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  1. Article: Does Obesity Influence Women's Decision Making about the Mode of Delivery?

    Walędziak, Maciej / Różańska-Walędziak, Anna

    Journal of clinical medicine

    2022  Volume 11, Issue 23

    Abstract: Introduction: The ratio of cesarean deliveries (CDs) has been increasing worldwide, with a growing problem of cesarean delivery on maternal request (CDMR) and an alarmingly increasing rate of CD in the private sector. There are numerous factors ... ...

    Abstract Introduction: The ratio of cesarean deliveries (CDs) has been increasing worldwide, with a growing problem of cesarean delivery on maternal request (CDMR) and an alarmingly increasing rate of CD in the private sector. There are numerous factors influencing women’s preferences for the mode of delivery and their opinion about shared decision making (SDM). Material and method: The study was designed as an online survey, filled in by 1040 women. The questionnaire included questions about women’s preferences for the mode of delivery, their opinions about CDMR and the process of decision making regarding the mode of delivery. Results: There were no statistically significant differences found between women with a BMI ≤ 25 kg/m2 and >25 kg/m2, nor with a BMI ≤ 30 kg/m2 and >30 kg/m2, on the subject of the preferred method of delivery, and the opinion regarding SDM and CDMR without medical indications. More than 85% of women in all groups, who preferred CD as the mode of delivery, wanted to have CDMR. Conclusion: We have not found obesity and overweight to be a factor influencing women’s preferred mode of delivery, their opinion about SDM and their preference for CDMR without medical indications. However, the sample size of women with morbid obesity with a BMI ≥ 35 kg/m2 was too small for the results to be considered significant in this group, and it will therefore be subject to further studies.
    Language English
    Publishing date 2022-12-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm11237234
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Obesity, Bariatric Surgery and Obstructive Sleep Apnea-A Narrative Literature Review.

    Wyszomirski, Krzysztof / Walędziak, Maciej / Różańska-Walędziak, Anna

    Medicina (Kaunas, Lithuania)

    2023  Volume 59, Issue 7

    Abstract: The purpose of this review was to analyze the available literature on the subject of obesity and obstructive sleep apnea. We searched for available articles for the time period from 2013 to 2023. Obesity is listed as one of the most important health ... ...

    Abstract The purpose of this review was to analyze the available literature on the subject of obesity and obstructive sleep apnea. We searched for available articles for the time period from 2013 to 2023. Obesity is listed as one of the most important health issues. Complications of obesity, with obstructive sleep apnea (OSA) listed among them, are common problems in clinical practice. Obesity is a well-recognized risk factor for OSA, but OSA itself may contribute to worsening obesity. Bariatric surgery is a treatment of choice for severely obese patients, especially with present complications, and remains the only causative treatment for patients with OSA. Though improvement in OSA control in patients after bariatric surgery is well-established knowledge, the complete resolution of OSA is achieved in less than half of them. The determination of subpopulations of patients in whom bariatric surgery would be especially advantageous is an important issue of OSA management. Increasing the potential of non-invasive strategies in obesity treatment requires studies that assess the efficacy and safety of combined methods.
    MeSH term(s) Humans ; Polysomnography ; Obesity/complications ; Obesity/surgery ; Bariatric Surgery/adverse effects ; Sleep Apnea, Obstructive/complications ; Risk Factors ; Obesity, Morbid/complications
    Language English
    Publishing date 2023-07-07
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina59071266
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: The Role of GLP-1, GIP, MCP-1 and IGFBP-7 Biomarkers in the Development of Metabolic Disorders: A Review and Predictive Analysis in the Context of Diabetes and Obesity.

    Jędrysik, Malwina / Wyszomirski, Krzysztof / Różańska-Walędziak, Anna / Grosicka-Maciąg, Emilia / Walędziak, Maciej / Chełstowska, Beata

    Biomedicines

    2024  Volume 12, Issue 1

    Abstract: Metabolic illnesses, including obesity and type 2 diabetes, have become worldwide epidemics that have an effect on public health. Clinical investigations and further exploration of these mechanisms could lead to innovative, effective, and personalized ... ...

    Abstract Metabolic illnesses, including obesity and type 2 diabetes, have become worldwide epidemics that have an effect on public health. Clinical investigations and further exploration of these mechanisms could lead to innovative, effective, and personalized treatment strategies for individuals. It is important to screen biomarkers in previous studies to discover what is missing. Glucagon-like peptide-1's role in insulin secretion and glucose control highlights its diagnostic and therapeutic potential. Glucose-dependent insulinotropic peptide's influence on postprandial satiety and weight management signifies its importance in understanding metabolic processes. Monocyte chemoattractant protein-1's involvement in inflammation and insulin resistance underlines its value as a diagnostic marker. Insulin-like growth factor-binding protein-7's association with insulin sensitivity and kidney function presents it as a potential target for these diseases' management. In validating these biomarkers, it will be easier to reflect pathophysiological processes, and clinicians will be able to better assess disease severity, monitor disease progression, and tailor treatment strategies. The purpose of the study was to elucidate the significance of identifying novel biomarkers for type 2 diabetes mellitus and obesity, which can revolutionize early detection, risk assessment, and personalized treatment strategies. Standard literature searches of PubMed (MEDLINE), EMBASE, and Cochrane Library were conducted in the year 2023 to identify both original RCTs and recent systematic reviews that have explored the importance of identifying novel biomarkers for T2D and obesity. This search produced 1964 results, and then was reduced to randomized controlled trial and systematic reviews, producing 145 results and 44 results, respectively. Researchers have discovered potential associations between type 2 diabetes mellitus and obesity and the biomarkers glucagon-like peptide-1, glucose-dependent insulinotropic peptide, monocyte chemoattractant protein-1, and insulin-like growth factor-binding protein-7. Understanding the role of those biomarkers in disease pathogenesis offers hope for improving diagnostics, personalized treatment, and prevention strategies.
    Language English
    Publishing date 2024-01-11
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines12010159
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Bariatric surgery and menopause.

    Walędziak, Maciej / Różańska-Walędziak, Anna Maria

    Przeglad menopauzalny = Menopause review

    2022  Volume 21, Issue 4, Page(s) 242–245

    Abstract: Introduction: Menopause is a process that affects hormonal levels and metabolic processes in women. The decline in oestrogen levels can predispose to the development of type 2 diabetes mellitus and obesity.: Material and methods: The study group ... ...

    Abstract Introduction: Menopause is a process that affects hormonal levels and metabolic processes in women. The decline in oestrogen levels can predispose to the development of type 2 diabetes mellitus and obesity.
    Material and methods: The study group included 614 women with a history of bariatric surgery, who were divided into 2 groups according to their menopausal status. The purpose of the study was to assess the influence of menopausal status on the effects of bariatric surgery in terms of weight loss.
    Results: The percentage of estimated weight loss (%EWL), total weight loss (TWL), percentage of total weight loss (%TWL), and change in body mass index (BMI) after bariatric surgery are lower in postmenopausal than in premenopausal women.
    Conclusions: Menopause can be considered as a factor influencing the efficacy of bariatric surgery, with lower effects in postmenopausal women.
    Language English
    Publishing date 2022-09-20
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 2596140-8
    ISSN 2299-0038 ; 1643-8876
    ISSN (online) 2299-0038
    ISSN 1643-8876
    DOI 10.5114/pm.2022.116885
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Factors Influencing Polish Women's Preference for the Mode of Delivery and Shared-Decision Making: Has Anything Changed over the Last Decade?

    Walędziak, Maciej / Jodzis, Agnieszka / Różańska-Walędziak, Anna

    Medicina (Kaunas, Lithuania)

    2022  Volume 58, Issue 12

    Abstract: Background and Objectives: Shared-decision making has become an important trend in the problem of women’s preference for the way of delivery. There are different factors influencing women, including obstetric history, culture, religion, family and social ...

    Abstract Background and Objectives: Shared-decision making has become an important trend in the problem of women’s preference for the way of delivery. There are different factors influencing women, including obstetric history, culture, religion, family and social influences. Materials and Methods: The study was designed as an online survey with the aim of acquiring information about women’s knowledge, opinions and preferences about the mode of delivery and the decision-making process. Data were collected from 1175 women in 2010 and 1033 in 2020. Results: A significant increase in the proportion of women who prefer vaginal delivery (VD) was found to be present with an increasing level of education, with the lowest rate in the group with primary education (66.0% in 2010 and 33.3% in 2020) and highest with medical education—86.3% in 2010 and 69.3% in 2020 (p < 0.05). This trend existed both in 2010 and 2020; however, the proportion of women who preferred VD has decreased over the last decade in all groups, and even two-fold in the primary education group. No significant correlation was found between a history of previous delivery and the preference of the way of delivery, decision-making or paid cesarean delivery on maternal request (CDMR). A history of VD significantly reduced the preference for having a cesarean delivery, with only 6.9% of women in 2010 with a history of VD, and 8.9% in 2020 having preferred a cesarean delivery. In 2010, 34.9% of women with a history of cesarean section (CS) only, compared to 6.9% of women with a history VD only, had preference for CS with, respectively, 36.4% vs. 5.8% in 2020. Conclusions: As the proportion of women who prefer cesarean delivery has significantly increased over the last decade, we should emphasize the importance of educating women about the advantages and disadvantages of vaginal and cesarean delivery. The patient’s preference should always be discussed with the obstetrician and the medical indications explained.
    MeSH term(s) Pregnancy ; Female ; Humans ; Cesarean Section ; Poland ; Surveys and Questionnaires ; Educational Status ; Decision Making ; Patient Preference
    Language English
    Publishing date 2022-12-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina58121782
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Gynecological Fistulae-Has Anything Changed in the Diagnosis and Treatment over the Last Decade? A Narrative Literature Review.

    Misiak, Marek / Dworak, Michalina / Wyszomirska, Małgorzata / Kurt, Maria / Walędziak, Maciej / Różańska-Walędziak, Anna

    Medicina (Kaunas, Lithuania)

    2023  Volume 59, Issue 8

    Abstract: Gynecological fistulae are a rare but severe complication of radiation therapy, pelvic surgery, prolonged labor, cesarean deliveries, or inflammatory bowel diseases. A gynecological fistula is an abnormal pathway formed between the urinary and ... ...

    Abstract Gynecological fistulae are a rare but severe complication of radiation therapy, pelvic surgery, prolonged labor, cesarean deliveries, or inflammatory bowel diseases. A gynecological fistula is an abnormal pathway formed between the urinary and gynecological tract, most commonly located between the urinary bladder and vagina. Vesico-uterine and vesicovaginal fistulae are an important health issue, common in women of reproductive age in developing countries with limited access to obstetrical care. Various surgical techniques have been described for VVF repair, depending on the location, severity, and cause of the fistula and the surgeon's experience. The purpose of our review was to evaluate the present state of knowledge about the prevalence and treatment of gynecological fistulae. The PubMed scientific database was searched for original articles on the subject of gynecological fistulae that had been published between 2013 and 2023.
    MeSH term(s) Pregnancy ; Female ; Humans ; Fistula ; Obstetrics ; Urinary Bladder ; Cesarean Section ; Databases, Factual
    Language English
    Publishing date 2023-08-12
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina59081455
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Nutritional Implications of Bariatric Surgery on Pregnancy Management-A Narrative Review of the Literature.

    Różańska-Walędziak, Anna / Walędziak, Maciej / Mierzejewska, Anna / Skopińska, Ewa / Jędrysik, Malwina / Chełstowska, Beata

    Medicina (Kaunas, Lithuania)

    2023  Volume 59, Issue 10

    Abstract: One in three women of reproductive age is obese. The mainstay treatment for obesity is bariatric surgery, and the following weight reduction results in a decrease in pregnancy adverse effects, including gestational diabetes mellitus, pregnancy-induced ... ...

    Abstract One in three women of reproductive age is obese. The mainstay treatment for obesity is bariatric surgery, and the following weight reduction results in a decrease in pregnancy adverse effects, including gestational diabetes mellitus, pregnancy-induced hypertension, and macrosomia. However, nutritional and vitamin deficiencies due to changes in the gastrointestinal tract after bariatric surgery are associated with an increase in the risk of fetal growth retardation and small for gestational-age neonates. The purpose of this review was to analyze the available recent literature on the subject of the management of pregnancy after bariatric surgery. We searched for available articles from 2007 to 2023 and chose articles of the greatest scientific and clinical value. Micronutrient, vitamin, and protein supplementation is recommended in the prenatal period and throughout the pregnancy. It is advised that pregnant women with a history of bariatric surgery should be provided with regular specialist dietary care. There is still a lack of recommendations about the optimum gestational weight gain after different types of bariatric surgery and for patients of different metabolic statuses. Women of reproductive age undergoing bariatric procedures should be provided with appropriate counseling about adequate contraception, the recommended time-to-conception interval, and the positive and negative influence of bariatric surgery on perinatal outcomes.
    MeSH term(s) Infant, Newborn ; Pregnancy ; Female ; Humans ; Pregnancy Complications/etiology ; Bariatric Surgery/adverse effects ; Bariatric Surgery/methods ; Obesity/complications ; Obesity/surgery ; Diabetes, Gestational ; Hypertension, Pregnancy-Induced ; Fetal Growth Retardation
    Language English
    Publishing date 2023-10-19
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina59101864
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Intrapartum Analgesia-Have Women's Preferences Changed over the Last Decade?

    Jodzis, Agnieszka / Walędziak, Maciej / Czajkowski, Krzysztof / Różańska-Walędziak, Anna

    Medicina (Kaunas, Lithuania)

    2022  Volume 58, Issue 1

    Abstract: Background: Global access to social media has supposedly changed women's awareness about the pharmacological and alternative methods of pain relief during vaginal delivery. The purpose of the study was to analyze changes in women's preference and ... ...

    Abstract Background: Global access to social media has supposedly changed women's awareness about the pharmacological and alternative methods of pain relief during vaginal delivery. The purpose of the study was to analyze changes in women's preference and opinion about different forms of labor analgesia over the past decade.
    Materials and methods: The study was designed as an anonymous survey with questions about women's knowledge and preference of different forms of pain relief in labor. The survey was conducted in 2010 and 2020, with data collected from 1175 women in 2010 and 1033 in 2020.
    Results: There were no differences between 2010 and 2020 in the proportion of women who wanted to receive analgesia in labor, at, respectively 67.9% of women in 2010 and 73.9% in 2020. About 50% of women chose epidural analgesia as the only efficacious method of pain relief in labor both in 2010 and 2020. There were no differences between the two time-points in the distribution of chosen methods of pain relief. In total, 92.3% of women in 2010 and 94.9% in 2020 thought that they should have the possibility of independent choice of analgesia method before the delivery (
    Conclusions: A high proportion of Polish women choose EDA over other pharmacological and nonpharmacological methods of pain relief in labor, and this preference has not changed over the last decade. Increasing women's knowledge about different methods of intrapartum pain relief may lead to wider use of nonpharmacological methods of pain relief.
    MeSH term(s) Analgesia, Epidural ; Female ; Humans ; Labor, Obstetric ; Pain ; Pregnancy ; Surveys and Questionnaires
    Language English
    Publishing date 2022-01-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina58010087
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: A Decade of Wishes-Changes in Maternal Preference of the Mode of Delivery among Polish Women over the Last Decade.

    Jodzis, Agnieszka / Walędziak, Maciej / Czajkowski, Krzysztof / Różańska-Walędziak, Anna

    Medicina (Kaunas, Lithuania)

    2021  Volume 57, Issue 6

    Abstract: Background and Objectives: ...

    Abstract Background and Objectives:
    MeSH term(s) Cesarean Section ; Family ; Female ; Humans ; Patient Preference ; Poland ; Pregnancy ; Surveys and Questionnaires
    Language English
    Publishing date 2021-06-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina57060572
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Intrapartum Analgesia—Have Women’s Preferences Changed over the Last Decade?

    Agnieszka Jodzis / Maciej Walędziak / Krzysztof Czajkowski / Anna Różańska-Walędziak

    Medicina, Vol 58, Iss 87, p

    2022  Volume 87

    Abstract: Background: Global access to social media has supposedly changed women’s awareness about the pharmacological and alternative methods of pain relief during vaginal delivery. The purpose of the study was to analyze changes in women’s preference and opinion ...

    Abstract Background: Global access to social media has supposedly changed women’s awareness about the pharmacological and alternative methods of pain relief during vaginal delivery. The purpose of the study was to analyze changes in women’s preference and opinion about different forms of labor analgesia over the past decade. Materials and methods: The study was designed as an anonymous survey with questions about women’s knowledge and preference of different forms of pain relief in labor. The survey was conducted in 2010 and 2020, with data collected from 1175 women in 2010 and 1033 in 2020. Results: There were no differences between 2010 and 2020 in the proportion of women who wanted to receive analgesia in labor, at, respectively 67.9% of women in 2010 and 73.9% in 2020. About 50% of women chose epidural analgesia as the only efficacious method of pain relief in labor both in 2010 and 2020. There were no differences between the two time-points in the distribution of chosen methods of pain relief. In total, 92.3% of women in 2010 and 94.9% in 2020 thought that they should have the possibility of independent choice of analgesia method before the delivery ( p < 0.04). Conclusions: A high proportion of Polish women choose EDA over other pharmacological and nonpharmacological methods of pain relief in labor, and this preference has not changed over the last decade. Increasing women’s knowledge about different methods of intrapartum pain relief may lead to wider use of nonpharmacological methods of pain relief.
    Keywords vaginal delivery ; epidural analgesia ; pain relief in labor ; maternal preference ; shared decision making ; Medicine (General) ; R5-920
    Subject code 300
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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