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  1. Article ; Online: Chinese expert consensus on sedation and analgesia for neurocritical care patients.

    Zhang, Linlin / Liu, Shuai / Wang, Shuya / Zhou, Jianxin

    Chinese medical journal

    2024  

    Language English
    Publishing date 2024-04-19
    Publishing country China
    Document type Journal Article
    ZDB-ID 127089-8
    ISSN 2542-5641 ; 0366-6999 ; 1002-0187
    ISSN (online) 2542-5641
    ISSN 0366-6999 ; 1002-0187
    DOI 10.1097/CM9.0000000000003084
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  2. Article ; Online: Chromosome-level genome assembly of marine diatom Skeletonema tropicum.

    Liu, Shuya / Chen, Nansheng

    Scientific data

    2024  Volume 11, Issue 1, Page(s) 403

    Abstract: Skeletonema tropicum is a marine diatom of the genus Skeletonema that also includes many well-known species including S. marinoi. S. tropicum is a high temperature preferring species thriving in tropical ocean regions or temperate ocean regions during ... ...

    Abstract Skeletonema tropicum is a marine diatom of the genus Skeletonema that also includes many well-known species including S. marinoi. S. tropicum is a high temperature preferring species thriving in tropical ocean regions or temperate ocean regions during summer-autumn. However, mechanisms of ecological adaptation of S. tropicum remain poorly understood due partially to the lack of a high-quality whole genome assembly. Here, we report the first high-quality chromosome-scale genome assembly for S. tropicum, using cutting-edge technologies including PacBio single molecular sequencing and high-throughput chromatin conformation capture. The assembled genome has a size of 78.78 Mb with a scaffold N50 of 3.17 Mb, anchored to 23 pseudo-chromosomes. In total, 20,613 protein-coding genes were predicted, of which 17,757 (86.14%) genes were functionally annotated. Collinearity analysis of the genomes of S. tropicum and S. marinoi revealed that these two genomes were highly homologous. This chromosome-level genome assembly of S. tropicum provides a valuable genomic platform for comparative analysis of mechanisms of ecological adaption.
    MeSH term(s) Chromatin ; Chromosomes ; Diatoms/genetics ; Genome ; Genomics ; Phylogeny
    Chemical Substances Chromatin
    Language English
    Publishing date 2024-04-20
    Publishing country England
    Document type Dataset ; Journal Article
    ZDB-ID 2775191-0
    ISSN 2052-4463 ; 2052-4463
    ISSN (online) 2052-4463
    ISSN 2052-4463
    DOI 10.1038/s41597-024-03238-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Rich diversity and active spatial-temporal dynamics of

    Liu, Kuiyan / Liu, Shuya / Cui, Zongmei / Zhao, Yongfang / Chen, Nansheng

    ISME communications

    2024  Volume 4, Issue 1, Page(s) ycad009

    Abstract: ... ...

    Abstract Thalassiosira
    Language English
    Publishing date 2024-01-10
    Publishing country England
    Document type Journal Article
    ISSN 2730-6151
    ISSN (online) 2730-6151
    DOI 10.1093/ismeco/ycad009
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  4. Article ; Online: Erratum: In Vivo Calcium Imaging of Dorsal Root Ganglia Neurons' Response to Somatic and Visceral Stimuli.

    Liu, Kun / Liu, Yun / Li, Xia / Wang, Shuya / Wang, Xiaoxi / Zhang, Zhiyun / Gao, Xinyan

    Journal of visualized experiments : JoVE

    2024  , Issue 206

    Abstract: This corrects the article 10.3791/65975. ...

    Abstract This corrects the article 10.3791/65975.
    Language English
    Publishing date 2024-04-01
    Publishing country United States
    Document type Journal Article ; Video-Audio Media
    ZDB-ID 2259946-0
    ISSN 1940-087X ; 1940-087X
    ISSN (online) 1940-087X
    ISSN 1940-087X
    DOI 10.3791/6596
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  5. Article: Genomic identification of cotton

    Shuya, Ma / Le, Liu / Huiyun, Shi / Yu, Gu / Yujun, Li / Qanmber, Ghulam

    Frontiers in plant science

    2023  Volume 14, Page(s) 1123745

    Abstract: ... ...

    Abstract SAC
    Language English
    Publishing date 2023-02-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2023.1123745
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  6. Article ; Online: 3-Phosphoinositide-Dependent Kinase 1 as a Therapeutic Target for Treating Diabetes.

    Xiang, Xie / Shuya, Pan / Jiamin, Zhang / Zihan, Zhang / Xumei, Yang / Jingjin, Liu

    Current diabetes reviews

    2024  

    Abstract: The role of 3-phosphoinositide-dependent kinase 1 (PDK1) has been welldocumented in the development of diabetes. This review offers a thorough examination of its composition and associated routes, specifically focusing on insulin signaling and glucose ... ...

    Abstract The role of 3-phosphoinositide-dependent kinase 1 (PDK1) has been welldocumented in the development of diabetes. This review offers a thorough examination of its composition and associated routes, specifically focusing on insulin signaling and glucose processing. By examining the precise connection between PDK1 and diabetes, various strategies specifically targeting PDK1 were also investigated. Additionally, recent discoveries from mouse models were compiled where PDK1 was knocked out in certain tissues, which demonstrated encouraging outcomes for focused treatments despite the absence of any currently approved clinical PDK1 activators. Moreover, the dual nature of PDK1 activation was discussed, encompassing both anti-diabetic and pro-oncogenic effects. Hence, the development of a PDK1 modifier is of utmost importance, as it can activate anti-diabetic pathways while inhibiting pro-oncogenic pathways, thus aiding in the treatment of diabetes. In general, PDK1 presents a noteworthy opportunity for future therapeutic strategies in the treatment of diabetes.
    Language English
    Publishing date 2024-03-11
    Publishing country United Arab Emirates
    Document type Journal Article
    ISSN 1875-6417
    ISSN (online) 1875-6417
    DOI 10.2174/0115733998278669240226061329
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  7. Article: Study on Magnetic and Plasmonic Properties of Fe

    Ning, Shuya / Wang, Shuo / Liu, Zhihui / Zhang, Naming / Yang, Bin / Zhang, Fanghui

    Materials (Basel, Switzerland)

    2024  Volume 17, Issue 2

    Abstract: Magnetic-plasmonic nanoparticles (NPs) have attracted great interest in many fields because they can exhibit more physical and chemical properties than individual magnetic or plasmonic NPs. In this work, we synthesized Au- or Ag-decorated ... ...

    Abstract Magnetic-plasmonic nanoparticles (NPs) have attracted great interest in many fields because they can exhibit more physical and chemical properties than individual magnetic or plasmonic NPs. In this work, we synthesized Au- or Ag-decorated Fe
    Language English
    Publishing date 2024-01-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma17020509
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  8. Article ; Online: Remarkable emission enhancement of CsPbBr

    Ning, Shuya / Liu, Zhihui / Wang, Shuo / Zhang, Naming / Yang, Bin / Wang, Xin / Zhang, Fanghui

    Optics express

    2024  Volume 32, Issue 6, Page(s) 9276–9286

    Abstract: All-inorganic halide perovskite quantum dots (QDs) have recently received much attention due to their excellent optoelectronic properties. And their emission properties still need to be improved for further applications. Here, we demonstrated a ... ...

    Abstract All-inorganic halide perovskite quantum dots (QDs) have recently received much attention due to their excellent optoelectronic properties. And their emission properties still need to be improved for further applications. Here, we demonstrated a remarkable emission enhancement of the CsPbBr
    Language English
    Publishing date 2024-04-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.515772
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  9. Article ; Online: Smart Nanocarriers for the Treatment of Retinal Diseases.

    Liu, Shuya / Yan, Zhike / Huang, Zixiang / Yang, Huanghao / Li, Jingying

    ACS applied bio materials

    2024  Volume 7, Issue 4, Page(s) 2070–2085

    Abstract: Retinal diseases, such as age-related macular degeneration, diabetic retinopathy, and retinoblastoma, stand as the leading causes of irreversible vision impairment and blindness worldwide. Effectively administering drugs for retinal diseases poses a ... ...

    Abstract Retinal diseases, such as age-related macular degeneration, diabetic retinopathy, and retinoblastoma, stand as the leading causes of irreversible vision impairment and blindness worldwide. Effectively administering drugs for retinal diseases poses a formidable challenge due to the presence of complex ocular barriers and elimination mechanisms. Over time, various approaches have been developed to fabricate drug delivery systems for improving retinal therapy including virus vectors, lipid nanoparticles, and polymers. However, conventional nanocarriers encounter issues related to the controllability, efficiency, and safety in the retina. Therefore, the development of smart nanocarriers for effective or more invasive long-term treatment remains a desirable goal. Recently, approaches have surfaced for the intelligent design of nanocarriers, leveraging specific responses to external or internal triggers and enabling multiple functions for retinal therapy such as topical administration, prolonged drug release, and site-specific drug delivery. This Review provides an overview of prevalent retinal pathologies and related pharmacotherapies to enhance the understanding of retinal diseases. It also surveys recent developments and strategies employed in the intelligent design of nanocarriers for retinal disease. Finally, the challenges of smart nanocarriers in potential clinical retinal therapeutic applications are discussed to inspire the next generation of smart nanocarriers.
    MeSH term(s) Humans ; Retinal Diseases/drug therapy ; Drug Delivery Systems ; Pharmaceutical Preparations
    Chemical Substances Pharmaceutical Preparations
    Language English
    Publishing date 2024-03-15
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2576-6422
    ISSN (online) 2576-6422
    DOI 10.1021/acsabm.3c01289
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Transcription Factors-Regulated Leaf Senescence

    Jie Cao / Hairong Liu / Shuya Tan / Zhonghai Li

    International Journal of Molecular Sciences, Vol 24, Iss 9245, p

    Current Knowledge, Challenges and Approaches

    2023  Volume 9245

    Abstract: Leaf senescence is a complex biological process regulated at multiple levels, including chromatin remodeling, transcription, post-transcription, translation, and post-translational modifications. Transcription factors (TFs) are crucial regulators of leaf ...

    Abstract Leaf senescence is a complex biological process regulated at multiple levels, including chromatin remodeling, transcription, post-transcription, translation, and post-translational modifications. Transcription factors (TFs) are crucial regulators of leaf senescence, with NAC and WRKY families being the most studied. This review summarizes the progress made in understanding the regulatory roles of these families in leaf senescence in Arabidopsis and various crops such as wheat, maize, sorghum, and rice. Additionally, we review the regulatory functions of other families, such as ERF, bHLH, bZIP, and MYB. Unraveling the mechanisms of leaf senescence regulated by TFs has the potential to improve crop yield and quality through molecular breeding. While significant progress has been made in leaf senescence research in recent years, our understanding of the molecular regulatory mechanisms underlying this process is still incomplete. This review also discusses the challenges and opportunities in leaf senescence research, with suggestions for possible strategies to address them.
    Keywords leaf senescence ; multiple regulation ; transcription factor ; Arabidopsis ; crop ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
    Language English
    Publishing date 2023-05-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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