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  1. Book: Decellularization methods of tissue and whole organ in tissue engineering

    Kajbafzadeh, Abdol-Mohammad

    (Advances in experimental medicine and biology ; 1345)

    2021  

    Author's details Abdol-Mohammad Kajbafzadeh editor
    Series title Advances in experimental medicine and biology ; 1345
    Collection
    Language English
    Size xiii, 259 Seiten, Illustrationen
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT021110550
    ISBN 978-3-030-82734-2 ; 9783030827359 ; 3-030-82734-8 ; 3030827356
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: AUTHORS' RESPONSE.

    Kajbafzadeh, Abdol-Mohammad / Kamran, Hooman

    Urology

    2023  Volume 180, Page(s) 241

    Language English
    Publishing date 2023-08-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 192062-5
    ISSN 1527-9995 ; 0090-4295
    ISSN (online) 1527-9995
    ISSN 0090-4295
    DOI 10.1016/j.urology.2023.05.053
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: The Three-Dimensional Structure of Tissues and Organs: A Scanning Electron Microscopic Atlas for Research and Education.

    Sabetkish, Shabnam / Kajbafzadeh, Abdol-Mohammad

    Advances in experimental medicine and biology

    2021  Volume 1345, Page(s) 253–259

    MeSH term(s) Educational Status ; Electrons ; Microscopy, Electron, Scanning
    Language English
    Publishing date 2021-09-28
    Publishing country United States
    Document type Journal Article
    ISSN 2214-8019 ; 0065-2598
    ISSN (online) 2214-8019
    ISSN 0065-2598
    DOI 10.1007/978-3-030-82735-9_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: The Renal Extracellular Matrix as a Supportive Scaffold for Kidney Tissue Engineering: Progress and Future Considerations.

    Sabetkish, Shabnam / Kajbafzadeh, Abdol-Mohammad

    Advances in experimental medicine and biology

    2021  Volume 1345, Page(s) 103–118

    Abstract: During the past decades, diverse methods have been used toward renal tissue engineering in order to replace renal function. The goals of all these techniques included the recapitulation of renal filtration, re-absorptive, and secretary functions, and ... ...

    Abstract During the past decades, diverse methods have been used toward renal tissue engineering in order to replace renal function. The goals of all these techniques included the recapitulation of renal filtration, re-absorptive, and secretary functions, and replacement of endocrine/metabolic activities. It is also imperative to develop a reliable, up scalable, and timely manufacturing process. Decellularization of the kidney with intact ECM is crucial for in-vivo compatibility and targeted clinical application. Contemporarily there is an increasing interest and research in the field of regenerative medicine including stem cell therapy and tissue bioengineering in search for new and reproducible sources of kidneys. In this chapter, we sought to determine the most effective method of renal decellularization and recellularization with emphasis on biologic composition and support of stem cell growth. Current barriers and limitations of bioengineered strategies will be also discussed, and strategies to overcome these are suggested.
    MeSH term(s) Extracellular Matrix ; Kidney/physiology ; Regenerative Medicine ; Tissue Engineering ; Tissue Scaffolds
    Language English
    Publishing date 2021-09-28
    Publishing country United States
    Document type Journal Article
    ISSN 2214-8019 ; 0065-2598
    ISSN (online) 2214-8019
    ISSN 0065-2598
    DOI 10.1007/978-3-030-82735-9_9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: The Most Ideal Pancreas Extracellular Matrix as a Platform for Pancreas Bioengineering: Decellularization/Recellularization Protocols.

    Sabetkish, Shabnam / Kajbafzadeh, Abdol-Mohammad

    Advances in experimental medicine and biology

    2021  Volume 1345, Page(s) 61–70

    Abstract: Natural scaffold appears to have extensive functions in providing anchorage and structural requirements, as well as providing a structural support for cell adherence and cell interaction for further recellularization process. Specific methods used for ... ...

    Abstract Natural scaffold appears to have extensive functions in providing anchorage and structural requirements, as well as providing a structural support for cell adherence and cell interaction for further recellularization process. Specific methods used for decellularization process play an essential role in the efficacy of cell removal and successful preservation of ultrastructure and biomechanical properties of the tissue. Numerous scaffolding materials and fabrication techniques have been investigated for pancreatic tissue engineering. Techniques of casting, freeze drying, injection molding, and electrospinning have been also used to fabricate scaffolds. Herein, we aim to review the state-of-the-art and the tissue engineering and regenerative medicine technology highlighting the major achievements toward the production of a bioengineered pancreas obtained decellularization techniques and cell-on-scaffold technology.
    MeSH term(s) Bioengineering ; Extracellular Matrix ; Pancreas ; Tissue Engineering ; Tissue Scaffolds
    Language English
    Publishing date 2021-09-28
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2214-8019 ; 0065-2598
    ISSN (online) 2214-8019
    ISSN 0065-2598
    DOI 10.1007/978-3-030-82735-9_6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Lung Extracellular Matrix as a Platform for Lung Organ Bioengineering: Design and Development of Tissue Engineered Lung.

    Sabetkish, Shabnam / Kajbafzadeh, Abdol-Mohammad

    Advances in experimental medicine and biology

    2021  Volume 1345, Page(s) 35–46

    Abstract: Since lung tissue is not able to be reconstructed after substantial injury, lung transplantation often is the only alternative for treatment. Antibiotic-resistant organisms that remain in donor lungs causing infection in the immunosuppressed recipient ... ...

    Abstract Since lung tissue is not able to be reconstructed after substantial injury, lung transplantation often is the only alternative for treatment. Antibiotic-resistant organisms that remain in donor lungs causing infection in the immunosuppressed recipient are among the complications following transplantation. Development of strategies for whole lung regeneration is a pleasing choice particularly in patients with end-stage lung diseases. Reconstruction of lung tissue in vitro for transplantation received increased attention which could deal with the shortage of donor organs. Recent advancements in the field of tissue engineering and regenerative medicine have paved the road for beneficial alternative therapies. Our group has extensive experience with regard to the structure of the lung tissue, which makes us to our decision to continue with the preparation of lung, with the aim of developing a new ECM scaffold. Herein, we aim to review the state-of-art and the tissue engineering and regenerative medicine technology highlighting the major achievements toward the production of a bioengineered lung obtained decellularization and recellularization techniques. We have strong hopes that recent developments in the engineering of lung will lead to similar breakthroughs in the engineering of distal lung components in the future.
    MeSH term(s) Bioengineering ; Extracellular Matrix ; Humans ; Lung ; Tissue Engineering ; Tissue Scaffolds
    Language English
    Publishing date 2021-09-28
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2214-8019 ; 0065-2598
    ISSN (online) 2214-8019
    ISSN 0065-2598
    DOI 10.1007/978-3-030-82735-9_4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Correction to: Stem Cells and Natural Agents in the Management of Neurodegenerative Diseases: A New Approach.

    Brockmueller, Aranka / Mahmoudi, Negin / Moaveni, Amir Kian / Mueller, Anna-Lena / Kajbafzadeh, Abdol-Mohammad / Shakibaei, Mehdi / Zolbin, Masoumeh Majidi

    Neurochemical research

    2024  Volume 49, Issue 5, Page(s) 1419

    Language English
    Publishing date 2024-01-06
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 199335-5
    ISSN 1573-6903 ; 0364-3190
    ISSN (online) 1573-6903
    ISSN 0364-3190
    DOI 10.1007/s11064-024-04100-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Does sacral ratio have any impact on success rate of biofeedback therapy in children with lower urinary tract dysfunction?

    Zahir, Mazyar / Sharifi-Rad, Lida / Ladi-Seyedian, Seyedeh-Sanam / Kajbafzadeh, Abdol-Mohammad

    Journal of pediatric urology

    2024  

    Abstract: Introduction: To evaluate the possible impact of patients' sacral ratios (SRs) on response to biofeedback (BF) therapy in pediatric patients with lower urinary tract dysfunction (LUTD).: Materials and methods: In this retrospective cohort conducted ... ...

    Abstract Introduction: To evaluate the possible impact of patients' sacral ratios (SRs) on response to biofeedback (BF) therapy in pediatric patients with lower urinary tract dysfunction (LUTD).
    Materials and methods: In this retrospective cohort conducted from 2016 to 2018 in our tertiary medical center, we included the medical records of all pediatric patients with LUTD who were nominated for BF due to having abnormal uroflowmetry patterns and simultaneous increase in electromyography (EMG) activity. Ten sessions of weekly animated BF were performed for each patient. All patients underwent a complete urological evaluation, uroflowmetry with simultaneous EMG and post-void residual measurement before and after treatment. SRs were calculated based on plain anteroposterior lumbosacral radiographs. Patients were then divided into normal SR (≥0.74) and low SR (<0.74) and outcomes were compared between them.
    Results: Of the total 86 patients included in our study, 48 (55.8%) had a normal SR (≥0.74), while 38 (44.2%) had a low SR (<0.74). Our data revealed that BF therapy significantly improved maximum and average urinary flow rates, urine volume, daytime urinary incontinence, enuresis, urinary urgency and constipation; irrespective of the patients' SRs (all P < 0.001). Our between-groups analyses showed that after the completion of BF, the SR ≥ 0.74 group had significantly higher maximum urinary flow rate (mean difference [95%CI]: 7.7 [5.4, 10.0], P < 0.001) (Figure) and urine volume (mean difference [95%CI]: 49.9 [19.5, 80.4], P = 0.002) and significantly lower diurnal urinary incontinence (4.2% vs. 21.1%, P = 0.020), enuresis (4.2% vs. 18.4%, P = 0.040) and constipation (2.1% vs. 23.7%, P = 0.004) compared to the SR < 0.74 group.
    Discussion: SR has been proposed as a reliable indicator of bony pelvis growth and subsequent lumbosacral neurodevelopment. Additionally, larger SR values are associated with better postoperative sphincter function in children with urological and anorectal malformations. Our results demonstrated that after completion of BF, the normal SR group had a significantly better improvement of some of the uroflowmetry indicators and LUTD-associated symptoms compared to the low SR group.
    Conclusion: Our findings implied that although BF therapy is an efficient treatment for children with LUTD, irrespective of their sacral development; children with enhanced sacral development may benefit from better clinical response, especially in terms of LUTD-associated symptoms.
    Language English
    Publishing date 2024-03-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2237683-5
    ISSN 1873-4898 ; 1477-5131
    ISSN (online) 1873-4898
    ISSN 1477-5131
    DOI 10.1016/j.jpurol.2024.03.025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Whole-Heart Tissue Engineering and Cardiac Patches: Challenges and Promises.

    Akbarzadeh, Aram / Sobhani, Soheila / Soltani Khaboushan, Alireza / Kajbafzadeh, Abdol-Mohammad

    Bioengineering (Basel, Switzerland)

    2023  Volume 10, Issue 1

    Abstract: Despite all the advances in preventing, diagnosing, and treating cardiovascular disorders, they still account for a significant part of mortality and morbidity worldwide. The advent of tissue engineering and regenerative medicine has provided novel ... ...

    Abstract Despite all the advances in preventing, diagnosing, and treating cardiovascular disorders, they still account for a significant part of mortality and morbidity worldwide. The advent of tissue engineering and regenerative medicine has provided novel therapeutic approaches for the treatment of various diseases. Tissue engineering relies on three pillars: scaffolds, stem cells, and growth factors. Gene and cell therapy methods have been introduced as primary approaches to cardiac tissue engineering. Although the application of gene and cell therapy has resulted in improved regeneration of damaged cardiac tissue, further studies are needed to resolve their limitations, enhance their effectiveness, and translate them into the clinical setting. Scaffolds from synthetic, natural, or decellularized sources have provided desirable characteristics for the repair of cardiac tissue. Decellularized scaffolds are widely studied in heart regeneration, either as cell-free constructs or cell-seeded platforms. The application of human- or animal-derived decellularized heart patches has promoted the regeneration of heart tissue through in vivo and in vitro studies. Due to the complexity of cardiac tissue engineering, there is still a long way to go before cardiac patches or decellularized whole-heart scaffolds can be routinely used in clinical practice. This paper aims to review the decellularized whole-heart scaffolds and cardiac patches utilized in the regeneration of damaged cardiac tissue. Moreover, various decellularization methods related to these scaffolds will be discussed.
    Language English
    Publishing date 2023-01-12
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2746191-9
    ISSN 2306-5354
    ISSN 2306-5354
    DOI 10.3390/bioengineering10010106
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Three-dimensional Computed Tomography Scan of the Pelvic Bone in Isolated Epispadias: Analysis Before Surgical Correction.

    Kamran, Hooman / Bitaraf, Masoud / Tanhaeivash, Roozbeh / Kajbafzadeh, Abdol-Mohammad

    Urology

    2023  Volume 180, Page(s) 235–241

    Abstract: Objective: To determine intrapelvic angles and distances in pure epispadias patients and compare them to normal values.: Methods: Using three-dimensional computed tomography, 17 intrapelvic dimensions (8 angles and 9 distances) were measured in 26 ... ...

    Abstract Objective: To determine intrapelvic angles and distances in pure epispadias patients and compare them to normal values.
    Methods: Using three-dimensional computed tomography, 17 intrapelvic dimensions (8 angles and 9 distances) were measured in 26 patients with pure epispadias (21 boys and 5 girls). These values were compared to normal values obtained from 6 patients (5 boys and 1 girl) who underwent either pelvic or abdominopelvic computed tomography for purposes unrelated to their bony pelvis.
    Results: Significant differences were observed in five angles (sacroiliac joint angle, S1 tilt angle, sacral curvature, superior-inferior rotation of the pelvis, and pubococcygeal angle; P-value=.016, .044, .011, .020, and .001, respectively); these show less sacral rotation toward the axial plane, more sacral curvature, inferior rotation of the pelvis, and sacroiliac joints' rotation toward the coronal plane in epispadias compared to controls. Also, two distances (pubic diastasis and anterior segment length of the pelvis; P-value=.002 and .012, respectively) had significant differences, showing wider pubic diastasis and shorter anterior segment in epispadias. However, the differences between other intrapelvic angles and distances were not statistically significant between the two groups.
    Conclusion: In addition to the explanations hypothesized for the embryology of the exstrophy-epispadias complex, there can be other etiologies for both epispadias and bladder exstrophy to explain the differences between bony anatomies of the pelvis in these patients.
    MeSH term(s) Male ; Female ; Humans ; Epispadias/diagnostic imaging ; Epispadias/surgery ; Pelvic Bones/diagnostic imaging ; Tomography, X-Ray Computed/methods ; Bladder Exstrophy/diagnostic imaging ; Bladder Exstrophy/surgery ; Pelvic Floor
    Language English
    Publishing date 2023-07-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 192062-5
    ISSN 1527-9995 ; 0090-4295
    ISSN (online) 1527-9995
    ISSN 0090-4295
    DOI 10.1016/j.urology.2023.05.050
    Database MEDical Literature Analysis and Retrieval System OnLINE

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