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  1. Article ; Online: Nutrition in Pediatric Liver Disease.

    Menon, Jagadeesh / Shanmugam, Naresh P

    Indian journal of pediatrics

    2024  Volume 91, Issue 4, Page(s) 366–373

    Abstract: In liver disease, there is derangement of appetite, digestion, absorption, assimilation, storage and metabolism of both macro and micronutrients. These derangements have an impact on mortality and morbidity associated with liver diseases. In infants, ... ...

    Abstract In liver disease, there is derangement of appetite, digestion, absorption, assimilation, storage and metabolism of both macro and micronutrients. These derangements have an impact on mortality and morbidity associated with liver diseases. In infants, breast feeds should not be stopped unless there are compelling reasons such as underlying metabolic problem. Parenteral nutrition should be considered only if, oral or nasogastric feeding is not possible. The effect of malnutrition on liver disease and impact of liver failure on nutrition is vicious and nutritional intervention has to be done at the earliest to break that vicious cycle. This chapter gives an overview of nutritional management in acute and chronic liver diseases in children and also its impact on specific clinical scenarios including liver transplantation.
    MeSH term(s) Infant ; Child ; Humans ; Enteral Nutrition ; Nutritional Status ; Liver Diseases ; Malnutrition
    Language English
    Publishing date 2024-02-07
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-024-05036-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 826: Show issues Location:
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  2. Article ; Online: Response to Letter to the Editor: Severity Assessment Scores for Irritable Bowel Syndrome in Children: Are We There Yet?

    Menon, Jagadeesh / Puttiah, Srikanth K

    Journal of pediatric gastroenterology and nutrition

    2023  Volume 77, Issue 2, Page(s) e50–e51

    MeSH term(s) Humans ; Child ; Irritable Bowel Syndrome/diagnosis
    Language English
    Publishing date 2023-04-25
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 603201-1
    ISSN 1536-4801 ; 0277-2116
    ISSN (online) 1536-4801
    ISSN 0277-2116
    DOI 10.1097/MPG.0000000000003813
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Clinical Profile of Hepatitis Associated Aplastic Anemia (HAAA) in Six Children.

    Bharadwaj, Rishab / Menon, Jagadeesh / Kumar, Vimal / Shanmugam, Naresh / Munirathnam, Deenadayalan

    Indian pediatrics

    2023  Volume 60, Issue 5, Page(s) 410–411

    MeSH term(s) Child ; Humans ; Anemia, Aplastic/complications ; Hepatitis ; Hepatitis A
    Language English
    Publishing date 2023-05-10
    Publishing country India
    Document type Letter
    ZDB-ID 402594-5
    ISSN 0974-7559 ; 0019-6061
    ISSN (online) 0974-7559
    ISSN 0019-6061
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  4. Article ; Online: Liver Transplantation for Tyrosinemia Type 1 in the Developing World: Is It Really the Best We Can Offer?: Correspondence.

    Menon, Jagadeesh / Shanmugam, Naresh / Rela, Mohamed

    Indian journal of pediatrics

    2022  Volume 89, Issue 8, Page(s) 839

    MeSH term(s) Amino Acid Metabolism, Inborn Errors ; Humans ; Liver Transplantation ; Tyrosinemias/surgery
    Language English
    Publishing date 2022-06-15
    Publishing country India
    Document type Letter ; Comment
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-022-04229-6
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  5. Article ; Online: Mature Cystic Teratoma of the Gall Bladder Masquerading a "Hepatic Space Occupying Lesion".

    Menon, Jagadeesh / Shanmugam, Naresh / Madathil, Shamnad / Vij, Mukul / Rammohan, Ashwin / Rela, Mohamed

    Journal of pediatric hematology/oncology

    2023  Volume 45, Issue 4, Page(s) 207–208

    MeSH term(s) Humans ; Female ; Gallbladder/diagnostic imaging ; Teratoma/diagnosis ; Teratoma/surgery ; Liver ; Ovarian Neoplasms
    Language English
    Publishing date 2023-03-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1231152-2
    ISSN 1536-3678 ; 1077-4114 ; 0192-8562
    ISSN (online) 1536-3678
    ISSN 1077-4114 ; 0192-8562
    DOI 10.1097/MPH.0000000000002654
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Liver transplantation for co-existing biliary atresia and familial hypercholesterolemia.

    Dhakkal, Rabi / Menon, Jagadeesh / Shanmugam, Naresh / Mishra, Adrija / Vij, Mukul / Rammohan, Ashwin / Rela, Mohamed

    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology

    2023  

    Language English
    Publishing date 2023-07-19
    Publishing country India
    Document type Letter
    ZDB-ID 632595-6
    ISSN 0975-0711 ; 0254-8860
    ISSN (online) 0975-0711
    ISSN 0254-8860
    DOI 10.1007/s12664-023-01411-2
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    Zs.A 2085: Show issues Location:
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  7. Article ; Online: Liver Transplantation for Zellweger Syndrome.

    Menon, Jagadeesh / Shanmugam, Naresh / Vij, Mukul / Rammohan, Ashwin / Rela, Mohamed

    Indian journal of pediatrics

    2023  Volume 91, Issue 5, Page(s) 507–509

    Abstract: Zellweger syndrome or cerebrohepatorenal syndrome is a rare, multisystem disorder occurring due to defect in metabolic pathway within the peroxisomes. Cirrhosis with portal hypertension is an important presentation of these patients. Given its ... ...

    Abstract Zellweger syndrome or cerebrohepatorenal syndrome is a rare, multisystem disorder occurring due to defect in metabolic pathway within the peroxisomes. Cirrhosis with portal hypertension is an important presentation of these patients. Given its progressive, multisystem nature, the role of liver transplantation (LT) in Zellweger syndrome remains undefined and controversial. An 11-y-old boy diagnosed with Zellweger syndrome presented to the authors with decompensated cirrhosis along with bilateral proptosis. After a meticulous evaluation, he was offered an ABO incompatible liver transplantation with his mother being the donor. He had an uneventful post operative period. After a follow up of 24 mo, he has normal graft function, normal cognition along with resolution of proptosis. Therefore, in a group of carefully selected patients with Zellweger syndrome, a liver transplantation can be offered successfully with an excellent prognosis.
    MeSH term(s) Male ; Humans ; Zellweger Syndrome/pathology ; Liver Transplantation ; Liver Cirrhosis ; Hypertension, Portal ; Exophthalmos/pathology ; Liver/pathology
    Language English
    Publishing date 2023-12-20
    Publishing country India
    Document type Journal Article
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-023-04937-7
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  8. Article ; Online: Simultaneous total internal biliary diversion during liver transplantation for progressive familial intrahepatic cholestasis type 1: Standard of care?

    Menon, Jagadeesh / Shanmugam, Naresh / Vij, Mukul / Veerankutty, Fadl H / Rammohan, Ashwin / Rela, Mohamed

    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

    2024  

    Abstract: Patients post liver transplant (LT) with progressive familial intrahepatic cholestasis type 1 (PFIC-1) often develop progressive graft steatohepatitis, intractable diarrhea, and growth failure. A total internal biliary diversion (TIBD) during an LT may ... ...

    Abstract Patients post liver transplant (LT) with progressive familial intrahepatic cholestasis type 1 (PFIC-1) often develop progressive graft steatohepatitis, intractable diarrhea, and growth failure. A total internal biliary diversion (TIBD) during an LT may prevent or reverse these adverse events. Children with PFIC-1 who underwent an LT at our institute were divided into 2 groups, A and B based on the timeline where we started offering a TIBD in association with LT. Pre-LT parameters, intraoperative details, and posttransplant complications like graft steatosis and diarrhea were also analyzed between the 2 groups, and their growth velocity was measured in the follow-up period. Of 550 pediatric LT performed between 2011 and 2022, 13 children underwent LT for PFIC-1. Group A had 7 patients (A1-A7) and group B had 6 (B1-B6). Patients A1, A4, B4, and B5 had a failed partial internal biliary diversion before offering them an LT. Patients A1, A2, and A6 in group A died in the post-LT period (2 early allograft dysfunction and 1 posttransplant lymphoproliferative disorder) whereas A3, A4, and A5 had graft steatosis in the follow-up period. A4 was offered a TIBD 4 years after LT following which the graft steatosis fully resolved. In group B, B1, B2, B5, and B6 underwent TIBD during LT, and B3 and B4 had it 24 and 5 months subsequently for intractable diarrhea and graft steatosis. None of the patients in group B demonstrated graft steatosis or diarrhea and had good growth catch-up during follow-up. We demonstrate that simultaneous TIBD in patients undergoing LT should be a standard practice as it helps dramatically improve outcomes in PFIC-1 as it prevents graft steatosis and/or fibrosis, diarrhea, and improves growth catch-up.
    Language English
    Publishing date 2024-02-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2006866-9
    ISSN 1527-6473 ; 1527-6465
    ISSN (online) 1527-6473
    ISSN 1527-6465
    DOI 10.1097/LVT.0000000000000351
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Knot-Not Uncommon.

    Aneja, Aradhana / Menon, Jagadeesh / Bolia, Rishi / Lal, Sadhna B

    Indian journal of pediatrics

    2021  Volume 89, Issue 4, Page(s) 409–410

    Language English
    Publishing date 2021-11-09
    Publishing country India
    Document type Journal Article
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-021-04001-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Liver transplantation in tight junction protein-2 deficiency associated liver disease.

    Menon, Jagadeesh / Shanmugam, Naresh / Vij, Mukul / Rammohan, Ashwin / Rela, Mohamed

    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

    2022  Volume 28, Issue 11, Page(s) 1796–1799

    MeSH term(s) Humans ; Liver Diseases ; Liver Transplantation/adverse effects ; Tight Junction Proteins ; Zonula Occludens-2 Protein
    Chemical Substances Tight Junction Proteins ; Zonula Occludens-2 Protein
    Language English
    Publishing date 2022-06-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2006866-9
    ISSN 1527-6473 ; 1527-6465
    ISSN (online) 1527-6473
    ISSN 1527-6465
    DOI 10.1002/lt.26515
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