LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 1660

Search options

  1. Article ; Online: Cañete Ochoa, J., Fernández Lanza, F., De Santiago, M. (Coords.)

    Luis Armando González

    Realidad, Iss

    Premios Cervantes. Discursos, 1976-1990

    2003  Volume 91

    Abstract: No hay resúmenes disponibles Realidad: Revista de Ciencias Sociales y Humanidades No. 91, 2003: 161- ... ...

    Abstract No hay resúmenes disponibles Realidad: Revista de Ciencias Sociales y Humanidades No. 91, 2003: 161-163
    Keywords Reseñas de libros ; Literatura española ; Literatura hispanoamericana ; Social sciences (General) ; H1-99
    Language Spanish
    Publishing date 2003-02-01T00:00:00Z
    Publisher Universidad Centroamericana José Simeón Cañas
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  2. Article ; Online: Viral strain-dependent impact of plant developmental stages on the nestedness and modularity of plant-virus interaction matrices.

    Melero, Izan / Elena, Santiago F / González, Rubén

    microPublication biology

    2023  Volume 2023

    Abstract: This study examines the specificity of adaptation of lineages of turnip mosaic virus that were experimentally evolved ... ...

    Abstract This study examines the specificity of adaptation of lineages of turnip mosaic virus that were experimentally evolved from
    Language English
    Publishing date 2023-11-09
    Publishing country United States
    Document type Journal Article
    ISSN 2578-9430
    ISSN (online) 2578-9430
    DOI 10.17912/micropub.biology.000943
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Host developmental stages shape the evolution of a plant RNA virus.

    Melero, Izan / González, Rubén / Elena, Santiago F

    Philosophical transactions of the Royal Society of London. Series B, Biological sciences

    2023  Volume 378, Issue 1873, Page(s) 20220005

    Abstract: Viruses are obligate pathogens that entirely rely on their hosts to complete their infectious cycle. The outcome of viral infections depends on the status of the host. Host developmental stage is an important but sometimes overlooked factor impacting ... ...

    Abstract Viruses are obligate pathogens that entirely rely on their hosts to complete their infectious cycle. The outcome of viral infections depends on the status of the host. Host developmental stage is an important but sometimes overlooked factor impacting host-virus interactions. This impact is especially relevant in a context where climate change and human activities are altering plant development. To better understand how different host developmental stages shape virus evolution, we experimentally evolved turnip mosaic virus (TuMV) on
    MeSH term(s) Humans ; Arabidopsis/genetics ; RNA, Plant ; Potyvirus/genetics ; Plant Viruses/genetics ; Plant Diseases
    Chemical Substances RNA, Plant
    Language English
    Publishing date 2023-02-06
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 208382-6
    ISSN 1471-2970 ; 0080-4622 ; 0264-3839 ; 0962-8436
    ISSN (online) 1471-2970
    ISSN 0080-4622 ; 0264-3839 ; 0962-8436
    DOI 10.1098/rstb.2022.0005
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Genetic basis of

    Butkovic, Anamarija / Ellis, Thomas James / Gonzalez, Ruben / Jaegle, Benjamin / Nordborg, Magnus / Elena, Santiago F

    eLife

    2024  Volume 12

    Abstract: Plant viruses account for enormous agricultural losses worldwide, and the most effective way to combat them is to identify genetic material conferring plant resistance to these pathogens. Aiming to identify genetic associations with responses to ... ...

    Abstract Plant viruses account for enormous agricultural losses worldwide, and the most effective way to combat them is to identify genetic material conferring plant resistance to these pathogens. Aiming to identify genetic associations with responses to infection, we screened a large panel of
    MeSH term(s) Humans ; Arabidopsis/genetics ; Potyvirus/genetics ; Arabidopsis Proteins/genetics ; Necrosis ; Plant Diseases/genetics
    Chemical Substances Arabidopsis Proteins
    Language English
    Publishing date 2024-01-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2687154-3
    ISSN 2050-084X ; 2050-084X
    ISSN (online) 2050-084X
    ISSN 2050-084X
    DOI 10.7554/eLife.89749
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: The Interplay between the Host Microbiome and Pathogenic Viral Infections.

    González, Rubén / Elena, Santiago F

    mBio

    2021  Volume 12, Issue 6, Page(s) e0249621

    Abstract: The microorganisms associated with an organism, the microbiome, have a strong and wide impact in their host biology. In particular, the microbiome modulates both the host defense responses and immunity, thus influencing the fate of infections by ... ...

    Abstract The microorganisms associated with an organism, the microbiome, have a strong and wide impact in their host biology. In particular, the microbiome modulates both the host defense responses and immunity, thus influencing the fate of infections by pathogens. Indeed, this immune modulation and/or interaction with pathogenic viruses can be essential to define the outcome of viral infections. Understanding the interplay between the microbiome and pathogenic viruses opens future venues to fight viral infections and enhance the efficacy of antiviral therapies. An increasing number of researchers are focusing on microbiome-virus interactions, studying diverse combinations of microbial communities, hosts, and pathogenic viruses. Here, we aim to review these studies, providing an integrative overview of the microbiome impact on viral infection across different pathosystems.
    MeSH term(s) Animals ; Bacteria/genetics ; Bacterial Physiological Phenomena ; Humans ; Microbial Interactions ; Microbiota ; Virus Diseases/immunology ; Virus Diseases/microbiology ; Virus Diseases/virology ; Virus Physiological Phenomena ; Viruses/classification ; Viruses/genetics
    Language English
    Publishing date 2021-11-02
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2557172-2
    ISSN 2150-7511 ; 2161-2129
    ISSN (online) 2150-7511
    ISSN 2161-2129
    DOI 10.1128/mBio.02496-21
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Effects of cross-pollination among non-Bt and pyramided Bt corn expressing cry proteins in seed mixtures on resistance development of dual-gene resistant Helicoverpa zea.

    Yang, Fei / Kennedy, Haley / Santiago-González, José C / Kerns, David L

    Pest management science

    2022  Volume 78, Issue 8, Page(s) 3260–3265

    Abstract: ... We found higher fitness for F: Conclusion: These results suggest that cross-pollination ...

    Abstract Background: Seed mixture strategy can guarantee the compliance of planting non-Bt crops to host the susceptible insects for resistance management. However, pollen movement between Bt and non-Bt corn in the mixed plantings could reduce the efficacy of this strategy for ear-feeding insects. Few studies have evaluated the effects of cross-pollination among non-Bt and pyramided Bt corn in seed mixtures on the resistance development of insects possessing multiple resistances. Here, we provided the first study to investigate whether cross-pollination in mixed plantings of pyramided Bt corn producing Cry1A.105 and Cry2Ab2 would increase the dominance of resistance of dual-gene resistant populations of Helicoverpa zea, a target of pyramided Bt corn and cotton in the USA.
    Results: We compared the survival and development of susceptible, dual-gene resistant (resistance to both Cry1 and Cry2 proteins) and heterozygous genotypes of H. zea in the laboratory on non-Bt and pyramided Bt corn ears collected from mixed plantings and structured plantings in the field. We found higher fitness for F
    Conclusion: These results suggest that cross-pollination in mixed plantings will significantly increase the dominance of resistance by supporting survival of heterozygous insects for dual-gene resistant populations of H. zea, and therefore accelerate evolution of resistance to pyramided Bt crops. © 2022 Society of Chemical Industry.
    MeSH term(s) Animals ; Bacillus thuringiensis/genetics ; Bacillus thuringiensis/metabolism ; Bacterial Proteins/pharmacology ; Crops, Agricultural/genetics ; Endotoxins/pharmacology ; Hemolysin Proteins/genetics ; Hemolysin Proteins/metabolism ; Hemolysin Proteins/pharmacology ; Insecticide Resistance/genetics ; Larva/metabolism ; Moths ; Plants, Genetically Modified/genetics ; Plants, Genetically Modified/metabolism ; Pollination ; Seeds/metabolism ; Zea mays/genetics ; Zea mays/metabolism
    Chemical Substances Bacterial Proteins ; Endotoxins ; Hemolysin Proteins
    Language English
    Publishing date 2022-06-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2001705-4
    ISSN 1526-4998 ; 1526-498X
    ISSN (online) 1526-4998
    ISSN 1526-498X
    DOI 10.1002/ps.6945
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Genetic basis of Arabidopsis thaliana responses to infection by naïve and adapted isolates of turnip mosaic virus

    Anamarija Butkovic / Thomas James Ellis / Ruben Gonzalez / Benjamin Jaegle / Magnus Nordborg / Santiago F Elena

    eLife, Vol

    2024  Volume 12

    Abstract: Plant viruses account for enormous agricultural losses worldwide, and the most effective way to combat them is to identify genetic material conferring plant resistance to these pathogens. Aiming to identify genetic associations with responses to ... ...

    Abstract Plant viruses account for enormous agricultural losses worldwide, and the most effective way to combat them is to identify genetic material conferring plant resistance to these pathogens. Aiming to identify genetic associations with responses to infection, we screened a large panel of Arabidopsis thaliana natural inbred lines for four disease-related traits caused by infection by A. thaliana-naïve and -adapted isolates of the natural pathogen turnip mosaic virus (TuMV). We detected a strong, replicable association in a 1.5 Mb region on chromosome 2 with a 10-fold increase in relative risk of systemic necrosis. The region contains several plausible causal genes as well as abundant structural variation, including an insertion of a Copia transposon into a Toll/interleukin receptor (TIR-NBS-LRR) coding for a gene involved in defense, that could be either a driver or a consequence of the disease-resistance locus. When inoculated with TuMV, loss-of-function mutant plants of this gene exhibited different symptoms than wild-type plants. The direction and severity of symptom differences depended on the adaptation history of the virus. This increase in symptom severity was specific for infections with the adapted isolate. Necrosis-associated alleles are found worldwide, and their distribution is consistent with a trade-off between resistance during viral outbreaks and a cost of resistance otherwise, leading to negative frequency-dependent selection.
    Keywords emerging viruses ; experimental evolution ; frequency-dependent selection ; GWAS ; Potyvirus ; resistance genes ; Medicine ; R ; Science ; Q ; Biology (General) ; QH301-705.5
    Subject code 580
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher eLife Sciences Publications Ltd
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  8. Article: Population Genetic Structure of

    Ramilo, Andrea / Rodríguez, Helena / Pascual, Santiago / González, Ángel F / Abollo, Elvira

    Animals : an open access journal from MDPI

    2023  Volume 13, Issue 2

    Abstract: The European hake, one of the most commercially valuable species in ICES fishing areas, is considered an important neglected source of zoonotic risk by nematode parasites belonging to the ... ...

    Abstract The European hake, one of the most commercially valuable species in ICES fishing areas, is considered an important neglected source of zoonotic risk by nematode parasites belonging to the genus
    Language English
    Publishing date 2023-01-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani13020197
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article: An experimental census of retrons for DNA production and genome editing.

    Khan, Asim G / Rojas-Montero, Matías / González-Delgado, Alejandro / Lopez, Santiago C / Fang, Rebecca F / Shipman, Seth L

    bioRxiv : the preprint server for biology

    2024  

    Abstract: Retrons are bacterial immune systems that use reverse transcribed DNA as a detector of phage infection. They are also increasingly deployed as a component of biotechnology. For genome editing, for instance, retrons are modified so that the reverse ... ...

    Abstract Retrons are bacterial immune systems that use reverse transcribed DNA as a detector of phage infection. They are also increasingly deployed as a component of biotechnology. For genome editing, for instance, retrons are modified so that the reverse transcribed DNA (RT-DNA) encodes an editing donor. Retrons are commonly found in bacterial genomes; thousands of unique retrons have now been predicted bioinformatically. However, only a small number have been characterized experimentally. Here, we add substantially to the corpus of experimentally studied retrons. We synthesized >100 previously untested retrons to identify the natural sequence of RT-DNA they produce, quantify their RT-DNA production, and test the relative efficacy of editing using retron-derived donors to edit bacterial genomes, phage genomes, and human genomes. We add 62 new empirically determined, natural RT-DNAs, which are not predictable from the retron sequence alone. We report a large diversity in RT-DNA production and editing rates across retrons, finding that top performing editors outperform those used in previous studies, and are drawn from a subset of the retron phylogeny.
    Language English
    Publishing date 2024-01-26
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2024.01.25.577267
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: La señal de la cruz: un automatismo muy poco frecuente en la epilepsia del lóbulo temporal. Descripción de dos casos.

    Fernández-Cabrera, A / López-González, F J / García-de Soto, J / Pardellas-Santiago, E / Lara-Lezama, L B / Rodríguez-Osorio, X

    Revista de neurologia

    2023  Volume 77, Issue 4, Page(s) 105–108

    Abstract: Introduction: In the evaluation of drug-resistant epilepsy (DRF), a detailed analysis of the semiology is essential to establish a diagnostic hypothesis of the location of the epileptogenic zone. Cross-sign (CS) is a very infrequent complex manual ... ...

    Title translation The sign of the cross: a very rare automatism in temporal lobe epilepsy. Two case reports.
    Abstract Introduction: In the evaluation of drug-resistant epilepsy (DRF), a detailed analysis of the semiology is essential to establish a diagnostic hypothesis of the location of the epileptogenic zone. Cross-sign (CS) is a very infrequent complex manual automatism described for the first time in 2008 and rarely reported in the literature.
    Case report: We present two cases from our series of patients monitored by videoEEG, one of whom also studied with deep electrodes, in which we describe the location of the discharge while performing the CS. A bibliographic review is also carried out to try to establish a localizing and/or lateralizing value of this sign.
    Conclusion: The sign of the cross is a rare ictal automatism that occurs in patients with temporal lobe epilepsy. The hand used to make the sign of the cross is the dominant one, regardless of the origin of the crises.
    MeSH term(s) Humans ; Epilepsy, Temporal Lobe ; Automatism ; Drug Resistant Epilepsy ; Electrodes ; Hand
    Language Spanish
    Publishing date 2023-07-25
    Publishing country Spain
    Document type Case Reports ; English Abstract
    ZDB-ID 1468278-3
    ISSN 1576-6578 ; 0210-0010
    ISSN (online) 1576-6578
    ISSN 0210-0010
    DOI 10.33588/rn.7704.2023128
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top