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  1. Article: Preface to the current status of colorectal cancer surgery.

    Tan, Ker-Kan

    Journal of gastrointestinal oncology

    2020  Volume 10, Issue 6, Page(s) 1162–1163

    Language English
    Publishing date 2020-01-09
    Publishing country China
    Document type Editorial
    ZDB-ID 2594644-4
    ISSN 2219-679X ; 2078-6891
    ISSN (online) 2219-679X
    ISSN 2078-6891
    DOI 10.21037/jgo.2019.11.01
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Increasing colorectal cancer screening uptake-time to consider a more holistic socio-ecological approach.

    Lau, Jerrald / Tan, Ker-Kan

    Journal of gastrointestinal oncology

    2022  Volume 14, Issue 3, Page(s) 1655–1656

    Language English
    Publishing date 2022-12-09
    Publishing country China
    Document type Editorial
    ZDB-ID 2594644-4
    ISSN 2219-679X ; 2078-6891
    ISSN (online) 2219-679X
    ISSN 2078-6891
    DOI 10.21037/jgo-2022-02
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Bubbles in the colon.

    Law, Jia Hao / Soon, Gwyneth Shook Ting / Tan, Ker-Kan

    Frontline gastroenterology

    2022  Volume 14, Issue 1, Page(s) 87

    Language English
    Publishing date 2022-01-24
    Publishing country England
    Document type Case Reports
    ZDB-ID 2521857-8
    ISSN 2041-4137
    ISSN 2041-4137
    DOI 10.1136/flgastro-2022-102086
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: An Unexplained Lost Voice.

    Law, Jia Hao / Thian, Yee Liang / Tan, Ker-Kan

    JAMA otolaryngology-- head & neck surgery

    2022  Volume 148, Issue 4, Page(s) 369–370

    MeSH term(s) Humans ; Voice ; Voice Disorders/etiology
    Language English
    Publishing date 2022-02-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2701825-8
    ISSN 2168-619X ; 2168-6181
    ISSN (online) 2168-619X
    ISSN 2168-6181
    DOI 10.1001/jamaoto.2021.4280
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Differences in Attitudes and Barriers Towards Advance Care Planning Amongst Ischemic Heart Disease Patients: A Cross-Sectional Study.

    Ng, Alyssa / Khoo, Athena Ming-Gui / Lau, Jerrald / Ang, Chermaine / Sim, Hui-Wen / Tan, Ker-Kan

    The American journal of hospice & palliative care

    2024  , Page(s) 10499091241231881

    Abstract: Objectives: Perceptions towards advanced care planning (ACP) amongst individuals with Ischemic Heart Disease before or after a life-threatening Acute Myocardial Infarction event is underexamined and could impact the appropriate timing for ACP advocacy. ... ...

    Abstract Objectives: Perceptions towards advanced care planning (ACP) amongst individuals with Ischemic Heart Disease before or after a life-threatening Acute Myocardial Infarction event is underexamined and could impact the appropriate timing for ACP advocacy. This cross-sectional study assessed awareness and intentions regarding ACP in individuals with Ischemic Heart Disease, both before and after an Acute Myocardial Infarction, and explored the motivating effect of a near-fatal Acute Myocardial Infarction event on its engagement.
    Methods: This study was conducted from 24 August 2021 through 13 March 2023, whereby patients were administered a one-time questionnaire with no follow-up required. Patients with either chronic Ischemic Heart Disease (group A) or a recent Acute Myocardial Infarction event (group B) were recruited from the outpatient National University Heart Centre, Singapore.
    Results: 101 patients (n = 51 for Group A, n = 50 for Group B) were recruited. Mean age (SD) was 59 (10.5) years and 84 were male (83.2%). Between both groups, patients in group B reported significantly higher scores on 'Lack of information' and 'Self-efficacy' domains, and had no ACP awareness nor plans of doing an ACP compared to group A. ACP awareness was the sole significant predictor of intentions of doing an ACP in the final regression model (
    Conclusions: Interestingly, this study suggests that surviving a potentially life-threatening heart condition did not result in higher intention of doing an ACP. Thus, advocacy of ACP in the community should simply start by raising awareness levels widely and may not need to be focused on individuals' state of health.
    Language English
    Publishing date 2024-02-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1074344-3
    ISSN 1938-2715 ; 1049-9091
    ISSN (online) 1938-2715
    ISSN 1049-9091
    DOI 10.1177/10499091241231881
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Insights from an Exploratory Retrospective Cohort Study: Are Face-to-Face Follow-Up Consultations after Colonoscopy a Thing of the Past?

    Lau, Jerrald / Pang, Ning-Qi / Ang, Chermaine / Tan, Ker-Kan

    Digestive diseases (Basel, Switzerland)

    2023  Volume 41, Issue 4, Page(s) 600–603

    Abstract: Background: Colonoscopy is a commonly performed procedure, but most patients will not actually be found with colorectal cancer. Subsequent face-to-face consultations to explain post-colonoscopy findings are common despite the time and cost-saving ... ...

    Abstract Background: Colonoscopy is a commonly performed procedure, but most patients will not actually be found with colorectal cancer. Subsequent face-to-face consultations to explain post-colonoscopy findings are common despite the time and cost-saving benefits of teleconsultation, especially in a post-COVID-19 era. This exploratory retrospective study examined the proportion of post-colonoscopy follow-up consultations that could have been converted to teleconsultation within a tertiary hospital in Singapore.
    Methods: A retrospective cohort of all patients who underwent colonoscopy in the institution from July to September 2019 was identified. All follow-up face-to-face consultations related to the index colonoscopy from the scope date to 6 months post-colonoscopy were traced. Clinical data relevant to the index colonoscopy and these consultations were extracted from electronic medical records.
    Results: The cohort consisted of 859 patients (68.5% male, age range: 18-96 years). Of these, 15 (1.7%) had colorectal cancer, but the majority (n = 643, 74.9%) were scheduled for at least one post-colonoscopy visit - a total of 884 face-to-face clinical visits. The final sample was 682 (77.1%) face-to-face post-colonoscopy visits that did not involve any procedures performed or indicated the need for any subsequent follow-up.
    Conclusion: If such "unnecessary" post-colonoscopy consultations exist within our institution, then similar situations possibly occur elsewhere. As COVID-19 continues to periodically tax healthcare systems worldwide, preservation of resources will remain integral alongside quality standards of routine patient care. There is a need for detailed analyses and modeling to hypothesize potential savings by also considering the start-up and maintenance costs of switching to a teleconsultation-dominated system.
    MeSH term(s) Humans ; Male ; Adolescent ; Young Adult ; Adult ; Middle Aged ; Aged ; Aged, 80 and over ; Female ; Retrospective Studies ; Follow-Up Studies ; COVID-19/epidemiology ; Remote Consultation/methods ; Colonoscopy ; Colorectal Neoplasms
    Language English
    Publishing date 2023-03-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 632798-9
    ISSN 1421-9875 ; 0257-2753
    ISSN (online) 1421-9875
    ISSN 0257-2753
    DOI 10.1159/000530165
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Health-related quality of life thresholds of clinical importance at diagnosis can predict longitudinal post-operative health functioning in colorectal cancer patients: A prospective multicentre observational study.

    Lau, Jerrald / Khoo, Athena Ming-Gui / Luo, Nan / Tan, Ker-Kan

    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

    2023  Volume 50, Issue 1, Page(s) 107291

    Abstract: Background: Health-related quality of life (HRQOL) is an increasingly important outcome in colorectal cancer (CRC) treatment. Established thresholds for clinical importance (TCI) permit an absolute interpretation of HRQOL scores but less emphasis has ... ...

    Abstract Background: Health-related quality of life (HRQOL) is an increasingly important outcome in colorectal cancer (CRC) treatment. Established thresholds for clinical importance (TCI) permit an absolute interpretation of HRQOL scores but less emphasis has been placed on whether these can be used in a predictive manner. This study aimed to examine if patients' baseline HRQOL functioning scores, subgrouped based on TCI, would significantly predict HRQOL over time.
    Methods: 211 CRC patients were prospectively followed up from diagnosis to 18 months after surgery. Patients were administered the EORTC Core Quality of Life Questionnaire (EORTC QLQ-C30) at each timepoint. Baseline demographic and clinical data were extracted from electronic medical records.
    Results: Only the physical and emotional functioning scales of the EORTC QLQ-C30 were utilised with their respective TCIs (score of ≤83 for physical; ≤71 for emotional). Physical functioning was below-threshold for most patients at pre-discharge (81.77 %) and 1-month (56.48 %) before stabilising to baseline proportions by 6-month. For emotional functioning, 22.04 %-30.98 % of patients were below-threshold between baseline to 3-month, stabilising to approximately 14.00 % after 6-month. Baseline TCI subgrouping was significantly associated with change in HRQOL scores over time for both the physical (β = 14.09, 95 % CI: 8.22, 19.97) and emotional (β = 25.66, 95 % CI: 18.79, 32.53) functioning scales (p < 0.01).
    Conclusion: EORTC QLQ-C30 TCIs can be utilised not just to concretely identify clinically significant impairments in presenting CRC patients, but also as potential predictive tools towards more value-driven delivery of pre- and post-surgical supportive and allied healthcare.
    MeSH term(s) Humans ; Quality of Life/psychology ; Prospective Studies ; Clinical Relevance ; Surveys and Questionnaires ; Colorectal Neoplasms/surgery
    Language English
    Publishing date 2023-12-01
    Publishing country England
    Document type Observational Study ; Multicenter Study ; Journal Article
    ZDB-ID 632519-1
    ISSN 1532-2157 ; 0748-7983
    ISSN (online) 1532-2157
    ISSN 0748-7983
    DOI 10.1016/j.ejso.2023.107291
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Complete mesocolic excision for colon cancer: is it worth it?

    Koh, Frederick H / Tan, Ker-Kan

    Journal of gastrointestinal oncology

    2020  Volume 10, Issue 6, Page(s) 1215–1221

    Abstract: Total mesorectal excision (TME) has been the miracle surgical technique which has since allowed the outcomes of rectal cancer to surpass that of colon cancer. Complete mesocolic excision (CME) attempts to adopt the same principles as that of TME and ... ...

    Abstract Total mesorectal excision (TME) has been the miracle surgical technique which has since allowed the outcomes of rectal cancer to surpass that of colon cancer. Complete mesocolic excision (CME) attempts to adopt the same principles as that of TME and apply it to colon cancer surgery. Initial retrospective case series and comparative studies have shown promising oncological outcomes. CME entails the
    Language English
    Publishing date 2020-01-09
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 2594644-4
    ISSN 2219-679X ; 2078-6891
    ISSN (online) 2219-679X
    ISSN 2078-6891
    DOI 10.21037/jgo.2019.05.01
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Cessation of cancer screening: An unseen cost of the COVID-19 pandemic?

    Tan, Ker-Kan / Lau, Jerrald

    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

    2020  Volume 46, Issue 11, Page(s) 2154–2155

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Early Detection of Cancer ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-11
    Publishing country England
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 632519-1
    ISSN 1532-2157 ; 0748-7983
    ISSN (online) 1532-2157
    ISSN 0748-7983
    DOI 10.1016/j.ejso.2020.05.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Endoscopic stenting in colorectal cancer.

    Lim, Tian-Zhi / Tan, Ker-Kan

    Journal of gastrointestinal oncology

    2020  Volume 10, Issue 6, Page(s) 1171–1182

    Abstract: Acute malignant large bowel obstruction presents as one of the few emergencies of colorectal cancer (CRC). Management of this condition can either be by (I) upfront surgery or (II) the use of self-expanding metallic stent (SEMS) as a bridge to elective ... ...

    Abstract Acute malignant large bowel obstruction presents as one of the few emergencies of colorectal cancer (CRC). Management of this condition can either be by (I) upfront surgery or (II) the use of self-expanding metallic stent (SEMS) as a bridge to elective surgery. For patients with metastasis, the use of SEMS is reported to enable earlier commencement of chemotherapy. Although the use of SEMS in patients with acute malignant large bowel obstruction looks promising, it is plagued by its own set of complications and divided opinion over its long-term outcomes. Conflicting data are present, and definitive indication requires further evaluation and debate. This article will describe the typical presentation of patients with acute malignant large bowel obstruction. An introduction to the SEMS insertion procedural steps will be undertaken. Following which the article aims to review the safety profile of SEMS and the short- and long-term outcomes of SEMS in both the curative and palliative setting.
    Language English
    Publishing date 2020-01-09
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 2594644-4
    ISSN 2219-679X ; 2078-6891
    ISSN (online) 2219-679X
    ISSN 2078-6891
    DOI 10.21037/jgo.2019.02.15
    Database MEDical Literature Analysis and Retrieval System OnLINE

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