LIVIVO - Search results -

Search results

Result 1 - 10 of total 3235

Search options

Article ; Online: Respuesta de IFN-y e Il-4 en ratones inoculados con una proteína G recombinante del virus de la rabia

Edith Rojas-Anaya / Fernando Esquivel-Guadarrama / Estela Escribano-Romero / Ana Belén Blázquez / Graciela Tapia Pérez / Lilia Soto Ruíz / Elizabeth Loza-Rubio

Revista Mexicana de Ciencias Pecuarias, Vol 6, Iss 4, Pp 419-

2015 Volume 430

Abstract: El objetivo de este estudio fue comparar el comportamiento de IFN-  e IL-4 en ratones inoculados ... con proteína G recombinante del virus de la rabia, que se expresa en maíz transgénico o baculovirus ... de la rabia inactivado vía im; Grupo 2, proteína G recombinante deri vada de plantas por vía oral; Grupo 3 ...

Abstract	El objetivo de este estudio fue comparar el comportamiento de IFN-  e IL-4 en ratones inoculados con proteína G recombinante del virus de la rabia, que se expresa en maíz transgénico o baculovirus. Para este pr opósito, grupos de ratones se inocularon de la siguiente manera: Grupo 1, vacuna contra el virus de la rabia inactivado vía im; Grupo 2, proteína G recombinante deri vada de plantas por vía oral; Grupo 3, proteína G expresada en baculovirus vía im; Grupo 4, proteína G expresada en baculovirus por vía oral; Grupo 5, maíz no tran sformado por vía oral. Los niveles de IFN-  e IL-4 y los anticuerpos específicos se evaluaron cada 15 días. El desafío se realizó a los 60 días post inoculación (pi). Los grupos 1 y 3 promovieron un a mejor respuesta humoral. Por otro lado, los resultados demostraron que los mismos grupos mostraron los mejores niveles de IFN -  en el día 10 pi; mientras que la IL-4 se detectó en el día 15 pi. Para el estudio de supervivencia, el 83 % de los ratones inmunizados con vacuna inactivada, maíz y los inoculados im con extractos de baculovirus sob revivieron la infección viral. La proteína G de la rabia recombinante expresada en baculovirus promovió IFN-  y los anticuerpos de una manera similar a la vacuna de rabia inactivada. A pesar de esto los ratones alime ntados con maíz transgénico sobrevivieron al desafío en el mismo porcentaje que el grupo 3.
Keywords	Animal culture ; SF1-1100 ; Veterinary medicine ; SF600-1100
Language	English
Publishing date	2015-01-01T00:00:00Z
Publisher	Instituto Nacional del Investigaciones Forestales, Agrícolas y Pecuarias
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Is a Genetic Diathesis for Poor Nutrition Becoming More Crucial Due to the Uniformity of COVID Social Stress?

DeSoto, M Catherine

Nutrients

2023 Volume 15, Issue 4

Abstract: ... when a sharp increase in prevalence is entirely the result of an environmental change (e.g., COVID anxiety and ... environmental changes may make biological diatheses for nutritional deficiencies even more problematic. The concept of G ... E interaction is dissected to clarify a non-intuitive scenario: heritability may increase, even ...

Abstract	The important role of nutrition in proper neural functioning and mental health has seen wider acceptance, but is still sadly under recognized given the existent body of research. This Special Issue was designed to unite authoritative information on this topic in one volume. This editorial provides an overview of the issue, and suggests that the combination of social isolation, lack of exercise, and remaining indoors that overtook industrialized societies during 2020 are specific factors expected to change the Gene × Environment interactions for anxiety and depression. Importantly, the recent environmental changes may make biological diatheses for nutritional deficiencies even more problematic. The concept of G × E interaction is dissected to clarify a non-intuitive scenario: heritability may increase, even when a sharp increase in prevalence is entirely the result of an environmental change (e.g., COVID anxiety and isolation). Key research is highlighted, specific genetic examples are noted, and theoretical implications regarding natural selection are discussed.
MeSH term(s)	Humans ; Anxiety/epidemiology ; Anxiety Disorders ; COVID-19 ; Depression/epidemiology ; Genetic Predisposition to Disease ; Malnutrition
Language	English
Publishing date	2023-02-15
Publishing country	Switzerland
Document type	Editorial ; Introductory Journal Article
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu15040960
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: Perceptual Observer Modeling Reveals Likely Mechanisms of Face Expression Recognition Deficits in Depression.

Soto, Fabian A / Beevers, Christopher G

Biological psychiatry. Cognitive neuroscience and neuroimaging

2024

Abstract: ... in selectivity (i.e., information used to detect emotion), but depression was associated with a stronger ...

Abstract	Background: Deficits in face emotion recognition are well documented in depression, but the underlying mechanisms are poorly understood. Psychophysical observer models provide a way to precisely characterize such mechanisms. Using model-based analyses, we tested 2 hypotheses about how depression may reduce sensitivity to detect face emotion: 1) via a change in selectivity for visual information diagnostic of emotion or 2) via a change in signal-to-noise ratio in the system performing emotion detection. Methods: Sixty adults, one half meeting criteria for major depressive disorder and the other half healthy control participants, identified sadness and happiness in noisy face stimuli, and their responses were used to estimate templates encoding the visual information used for emotion identification. We analyzed these templates using traditional and model-based analyses; in the latter, the match between templates and stimuli, representing sensory evidence for the information encoded in the template, was compared against behavioral data. Results: Estimated happiness templates produced sensory evidence that was less strongly correlated with response times in participants with depression than in control participants, suggesting that depression was associated with a reduced signal-to-noise ratio in the detection of happiness. The opposite results were found for the detection of sadness. We found little evidence that depression was accompanied by changes in selectivity (i.e., information used to detect emotion), but depression was associated with a stronger influence of face identity on selectivity. Conclusions: Depression is more strongly associated with changes in signal-to-noise ratio during emotion recognition, suggesting that deficits in emotion detection are driven primarily by deprecated signal quality rather than suboptimal sampling of information used to detect emotion.
Language	English
Publishing date	2024-02-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	2879089-3
ISSN	2451-9030 ; 2451-9022
ISSN (online)	2451-9030
ISSN	2451-9022
DOI	10.1016/j.bpsc.2024.01.011
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Book ; Online: Chapter Machine Learning Techniques to Mitigate Nonlinear Phase Noise in Moderate Baud Rate Optical Communication Systems

Bogoni, A. / Ferná, o / ndez, E. / Cá, a / rdenas Soto, A. / Guerrero Gonzalez, N. / Serafino, G. / Ghelfi, P.

2020

Keywords	Computing & information technology ; nonlinear phase noise, clustering, Voronoi, decision boundary
Size	1 Online-Ressource
Publisher	InTechOpen
Document type	Book ; Online
Note	English ; Open Access
HBZ-ID	HT021047546
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article ; Online: Improving the validity of neuroimaging decoding tests of invariant and configural neural representation.

Soto, Fabian A / Narasiwodeyar, Sanjay

PLoS computational biology

2023 Volume 19, Issue 1, Page(s) e1010819

Abstract: ... representation of a stimulus property is invariant or specific to a particular stimulus context (e.g., Is object ... information from classifier decision variables rather than only accuracies (i.e., using the decoding ...

Abstract	Many research questions in sensory neuroscience involve determining whether the neural representation of a stimulus property is invariant or specific to a particular stimulus context (e.g., Is object representation invariant to translation? Is the representation of a face feature specific to the context of other face features?). Between these two extremes, representations may also be context-tolerant or context-sensitive. Most neuroimaging studies have used operational tests in which a target property is inferred from a significant test against the null hypothesis of the opposite property. For example, the popular cross-classification test concludes that representations are invariant or tolerant when the null hypothesis of specificity is rejected. A recently developed neurocomputational theory suggests two insights regarding such tests. First, tests against the null of context-specificity, and for the alternative of context-invariance, are prone to false positives due to the way in which the underlying neural representations are transformed into indirect measurements in neuroimaging studies. Second, jointly performing tests against the nulls of invariance and specificity allows one to reach more precise and valid conclusions about the underlying representations, particularly when the null of invariance is tested using the fine-grained information from classifier decision variables rather than only accuracies (i.e., using the decoding separability test). Here, we provide empirical and computational evidence supporting both of these theoretical insights. In our empirical study, we use encoding of orientation and spatial position in primary visual cortex as a case study, as previous research has established that these properties are encoded in a context-sensitive way. Using fMRI decoding, we show that the cross-classification test produces false-positive conclusions of invariance, but that more valid conclusions can be reached by jointly performing tests against the null of invariance. The results of two simulations further support both of these conclusions. We conclude that more valid inferences about invariance or specificity of neural representations can be reached by jointly testing against both hypotheses, and using neurocomputational theory to guide the interpretation of results.
MeSH term(s)	Neuroimaging ; Magnetic Resonance Imaging/methods ; Neurosciences ; Pattern Recognition, Visual
Language	English
Publishing date	2023-01-23
Publishing country	United States
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	2193340-6
ISSN	1553-7358 ; 1553-734X
ISSN (online)	1553-7358
ISSN	1553-734X
DOI	10.1371/journal.pcbi.1010819
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Unconscious Manipulation of Conceptual Representations with Decoded Neurofeedback Impacts Search Behavior.

Margolles, Pedro / Elosegi, Patxi / Mei, Ning / Soto, David

The Journal of neuroscience : the official journal of the Society for Neuroscience

2024 Volume 44, Issue 2

Abstract: ... neural patterns akin to those observed when visually perceiving real-world entities (e.g., dogs ... an associative DecNef approach to imbue perceptual meaning (e.g., dogs) into Japanese hiragana characters ...

Abstract	The necessity of conscious awareness in human learning has been a long-standing topic in psychology and neuroscience. Previous research on non-conscious associative learning is limited by the low signal-to-noise ratio of the subliminal stimulus, and the evidence remains controversial, including failures to replicate. Using functional MRI decoded neurofeedback, we guided participants from both sexes to generate neural patterns akin to those observed when visually perceiving real-world entities (e.g., dogs). Importantly, participants remained unaware of the actual content represented by these patterns. We utilized an associative DecNef approach to imbue perceptual meaning (e.g., dogs) into Japanese hiragana characters that held no inherent meaning for our participants, bypassing a conscious link between the characters and the dogs concept. Despite their lack of awareness regarding the neurofeedback objective, participants successfully learned to activate the target perceptual representations in the bilateral fusiform. The behavioral significance of our training was evaluated in a visual search task. DecNef and control participants searched for dogs or scissors targets that were pre-cued by the hiragana used during DecNef training or by a control hiragana. The DecNef hiragana did not prime search for its associated target but, strikingly, participants were impaired at searching for the targeted perceptual category. Hence, conscious awareness may function to support higher-order associative learning. Meanwhile, lower-level forms of re-learning, modification, or plasticity in existing neural representations can occur unconsciously, with behavioral consequences outside the original training context. The work also provides an account of DecNef effects in terms of neural representational drift.
MeSH term(s)	Male ; Female ; Humans ; Animals ; Dogs ; Neurofeedback ; Learning ; Unconsciousness ; Consciousness ; Conditioning, Classical ; Magnetic Resonance Imaging
Language	English
Publishing date	2024-01-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	604637-x
ISSN	1529-2401 ; 0270-6474
ISSN (online)	1529-2401
ISSN	0270-6474
DOI	10.1523/JNEUROSCI.1235-23.2023
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1668: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Mediastinal Myofibroblastic Inflammatory Tumor Compressing the Airway: An Unusual Cause of Dyspnea in a 12-Year-Old.

Tautiva, Camila / Loria, Gloriana / Soto, Manuel E

Cureus

2023 Volume 15, Issue 2, Page(s) e34596

Abstract: A healthy 12-year-old presented with wheezing and progressive dyspnea over a 10-month period. He had several general physician consultations and emergency visits during this time and was treated as an asthma exacerbation with no clinical response. He was ...

Abstract	A healthy 12-year-old presented with wheezing and progressive dyspnea over a 10-month period. He had several general physician consultations and emergency visits during this time and was treated as an asthma exacerbation with no clinical response. He was referred to the pediatric pulmonologist and a tracheal deviation in his previous two chest X-rays was noted, therefore further studies were performed. A severe extrinsic tracheal compression due to a mediastinal mass was documented. He was taken into surgery where a partial resection of the tumor was made. The biopsy of the tumor reported an inflammatory myofibroblastic tumor (IMT), a rare tumor with an atypical presentation, which made this case a diagnostic challenge.
Language	English
Publishing date	2023-02-03
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.34596
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Presymptomatic Reduction of Individuality in the App

Ehret, Fanny / Pelz, Meike S / Senko, Anna N / Soto, Karla E G / Liu, Hang / Kempermann, Gerd

Biological psychiatry

2023 Volume 94, Issue 9, Page(s) 721–731

Abstract: Background: One-third of the risk for Alzheimer's disease is explained by environment and lifestyle, but Alzheimer's disease pathology might also affect lifestyle and thereby impair the individual potential for health behavior and prevention.: Methods! ...

Abstract	Background: One-third of the risk for Alzheimer's disease is explained by environment and lifestyle, but Alzheimer's disease pathology might also affect lifestyle and thereby impair the individual potential for health behavior and prevention. Methods: We examined in mice how the App Results: After 4 months of ENR, the mean and variability of plasma ApoE were increased in NL-F mice, suggesting a presymptomatic variation in pathogenic processes. Roaming entropy as a measure of behavioral activity was continuously assessed with radiofrequency identification (RFID) technology and revealed reduced habituation and variance in NL-F mice compared with control animals, which do not carry a Beyreuther/Iberian mutation. Intraindividual variation decreased, while behavioral stability was reduced in NL-F mice. Seven months after discontinuation of ENR, we found no difference in plaque size and number, but ENR increased variance in hippocampal plaque counts in NL-F mice. A reactive increase in adult hippocampal neurogenesis in NL-F mice, known from other models, was normalized by ENR. Conclusions: Our data suggest that while NL-F has early effects on individual behavioral patterns in response to ENR, there are lasting effects on cellular plasticity even after the discontinuation of ENR. Hence, early behavior matters for maintaining individual behavioral trajectories and brain plasticity even under maximally constrained conditions.
MeSH term(s)	Animals ; Mice ; Alzheimer Disease/genetics ; Alzheimer Disease/pathology ; Amyloid beta-Peptides ; Amyloid beta-Protein Precursor/genetics ; Disease Models, Animal ; Individuality ; Mice, Transgenic
Chemical Substances	Amyloid beta-Peptides ; Amyloid beta-Protein Precursor
Language	English
Publishing date	2023-04-17
Publishing country	United States
Document type	Journal Article
ZDB-ID	209434-4
ISSN	1873-2402 ; 0006-3223
ISSN (online)	1873-2402
ISSN	0006-3223
DOI	10.1016/j.biopsych.2023.04.009
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 720: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Formation of volatile chlorinated and brominated products during low temperature thermal decomposition of the representative PFAS perfluorohexane sulfonate (PFHxS) in the presence of NaCl and NaBr.

Zhao, Yuwei / Koster van Groos, Paul G / Thakur, Nikita / Fuller, Mark E / Soto, Anthony / Hatzinger, Paul B

Environmental pollution (Barking, Essex : 1987)

2024 Volume 348, Page(s) 123782

Abstract: ... of mixed halogenated VOF may form during thermal treatment of PFAS at relatively low temperature (e.g., 500 ... thermal treatment (i.e., incineration) has been utilized for PFAS treatment, but this requires significant ...

Abstract	Per- and polyfluoroalkyl substances (PFAS) are synthetic organofluorine compounds known for their chemical and physical stability as well as their wide range of uses. Some PFAS are widely distributed in the environment, leading to concerns related to both environmental and human health. High temperature thermal treatment (i.e., incineration) has been utilized for PFAS treatment, but this requires significant infrastructure and energy, prompting interest in lower temperature approaches that may still lead to efficient destruction. Lower treatment temperatures, however, increase the potential for incomplete PFAS mineralization and formation of volatile organofluorine (VOF) products. Herein, we report the formation of novel VOF products that include chlorinated and brominated compounds during the thermal treatment of potassium perfluorohexane sulfonate (PFHxS), a representative perfluoroalkyl acid (PFAA). By comparing the gas chromatography-mass spectrometry (GC-MS) results of known VOF stocks to evolved VOF during thermal treatment of PFAS, the formation of perfluorohexyl chloride and perfluorohexyl bromide was observed when PFHxS was heated at temperatures between 275 and 475 °C in the presence of NaCl and NaBr, respectively. To our knowledge, this is the first report of chlorinated or brominated VOF products during thermal treatment of a PFAA. These findings suggest that a range of mixed halogenated VOF may form during thermal treatment of PFAS at relatively low temperature (e.g., 500 °C) and that these can be a function of salts present in the matrix.
MeSH term(s)	Humans ; Sodium Chloride ; Temperature ; Fluorocarbons ; Alkanesulfonates ; Alkanesulfonic Acids
Chemical Substances	perflexane (FX3WJ41CMX) ; Sodium Chloride (451W47IQ8X) ; Fluorocarbons ; Alkanesulfonates ; Alkanesulfonic Acids
Language	English
Publishing date	2024-03-12
Publishing country	England
Document type	Journal Article
ZDB-ID	280652-6
ISSN	1873-6424 ; 0013-9327 ; 0269-7491
ISSN (online)	1873-6424
ISSN	0013-9327 ; 0269-7491
DOI	10.1016/j.envpol.2024.123782
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2599: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Substance and Behavioral Addictions among American Indian and Alaska Native Populations.

Soto, Claradina / West, Amy E / Ramos, Guadalupe G / Unger, Jennifer B

International journal of environmental research and public health

2022 Volume 19, Issue 5

Abstract: ... behavioral (e.g., gambling) addictions.: Conclusions: There is a dearth of research on behavioral ... among AIANs.: Results: The literature search identified 69 articles. Numerous risk factors (i.e ... life stressors, severe trauma, family history of alcohol use) and protective factors (i.e., ethnic identity ...

Abstract	Objective: This paper examines substance and behavioral addictions among American Indian and Alaska Natives (AIAN) to identify the structural and psychosocial risk and cultural protective factors that are associated with substance use and behavioral addictions. Methods: Five databases were used to search for peer reviewed articles through December 2021 that examined substance and behavioral addictions among AIANs. Results: The literature search identified 69 articles. Numerous risk factors (i.e., life stressors, severe trauma, family history of alcohol use) and protective factors (i.e., ethnic identity, family support) influence multiple substance (i.e., commercial tobacco, alcohol, opioid, stimulants) and behavioral (e.g., gambling) addictions. Conclusions: There is a dearth of research on behavioral addictions among AIANs. Unique risk factors in AIAN communities such as historical trauma and socioeconomic challenges have interfered with traditional cultural resilience factors and have increased the risk of behavioral addictions. Future research on resilience factors and effective prevention and treatment interventions could help AIANs avoid behavioral addictions.
MeSH term(s)	Alaska Natives ; Behavior, Addictive/epidemiology ; Humans ; Indians, North American/psychology ; Substance-Related Disorders/epidemiology ; Substance-Related Disorders/prevention & control ; American Indian or Alaska Native
Language	English
Publishing date	2022-03-03
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph19052974
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

Order via subito

Details ▾
- Full text online
- Order with fees

To top

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Order via subito