Article: Metastatic small cell lung cancer presenting as acute appendicitis: a case report.
Journal of surgical case reports
2023 Volume 2023, Issue 3, Page(s) rjad101
Abstract: We present a case of extensive stage small cell lung cancer presenting as perforated appendicitis secondary to an appendiceal metastasis. This is a rare presentation with only six reported cases in the literature. Surgeons must be aware of unusual causes ...
| Abstract | We present a case of extensive stage small cell lung cancer presenting as perforated appendicitis secondary to an appendiceal metastasis. This is a rare presentation with only six reported cases in the literature. Surgeons must be aware of unusual causes for perforated appendicitis as in our case the prognosis can be dire. A 60-year-old man presented with an acute abdomen and septic shock. Urgent laparotomy and a subtotal colectomy were performed. Further imaging suggested the malignancy was secondary to a primary lung cancer. Histopathology demonstrated a ruptured small cell neuroendocrine carcinoma in the appendix with thyroid transcription factor 1 positive immunohistochemistry. Unfortunately, the patient deteriorated due to respiratory compromise and was palliated day six postoperatively. Surgeons should consider a broad differential diagnosis for the cause of acute perforated appendicitis as this can rarely be due to a secondary metastatic deposit from a widespread malignant process. |
|---|---|
| Language | English |
| Publishing date | 2023-03-07 |
| Publishing country | England |
| Document type | Case Reports |
| ZDB-ID | 2580919-2 |
| ISSN | 2042-8812 |
| ISSN | 2042-8812 |
| DOI | 10.1093/jscr/rjad101 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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