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  1. Book: Oxford textbook of movement disorders

    Burn, David J.

    (Oxford textbooks in clinical neurology)

    2013  

    Title variant Textbook of movement disorders ; Movement disorders
    Author's details ed. by David J. Burn
    Series title Oxford textbooks in clinical neurology
    Keywords Movement disorders ; Movement disorders / Diagnosis ; Movement disorders / Treatment ; Bewegungsstörung
    Subject Motorische Störung ; Bewegungsschwäche
    Language English
    Size XII, 361 S. : Ill., graph. Darst.
    Edition 1. ed.
    Publisher Oxford Univ. Press
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    Accompanying material Zugang zur Internetausgabe über Code
    HBZ-ID HT017848095
    ISBN 978-0-19-960953-6 ; 978-0-19-960-953- ; 0-19-960-953-5 ; 0-19-960953-5 ; 978-0-19-960-953-6
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Harveian Oration 2019: Prediction and prevention in the genomic era.

    Burn, John

    Clinical medicine (London, England)

    2020  Volume 20, Issue 1, Page(s) 8–20

    MeSH term(s) Genomics ; Humans
    Language English
    Publishing date 2020-01-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 2048646-7
    ISSN 1473-4893 ; 1470-2118
    ISSN (online) 1473-4893
    ISSN 1470-2118
    DOI 10.7861/clinmed.ed.20.1.harv
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Interventions to improve the mental health of women experiencing homelessness: A systematic review of the literature.

    Anderson, Joanna / Trevella, Charlotte / Burn, Anne-Marie

    PloS one

    2024  Volume 19, Issue 4, Page(s) e0297865

    Abstract: Background: Homelessness is a growing public health challenge in the United Kingdom and internationally, with major consequences for physical and mental health. Women represent a particularly vulnerable subgroup of the homeless population, with some ... ...

    Abstract Background: Homelessness is a growing public health challenge in the United Kingdom and internationally, with major consequences for physical and mental health. Women represent a particularly vulnerable subgroup of the homeless population, with some evidence suggesting that they suffer worse mental health outcomes than their male counterparts. Interventions aimed at improving the lives of homeless women have the potential to enhance mental health and reduce the burden of mental illness in this population. This review synthesised the evidence on the effectiveness and acceptability of interventions which aim to improve mental health outcomes in homeless women.
    Methods: Five electronic bibliographic databases: MEDLINE, PsycInfo, CINAHL, ASSIA and EMBASE, were searched. Studies were included if they measured the effectiveness or acceptability of any intervention in improving mental health outcomes in homeless women. Study quality was assessed using the Effective Public Health Practice Project (EPHPP) Quality Assessment Tool. A narrative summary of the study findings in relation to the research questions was produced.
    Results: Thirty-nine studies met inclusion criteria. Overall, there was moderate evidence of the effectiveness of interventions in improving mental health outcomes in homeless women, both immediately post-intervention and at later follow-up. The strongest evidence was for the effectiveness of psychotherapy interventions. There was also evidence that homeless women find interventions aimed at improving mental health outcomes acceptable and helpful.
    Conclusions: Heterogeneity in intervention and study methodology limits the ability to draw definitive conclusions about the extent to which different categories of intervention improve mental health outcomes in homeless women. Future research should focus on lesser-studied intervention categories, subgroups of homeless women and mental health outcomes. More in-depth qualitative research of factors that enhance or diminish the acceptability of mental health interventions to homeless women is also required.
    MeSH term(s) Humans ; Male ; Female ; Mental Health ; Ill-Housed Persons ; Mental Disorders/epidemiology ; Mental Disorders/therapy ; Social Problems ; Psychotherapy
    Language English
    Publishing date 2024-04-03
    Publishing country United States
    Document type Systematic Review ; Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0297865
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Human locomotion over obstacles reveals real-time prediction of energy expenditure for optimized decision-making.

    Daniels, Katherine A J / Burn, J F

    Proceedings. Biological sciences

    2023  Volume 290, Issue 2000, Page(s) 20230200

    Abstract: Despite decades of evidence revealing a multitude of ways in which animals are adapted to minimize the energy cost of locomotion, little is known about how energy expenditure shapes adaptive gait over complex terrain. Here, we show that the principle of ... ...

    Abstract Despite decades of evidence revealing a multitude of ways in which animals are adapted to minimize the energy cost of locomotion, little is known about how energy expenditure shapes adaptive gait over complex terrain. Here, we show that the principle of energy optimality in human locomotion can be generalized to complex task-level locomotor behaviours requiring advance decision-making and anticipatory control. Participants completed a forced-choice locomotor task requiring them to choose between discrete multi-step obstacle negotiation strategies to cross a 'hole' in the ground. By modelling and analysing mechanical energy cost of transport for preferred and non-preferred manoeuvres over a wide range of obstacle dimensions, we showed that strategy selection was predicted by relative energy cost integrated across the complete multi-step task. Vision-based remote sensing was sufficient to select the strategy associated with the lowest prospective energy cost in advance of obstacle encounter, demonstrating the capacity for energetic optimization of locomotor behaviour in the absence of online proprioceptive or chemosensory feedback mechanisms. We highlight the integrative hierarchic optimizations that are required to facilitate energetically efficient locomotion over complex terrain and propose a new behavioural level linking mechanics, remote sensing and cognition that can be leveraged to explore locomotor control and decision-making.
    MeSH term(s) Animals ; Humans ; Prospective Studies ; Cognition ; Energy Metabolism ; Locomotion ; Telemetry
    Language English
    Publishing date 2023-06-14
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 209242-6
    ISSN 1471-2954 ; 0080-4649 ; 0962-8452 ; 0950-1193
    ISSN (online) 1471-2954
    ISSN 0080-4649 ; 0962-8452 ; 0950-1193
    DOI 10.1098/rspb.2023.0200
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The evaluation of health care leadership development programmes: a scoping review of reviews.

    Burn, Emily / Waring, Justin

    Leadership in health services (Bradford, England)

    2022  Volume ahead-of-print, Issue ahead-of-print

    Abstract: Purpose: The purpose of this paper is to report a scoping review of reviews which investigated HLDP evaluations to determine: how the conceptualisation of leadership development programmes (HLDPs), and despite growing calls for robust evaluations of ... ...

    Abstract Purpose: The purpose of this paper is to report a scoping review of reviews which investigated HLDP evaluations to determine: how the conceptualisation of leadership development programmes (HLDPs), and despite growing calls for robust evaluations of their pedagogic design, delivery and effectiveness, there are concerns regarding the quality of data associated with their evaluation. This scoping review of reviews investigated the reporting of HLDP evaluations to determine: how the conceptualisation of leadership underpinning HLDPs influence their evaluation; how the pedagogical approaches within HLDPs influence their evaluation; and the evaluation designs and measures used to assess HLDPs.
    Design/methodology/approach: The scoping review was conducted on reviews of HLDPs. Searches were performed on four databases and on the grey literature. Data were extracted and a narrative synthesis was developed.
    Findings: Thirty-one papers were included in the scoping review of reviews. A great deal of heterogeneity in HLDPs was identified. Evaluations of HLDPs were affected by poor data quality, and there were limitations in the evidence about "what works". Leadership was conceptualised in different ways across HLDPs, and consequently, there was a lack of consistency as to what is being evaluated and the methods used to assess HLDPs.
    Originality/value: This review of reviews summarises the current evidence on the evaluation of HLDPs. Evaluations of HLDPs need to explicitly account for the complexity of health systems, how this complexity impacts on the development and articulation of leadership practice, and how the underlying conceptualisation of leadership and the associated theory of change articulate a set of assumptions about how HLDPs support leaders to affect change within complex systems.
    Language English
    Publishing date 2022-12-06
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2279996-5
    ISSN 1751-1887 ; 1751-1879 ; 1366-0756
    ISSN (online) 1751-1887
    ISSN 1751-1879 ; 1366-0756
    DOI 10.1108/LHS-05-2022-0056
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Gaussian Process Regression Models for Predicting Atomic Energies and Multipole Moments.

    Burn, Matthew J / Popelier, Paul L A

    Journal of chemical theory and computation

    2023  Volume 19, Issue 4, Page(s) 1370–1380

    Abstract: Developing a force field is a difficult task because its design is typically pulled in opposite directions by speed and accuracy. FFLUX breaks this trend by utilizing Gaussian process regression (GPR) to predict, ... ...

    Abstract Developing a force field is a difficult task because its design is typically pulled in opposite directions by speed and accuracy. FFLUX breaks this trend by utilizing Gaussian process regression (GPR) to predict, at
    Language English
    Publishing date 2023-02-09
    Publishing country United States
    Document type Journal Article
    ISSN 1549-9626
    ISSN (online) 1549-9626
    DOI 10.1021/acs.jctc.2c00731
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The impact of community engagement as a public health intervention to support the mental well-being of single mothers and children living under housing insecure conditions - a rapid literature review.

    Joseph, Natasha / Burn, Anne-Marie / Anderson, Joanna

    BMC public health

    2023  Volume 23, Issue 1, Page(s) 1866

    Abstract: Background: In the UK, the population of homelessness and housing insecurity is increasing among families headed by mothers. The unique stressors of housing insecurity and living in accommodations ill-suited to long-term dwellings increase mental ... ...

    Abstract Background: In the UK, the population of homelessness and housing insecurity is increasing among families headed by mothers. The unique stressors of housing insecurity and living in accommodations ill-suited to long-term dwellings increase mental distress for mothers and children. Community engagement interventions present a public health opportunity to alleviate adverse outcomes for vulnerable families.
    Aim: To synthesise and evaluate evidence of the impact of community engagement interventions in supporting the mental well-being of mothers and children living under housing insecure conditions. To synthesise the components of community engagement interventions as a public health intervention in alleviating mental well-being and non-health outcomes of mothers and children living under housing insecurity.
    Methods: A systematic search of five online bibliographic databases (MEDLINE, EMBASE, PsychINFO, Global Health and Child Development & Adolescent Studies) and grey literature (Carrot2) was conducted in May 2022. Primary studies with community engagement components and housing-insecure single-mother families were included. Intervention data was extracted using the TIDieR checklist and a community engagement keywording tool. The studies' quality was critically appraised using the MetaQAT framework.
    Results: Ten studies meeting inclusion criteria were identified, across two countries (USA & UK). Data from the studies reported positive significant effects for health and personal maternal outcomes in addition to higher positive effects for child health outcomes (e.g., decrease in depression symptoms). Interventions targeting social support and self-efficacy demonstrated potential to improve maternal and child outcomes via the maternal-child relationship. Community engagement at the design, delivery and evaluation intervention stages increased the level of community engagement, however there were tentative links to directly improving mental well-being outcomes.
    Conclusion: There is evidence to suggest that community engagement may be applied as an effective intervention in supporting the mental well-being of mothers and children living under housing insecurity. Proposed intervention effectiveness may be achieved via psychosocial pathways such as improved maternal self-efficacy and social support. However, more embedded long-term process evaluations of these interventions are needed to establish maintenance of these observed benefits and to understand to what extent the findings apply to the UK context.
    MeSH term(s) Adolescent ; Female ; Humans ; Housing ; Mental Disorders ; Mental Health ; Mother-Child Relations ; Public Health
    Language English
    Publishing date 2023-09-26
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2041338-5
    ISSN 1471-2458 ; 1471-2458
    ISSN (online) 1471-2458
    ISSN 1471-2458
    DOI 10.1186/s12889-023-16668-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Recognition of clinical genetics in Europe.

    Burn, John

    European journal of human genetics : EJHG

    2017  Volume 25, Issue s2, Page(s) S50

    MeSH term(s) Committee Membership ; Europe ; Genetic Counseling/organization & administration ; Genetic Testing/methods ; Genetics, Medical/history ; Genetics, Medical/manpower ; History, 20th Century ; History, 21st Century ; Humans ; Professional Staff Committees/history ; Professional Staff Committees/organization & administration ; Societies, Scientific/history ; Societies, Scientific/organization & administration
    Language English
    Publishing date 2017-10-30
    Publishing country England
    Document type Historical Article ; Journal Article
    ZDB-ID 1141470-4
    ISSN 1476-5438 ; 1018-4813
    ISSN (online) 1476-5438
    ISSN 1018-4813
    DOI 10.1038/ejhg.2017.156
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The effect of image fractal properties and its interaction with visual discomfort on gait kinematics.

    Burtan, D / Burn, J F / Spehar, B / Leonards, U

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 16581

    Abstract: Exposure to images of urban environments affords higher cognitive processing demands than exposure to images of nature scenes; an effect potentially related to differences in low-level image statistics such as fractals. The aim of the current study was ... ...

    Abstract Exposure to images of urban environments affords higher cognitive processing demands than exposure to images of nature scenes; an effect potentially related to differences in low-level image statistics such as fractals. The aim of the current study was to investigate whether the fractal dimensions of an abstract scene affect cognitive processing demands, using gait kinematics as a measure of cognitive demand. Participants (n = 40) were asked to walk towards different types of synthetic images which were parametrically varied in their fractal dimensions. At the end of each walk, participants rated each image for its visual discomfort (n = 20) or for its likability (n = 20) as potential confounding factors. Fractal dimensions were predictors of walking speed. Moreover, the interaction between fractal dimensions and subjective visual discomfort but not liking predicted velocity. Overall, these data suggest that fractal dimensions indeed contribute to environmentally induced cognitive processing demands.
    MeSH term(s) Humans ; Fractals ; Biomechanical Phenomena ; Gait ; Walking ; Walking Speed
    Language English
    Publishing date 2023-10-03
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-42114-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The Cost of Developing and Implementing an Antepartum Referral Program for Penicillin Allergy Evaluation at a Single Academic Tertiary Care Hospital.

    Burn, Martina S / Xu, Xiao / Kwah, Jason / Liao, Jane / Son, Moeun

    American journal of perinatology

    2024  

    Abstract: Objective:  Approximately 10% of pregnant individuals report a penicillin allergy, yet most are not truly allergic. Allergy verification during pregnancy is safe and recommended; however, many hospitals lack the infrastructure to execute testing. Our ... ...

    Abstract Objective:  Approximately 10% of pregnant individuals report a penicillin allergy, yet most are not truly allergic. Allergy verification during pregnancy is safe and recommended; however, many hospitals lack the infrastructure to execute testing. Our aim was to evaluate the cost of developing and implementing a penicillin allergy referral program for pregnant individuals at an academic institution and to compare costs of care between patients who were referred and not referred through the program.
    Study design:  We conducted an economic analysis of our institution's antepartum penicillin allergy referral program. We prospectively collected detailed resource utilization data and conducted the analysis from the program's perspective, accounting for costs related to program development, allergy verification, antibiotic cost, and delivery hospitalization. Costs were compared between patients who were referred for evaluation versus patients who were not referred using bivariate tests as well as quantile regression adjusting for baseline differences. A sensitivity analysis was performed for allergy testing cost. All cost estimates were inflation adjusted to 2021 U.S. dollars.
    Results:  The startup cost of program development and educational initiatives was $19,920, or $86 per patient. The median allergy evaluation cost was $397 (interquartile range: $303-$663). There was no significant difference in maternal (median: $13,579 vs. $13,999,
    Conclusion:  The cost of developing a penicillin allergy referral program in pregnancy was modest and did not significantly alter short-term cost of care with potential for long-term cost benefit. Verification of a reported penicillin allergy is an integral part of antibiotic stewardship, and the pregnancy period should be utilized as an important opportunity to perform this evaluation.
    Key points: · The cost of developing and implementing an antepartum penicillin allergy referral program is modest.. · Program cost did not significantly alter short-term cost with a potential for long-term cost benefit.. · Penicillin allergy verification is an important part of antibiotic stewardship and should be expanded..
    Language English
    Publishing date 2024-03-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605671-4
    ISSN 1098-8785 ; 0735-1631
    ISSN (online) 1098-8785
    ISSN 0735-1631
    DOI 10.1055/a-2278-9279
    Database MEDical Literature Analysis and Retrieval System OnLINE

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