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Article ; Online: Long term effectiveness of live herpes zoster vaccine.

Mbinta, James F / Simpson, Colin R

2023 Volume 383, Page(s) 2497

MeSH term(s)	Humans ; Herpes Zoster Vaccine ; Herpes Zoster/prevention & control ; Vaccines, Attenuated ; Vaccination
Chemical Substances	Herpes Zoster Vaccine ; Vaccines, Attenuated
Language	English
Publishing date	2023-11-08
Publishing country	England
Document type	Editorial ; Comment
ZDB-ID	1362901-3
ISSN	1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
ISSN (online)	1756-1833
ISSN	0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
DOI	10.1136/bmj.p2497
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Article ; Online: Flawed MIREC fluoride and intelligence quotient publications: A failed attempt to undermine community water fluoridation.

Guichon, Juliet R / Cooper, Colin / Rugg-Gunn, Andrew / Dickinson, James A

Community dentistry and oral epidemiology

2024

Abstract: Objective: To assess the evidence presented in a set of articles that use the Canadian Maternal-Infant Research on Environmental Chemicals (MIREC) study database to claim that community water fluoridation (CWF) is associated with harm to foetal and ... ...

Abstract	Objective: To assess the evidence presented in a set of articles that use the Canadian Maternal-Infant Research on Environmental Chemicals (MIREC) study database to claim that community water fluoridation (CWF) is associated with harm to foetal and infant cognitive development. Methods: Critical appraisal of measurements and processes in the MIREC database, and articles derived therefrom. MIREC's cohort is approximately 2000 pregnant women recruited in 10 centres across Canada, 2008-2011, leading to measuring 512 children aged 3-6 years in six cities. Fluoride exposure was measured by city fluoridation status, self-reports and maternal spot urine samples. Intelligence Quotient (IQ) was measured using the Wechsler Preschool and Primary Scale of Intelligence (WPPSI-III) by different assessors in each city. Results: MIREC's fluoride and IQ measurements are invalid and therefore cannot support the claim that CWF is associated with IQ decline in children. Conclusions: The MIREC fluoride-IQ articles' results should be considered unacceptable for legal and policy purposes; other water fluoridation studies and systematic reviews show no effect of fluoridation on cognition.
Language	English
Publishing date	2024-03-25
Publishing country	Denmark
Document type	Journal Article
ZDB-ID	189172-8
ISSN	1600-0528 ; 0301-5661
ISSN (online)	1600-0528
ISSN	0301-5661
DOI	10.1111/cdoe.12954
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Article ; Online: Tensor Tympani and Stapedial Tendon Reconstruction for Postoperative Hyperacusis after Tendon Lysis for Middle Ear Myoclonus.

Khandalavala, Karl R / Dornhoffer, James R / Poling, Gayla L / Driscoll, Colin L

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology

2024

Abstract: Objective: To present a method for repair of the stapedial and tensor tympani tendons in a patient with hyperacusis after a tendon lysis procedure.: Patients: A 71-year-old professional musician who presented to clinic with debilitating hyperacusis ... ...

Abstract	Objective: To present a method for repair of the stapedial and tensor tympani tendons in a patient with hyperacusis after a tendon lysis procedure. Patients: A 71-year-old professional musician who presented to clinic with debilitating hyperacusis following a tensor tympani and stapedial tendon lysis procedure to treat middle ear myoclonus. Interventions: A novel procedure for reapproximation of the tensor tympani and stapedial tendons into their native insertion points using periosteal grafts and nitinol wire. Main outcomes measures: Stapedial reflex measurements, uncomfortable loudness level, and subjective patient experience. Results: Postoperatively, the patient had objective improvement in hyperacusis with return of acoustic reflexes in the affected ear and durable improvements in their frequency-specific uncomfortable loudness levels. Conclusions: This case describes the debilitating complication of hyperacusis following tendon lysis and highlights the importance of maximizing behavioral and medical measures prior to undergoing surgical intervention for middle ear myoclonus.
Language	English
Publishing date	2024-03-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	2036790-9
ISSN	1537-4505 ; 1531-7129
ISSN (online)	1537-4505
ISSN	1531-7129
DOI	10.1097/MAO.0000000000004175
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Article ; Online: Multi-center experience with outpatient total hip arthroplasty via a standard posterolateral approach.

Smith, Thomas D / Wilson, Ian R / Burnell, Colin / Vernon, James / Hedden, David R / Turgeon, Thomas R

PloS one

2024 Volume 19, Issue 3, Page(s) e0292003

Abstract: Background: This study sought to evaluate the safety, efficacy, and resource utilization of a pilot outpatient surgery program for total hip arthroplasty compared to traditional inpatient total hip arthroplasty performed via the posterolateral approach.! ...

Abstract	Background: This study sought to evaluate the safety, efficacy, and resource utilization of a pilot outpatient surgery program for total hip arthroplasty compared to traditional inpatient total hip arthroplasty performed via the posterolateral approach. Methods: A cohort of 68 patients from two sites were enrolled in a regional pilot project for outpatient total hip arthroplasty (THA) and matched 1:1 against a cohort of patients undergoing routine inpatient THA. Data was extracted retrospectively from patient and hospital charts including adverse events (AE), readmission within 90 days, emergency room (ER) visits, patient calls, patient-reported outcome measures, length of stay, and multiple surgical variables. Results: The outpatient group had a mean hospital stay of 13 hours, whereas the inpatient group had a mean of 58 hours (p<0.001). Three outpatients and four inpatients experienced post-op complications. Three inpatients and one outpatient visited the ER within 8 weeks of surgery. No difference in pre-operative hemoglobin (p = 0.210), or surgical blood loss (p = 0.550) was found between study groups. There was no difference found between groups regarding Oxford-12 Hip Score improvement, nor satisfaction at six months, one and two years (p>0.125). Conclusion: This study demonstrates that outpatient THA using the posterolateral approach is as safe and effective as inpatient THA for overall healthy and carefully screened patients, based on the low rate of AEs observed and similar patient outcomes reported. Significantly reduced time in hospital demonstrates the reduced healthcare resources associated with outpatient THA.
MeSH term(s)	Humans ; Arthroplasty, Replacement, Hip/adverse effects ; Outpatients ; Retrospective Studies ; Pilot Projects ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Length of Stay ; Patient Readmission
Language	English
Publishing date	2024-03-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0292003
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Initial Experiences with the Envoy Acclaim

Dornhoffer, James R / Lawlor, Skye K / Saoji, Aniket A / Driscoll, Colin L W

Journal of clinical medicine

2023 Volume 12, Issue 18

Abstract: Introduction: ...

Abstract	Introduction:
Language	English
Publishing date	2023-09-10
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm12185875
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Article ; Online: Quantifying the feeding behavior and trophic impact of a widespread oceanic ctenophore.

Potter, Betsy / Corrales-Ugalde, Marco / Townsend, James P / Colin, Sean P / Sutherland, Kelly R / Costello, John H / Collins, Richard / Gemmell, Brad J

Scientific reports

2023 Volume 13, Issue 1, Page(s) 2292

Abstract: Oceanic ctenophores are widespread predators on pelagic zooplankton. While data on coastal ctenophores often show strong top-down predatory impacts in their ecosystems, differing morphologies, prey capture mechanisms and behaviors of oceanic species ... ...

Abstract	Oceanic ctenophores are widespread predators on pelagic zooplankton. While data on coastal ctenophores often show strong top-down predatory impacts in their ecosystems, differing morphologies, prey capture mechanisms and behaviors of oceanic species preclude the use of coastal data to draw conclusion on oceanic species. We used high-resolution imaging methods both in situ and in the laboratory to quantify interactions of Ocyropsis spp. with natural copepod prey. We confirmed that Ocyropsis spp. uses muscular lobe contraction and a prehensile mouth to capture prey, which is unique amongst ctenophores. This feeding mechanism results in high overall capture success whether encountering single or multiple prey between the lobes (71 and 81% respectively). However, multiple prey require several attempts for successful capture whereas single prey are often captured on the first attempt. Digestion of adult copepods takes 44 min at 25 °C and does not vary with ctenophore size. At high natural densities, we estimate that Ocyropsis spp. consume up to 40% of the daily copepod standing stock. This suggests that, when numerous, Ocyropsis spp. can exert strong top-down control on oceanic copepod populations. At more common densities, these animals consume only a small proportion of the daily copepod standing stock. However, compared to data from pelagic fishes and oceanic medusae, Ocyropsis spp. appears to be the dominant copepod predator in this habitat.
MeSH term(s)	Animals ; Ctenophora ; Ecosystem ; Feeding Behavior ; Oceans and Seas ; Nutritional Status ; Predatory Behavior ; Copepoda ; Food Chain
Language	English
Publishing date	2023-02-09
Publishing country	England
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-27955-z
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Article ; Online: Coordinated Same- or Next-Day Radiosurgery and Cochlear Implantation for Vestibular Schwannoma.

Macielak, Robert J / Dornhoffer, James R / Plitt, Aaron R / Neff, Brian A / Driscoll, Colin L W / Carlson, Matthew L / Link, Michael J

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology

2024 Volume 45, Issue 4, Page(s) 430–433

Abstract: Objective: To describe the experience and results from coordinated and closely scheduled radiosurgery and cochlear implantation (CI) in a vestibular schwannoma (VS) cohort.: Patients: Patients with VS who underwent radiosurgery followed by CI on the ... ...

Abstract	Objective: To describe the experience and results from coordinated and closely scheduled radiosurgery and cochlear implantation (CI) in a vestibular schwannoma (VS) cohort. Patients: Patients with VS who underwent radiosurgery followed by CI on the same or next day. Interventions: Interventions included sequential radiosurgery and CI. Main outcome measures: Tumor control defined by tumor growth on posttreatment surveillance and audiometric outcomes including consonant-nucleus-consonant words and AzBio sentences in quiet. Results: In total, six patients were identified that met the inclusion criteria, with an age range of 38 to 69 years and tumor sizes ranging from 2.0 to 16.3 mm. All patients successfully underwent radiosurgery and CI on the same or immediately successive day. Postoperatively, all patients obtained open-set speech recognition. Consonant-nucleus-consonant word scores ranged from 40 to 88% correct, and AzBio scores ranged from 44 to 94% correct. During posttreatment magnetic resonance imaging surveillance, which ranged from 12 to 68 months, all tumors were noted to be adequately visualized, and no tumor progression was noted. Conclusion: Coordinated radiosurgery and CI can be safely performed in patients with VS on the same or next day, serving to decrease burden on patients and increase access to this vital rehabilitative strategy.
MeSH term(s)	Humans ; Adult ; Middle Aged ; Aged ; Cochlear Implantation/methods ; Neuroma, Acoustic/surgery ; Radiosurgery/methods ; Retrospective Studies ; Audiometry ; Speech Perception ; Treatment Outcome ; Cochlear Implants
Language	English
Publishing date	2024-02-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	2036790-9
ISSN	1537-4505 ; 1531-7129
ISSN (online)	1537-4505
ISSN	1531-7129
DOI	10.1097/MAO.0000000000004149
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Article ; Online: Initial Experiences with the Envoy Acclaim ® Fully Implanted Cochlear Implant

James R. Dornhoffer / Skye K. Lawlor / Aniket A. Saoji / Colin L. W. Driscoll

Journal of Clinical Medicine, Vol 12, Iss 5875, p

2023 Volume 5875

Abstract: Introduction: Cochlear implantation has become the standard of care for the treatment of moderate-to-profound bilateral sensorineural hearing loss. However, current technologies, all of which rely on an external sound processor, have intrinsic ... ...

Abstract	Introduction: Cochlear implantation has become the standard of care for the treatment of moderate-to-profound bilateral sensorineural hearing loss. However, current technologies, all of which rely on an external sound processor, have intrinsic limitations that prevent certain activities and diagnostics, thus hampering full integration into a patient’s lifestyle. The Envoy Medical (White Bear Lake, MN, USA) Acclaim ® fully implanted cochlear implant is a new device currently undergoing testing that has been designed to alleviate many of the current constraints by housing all components within the patient, thus allowing for near-constant use in many environments that are not conducive to a traditional cochlear implant. Methods : As part of an Early Feasibility Study, three adult implant candidates were implanted with the Acclaim ® cochlear implant. Surgical video and photography were taken, and initial observations were recorded. Implantation with the Acclaim ® device is largely similar to a traditional cochlear implant, with modifications to allow room for the implanted sensor as well as the implantation of a battery in the subcutaneous tissues of the chest. Results: This study demonstrates a step-by-step overview of implanting the Acclaim ® and discusses initial insight and experiences with the first three implantations with this new device. Conclusions: All three surgeries proceeded without complication, and at activation, all three patients were hearing through their devices. Surgery is more technically challenging compared to a standard cochlear implant, but the skills needed can all be mastered by a dedicated otologic surgeon.
Keywords	cochlear implant ; fully-implantable ; internal device ; Medicine ; R
Subject code	333
Language	English
Publishing date	2023-09-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
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Article ; Online: 3D Bioprinted Liver-on-a-Chip for Drug Cytotoxicity Screening.

Huh, JunTae / Parra, Joao Paulo R L L / Copus, Joshua S / Kang, Hyun-Wook / Bishop, Colin E / Soker, Shay / Murphy, Sean / Shupe, Thomas D / Yoo, James J / Lee, Sang Jin / Atala, Anthony

Tissue engineering. Part A

2024

Abstract: Tissues on a chip are sophisticated three-dimensional (3D) ...

Abstract	Tissues on a chip are sophisticated three-dimensional (3D)
Language	English
Publishing date	2024-01-30
Publishing country	United States
Document type	Journal Article
ZDB-ID	2420582-5
ISSN	1937-335X ; 1937-3341
ISSN (online)	1937-335X
ISSN	1937-3341
DOI	10.1089/ten.TEA.2023.0212
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Article ; Online: Envenomation by the spotted harlequin snake, Homoroselaps lacteus (Linnaeus) 1754 (Serpentes: Atractaspidinae).

Tilbury, Colin R / Peacock, Faansie / Harvey, James

Toxicon : official journal of the International Society on Toxinology

2021 Volume 198, Page(s) 151–155

Abstract: Two cases of envenomation from the small, semi-fossorial, front-fanged colubrid Homoroselaps lacteus are presented and the recent literature reviewed. In addition to local oedema and lymphadenopathy, the development of significant subcutaneous loco- ... ...

Abstract	Two cases of envenomation from the small, semi-fossorial, front-fanged colubrid Homoroselaps lacteus are presented and the recent literature reviewed. In addition to local oedema and lymphadenopathy, the development of significant subcutaneous loco-regional bruising suggest that damage to capillary basement membrane and possibly other underlying anti-haemostatic effects may pertain to the clinical syndrome. Although local clinical effects may appear dramatic, due to the small volumes of venom that can be injected, it is considered that envenomation is unlikely to cause life-threatening effects.
MeSH term(s)	Animals ; Edema ; Snake Bites ; Snake Venoms ; Snakes ; Tooth
Chemical Substances	Snake Venoms
Language	English
Publishing date	2021-05-05
Publishing country	England
Document type	Journal Article
ZDB-ID	204479-1
ISSN	1879-3150 ; 0041-0101
ISSN (online)	1879-3150
ISSN	0041-0101
DOI	10.1016/j.toxicon.2021.04.020
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