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  1. Article ; Online: El discurso metafórico en la poesía erótica de Carlos Germán Belli

    Alejandro Giancarlo Mautino Guillén

    Tesis (Lima), Vol 13, Iss 16, Pp 11-

    2020  Volume 24

    Abstract: ... en la construcción del discurso erótico en la poesía de Carlos Germán Belli. Desde nuestra perspectiva, las metáforas ...

    Abstract En este artículo analizamos la función fundamental que tienen los elementos metafóricos en la construcción del discurso erótico en la poesía de Carlos Germán Belli. Desde nuestra perspectiva, las metáforas y los discursos deglutientes y vigilantes en su poética construyen una singular reflexión sobre la cotidianidad del acto erótico a través del cuerpo. Para tal propósito nos apoyamos en la neorretórica y la lingüística cognitiva para entender la relación entre pensamiento-lenguaje vinculados al discurso poético erótico en algunos poemas del autor de Sextinas y otros poemas (1970).
    Keywords discurso ; erotismo ; sistema metafórico ; discurso deglutiente ; discurso vigilante ; History of scholarship and learning. The humanities ; AZ20-999 ; Literature (General) ; PN1-6790 ; Arts in general ; NX1-820
    Language Spanish
    Publishing date 2020-06-01T00:00:00Z
    Publisher Universidad Nacional Mayor de San Marcos, Facultad de Letras y Ciencias Humanas
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Direct admission to home hospitalization from the emergency department: feasible, efficient, and necessary.

    Bibiano Guillén, Carlos

    Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias

    2023  Volume 35, Issue 3, Page(s) 163–164

    Title translation Ingreso directo desde urgencias a domicilio: factible, eficiente y necesario.
    MeSH term(s) Humans ; Hospitalization ; Emergency Service, Hospital
    Language English
    Publishing date 2023-06-23
    Publishing country Spain
    Document type Editorial
    ZDB-ID 2127173-2
    ISSN 2386-5857 ; 2386-5857
    ISSN (online) 2386-5857
    ISSN 2386-5857
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Editorial: Progression to Diabetes: Molecular and cellular mechanisms.

    Guillén, Carlos / Garcia-Ocana, Adolfo

    Frontiers in endocrinology

    2023  Volume 14, Page(s) 1141337

    MeSH term(s) Humans ; Diabetes Mellitus, Type 2 ; Diabetes Mellitus, Type 1
    Language English
    Publishing date 2023-02-07
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2023.1141337
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Changes of

    González-Orozco, Carlos E / Guillén, Esther García / Cuvi, Nicolás

    Royal Society open science

    2023  Volume 10, Issue 4, Page(s) 230229

    Abstract: ... ...

    Abstract The
    Language English
    Publishing date 2023-04-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2787755-3
    ISSN 2054-5703
    ISSN 2054-5703
    DOI 10.1098/rsos.230229
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  5. Article: Targeting pancreatic beta cell death in type 2 diabetes by polyphenols.

    García-Aguilar, Ana / Guillén, Carlos

    Frontiers in endocrinology

    2022  Volume 13, Page(s) 1052317

    Abstract: Diabetes is a very complex disease which is characterized by the appearance of insulin resistance that is primarily compensated by an increase in pancreatic beta cell mass, generating hyperinsulinemia. After time, pancreatic beta cells die by apoptosis ... ...

    Abstract Diabetes is a very complex disease which is characterized by the appearance of insulin resistance that is primarily compensated by an increase in pancreatic beta cell mass, generating hyperinsulinemia. After time, pancreatic beta cells die by apoptosis appearing in the second phase of the disease, and characterized by hypoinsulinemia. There are multiple conditions that can alter pancreatic beta cell homeostasis and viability, being the most relevant ones; ER stress, cytotoxicity by amylin, mTORC1 hyperactivity, oxidative stress, mitochondrial dysfunction, inflammation and alterations in autophagy/mitophagy flux. In addition, the possible effects that different polyphenols could exert in the modulation of these mechanisms and regulating pancreatic beta cell viability are analyzed. It is necessary a profound analysis and understanding of all the possible mechanisms involved in the control and maintenance of pancreatic beta cell viability to develop more accurate and target treatments for controlling beta cell homeostasis and preventing or even reversing type 2 diabetes mellitus.
    MeSH term(s) Humans ; Insulin-Secreting Cells ; Diabetes Mellitus, Type 2/drug therapy ; Polyphenols/pharmacology ; Islet Amyloid Polypeptide ; Insulin Resistance
    Chemical Substances Polyphenols ; Islet Amyloid Polypeptide
    Language English
    Publishing date 2022-11-17
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2022.1052317
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Multi-Organ Crosstalk with Endocrine Pancreas: A Focus on How Gut Microbiota Shapes Pancreatic Beta-Cells.

    Fernández-Millán, Elisa / Guillén, Carlos

    Biomolecules

    2022  Volume 12, Issue 1

    Abstract: Type 2 diabetes (T2D) results from impaired beta-cell function and insufficient beta-cell mass compensation in the setting of insulin resistance. Current therapeutic strategies focus their efforts on promoting the maintenance of functional beta-cell mass ...

    Abstract Type 2 diabetes (T2D) results from impaired beta-cell function and insufficient beta-cell mass compensation in the setting of insulin resistance. Current therapeutic strategies focus their efforts on promoting the maintenance of functional beta-cell mass to ensure appropriate glycemic control. Thus, understanding how beta-cells communicate with metabolic and non-metabolic tissues provides a novel area for investigation and implicates the importance of inter-organ communication in the pathology of metabolic diseases such as T2D. In this review, we provide an overview of secreted factors from diverse organs and tissues that have been shown to impact beta-cell biology. Specifically, we discuss experimental and clinical evidence in support for a role of gut to beta-cell crosstalk, paying particular attention to bacteria-derived factors including short-chain fatty acids, lipopolysaccharide, and factors contained within extracellular vesicles that influence the function and/or the survival of beta cells under normal or diabetogenic conditions.
    MeSH term(s) Diabetes Mellitus, Type 2/metabolism ; Gastrointestinal Microbiome/physiology ; Humans ; Insulin Resistance ; Insulin-Secreting Cells/metabolism ; Metabolic Diseases/metabolism
    Language English
    Publishing date 2022-01-08
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2701262-1
    ISSN 2218-273X ; 2218-273X
    ISSN (online) 2218-273X
    ISSN 2218-273X
    DOI 10.3390/biom12010104
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Draft genomes of two phylotype I and II

    Galiano-Murillo, Fiorella / Salas-Lara, Vidal / Echandi, Carlos / Brenes-Guillén, Laura / Uribe-Lorío, Lorena

    Microbiology resource announcements

    2024  Volume 13, Issue 3, Page(s) e0104223

    Abstract: Bacteria from RSSC hold agricultural significance as they are the causal agents of bacterial wilt. Here, we report the draft genomes of two bacteria extracted from vascular tissues of infected tomato plants. Isolate RALF-MA was classified ... ...

    Abstract Bacteria from RSSC hold agricultural significance as they are the causal agents of bacterial wilt. Here, we report the draft genomes of two bacteria extracted from vascular tissues of infected tomato plants. Isolate RALF-MA was classified as
    Language English
    Publishing date 2024-01-31
    Publishing country United States
    Document type Journal Article
    ISSN 2576-098X
    ISSN (online) 2576-098X
    DOI 10.1128/mra.01042-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: About

    Laura Adalys Guillén León / Carlos Miguel Campos Sánchez

    Edumecentro, Vol 15, Iss 1, Pp e2475-e

    Guidance for student self-preparation in the Otorhinolaryngology subject

    2023  Volume 2475

    Keywords Special aspects of education ; LC8-6691 ; Medicine (General) ; R5-920
    Language Spanish
    Publishing date 2023-05-01T00:00:00Z
    Publisher Universidad de Ciencias Médicas de Villa Clara “Dr. Serafín Ruíz de Zárate Ruíz"
    Document type Article ; Online
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  9. Book ; Online: An adaptive standardisation model for Day-Ahead electricity price forecasting

    Sebastián, Carlos / González-Guillén, Carlos E. / Juan, Jesús

    2023  

    Abstract: The study of Day-Ahead prices in the electricity market is one of the most popular problems in time series forecasting. Previous research has focused on employing increasingly complex learning algorithms to capture the sophisticated dynamics of the ... ...

    Abstract The study of Day-Ahead prices in the electricity market is one of the most popular problems in time series forecasting. Previous research has focused on employing increasingly complex learning algorithms to capture the sophisticated dynamics of the market. However, there is a threshold where increased complexity fails to yield substantial improvements. In this work, we propose an alternative approach by introducing an adaptive standardisation to mitigate the effects of dataset shifts that commonly occur in the market. By doing so, learning algorithms can prioritize uncovering the true relationship between the target variable and the explanatory variables. We investigate four distinct markets, including two novel datasets, previously unexplored in the literature. These datasets provide a more realistic representation of the current market context, that conventional datasets do not show. The results demonstrate a significant improvement across all four markets, using learning algorithms that are less complex yet widely accepted in the literature. This significant advancement unveils opens up new lines of research in this field, highlighting the potential of adaptive transformations in enhancing the performance of forecasting models.
    Keywords Statistics - Applications ; Computer Science - Machine Learning ; Statistics - Methodology
    Subject code 330
    Publishing date 2023-11-05
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Slow Mohs Micrographic Surgery for the Treatment of Genital Dermatofibrosarcoma Protuberans: A Single-Center Series of 5 Cases.

    Algarra-Sahuquillo, Judit / Llombart, Beatriz / Serra-Guillen, Carlos / Sanmartin, Onofre

    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.

    2024  

    Language English
    Publishing date 2024-03-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1227586-4
    ISSN 1524-4725 ; 1076-0512
    ISSN (online) 1524-4725
    ISSN 1076-0512
    DOI 10.1097/DSS.0000000000004175
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    In stock of ZB MED Cologne/Königswinter

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