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  1. Article ; Online: Liquid Embolization of Peripheral Arteriovenous Malformations with Ethylene-Vinyl Alcohol Copolymer in Neonates and Infants.

    Pfeifer, Jochen / Wohlgemuth, Walter A / Abdul-Khaliq, Hashim

    Cardiovascular therapeutics

    2022  Volume 2022, Page(s) 1022729

    Abstract: In the postnatal period, extensive peripheral arteriovenous malformations (AVM) are associated with high morbidity, especially when localized in the liver. Their urgent treatment is always a challenging problem in neonates and infants. We analyzed four ... ...

    Abstract In the postnatal period, extensive peripheral arteriovenous malformations (AVM) are associated with high morbidity, especially when localized in the liver. Their urgent treatment is always a challenging problem in neonates and infants. We analyzed four consecutive children aged three days to three years who underwent eight liquid embolization procedures with ethylene-vinyl alcohol copolymer. The AVM were situated on the thoracic wall, in the liver, and on the lower leg. In three cases, the malformations showed total regression. The tibial AVM degenerated widely. If impaired beforehand, cardiac or hepatic function normalized after the interventions. There were no embolization-associated complications such as nontarget embolization or tissue ischemia. We conclude that application of ethylene-vinyl alcohol copolymer seems to be a safe therapeutic option and can be used in neonates and infants with peripheral AVM in consideration of the agent's characteristics. Nevertheless, there are still hardly any data concerning young children.
    MeSH term(s) Arteriovenous Malformations/drug therapy ; Arteriovenous Malformations/therapy ; Child ; Child, Preschool ; Embolization, Therapeutic/adverse effects ; Embolization, Therapeutic/methods ; Humans ; Infant, Newborn ; Polyvinyls/adverse effects ; Treatment Outcome
    Chemical Substances Polyvinyls ; ethylene-vinyl alcohol copolymer (25067-34-9)
    Language English
    Publishing date 2022-07-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2428378-2
    ISSN 1755-5922 ; 1755-5914
    ISSN (online) 1755-5922
    ISSN 1755-5914
    DOI 10.1155/2022/1022729
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2474: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Book ; Online ; Thesis: Zusammenhang zwischen abdominellen Symptomen und intestinaler Inflammation bei Patient*innen mit Cystischer Fibrose

    Pfeifer, Elena [Verfasser] / Mainz, Jochen [Gutachter] / Jochum, Thomas [Gutachter] / Kamradt, Thomas [Gutachter]

    2023  

    Author's details Elena Pfeifer ; Gutachter: Jochen Mainz, Thomas Jochum, Thomas Kamradt
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Friedrich-Schiller-Universität Jena
    Publishing place Jena
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  3. Article ; Online: Cardiac affection associated to severe Multisystem Inflammatory Syndrome in Children (MIS-C) in a 6-year-old girl with a single coronary artery.

    Pfeifer, Jochen / Fries, Peter / Thurner, Lorenz / Abdul-Khaliq, Hashim

    Clinical research in cardiology : official journal of the German Cardiac Society

    2022  Volume 111, Issue 10, Page(s) 1184–1187

    MeSH term(s) COVID-19/complications ; Child ; Coronary Artery Disease ; Female ; Heart ; Humans ; Systemic Inflammatory Response Syndrome/diagnosis ; Systemic Inflammatory Response Syndrome/etiology
    Language English
    Publishing date 2022-07-29
    Publishing country Germany
    Document type Case Reports ; Letter
    ZDB-ID 2213295-8
    ISSN 1861-0692 ; 1861-0684
    ISSN (online) 1861-0692
    ISSN 1861-0684
    DOI 10.1007/s00392-022-02060-9
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    In stock of ZB MED Cologne/Königswinter

    Ui IV Zs 10: Show issues Location:
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  4. Book ; Online: Hinweise zum Betrieb von Abluftreinigungsanlagen für die Schweinehaltung

    Hahne, Jochen / Arends, Friedrich / Geburek, Frank / Pfeifer, Tommy / Häuser, Sven

    Teil 1: Grundlagen und Verfahrensübersicht

    2023  

    Keywords Text ; ddc:630 ; ddc:333.7
    Language German
    Publisher DLG
    Publishing country de
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Trends of mortality rate in patients with congenital heart defects in Germany-analysis of nationwide data of the Federal Statistical Office of Germany.

    Abdul-Khaliq, Hashim / Gomes, Delphina / Meyer, Sascha / von Kries, Rüdiger / Wagenpfeil, Stefan / Pfeifer, Jochen / Poryo, Martin

    Clinical research in cardiology : official journal of the German Cardiac Society

    2024  Volume 113, Issue 5, Page(s) 750–760

    Abstract: Background: Congenital heart defects (CHD) are still associated with an increased morbidity and mortality. The aim of this study was to analyze trends of mortality rates in patients with CHD between 1998 and 2018 in Germany.: Methods: Data of ... ...

    Abstract Background: Congenital heart defects (CHD) are still associated with an increased morbidity and mortality. The aim of this study was to analyze trends of mortality rates in patients with CHD between 1998 and 2018 in Germany.
    Methods: Data of registered deaths with an underlying diagnosis of CHD were used to evaluate annual mortality between 1998 and 2018. Polynomial regressions were performed to assess annual changes in CHD-associated mortality rates by age groups.
    Results: During the 21-year study period, a total of 11,314 deaths were attributed to CHD with 50.9% of deaths in infants (age < 1 year) and 28.2% in neonates (age ≤ 28 days). The most frequent underlying CHDs associated with death were hypoplastic left heart syndrome (n = 1498, 13.2%), left ventricular outflow tract obstruction (n = 1009, 8.9%), atrial septal defects (n = 771, 6.8%), ventricular septal defects (n = 697, 6.2%), and tetralogy of Fallot (n = 673, 5.9%), and others (n = 6666, 58.9%). Among all patients, annual CHD-related mortality rates declined significantly between 1998 and 2010 (p < 0.0001), followed by a significant annual increase until 2018 (p < 0.0001). However, mortality rates in 2018 in all ages were significantly lower than in 1998.
    Conclusion: Mortality in CHD patients decreased significantly between 1998 and 2010, but a substantial number of deaths still occurred and even significantly increased in the last 3 years of the observation period particularly in neonates and infants. This renewed slight increase in mortality rate during the last years was influenced mainly by high-risk neonates and infants. Assessment of factors influencing the mortality rate trends in association with CHD in Germany is urgently needed. Obligatory nationwide registration of death cases in relation to surgical and catheter interventions in CHD patients is necessary to provide additional valuable data on the outcome of CHD.
    MeSH term(s) Infant ; Infant, Newborn ; Humans ; Heart Defects, Congenital/complications ; Heart Septal Defects, Ventricular/complications ; Heart Septal Defects, Atrial/complications ; Prevalence ; Germany
    Language English
    Publishing date 2024-03-04
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2213295-8
    ISSN 1861-0692 ; 1861-0684
    ISSN (online) 1861-0692
    ISSN 1861-0684
    DOI 10.1007/s00392-023-02370-6
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    In stock of ZB MED Cologne/Königswinter

    Ui IV Zs 10: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  6. Article ; Online: Heat Resistance of Bacillus cereus Spores Located between Seals and Seal Surfaces.

    Pfeifer, Jochen / Kessler, Heinz G

    Journal of food protection

    2019  Volume 58, Issue 11, Page(s) 1206–1210

    Abstract: The heat resistance of Bacillus cereus ATCC 14579 spores enclosed between a silicone-rubber seal and a stainless-steel surface was determined in a temperature range from 90°C to 112°C. Under these conditions spores exhibited a markedly higher resistance ... ...

    Abstract The heat resistance of Bacillus cereus ATCC 14579 spores enclosed between a silicone-rubber seal and a stainless-steel surface was determined in a temperature range from 90°C to 112°C. Under these conditions spores exhibited a markedly higher resistance than in distilled water. Attachment of spores to one of the surfaces had no effect on the heat resistance if the spores were still in direct contact with the heating medium (water or saturated steam). At 90°C suspended spores were killed 1.7 times, at 98°C 2.2 times, at 106°C 14 times, and at 112°C 18 times faster than the enclosed spores. The minor temperature dependence of the heat destruction under the seals resulted in an Arrhenius activation energy of 135 kJ/mol, in comparison with 285 kJ/mol for the suspended spores. It is suggested that the free water initially present is completely replaced by the elastic seal as it is pressed onto the seal surface. The environment of the enclosed spores therefore might be compared to an environment of reduced water activity which is known to bring about a drastic increase in heat resistance.
    Language English
    Publishing date 2019-06-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 243284-5
    ISSN 1944-9097 ; 0362-028X
    ISSN (online) 1944-9097
    ISSN 0362-028X
    DOI 10.4315/0362-028X-58.11.1206
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    In stock of ZB MED Bonn / Germany

    Z 2631: Show issues

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  7. Book ; Online: Hinweise zum Betrieb von Abluftreinigungsanlagen für die Schweinehaltung

    Hahne, Jochen / Arends, Friedrich / Geburek, Frank / Pfeifer, Tommy / Häuser, Sven

    Teil 2: Betriebsdaten und Verbrauchswerte

    2023  

    Abstract: Die DLG hat bereits in den 1980er Jahren Abluftreinigungsanlagen geprüft und zertifiziert. Damals – wie auch heute – mit dem Ziel, die Belange der Genehmigungsbehörden, der Landwirtinnen und Landwirte sowie der Hersteller gleichermaßen zu berücksichtigen. ...

    Abstract Die DLG hat bereits in den 1980er Jahren Abluftreinigungsanlagen geprüft und zertifiziert. Damals – wie auch heute – mit dem Ziel, die Belange der Genehmigungsbehörden, der Landwirtinnen und Landwirte sowie der Hersteller gleichermaßen zu berücksichtigen. Eine unabhängige Kommission prüft Anlagen nach deren Wirkungsgrad, Arbeitssicherheit, Handhabung und Funktion im praktischen Einsatz. Die im Prüfrahmen enthaltenen Grenzwerte für die Reinigungsleistung wurden festgesetzt, um den Belangen der zu schützenden Umwelt gerecht zu werden. Funktionierende Filteranlagen ermöglichen in vielen Regionen erst die Erweiterung bestehender oder den Bau neuer Stallanlagen, wenn alle anderen Maßnahmen zur Emissionsminderung im Stall ausgereizt sind. Das vorliegende Merkblatt ist der zweite Teil der Reihe „Hinweise um Betrieb von Abluftreinigungsanlagen für die Schweinehaltung“ und gibt wertvolle Hinweise zur Reduzierung der Betriebskosten. Die beispielhaften Betriebsdaten und Verbrauchswerte zertifizierter Anlagen aus der DLG-Prüfung ergänzen diese Hinweise. Abluftreinigungsanlagen müssen zu dem jeweiligen Stall und den örtlichen Gegebenheiten passen. Die Hilfestellungen und Informationen der beiden Merkblätter 483 und 484 sollen Betriebsleiterinnen und Betriebsleiter bei der Entscheidung für das richtige System unterstützen. Auch anderen Beteiligten eines Genehmigungsverfahrens sollen mit den beiden Merkblättern die Möglichkeiten und Grenzen von Abluftreinigungsanlagen in der Schweinehaltung aufgezeigt werden.
    Keywords Text ; ddc:630 ; ddc:333.7
    Subject code 710
    Language German
    Publisher DLG
    Publishing country de
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Book ; Thesis: German community pharmacists

    Pfeifer, Jochen

    from product-oriented suppliers to patient-oriented health care professionals

    2015  

    Title variant Advancing the professionalization of German community pharmacists and creating a new mission statement unsing select international best practice standards
    Author's details Jochen Pfeifer
    Keywords Pharmahandel ; Berufsbildung ; Anforderungsprofil ; Macht ; Deutschland ; USA
    Language English
    Size 146 S., graph. Darst.
    Edition 2., unrev. ed.
    Publisher Nomos-Verl.-Ges
    Publishing place Baden-Baden
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Univ., Diss. u.d.T.: Pfeifer, Jochen: Advancing the professionalization of German community pharmacists and creating a new mission statement unsing select international best practice standards--Bremen, 2014
    ISBN 9783845260877 ; 9783848717408 ; 3845260874 ; 3848717409
    Database ECONomics Information System

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  9. Book ; Thesis: German community pharmacists

    Pfeifer, Jochen

    from product-oriented suppliers to patient-oriented health care professionals

    2015  

    Title variant Advancing the professionalization of German community pharmacists and creating a new mission statement unsing select international best practice standards
    Author's details Jochen Pfeifer
    Keywords Pharmahandel ; Berufsbildung ; Anforderungsprofil ; Macht ; Deutschland ; USA
    Language English
    Size 146 S., graph. Darst.
    Edition 2., unrev. ed.
    Publisher Nomos-Verl.-Ges
    Publishing place Baden-Baden
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Univ., Diss. u.d.T.: Pfeifer, Jochen: Advancing the professionalization of German community pharmacists and creating a new mission statement unsing select international best practice standards--Bremen, 2014
    ISBN 9783845260877 ; 9783848717408 ; 3845260874 ; 3848717409
    Database Former special subject collection: coastal and deep sea fishing

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  10. Book: German Community Pharmacists

    Pfeifer, Jochen

    From Product-Oriented Suppliers to Patient-Oriented Health Care Professionals

    2014  

    Author's details Jochen Pfeifer
    Keywords Apotheke ; Arzneiverordnung ; Arzneimitteldosis ; Kosten-Nutzen-Kalkulation ; Patienteninformation ; Pharmahandel ; Qualifikation ; Dienstleistungsqualität ; Beziehungsmarketing ; Patienten ; Deutschland ; Benchmarking ; USA
    Language English
    Size 146 S
    Edition 1. Aufl
    Publisher Nomos
    Publishing place Baden-Baden
    Document type Book
    ISBN 3848715228 ; 9783848715220
    Database ECONomics Information System

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