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  1. Article: Ischemic Stroke Revascularization.

    Otani, Naoki / Yoshino, Atsuo

    Advances and technical standards in neurosurgery

    2022  Volume 44, Page(s) 79–96

    Abstract: Extracranial-intracranial (EC-IC) bypass is one of the most fundamental techniques for ischemic cerebrovascular disease (CVD). We describe the standard surgical strategies, advanced techniques, and controversies concerning revascularization of ischemic ... ...

    Abstract Extracranial-intracranial (EC-IC) bypass is one of the most fundamental techniques for ischemic cerebrovascular disease (CVD). We describe the standard surgical strategies, advanced techniques, and controversies concerning revascularization of ischemic stroke. The standard surgical strategies and techniques emphasize how to determine surgical indication, which should be decided for symptomatic internal carotid artery or middle cerebral artery (MCA) occlusive disease with misery perfusion detected by quantitative single photon emission computed tomography. Advanced techniques are available for complex situations such as posterior circulation revascularization, Bonnet bypass for common carotid artery obstruction, and various EC-IC bypasses for ischemia in the MCA and/or anterior cerebral artery territories using inter-grafts such as femoral veins and radial arteries, illustrated by our surgical results and experiences. Controversies include endovascular treatment complementary to EC-IC bypass. Finally, we advocate emergent EC-IC bypass for progressive ischemic CVD, particularly for contraindication or unsuccessful treatment after intravenous tissue plasminogen activator administration and/or endovascular thrombolysis. EC-IC bypass surgery can be reliable for ischemic CVD under strict optimal surgical indications using safe and reliable surgical techniques.
    MeSH term(s) Brain Ischemia/surgery ; Cerebral Revascularization ; Humans ; Ischemic Stroke ; Stroke/diagnostic imaging ; Tissue Plasminogen Activator/therapeutic use
    Chemical Substances Tissue Plasminogen Activator (EC 3.4.21.68)
    Language English
    Publishing date 2022-02-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 189820-6
    ISSN 0095-4829
    ISSN 0095-4829
    DOI 10.1007/978-3-030-87649-4_4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Neurofibromatosis Type 1 with Giant Thrombotic Aneurysm of the Internal Carotid Artery Presenting with Rapid Progression of Visual Disturbance: A Case Report and Literature Review.

    Kobayashi, Masato / Otani, Naoki / Kajimoto, Ryuta / Katsuhara, Takamichi / Yoshino, Atsuo

    Journal of neurological surgery reports

    2023  Volume 84, Issue 1, Page(s) e6–e10

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2023-01-16
    Publishing country Germany
    Document type Case Reports
    ZDB-ID 2653397-2
    ISSN 2193-6366 ; 2193-6358
    ISSN (online) 2193-6366
    ISSN 2193-6358
    DOI 10.1055/a-2008-4161
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    In stock of ZB MED Cologne/Königswinter

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  3. Article ; Online: Glossopharyngeal neuralgia due to vertebrobasilar dolichoectasia: a case report.

    Chen, Jui Yen / Takizawa, Keita / Ozasa, Kana / Otani, Naoki / Young, Andrew / Noma, Noboru

    Quintessence international (Berlin, Germany : 1985)

    2024  , Page(s) 1–24

    Abstract: Background: Glossopharyngeal neuralgia due to vertebrobasilar dolichoectasia is a rare form of neuropathic pain and presents with diagnostic and therapeutic challenges.: Clinical presentation: A 67-year-old man presented with severe burning pain in ... ...

    Abstract Background: Glossopharyngeal neuralgia due to vertebrobasilar dolichoectasia is a rare form of neuropathic pain and presents with diagnostic and therapeutic challenges.
    Clinical presentation: A 67-year-old man presented with severe burning pain in the left oral cavity, with no explanatory findings during dental and ENT evaluations. TMJ examination revealed tenderness, and panoramic radiographs showed a non-contributory periapical radiolucency. MRI/MRA revealed abnormally tortuous vertebral arteries compressing the glossopharyngeal nerves and the brainstem. Topical lidocaine reduced pain, confirming glossopharyngeal neuralgia (GPN). Carbamazepine was initially ineffective, but at 200 mg pain reduced from 90 to 20 on the visual analog scale. The patient requested and underwent microvascular decompression (MVD) surgery, which eliminated his pain.
    Conclusion: When the vertebral artery compresses the glossopharyngeal nerve, the pain is more intense, attributed to its thicker vascular structure. Local anesthetic testing aids in identifying GPN. Dentists must be skilled in diagnostics and possess anatomical knowledge for accurate evaluation and referral of throat and ear pain.
    Language English
    Publishing date 2024-02-28
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 7436-6
    ISSN 1936-7163 ; 0033-6572
    ISSN (online) 1936-7163
    ISSN 0033-6572
    DOI 10.3290/j.qi.b5031815
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: [Decompressive Craniectomy for Intracranial Hypertension].

    Otani, Naoki / Yoshino, Atsuo

    No shinkei geka. Neurological surgery

    2021  Volume 49, Issue 5, Page(s) 964–975

    Abstract: Decompressive craniectomy(DC)for intracranial hypertension after traumatic brain injury(TBI)can be divided into two treatment strategies: primary DC and secondary DC. DC has an important intracranial pressure-lowering effect; however, the standard ... ...

    Abstract Decompressive craniectomy(DC)for intracranial hypertension after traumatic brain injury(TBI)can be divided into two treatment strategies: primary DC and secondary DC. DC has an important intracranial pressure-lowering effect; however, the standard treatment has not been established because the treatment policy with respect to surgical indication, optimal timing, and surgical method are often determined according to the empirical rules of each institution. In addition, the effects of DC on clinical outcomes remain unknown. Recently, the results of a large multicenter randomized controlled trial(RCT)about the effects of secondary DC for severe head trauma have been published. The study showed that secondary DC improved the mortality rate but had no effect on functional prognosis. Another RCT about the effects of primary DC for TBI is ongoing and the results are awaited. We herein describe the indications, surgical methods, and issues of DC for TBI based on the results of these clinical trials with a high level of evidence.
    MeSH term(s) Decompressive Craniectomy ; Humans ; Intracranial Hypertension/etiology ; Intracranial Hypertension/surgery
    Language Japanese
    Publishing date 2021-10-06
    Publishing country Japan
    Document type Journal Article ; Multicenter Study ; Randomized Controlled Trial
    ZDB-ID 197053-7
    ISSN 1882-1251 ; 0301-2603
    ISSN (online) 1882-1251
    ISSN 0301-2603
    DOI 10.11477/mf.1436204479
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Trigeminal Neuralgia With Concomitant Continuous Pain Due to Vertebrobasilar Dolichoectasia: A Case Report.

    Takei, Miki / Takizawa, Keita / Okada, Akiko / Otani, Naoki / Noma, Noboru

    Cureus

    2023  Volume 15, Issue 12, Page(s) e49953

    Abstract: This passage discusses a case of trigeminal neuralgia (TN) with continuous pain and hemifacial spasm caused by vertebrobasilar dolichoectasia, a rare condition. The patient experienced ongoing orofacial pain, which initially led to dental treatments. ... ...

    Abstract This passage discusses a case of trigeminal neuralgia (TN) with continuous pain and hemifacial spasm caused by vertebrobasilar dolichoectasia, a rare condition. The patient experienced ongoing orofacial pain, which initially led to dental treatments. After unsuccessful medication (carbamazepine), the patient underwent microvascular decompression to alleviate nerve compression by the elongated vertebral artery. This report highlights the challenge of treating such cases due to the unique nature of neurovascular compression. Additionally, it introduces the concept of TN with concomitant continuous pain and emphasizes the need for comprehensive diagnosis, as vertebrobasilar artery elongation is associated with various symptoms, including TN and hemifacial spasms.
    Language English
    Publishing date 2023-12-05
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.49953
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: In Reply to the Letter to the Editor Regarding "Prophylactic Intraventricular Piping Method Prevents Entrapped Temporal Horn After Removal of Ventricle Trigone Meningioma: Technical Note".

    Toyooka, Terushige / Takeuchi, Satoru / Otani, Naoki / Kumagai, Kosuke / Tomiyama, Arata / Wada, Kojiro / Mori, Kentaro

    World neurosurgery

    2023  Volume 176, Page(s) 257

    MeSH term(s) Humans ; Meningioma/surgery ; Cerebral Ventricles ; Meningeal Neoplasms/surgery ; Temporal Lobe
    Language English
    Publishing date 2023-08-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2023.05.049
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    In stock of ZB MED Cologne/Königswinter

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  7. Book ; Online: Contextualized Word Vector-based Methods for Discovering Semantic Differences with No Training nor Word Alignment

    Nagata, Ryo / Takamura, Hiroya / Otani, Naoki / Kawasaki, Yoshifumi

    2023  

    Abstract: In this paper, we propose methods for discovering semantic differences in words appearing in two corpora based on the norms of contextualized word vectors. The key idea is that the coverage of meanings is reflected in the norm of its mean word vector. ... ...

    Abstract In this paper, we propose methods for discovering semantic differences in words appearing in two corpora based on the norms of contextualized word vectors. The key idea is that the coverage of meanings is reflected in the norm of its mean word vector. The proposed methods do not require the assumptions concerning words and corpora for comparison that the previous methods do. All they require are to compute the mean vector of contextualized word vectors and its norm for each word type. Nevertheless, they are (i) robust for the skew in corpus size; (ii) capable of detecting semantic differences in infrequent words; and (iii) effective in pinpointing word instances that have a meaning missing in one of the two corpora for comparison. We show these advantages for native and non-native English corpora and also for historical corpora.
    Keywords Computer Science - Computation and Language
    Publishing date 2023-05-19
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Ruptured Basilar Artery Perforator Aneurysm Definitely Diagnosed with Intraoperative Microsurgical Findings: Case Report and Literature Review.

    Kumagawa, Takahiro / Otani, Naoki / Kakei, Yuzo / Negishi, Hiroshi / Suma, Takeshi / Yoshino, Atsuo

    NMC case report journal

    2023  Volume 10, Page(s) 1–7

    Abstract: Initial three-dimensional computed tomography and cerebral angiography fail to identify any aneurysm in 20% of cases of subarachnoid hemorrhage. Basilar artery (BA) perforator aneurysms are rare, and approximately 30%-60% were not identified by initial ... ...

    Abstract Initial three-dimensional computed tomography and cerebral angiography fail to identify any aneurysm in 20% of cases of subarachnoid hemorrhage. Basilar artery (BA) perforator aneurysms are rare, and approximately 30%-60% were not identified by initial angiography. A 71-year-old male was transferred with a sudden onset of headache and loss of consciousness. Computed tomography demonstrated subarachnoid hemorrhage, but no ruptured aneurysm was detected. Repeat preoperative cerebral angiography indicated a bifurcation aneurysm of the circumflex branch of the superior cerebellar artery perforator, but microsurgical observation identified the BA perforator aneurysm. If the location of the BA perforator aneurysm cannot be clearly identified, as in this case, repeat angiography should be considered, and the treatment strategy should be decided based on a detailed consideration of the site of the aneurysm.
    Language English
    Publishing date 2023-01-16
    Publishing country Japan
    Document type Case Reports
    ISSN 2188-4226
    ISSN 2188-4226
    DOI 10.2176/jns-nmc.2022-0184
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  9. Article ; Online: Destabilization of vitelline membrane outer layer protein 1 homolog (VMO1) by C-mannosylation.

    Yoshimoto, Satoshi / Suzuki, Takehiro / Otani, Naoki / Takahashi, Daisuke / Toshima, Kazunobu / Dohmae, Naoshi / Simizu, Siro

    FEBS open bio

    2023  Volume 13, Issue 3, Page(s) 490–499

    Abstract: C-mannosylation is a rare type of protein glycosylation whereby a single mannose is added to the first tryptophan in the consensus sequence Trp-Xaa-Xaa-Trp/Cys (in which Xaa represents any amino acid). Its consensus sequence is mainly found in proteins ... ...

    Abstract C-mannosylation is a rare type of protein glycosylation whereby a single mannose is added to the first tryptophan in the consensus sequence Trp-Xaa-Xaa-Trp/Cys (in which Xaa represents any amino acid). Its consensus sequence is mainly found in proteins containing a thrombospondin type-1 repeat (TSR1) domain and in type I cytokine receptors. In these proteins, C-mannosylation affects protein secretion, intracellular localization, and protein stability; however, the role of C-mannosylation in proteins that are not type I cytokine receptors and/or do not contain a TSR1 domain is less well explored. In this study, we focused on human vitelline membrane outer layer protein 1 homolog (VMO1). VMO1, which possesses two putative C-mannosylation sites, is a 21-kDa secreted protein that does not contain a TSR1 domain and is not a type I cytokine receptor. Mass spectrometry analyses revealed that VMO1 is C-mannosylated at Trp
    MeSH term(s) Humans ; Glycosylation ; Mannose/metabolism ; Vitelline Membrane/metabolism ; Protein Transport ; Receptors, Cytokine/metabolism
    Chemical Substances Mannose (PHA4727WTP) ; Receptors, Cytokine
    Language English
    Publishing date 2023-01-30
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2651702-4
    ISSN 2211-5463 ; 2211-5463
    ISSN (online) 2211-5463
    ISSN 2211-5463
    DOI 10.1002/2211-5463.13561
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Destabilization of vitelline membrane outer layer protein 1 homolog (VMO1) by C‐mannosylation

    Yoshimoto, Satoshi / Suzuki, Takehiro / Ōtani, Naoki / Takahashi, Daisuke / Toshima, Kazunobu / Dohmae, Naoshi / Simizu, Siro

    FEBS Open Bio 2023 Mar., v. 13, no. 3, p. 490-499

    2023  , Page(s) 490–499

    Abstract: C‐mannosylation is a rare type of protein glycosylation whereby a single mannose is added to the first tryptophan in the consensus sequence Trp‐Xaa‐Xaa‐Trp/Cys (in which Xaa represents any amino acid). Its consensus sequence is mainly found in proteins ... ...

    Abstract C‐mannosylation is a rare type of protein glycosylation whereby a single mannose is added to the first tryptophan in the consensus sequence Trp‐Xaa‐Xaa‐Trp/Cys (in which Xaa represents any amino acid). Its consensus sequence is mainly found in proteins containing a thrombospondin type‐1 repeat (TSR1) domain and in type I cytokine receptors. In these proteins, C‐mannosylation affects protein secretion, intracellular localization, and protein stability; however, the role of C‐mannosylation in proteins that are not type I cytokine receptors and/or do not contain a TSR1 domain is less well explored. In this study, we focused on human vitelline membrane outer layer protein 1 homolog (VMO1). VMO1, which possesses two putative C‐mannosylation sites, is a 21‐kDa secreted protein that does not contain a TSR1 domain and is not a type I cytokine receptor. Mass spectrometry analyses revealed that VMO1 is C‐mannosylated at Trp¹⁰⁵ but not at Trp⁴⁴. Although C‐mannosylation does not affect the extracellular secretion of VMO1, it destabilizes the intracellular VMO1. In addition, a structural comparison between VMO1 and C‐mannosylated VMO1 showed that the modification of the mannose changes the conformation of three loops in VMO1. Taken together, our results demonstrate the first example of C‐mannosylation for protein destabilization of VMO1.
    Keywords consensus sequence ; cytokine receptors ; cytokines ; glycosylation ; humans ; mannose ; mass spectrometry ; protein secretion ; tryptophan ; vitelline membrane
    Language English
    Dates of publication 2023-03
    Size p. 490-499
    Publishing place John Wiley & Sons, Ltd
    Document type Article ; Online
    Note JOURNAL ARTICLE
    ZDB-ID 2651702-4
    ISSN 2211-5463
    ISSN 2211-5463
    DOI 10.1002/2211-5463.13561
    Database NAL-Catalogue (AGRICOLA)

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