Impact of atrial fibrillation on 1-year outcome in patients with implantable cardioverter defibrillator or cardiac resynchronization therapy with defibrillator: results from the German DEVICE Registry.

    Feickert, Sebastian / Ewertsen, Niels Christian / Köbe, Julia / Kleemann, Thomas / Jehle, Joachim / Senges, Jochen / Hochadel, Matthias / Andresen, Dietrich / Stellbrink, Christoph / Eckardt, Lars / Spitzer, Stefan / Brachmann, Johannes / Ince, Hüseyin / D'Ancona, Giuseppe

    Journal of thoracic disease

    2024  Volume 16, Issue 3, Page(s) 1825–1835

    Abstract: Background: Atrial fibrillation (AF) is a cardiac arrhythmia frequently documented in patients requiring implantable cardioverter defibrillators (ICDs) and/or cardiac resynchronization therapy with defibrillator (CRT-D). Patients with diagnosed AF at ... ...

    Abstract Background: Atrial fibrillation (AF) is a cardiac arrhythmia frequently documented in patients requiring implantable cardioverter defibrillators (ICDs) and/or cardiac resynchronization therapy with defibrillator (CRT-D). Patients with diagnosed AF at the point of ICD or CRT-D implantation may have an impaired follow-up outcome.
    Methods: The German DEVICE I-II registry is a nationwide prospective multicentre database of patients implanted with ICD and CRT-D with clinical follow-up data. We analysed a 1-year follow up of implanted patients with AF and with sinus rhythm (SR).
    Results: A total of 4,929 ICD/CRT patients are included in the present analysis: 946 (19.2%) were in AF and 3,983 (80.8%) were SR at time of device implantation. AF patients had a significantly more comorbid profile including older age {72 [interquartile range (IQR), 66-77]
    Conclusions: Our clinical data on an extended cohort of contemporary patients confirm the significant impact of AF, and its associated comorbidities, upon mortality and major adverse events after implantation of ICD/CRT.
    Language English
    Publishing date 2024-03-27
    Publishing country China
    Document type Journal Article
    ZDB-ID 2573571-8
    ISSN 2077-6624 ; 2072-1439
    ISSN (online) 2077-6624
    ISSN 2072-1439
    DOI 10.21037/jtd-23-274
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Online ; Thesis: Prospektive Studie zur Monitoralarmierung auf deutschen Intensivstationen

    Kollmann-Jehle, Felix [Verfasser] / Wrede, Christian [Akademischer Betreuer]

    2020  

    Author's details Felix Kollmann-Jehle ; Betreuer: Christian Wrede
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitätsbibliothek Regensburg
    Publishing place Regensburg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

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  8. Article ; Online: Current and future water balance for coupled human-natural systems – Insights from a glacierized catchment in Peru

    Alina Motschmann / Claudia Teutsch / Christian Huggel / Jochen Seidel / Christian D. León / Randy Muñoz / Jessica Sienel / Fabian Drenkhan / Wolfgang Weimer-Jehle

    Journal of Hydrology: Regional Studies, Vol 41, Iss , Pp 101063- (2022)

    2022  

    Abstract: Study region: Santa River basin, Peru. Study focus: In the Andes of Peru, climate change and socio-economic development are expected to jeopardize future water availability. However, little is known about the interplay of multiple climatic and non- ... ...

    Abstract Study region: Santa River basin, Peru. Study focus: In the Andes of Peru, climate change and socio-economic development are expected to jeopardize future water availability. However, little is known about the interplay of multiple climatic and non-climatic stressors and related processes driving water resource changes. We developed an integrated model that analyzes different trajectories of water availability including hydro-climatic (water supply) and socio-economic (water demand) variables with consistent multi-descriptor future scenarios until 2050. New hydrological insights for the region: At the lower-basin outflow of Condorcerro, mean annual water availability is projected to increase by 10% ± 12% by 2050. This gain is mainly driven by an increase in annual precipitation amounts of about 14% (RCP2.6) and 18% (RCP8.5), respectively, which was computed using a global climate multi-model ensemble. In contrast, mean dry-season water availability is projected to substantially decrease by 33% and 36% ( ± 24%) by 2050, for RCP2.6 and RCP8.5, respectively. This decline is driven by a combination of diminishing glacier discharge and increasing water demand both of which adopt a major role in the absence of considerable precipitation inputs. These seasonal differences highlight the need to adequately consider spatiotemporal scales within multi-scenario water balance models to support local decision-making. Our results elucidate the need for improvements in water management and infrastructure to counteract diminishing dry-season water availability and to reduce future risks of water scarcity.
    Keywords Water supply ; Water demand ; Socio-hydrology ; Socio-economic scenarios ; Santa River ; Peru ; Physical geography ; GB3-5030 ; Geology ; QE1-996.5
    Language English
    Publishing date 2022-06-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Risk Factors, Manifestation, and Awareness of Osteoporosis among Patients of Various Specialists in Switzerland: Results of a National Survey.

    Jehle-Kunz, Sigrid / Häuselmann, Hans-Jörg / Keschawarzi, Mitra / Lamy, Olivier / Luzuy, Franck / Marcoli, Natalie / Meier, Christian / Uebelhart, Brigitte / Wiedersheim, Peter

    Healthcare (Basel, Switzerland)

    2022  Volume 10, Issue 2

    Abstract: Osteoporosis is the most common chronic metabolic bone disease, known to be underdiagnosed and undertreated in parts of the Swiss population. Due to expected rise in new fragility fractures, adequate awareness of associated risk factors and diagnostic ... ...

    Abstract Osteoporosis is the most common chronic metabolic bone disease, known to be underdiagnosed and undertreated in parts of the Swiss population. Due to expected rise in new fragility fractures, adequate awareness of associated risk factors and diagnostic and therapeutic options will be essential for the management of osteoporosis. We therefore explored these aspects in a nationwide survey of Swiss specialists and their patients. A total of 262 physician questionnaires and 9065 patient questionnaires were analyzed, mainly from general practitioners (64.9%), followed by rheumatologists (16.8%), gynecologists (12.2%), and endocrinologists (6.1%). Around 20% of patients were under medication and/or had a medical condition increasing the risk of osteoporosis. Further risk factors, such as low consumption of calcium-rich foods, smoking, elevated alcohol intake, and insufficient physical activity, were present across regions and medical fields. 53.9% of patients did not take calcium/vitamin D supplements; 3.5% reported having fragility fractures, and 7.3% received treatment for osteoporosis. Only 38.5% of surveyed patients knew of the chronic nature of osteoporosis, indicating rather low awareness in this population. Despite generally perceived relevance of osteoporosis for daily practice, aspects of its prevention and management varied across regions and medical fields. Raising awareness among patients and physicians will be vital for addressing osteoporosis on a national scale.
    Language English
    Publishing date 2022-02-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare10020295
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Genes and enzymes involved in the biodegradation of the quaternary carbon compound pivalate in the denitrifying Thauera humireducens strain PIV-1.

    Jacoby, Christian / Ebenau-Jehle, Christa / Saum, Katharina / Jehmlich, Nico / von Bergen, Martin / Brüls, Thomas / Boll, Matthias

    Environmental microbiology

    2022  Volume 24, Issue 7, Page(s) 3181–3194

    Abstract: Quaternary carbon-containing compounds exist in natural and fossil oil-derived products and are used in chemical and pharmaceutical applications up to industrial scale. Due to the inaccessibility of the quaternary carbon atom for a direct oxidative or ... ...

    Abstract Quaternary carbon-containing compounds exist in natural and fossil oil-derived products and are used in chemical and pharmaceutical applications up to industrial scale. Due to the inaccessibility of the quaternary carbon atom for a direct oxidative or reductive attack, they are considered as persistent in the environment. Here, we investigated the unknown degradation of the quaternary carbon-containing model compound pivalate (2,2-dimethyl-propionate) in the denitrifying bacterium Thauera humireducens strain PIV-1 (formerly Thauera pivalivorans). We provide multiple evidence for a pathway comprising the activation to pivalyl-CoA and the carbon skeleton rearrangement to isovaleryl-CoA. Subsequent reactions proceed similar to the catabolic leucine degradation pathway such as the carboxylation to 3-methylglutaconyl-CoA and the cleavage of 3-methyl-3-hydroxyglutaryl-CoA to acetyl-CoA and acetoacetate. The completed genome of Thauera humireducens strain PIV-1 together with proteomic data was used to identify pivalate-upregulated gene clusters including genes putatively encoding pivalate CoA ligase and adenosylcobalamin-dependent pivalyl-CoA mutase. A pivalate-induced gene encoding a putative carboxylic acid CoA ligase was heterologously expressed, and its highly enriched product exhibited pivalate CoA ligase activity. The results provide the first experimental insights into the biodegradation pathway of a quaternary carbon-containing model compound that serves as a blueprint for the degradation of related quaternary carbon-containing compounds.
    MeSH term(s) Anaerobiosis ; Carbon/metabolism ; Ligases/metabolism ; Proteomics ; Thauera/genetics
    Chemical Substances Carbon (7440-44-0) ; Ligases (EC 6.-)
    Language English
    Publishing date 2022-04-28
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2020213-1
    ISSN 1462-2920 ; 1462-2912
    ISSN (online) 1462-2920
    ISSN 1462-2912
    DOI 10.1111/1462-2920.16021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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