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  1. Article ; Online: Autoantibody Response to ZRF1 and KRR1 SEREX Antigens in Patients with Breast Tumors of Different Histological Types and Grades.

    Dyachenko, Lada / Havrysh, Kristina / Lytovchenko, Anita / Dosenko, Irina / Antoniuk, Stepan / Filonenko, Valeriy / Kiyamova, Ramziya

    Disease markers

    2016  Volume 2016, Page(s) 5128720

    Abstract: ... ...

    Abstract Purpose
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Antigens, Neoplasm/blood ; Antigens, Neoplasm/genetics ; Antigens, Neoplasm/immunology ; Autoantibodies/blood ; Base Sequence ; Biomarkers, Tumor/blood ; Biomarkers, Tumor/immunology ; Breast Neoplasms/blood ; Breast Neoplasms/immunology ; Breast Neoplasms/pathology ; Carcinoma, Ductal, Breast/blood ; Carcinoma, Ductal, Breast/immunology ; Carcinoma, Ductal, Breast/pathology ; Carcinoma, Lobular/blood ; Carcinoma, Lobular/immunology ; Carcinoma, Lobular/pathology ; Carcinoma, Medullary/blood ; Carcinoma, Medullary/immunology ; Carcinoma, Medullary/pathology ; Case-Control Studies ; DNA-Binding Proteins/blood ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/immunology ; Enzyme-Linked Immunosorbent Assay ; Female ; Follow-Up Studies ; Gene Library ; Humans ; Middle Aged ; Molecular Chaperones ; Neoplasm Grading ; Neoplasm Staging ; Nuclear Pore Complex Proteins/blood ; Nuclear Pore Complex Proteins/genetics ; Nuclear Pore Complex Proteins/immunology ; Oncogene Proteins/blood ; Oncogene Proteins/genetics ; Oncogene Proteins/immunology ; Prognosis ; RNA-Binding Proteins/blood ; RNA-Binding Proteins/genetics ; RNA-Binding Proteins/immunology ; Young Adult
    Chemical Substances AGFG1 protein, human ; Antigens, Neoplasm ; Autoantibodies ; Biomarkers, Tumor ; DNA-Binding Proteins ; DNAJC2 protein, human ; Molecular Chaperones ; Nuclear Pore Complex Proteins ; Oncogene Proteins ; RNA-Binding Proteins
    Language English
    Publishing date 2016-10-25
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 604951-5
    ISSN 1875-8630 ; 0278-0240
    ISSN (online) 1875-8630
    ISSN 0278-0240
    DOI 10.1155/2016/5128720
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Autoantibody Response to ZRF1 and KRR1 SEREX Antigens in Patients with Breast Tumors of Different Histological Types and Grades

    Lada Dyachenko / Kristina Havrysh / Anita Lytovchenko / Irina Dosenko / Stepan Antoniuk / Valeriy Filonenko / Ramziya Kiyamova

    Disease Markers, Vol

    2016  Volume 2016

    Abstract: Purpose. To investigate a frequency of antibody response to SEREX-identified medullary breast carcinoma autoantigens ZRF1 and KRR1 in sera of breast cancer patients taking into account clinical and molecular characteristics of tumors for opening of new ... ...

    Abstract Purpose. To investigate a frequency of antibody response to SEREX-identified medullary breast carcinoma autoantigens ZRF1 and KRR1 in sera of breast cancer patients taking into account clinical and molecular characteristics of tumors for opening of new perspectives in creation of minimally invasive immunological tests for cancer diagnostics. Methods. Enzyme-linked immunosorbent assay and bioinformatics analysis. Results. Increased frequency of antibody response was found in sera of breast cancer patients to ZRF and KRR1 antigens. The antibody response to these antigens was higher in sera of patients with invasive ductal carcinoma than in sera of patients with other histological types of breast tumors. Moreover, more frequent antibody response to ZRF antigen was found in sera of patients with less aggressive tumors. The sequence analysis of ZRF1 antigen SEREX clones obtained from cDNA libraries of different tumors demonstrates that they encode different protein isoforms. Conclusion. Tumor-associated antigens KRR1 and ZRF1 and their cognate autoantibodies could be considered as potential molecular markers of breast cancer which need to be further investigated.
    Keywords Medicine (General) ; R5-920
    Subject code 616 ; 610
    Language English
    Publishing date 2016-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: [No title information]

    Matveeva, Maria D. / Borisova, Tatiana N. / Titov, Alexander A. / Anikina, Lada V. / Dyachenko, Svetlana V. / Astakhov, Grigorii S. / Varlamov, Alexey V. / Voskressensky, Leonid G.

    Synthesis

    2017  Volume 49, Issue 23, Page(s) 5251–5257

    Abstract: An efficient synthesis of pyrrolo[2,1- a ]isoquinolines by a domino reaction from a variety of 3,4-dihydropyrrolo[2,1- a ]isoquinolines and α,β-unsaturated aldehydes in the absence of catalyst in good yields under microwave irradiation, is reported. ...

    Abstract An efficient synthesis of pyrrolo[2,1- a ]isoquinolines by a domino reaction from a variety of 3,4-dihydropyrrolo[2,1- a ]isoquinolines and α,β-unsaturated aldehydes in the absence of catalyst in good yields under microwave irradiation, is reported.
    Keywords domino reaction ; dihydroisoquinolines ; aldehydes ; microwave irradiation ; cytotoxic activity
    Language English
    Publishing date 2017-08-22
    Publisher © Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2033062-5
    ISSN 1437-210X ; 0039-7881
    ISSN (online) 1437-210X
    ISSN 0039-7881
    DOI 10.1055/s-0036-1588486
    Database Thieme publisher's database

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