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Book ; Conference proceedings ; Online: Proceedings of the John Hall Symposium

Bergquist, James C / Diddams, Scott A / Hollberg, Leo / Kaleth, Loree / Oates, Chris / Ye, Jun

In Honor of John Hall on the Occasion of His 70th Birthday

2006

Abstract: This symposium was a dedication to John L Hall, who was recently awarded the Nobel Prize in Physics ... of some of his achievements, the research he inspired, and the great friendships he has built. Nobel Prize Report:. John L ...

Abstract	This symposium was a dedication to John L Hall, who was recently awarded the Nobel Prize in Physics, (report below). The symposium was a celebration of his striking career in physics and his impressive record of achievements. Papers included in this volume offer brief and personal glimpses of some of his achievements, the research he inspired, and the great friendships he has built. Nobel Prize Report:. John L Hall, a Scientist Emeritus of the National Institute of Standards and Technology and a Fellow of JILA (joint institute of NIST and University of Colorado) has been awarded the 2005 Nobel
Language	English
Size	Online-Ressource (198 p)
Publisher	World Scientific Publishing Company
Publishing place	Singapore
Document type	Book ; Conference proceedings ; Online
Note	Description based upon print version of record
ISBN	9789812567451 ; 9812567453
Database	Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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Article: Transfeminine Gender Confirmation Surgery with Penile Inversion Vaginoplasty: An Initial Experience.

Loree, John T / Burke, Mark S / Rippe, Bridgett / Clarke, Sarah / Moore, Samuel H / Loree, Thom R

Plastic and reconstructive surgery. Global open

2020 Volume 8, Issue 5, Page(s) e2873

Abstract: To detail the early experience with and results of a transfeminine (TF) genital reconstruction at an established plastic surgery practice in Western New York.: Methods: Between June 2016 and June 2019, 30 patients underwent penile inversion ... ...

Abstract	To detail the early experience with and results of a transfeminine (TF) genital reconstruction at an established plastic surgery practice in Western New York. Methods: Between June 2016 and June 2019, 30 patients underwent penile inversion vaginoplasty for TF gender reassignment. All patients fulfilled World Professional Association for Transgender Health and NY State criteria for reassignment surgery. All surgeries were carried out at a large, government-owned tertiary care center. Results: There were 30 patients in this retrospective study, with a mean age of 37 years (SD 5.4) and a mean body mass index of 27.3 kg/m Conclusions: TF gender reassignment is a novel, challenging set of procedures for the specialty of plastic surgery. With appropriate consideration and technique, penile inversion vaginoplasty is a safe, effective means of achieving this goal.
Language	English
Publishing date	2020-05-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	2851682-5
ISSN	2169-7574 ; 2169-7574
ISSN (online)	2169-7574
ISSN	2169-7574
DOI	10.1097/GOX.0000000000002873
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Article: Recurrent Spontaneous Intracranial Hypotension (SIH) and the Durability of Repeat Epidural Blood Patch (EBP).

Hazama, Ali / Awawdeh, Fakhri / Braley, Alexander / Loree, John / Swarnkar, Amar / Chin, Lawrence S / Krishnamurthy, Satish

Cureus

2023 Volume 15, Issue 7, Page(s) e41457

Abstract: Objective: Spontaneous intracranial hypotension (SIH) remains a rare and difficult clinical entity to diagnose and treat. Epidural blood patch (EBP) of the dural sac is the mainstay definitive treatment for refractory cases and has mixed efficacy. We ... ...

Abstract	Objective: Spontaneous intracranial hypotension (SIH) remains a rare and difficult clinical entity to diagnose and treat. Epidural blood patch (EBP) of the dural sac is the mainstay definitive treatment for refractory cases and has mixed efficacy. We sought to evaluate the recent efficacy and outcomes of EBP for SIH at our institution. Methods: Twenty-three patients (14 women, 9 men, mean age 49) were seen and treated for SIH between Summer 2009 and Spring 2018 at the same institution. All patients underwent brain MRI with and without gadolinium contrast and T2-weighted spine MRI. Targeted EBP was placed one or two vertebral levels below areas of suspected leak, while the patient was positioned in the lateral decubitus position. Patients were seen in the outpatient setting within a week following initial EBP and repeat EBP was offered to patients with persistent symptoms. Patients were followed if symptoms persisted or for 6 months following clinical relief of symptoms. Results: 22/23 (95.7%) patients presented with complaints of orthostatic headache, and 3 (13%) patients presented with altered mental status (AMS) or focal neurologic deficit. Brain MRI demonstrated pachymeningeal enhancement in 16/23 (69.6%) patients, and 5/23 (21.7%) patients had a subdural hematoma (SDH) present. Dural leaks were successfully identified in 18/23 (78.3%) patients. 12/23 (52.2%) patients had symptomatic relief with initial EBP, and 5/23 (21.7%) patients received further EBPs for persistent disease with all achieving relief after repeat EBP. 5/12 (41.7%) of patients had recurrent symptoms after initial relief with EBP, and 4/5 (80%) were successfully treated with a second EBP. The mean initial EBP volume and number of EBPs per patient were 21.7 mL (median 20 mL, 7-40 mL) and 3.54 (median 1, 1-13) respectively. There was one complication from initial EBP (cervical dural tear requiring operative closure) treated with open surgical management successfully. In total, 18/23 (78.2%) patients are currently asymptomatic with regard to their SIH. The mean follow-up in this cohort was 2.6 years (median 1.8 years, 1.8 months-9.27 years). Conclusions: EBP is a viable and effective option for the treatment of recurrent SIH caused by cerebrospinal fluid (CSF) leaks.
Language	English
Publishing date	2023-07-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.41457
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Article ; Online: Transverse Colon Primary Tumor Location as a Biomarker in Metastatic Colorectal Cancer: A Pooled Analysis of CCTG/AGITG CO.17 and CO.20 Randomized Clinical Trials.

Solar Vasconcelos, Joao Paulo / Chen, Nan / Titmuss, Emma / Tu, Dongsheng / Brule, Stephanie Y / Goodwin, Rachel / Jonker, Derek J / Price, Timothy / Zalcberg, John R / Moore, Malcolm J / Karapetis, Christos S / Siu, Lillian / Shapiro, Jeremy / Simes, John / Gill, Sharlene / O'Callaghan, Chris J / Loree, Jonathan M

Clinical cancer research : an official journal of the American Association for Cancer Research

2024 Volume 30, Issue 6, Page(s) 1121–1130

Abstract: Purpose: Sidedness is prognostic and predictive of anti-EGFR efficacy in metastatic colorectal cancer (mCRC). Transverse colon has been historically excluded from several analyses of sidedness and the optimal division between left- and right-sided ... ...

Abstract	Purpose: Sidedness is prognostic and predictive of anti-EGFR efficacy in metastatic colorectal cancer (mCRC). Transverse colon has been historically excluded from several analyses of sidedness and the optimal division between left- and right-sided colorectal cancer is unclear. We investigated transverse colon primary tumor location as a biomarker in mCRC. Experimental design: Pooled analysis of CCTG/AGITG CO.17 and CO.20 trials of cetuximab in chemotherapy-refractory mCRC. Outcomes of patients with RAS/BRAF wild-type (WT) mCRC from CO.17 and KRAS WT mCRC from CO.20 were analyzed according to location. Results: A total of 553 patients were analyzed, 32 (5.8%) with cancers from the transverse, 101 (18.3%) from right, and 420 from (75.9%) left colon. Transverse mCRC failed to reach significant benefit from cetuximab versus best supportive care (BSC) for overall survival [OS; median, 5.9 vs. 2.1 months; HR, 0.63; 95% confidence interval (CI), 0.28-1.42; P=0.26] and progression-free survival (PFS; median, 1.8 vs. 1.3 months; HR, 0.57; 95% CI, 0.26-1.28; P=0.16). Analyzing exclusively patients randomized to cetuximab, right-sided and transverse had comparable outcomes for OS (median, 5.6 vs. 5.9 months; HR, 0.82; 95% CI, 0.50-1.34; P=0.43) and PFS (median, 1.9 vs. 1.8 months; HR, 0.78; 95% CI, 0.49-1.26; P=0.31). Patients with left-sided mCRC had superior outcomes with cetuximab compared with transverse for OS (median, 9.7 vs. 5.9 months; HR, 0.42; 95% CI, 0.27-0.67; P=0.0002) and PFS (median, 3.8 vs. 1.8 months; HR, 0,49; 95% CI, 0.31-0.76; P=0.001). Location was not prognostic in patients treated with BSC alone. Conclusions: Transverse mCRC has comparable prognostic and predictive features with right-sided mCRC.
MeSH term(s)	Humans ; Cetuximab/therapeutic use ; Colorectal Neoplasms/drug therapy ; Colorectal Neoplasms/genetics ; Colon, Transverse/pathology ; Randomized Controlled Trials as Topic ; Colonic Neoplasms/drug therapy ; Colonic Neoplasms/genetics ; Rectal Neoplasms/drug therapy ; Biomarkers ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use
Chemical Substances	Cetuximab (PQX0D8J21J) ; Biomarkers
Language	English
Publishing date	2024-01-03
Publishing country	United States
Document type	Meta-Analysis ; Journal Article
ZDB-ID	1225457-5
ISSN	1557-3265 ; 1078-0432
ISSN (online)	1557-3265
ISSN	1078-0432
DOI	10.1158/1078-0432.CCR-23-3275
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Article ; Online: Gaps in Training: Misunderstandings of Airway Management in Medical Students and Internal Medicine Residents.

Tokarz, Ellen / Szymanowski, Adam R / Loree, John T / Muscarella, Joseph

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

2020 Volume 164, Issue 5, Page(s) 938–943

Abstract: Objectives: (1) Evaluate baseline airway knowledge of medical students (MSs) and internal medicine (IM) residents. (2) Improve MS and IM resident understanding of airway anatomy, general tracheostomy and laryngectomy care, and management of airway ... ...

Abstract	Objectives: (1) Evaluate baseline airway knowledge of medical students (MSs) and internal medicine (IM) residents. (2) Improve MS and IM resident understanding of airway anatomy, general tracheostomy and laryngectomy care, and management of airway emergencies. Methods: A before-and-after survey study was carried out over a single academic year. MS and IM resident knowledge was evaluated before and after an educational, grand rounds-style lecture reviewing airway anatomy, tracheostomy tube components, tracheostomy and laryngectomy care, and clinical vignettes. The primary outcome measure was change in pre- and postlecture survey scores. Results: Prelecture surveys were completed by 90 participants, and 83 completed a postlecture assessment. Postlecture scores were statistically improved for all questions on the assessment ( Discussion: While the majority of participants in our study had previously cared for patients with a tracheostomy or laryngectomy, less than half were able to correctly address basic airway emergencies. Senior IM residents were no more proficient than MSs in addressing airway emergencies. The lack of formal airway training places patients at risk with routine care and in emergencies, demonstrating the need for formal airway education for early medical trainees. Implications for practice: Our data demonstrate a serious gap in MS and IM resident knowledge with respect to emergent airway care in patients with tracheostomies and laryngectomies. An interdepartmental collaborative curriculum offers a realistic and potentially life-saving solution for medical trainees.
MeSH term(s)	Airway Management ; Education, Medical ; Education, Medical, Undergraduate ; Educational Measurement ; Humans ; Internal Medicine/education ; Internship and Residency ; Laryngectomy/education ; Prospective Studies ; Tracheostomy/education
Language	English
Publishing date	2020-08-25
Publishing country	England
Document type	Journal Article
ZDB-ID	392085-9
ISSN	1097-6817 ; 0161-6439 ; 0194-5998
ISSN (online)	1097-6817
ISSN	0161-6439 ; 0194-5998
DOI	10.1177/0194599820949528
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Article ; Online: Recovery of Tricuspid Valve Function After Resection of a Primary Ovarian Carcinoid Tumor.

Wong, Jeffrey D / Finlayson, Sarah J / Loree, Jonathan / Straatman, Lynn / Nair, Parvathy / Tsang, Michael Y C / Luong, Christina L / Tsang, Teresa S M / Gin, Kenneth / Jue, John / Yeung, Darwin F

Circulation. Cardiovascular imaging

2023 Volume 16, Issue 11, Page(s) e014772

MeSH term(s)	Female ; Humans ; Tricuspid Valve/diagnostic imaging ; Tricuspid Valve/surgery ; Carcinoid Tumor/diagnostic imaging ; Carcinoid Tumor/surgery ; Carcinoid Tumor/pathology ; Tricuspid Valve Insufficiency/diagnostic imaging ; Tricuspid Valve Insufficiency/etiology ; Tricuspid Valve Insufficiency/surgery ; Ovarian Neoplasms/diagnostic imaging ; Ovarian Neoplasms/surgery ; Ovarian Neoplasms/pathology
Language	English
Publishing date	2023-11-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	2435045-X
ISSN	1942-0080 ; 1941-9651
ISSN (online)	1942-0080
ISSN	1941-9651
DOI	10.1161/CIRCIMAGING.122.014772
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Article ; Online: Race-based reporting and participation of Black individuals in registered pain clinical trials, United States, 2000 to 2019.

Vo, Anh Khoa / Cerdeña, Jessica P / Loree, Jonathan M / Cairns, Brian E / Conklin, Annalijn I / Kaseweter, Kimberley / Chondoma, Lerato / Cragg, Jacquelyn J / Kramer, John L K

Pain

2023 Volume 164, Issue 9, Page(s) 1976–1984

Abstract: Abstract: There are numerous, well-established racial disparities in the management of pain. The degree to which these are evident at the stage of conducting clinical trials is unknown. To address this knowledge gap, we examined race-based reporting, ... ...

Abstract	Abstract: There are numerous, well-established racial disparities in the management of pain. The degree to which these are evident at the stage of conducting clinical trials is unknown. To address this knowledge gap, we examined race-based reporting, participation of Black individuals, and the factors associated with reporting and participation in pain clinical trials in the United States. Data were extracted from Clinicaltrials.gov and published articles. One thousand two hundred trials met our inclusion criteria; 482 (40.2%) reported participant race. More recent, publicly funded, and larger trials were more likely to report race. Of 82,468 participants included in pain clinical trials that reported race, 15,101 were Black individuals (18.3%). Participation of Black individuals was significantly associated with pain type (ß = +27% in cardiovascular disease pain compared with acute pain, P < 0.05), study population (ß = +33% and +7% in pain in minoritized populations and women, respectively, compared with general population, P < 0.05), pain intervention (ß = +7.5% for trials of opioid interventions compared with nonopioid interventions, P < 0.05), and a diverse team of investigators (ß = +8.0% for studies incorporating a visible non-White investigator compared with those that did not, P < 0.05). Our results indicate that representation of Black participants in pain clinical trials generally aligns with national demographics in the United States. Increased representation corresponds with health conditions more prevalent among Black individuals (eg, cardiovascular disease) and with a diverse study team composition. Despite these encouraging results, less than half of pain trials reported race, which introduces potential publication bias and limits external validity.
MeSH term(s)	Humans ; Acute Pain ; Analgesics, Opioid ; Cardiovascular Diseases/epidemiology ; United States/epidemiology ; Black or African American ; Clinical Trials as Topic ; Patient Participation
Chemical Substances	Analgesics, Opioid
Language	English
Publishing date	2023-04-17
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	193153-2
ISSN	1872-6623 ; 0304-3959
ISSN (online)	1872-6623
ISSN	0304-3959
DOI	10.1097/j.pain.0000000000002893
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Article ; Online: Sentinel lymph node biopsy for management of the N0 neck in oral cavity squamous cell carcinoma.

Loree, John T / Popat, Saurin R / Burke, Mark S / Frustino, Jennifer / Grewal, Jeewanjot S / Loree, Thom R

Journal of surgical oncology

2019 Volume 120, Issue 2, Page(s) 101–108

Abstract: Background and objectives: The management of the clinically N0 (cN0) neck is controversial for early stage squamous cell carcinoma of the oral cavity (OSCC). This paper represents a single institution series analyzing the efficacy of sentinel lymph node ...

Abstract	Background and objectives: The management of the clinically N0 (cN0) neck is controversial for early stage squamous cell carcinoma of the oral cavity (OSCC). This paper represents a single institution series analyzing the efficacy of sentinel lymph node biopsy (SNB) for early stage oral cavity cancers. Methods: From 2005 to 2017, 108 patients with cN0 OSCC were treated with primary resection and SNB. Patients with positive biopsy results proceeded to neck dissection with or without adjuvant chemoradiotherapy. Mean follow-up for the entire cohort was 50.8 months (range: 8-147 months). Clinically, 56 patients were T1N0, 49 patients were T2N0, and three patients were T3N0 or greater. Results: Disease-specific survival was 93% within the entire cohort. Sentinel lymph nodes were identified in 95.4% of patients. Twenty one patients had a positive biopsy. There were seven false-negative biopsies. The overall rate of nodal disease was 26%. Accuracy of node biopsy was 93%, with sensitivity of 75%, and negative predictive value of 91%. Recurrence rate was 19% (20/108), with an overall survival of 60% in this subgroup. Conclusion: SNB is a safe, effective, and well tolerated method for staging cN0 OSCC.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Carcinoma, Squamous Cell/mortality ; Carcinoma, Squamous Cell/secondary ; Carcinoma, Squamous Cell/therapy ; Chemoradiotherapy, Adjuvant ; Cohort Studies ; Female ; Humans ; Male ; Middle Aged ; Mouth Neoplasms/mortality ; Mouth Neoplasms/pathology ; Mouth Neoplasms/therapy ; Neck Dissection ; Neoplasm Recurrence, Local/epidemiology ; Neoplasm Staging ; Patient Selection ; Sensitivity and Specificity ; Sentinel Lymph Node Biopsy ; Survival Rate ; Young Adult
Language	English
Publishing date	2019-05-16
Publishing country	United States
Document type	Journal Article
ZDB-ID	82063-5
ISSN	1096-9098 ; 0022-4790
ISSN (online)	1096-9098
ISSN	0022-4790
DOI	10.1002/jso.25494
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Article ; Online: Presurgical induction chemotherapy for squamous cell carcinoma of the tonsil.

Burke, Mark S / Loree, John T / Popat, Saurin R / Ford, Daniel / Kim, Jae / Szymanowski, Adam R / Loree, Thom R

The Laryngoscope

2019 Volume 130, Issue 5, Page(s) 1206–1211

Abstract: Objectives/hypothesis: The indications for and efficacy of induction chemotherapy in the management of squamous cell carcinoma of the head and neck is controversial. With the advent of human papillomavirus (HPV)-related cancers, survival has improved ... ...

Abstract	Objectives/hypothesis: The indications for and efficacy of induction chemotherapy in the management of squamous cell carcinoma of the head and neck is controversial. With the advent of human papillomavirus (HPV)-related cancers, survival has improved significantly. Here we present a group of patients with tonsil cancer treated with induction chemotherapy followed by surgery. Study design: Retrospective cohort study. Methods: Thirty-eight patients with tonsil cancer were treated with induction chemotherapy, consisting of cisplatin and docetaxel, followed by neck dissection and radical tonsillectomy. Twenty-six patients were HPV+, 28 were nonsmokers or long-term former smokers, and 28 were T1/T2. Fourteen patients required postoperative chemoradiotherapy (CRT). Median follow-up time was 4.1 years. Results: A complete response to induction chemotherapy was achieved in 45% (17) of patients. In total, 76% (29/38) of patients were successfully treated: 53% (20/38) with chemotherapy and surgery alone, and 24% (9/38) required postoperative CRT. Almost 90% (23/26) of HPV+ and half (6/12) of HPV- patients are no evidence of disease (NED). HPV status is a significant prognostic factor (P = .02). Only 38% (5/13) of current smokers were NED compared to 96% (24/25) of nonsmokers (P = .0002). All HPV+ nonsmokers (20/20) were NED at last follow-up. Conclusions: In this study, the primary driver of prognosis was smoking status. HPV status and T stage were also important. The prognosis for HPV+ nonsmokers is extremely good; most likely regardless of treatment. Treatment failures have a poor chance of salvage, irrespective of treatment type. With the major exception of HPV- smokers, induction chemotherapy followed by surgery with selective CRT is a viable treatment option for tonsil cancer. Level of evidence: 4 Laryngoscope, 130:1206-1211, 2020.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Antineoplastic Agents/therapeutic use ; Carcinoma, Squamous Cell/drug therapy ; Carcinoma, Squamous Cell/surgery ; Carcinoma, Squamous Cell/virology ; Cisplatin/therapeutic use ; Cohort Studies ; Docetaxel/therapeutic use ; Female ; Humans ; Induction Chemotherapy ; Male ; Middle Aged ; Neck Dissection ; Papillomavirus Infections/drug therapy ; Papillomavirus Infections/surgery ; Preoperative Period ; Retrospective Studies ; Tonsillar Neoplasms/drug therapy ; Tonsillar Neoplasms/surgery ; Tonsillar Neoplasms/virology
Chemical Substances	Antineoplastic Agents ; Docetaxel (15H5577CQD) ; Cisplatin (Q20Q21Q62J)
Language	English
Publishing date	2019-07-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	80180-x
ISSN	1531-4995 ; 0023-852X
ISSN (online)	1531-4995
ISSN	0023-852X
DOI	10.1002/lary.28180
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Article ; Online: Severe COVID-19 outcomes among patients with autoimmune rheumatic diseases or transplantation

John Esdaile / Jacek A Kopec / Diane Lacaille / Na Lu / J Antonio Aviña-Zubieta / Hui Xie / Shelby Marozoff / Jonathan M Loree

BMJ Open, Vol 12, Iss

a population-based matched cohort study

2022 Volume 8

Abstract: Objectives To assess the risk of severe COVID-19 outcomes in patients with autoimmune rheumatic diseases (ARDs) and transplant recipients compared with matched general population comparators.Design Population-based matched cohort study using ... ...

Abstract	Objectives To assess the risk of severe COVID-19 outcomes in patients with autoimmune rheumatic diseases (ARDs) and transplant recipients compared with matched general population comparators.Design Population-based matched cohort study using administrative health data sets.Setting British Columbia, Canada.Participants All adults with test-positive SARS-CoV-2 infections. SARS-CoV-2-positive patients with ARDs and those with transplantation were matched to SARS-CoV-2-positive general population comparators on age (±5 years), sex, month/year of initial positive SARS-CoV-2 test and health authority.Outcome measures COVID-19-related hospitalisations, intensive care unit (ICU) admissions, invasive ventilation and COVID-19-specific mortality. We performed multivariable conditional logistic regression models adjusting for socioeconomic status, Charlson Comorbidity Index, hypertension, rural address and number of previous COVID-19 PCR tests.Results Among 6279 patients with ARDs and 222 transplant recipients, all SARS-CoV-2 test positive, risk of hospitalisation was significantly increased among patients with ARDs (overall ARDs (adjusted OR (aOR) 1.30; 95% CI 1.19 to 1.43)); highest within ARDs: adult systemic vasculitides (aOR 2.18; 95% CI 1.17 to 4.05) and transplantation (aOR 10.56; 95% CI 6.88 to 16.22). Odds of ICU admission were significantly increased among patients with ARDs (overall ARDs (aOR 1.30; 95% CI 1.11 to 1.51)); highest within ARDs: ankylosing spondylitis (aOR 2.03; 95% CI 1.18 to 3.50) and transplantation (aOR 8.13; 95% CI 4.76 to 13.91). Odds of invasive ventilation were significantly increased among patients with ARDs (overall ARDs (aOR 1.60; 95% CI 1.27 to 2.01)); highest within ARDs: ankylosing spondylitis (aOR 2.63; 95% CI 1.14 to 6.06) and transplantation (aOR 8.64; 95% CI 3.81 to 19.61). Risk of COVID-19-specific mortality was increased among patients with ARDs (overall ARDs (aOR 1.24; 95% CI 1.05 to 1.47)); highest within ARDs: ankylosing spondylitis (aOR 2.15; 95% CI 1.02 to 4.55) and ...
Keywords	Medicine ; R
Subject code	610
Language	English
Publishing date	2022-08-01T00:00:00Z
Publisher	BMJ Publishing Group
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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