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  1. Article ; Online: Recombinant FVIII: the milestone of modern hemophilia treatment.

    Mannucci, Pier Mannuccio

    Haematologica

    2023  Volume 108, Issue 5, Page(s) 1201–1202

    MeSH term(s) Humans ; Hemophilia A ; Factor VIII ; Recombinant Proteins
    Chemical Substances Factor VIII (9001-27-8) ; Recombinant Proteins
    Language English
    Publishing date 2023-05-01
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2333-4
    ISSN 1592-8721 ; 0017-6567 ; 0390-6078
    ISSN (online) 1592-8721
    ISSN 0017-6567 ; 0390-6078
    DOI 10.3324/haematol.2023.282874
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  2. Article ; Online: Health and the environment: messages for the cardiologist.

    Mannucci, Pier Mannuccio

    European journal of preventive cardiology

    2023  Volume 31, Issue 1, Page(s) 128–130

    MeSH term(s) Humans ; Cardiologists ; Cohort Studies ; Parks, Recreational ; Myocardial Infarction ; Air Pollution ; Denmark
    Language English
    Publishing date 2023-11-06
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 2626011-6
    ISSN 2047-4881 ; 2047-4873
    ISSN (online) 2047-4881
    ISSN 2047-4873
    DOI 10.1093/eurjpc/zwad343
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4686: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  3. Article ; Online: Terapia dell’emofilia in Italia: cosa promette un vicino futuro.

    Mannucci, Pier Mannuccio

    Recenti progressi in medicina

    2023  Volume 114, Issue 5, Page(s) 247–249

    Abstract: In Italy have materialized changes pertaining to the striking progress for replacement and non-replacement therapies in patients with hemophilia A and B. This editorial looks at further progress that is expected to occur in Italy as elsewhere with the ... ...

    Title translation Hemophilia therapy in Italy: what the near future promises.
    Abstract In Italy have materialized changes pertaining to the striking progress for replacement and non-replacement therapies in patients with hemophilia A and B. This editorial looks at further progress that is expected to occur in Italy as elsewhere with the approval of two gene therapies for the hemophilias, as well as the forthcoming approval and availability of a new factor VIII product with a very extended plasma half-life that can be administered no more frequently than once weekly.
    MeSH term(s) Humans ; Hemophilia A/therapy ; Hemophilia A/genetics ; Genetic Therapy ; Italy
    Language Italian
    Publishing date 2023-04-28
    Publishing country Italy
    Document type English Abstract ; Journal Article
    ZDB-ID 138266-4
    ISSN 2038-1840 ; 0034-1193
    ISSN (online) 2038-1840
    ISSN 0034-1193
    DOI 10.1701/4032.40071
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Low-dose emicizumab for more equitable access to prophylaxis in resource limited countries.

    Mannucci, Pier Mannuccio / Hermans, Cedric

    Haemophilia : the official journal of the World Federation of Hemophilia

    2024  

    Language English
    Publishing date 2024-02-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 1229713-6
    ISSN 1365-2516 ; 1351-8216 ; 1355-0691
    ISSN (online) 1365-2516
    ISSN 1351-8216 ; 1355-0691
    DOI 10.1111/hae.14968
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 450: Show issues

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  5. Article ; Online: Factor VIII and von Willebrand factor are wavering proteins: the basis for the therapeutic development of desmopressin.

    Mannucci, Pier Mannuccio / Siboni, Simona Maria

    Research and practice in thrombosis and haemostasis

    2024  Volume 8, Issue 2, Page(s) 102369

    Language English
    Publishing date 2024-03-15
    Publishing country United States
    Document type Journal Article
    ISSN 2475-0379
    ISSN (online) 2475-0379
    DOI 10.1016/j.rpth.2024.102369
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Air pollution, cardiovascular disease, and urban greening: an ecological blueprint.

    Mannucci, Pier Mannuccio

    European journal of preventive cardiology

    2023  Volume 30, Issue 15, Page(s) 1608–1611

    Abstract: A number of studies and systematic reviews indicate that exposure to greenness reduces of all-cause, non accidental mortality, particularly from cardiopulmonary and cancer causes. There is also some evidence that green space residence may be associated ... ...

    Abstract A number of studies and systematic reviews indicate that exposure to greenness reduces of all-cause, non accidental mortality, particularly from cardiopulmonary and cancer causes. There is also some evidence that green space residence may be associated with improved pregnancy and birth outcomes, and with better school performances in children. Furthermore, because at least one third of the premature deaths are globally attributable to exposure to air pollution due household agents, particularly in fragile populations living in low-income countries (i.e., children, older and deprived people, pregnant women), that houseplants are an effective and economic mean for cleaning indoor air and thus reducing volatile organic compounds such as formaldehyde, benzene, toluene and others. On the whole more prospective studies are needed to further elucidate the mechanisms linking air pollution, greenness and health outcomes, although the multiple and interacting mechanisms depicted in this article are all biologically plausible.
    MeSH term(s) Pregnancy ; Child ; Humans ; Female ; Air Pollutants/adverse effects ; Particulate Matter ; Cardiovascular Diseases/diagnosis ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/etiology ; Air Pollution/adverse effects ; Prospective Studies ; Environmental Exposure/adverse effects
    Chemical Substances Air Pollutants ; Particulate Matter
    Language English
    Publishing date 2023-04-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 2626011-6
    ISSN 2047-4881 ; 2047-4873
    ISSN (online) 2047-4881
    ISSN 2047-4873
    DOI 10.1093/eurjpc/zwad119
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4686: Show issues Location:
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  7. Article ; Online: Hemophilia treatment innovation: 50 years of progress and more to come.

    Mannucci, Pier Mannuccio

    Journal of thrombosis and haemostasis : JTH

    2023  Volume 21, Issue 3, Page(s) 403–412

    Abstract: With the goal of emphasizing the striking advances that materialized in hemophilia care particularly in the last 10 years, the progress of knowledge that started from the 1970s will first be sketched as background. Subsequently, the unmet needs ... ...

    Abstract With the goal of emphasizing the striking advances that materialized in hemophilia care particularly in the last 10 years, the progress of knowledge that started from the 1970s will first be sketched as background. Subsequently, the unmet needs pertaining to therapeutic adherence and thus to prophylaxis effectiveness led to the availability of factor VIII and IX products with an extended plasma half-life as well as to emicizumab, the first nonfactor medicine for subcutaneous administration in patients with hemophilia A with or without inhibitor. The issue of a still lacking cure for the disease is approached by means of gene therapy, the first products of which were approved in 2022 for adults with both hemophilia types. Finally, views will be offered on further progress that is expected in the next few years and how patients and their care providers may make personalized choices among the wide array of therapeutic options.
    MeSH term(s) Adult ; Humans ; Hemophilia A ; Genetic Therapy ; Half-Life ; Hemostatics ; Plasma
    Chemical Substances Hemostatics
    Language English
    Publishing date 2023-03-01
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2112661-6
    ISSN 1538-7836 ; 1538-7933
    ISSN (online) 1538-7836
    ISSN 1538-7933
    DOI 10.1016/j.jtha.2022.12.029
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5805: Show issues Location:
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    Zs.MO 295: Show issues

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  8. Book: 30 years of research and innovation with recombinant activated factor VII (eptacog alfa activated)

    Mannucci, Pier M.

    (Blood reviews ; 29, Suppl. 1)

    2015  

    Title variant Thirty years of research and innovation with recombinant activated factor VII (eptacog alfa activated)
    Author's details guest ed.: Pier Mannuccio Mannucci
    Series title Blood reviews ; 29, Suppl. 1
    Collection
    Language English
    Size S41S. : graph. Darst.
    Publisher Elsevier
    Publishing place Amsterdam u.a.
    Publishing country Netherlands
    Document type Book
    HBZ-ID HT018766652
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    Zs A 2207 -29,Suppl.1- not available for loan Zeitschriften-Lesesaal

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  9. Article ; Online: Thrombotic thrombocytopenic purpura and other immune-mediated blood disorders following vaccination against SARS-CoV-2.

    Mannucci, Pier Mannuccio

    Haematologica

    2022  Volume 107, Issue 4, Page(s) 785–786

    MeSH term(s) COVID-19/prevention & control ; Hematologic Diseases ; Humans ; Purpura, Thrombotic Thrombocytopenic/etiology ; SARS-CoV-2 ; Vaccination/adverse effects
    Language English
    Publishing date 2022-04-01
    Publishing country Italy
    Document type Journal Article ; Comment
    ZDB-ID 2333-4
    ISSN 1592-8721 ; 0017-6567 ; 0390-6078
    ISSN (online) 1592-8721
    ISSN 0017-6567 ; 0390-6078
    DOI 10.3324/haematol.2021.279649
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Thrombotic thrombocytopenic purpura and other immune mediated blood disorders following SARS-CoV-2 vaccination.

    Mannucci, Pier Mannuccio

    Haematologica

    2021  

    Abstract: Not available. ...

    Abstract Not available.
    Language English
    Publishing date 2021-08-12
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2333-4
    ISSN 1592-8721 ; 0017-6567 ; 0390-6078
    ISSN (online) 1592-8721
    ISSN 0017-6567 ; 0390-6078
    DOI 10.3324/haematol.2021.279649
    Database MEDical Literature Analysis and Retrieval System OnLINE

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