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  1. Book: Basic cell culture protocols

    Helgason, Cheryl D.

    (Methods in molecular biology ; 946 ; Springer protocols)

    2013  

    Author's details ed. by Cheryl D. Helgason
    Series title Methods in molecular biology ; 946
    Springer protocols
    Collection
    Keywords Cells, Cultured ; Cytological Techniques ; Zellkultur ; Gewebekultur
    Subject Gewebezüchtung ; Zelle ; Zellzüchtung
    Language English
    Size XIV, 550 S. : Ill., graph. Darst.
    Edition 4. ed.
    Publisher Humana Press
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT017485917
    ISBN 978-1-62703-127-1 ; 9781627031288 ; 1-62703-127-8 ; 1627031286
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2012 A 4569 order for loan Magazin

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  2. Book ; Audio / Video: Basic cell culture protocols

    Helgason, Cheryl D.

    ([Methods in molecular biology ; 290])

    2005  

    Author's details ed. by Cheryl D. Helgason
    Series title [Methods in molecular biology ; 290]
    Methods in molecular biology
    Collection Methods in molecular biology
    Keywords Cells, Cultured ; Cytological Techniques ; Zellkultur ; Gewebekultur
    Subject Gewebezüchtung ; Zelle ; Zellzüchtung
    Language English
    Size 1 CD-ROM, 12 cm
    Edition 3. ed.
    Publisher Humana Press
    Publishing place Totowa, NJ
    Publishing country United States
    Document type Book ; Audio / Video
    Remark Auf Multimedia-PC (Lesesaal) installiert
    HBZ-ID HT014446110
    ISBN 1-59259-838-2 ; 978-1-59259-838-0
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    LCDisk 237 on loan 0 Vormerkungen

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  3. Book: Basic cell culture protocols

    Helgason, Cheryl D.

    (Methods in molecular biology ; 290)

    2005  

    Author's details ed. by Cheryl D. Helgason
    Series title Methods in molecular biology ; 290
    Collection
    Keywords Cells, Cultured ; Cytological Techniques ; Zellkultur ; Gewebekultur
    Subject Gewebezüchtung ; Zelle ; Zellzüchtung
    Language English
    Size XII, 371 S. : Ill., graph. Darst.
    Edition 3. ed.
    Publisher Humana Press
    Publishing place Totowa, NJ
    Publishing country United States
    Document type Book
    HBZ-ID HT014052742
    ISBN 1-58829-545-1 ; 1-58829-284-3 ; 978-1-58829-545-3 ; 978-1-58829-284-1
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    058/1736 available for loan (reading room) Freihandmagazin (U1)

    Order via subito

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  4. Book: Basic cell culture protocols

    Helgason, Cheryl D.

    (Methods in molecular biology ; 290)

    2005  

    Author's details ed. by Cheryl D. Helgason
    Series title Methods in molecular biology ; 290
    Collection
    Keywords Cells, Cultured ; Cytological Techniques ; Zellkultur ; Gewebekultur
    Subject Gewebezüchtung ; Zelle ; Zellzüchtung
    Language English
    Size XII, 371 S. : Ill., graph. Darst.
    Edition 3. ed.
    Publisher Humana Press
    Publishing place Totowa, NJ
    Publishing country United States
    Document type Book
    HBZ-ID HT014052742
    ISBN 1-58829-545-1 ; 1-58829-284-3 ; 978-1-58829-545-3 ; 978-1-58829-284-1
    Database Catalogue ZB MED Medicine, Health

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    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2005 A 3258 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Book ; Audio / Video: Basic cell culture protocols

    Helgason, Cheryl D.

    ([Methods in molecular biology ; 290])

    2005  

    Author's details ed. by Cheryl D. Helgason
    Series title [Methods in molecular biology ; 290]
    Methods in molecular biology
    Collection Methods in molecular biology
    Keywords Cells, Cultured ; Cytological Techniques ; Zellkultur ; Gewebekultur
    Subject Gewebezüchtung ; Zelle ; Zellzüchtung
    Language English
    Size 1 CD-ROM, 12 cm
    Edition 3. ed.
    Publisher Humana Press
    Publishing place Totowa, NJ
    Publishing country United States
    Document type Book ; Audio / Video
    Remark Auf Multimedia-PC (Lesesaal) installiert
    HBZ-ID HT014446110
    ISBN 1-59259-838-2 ; 978-1-59259-838-0
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2005 MO 561 not available for loan Magazin
    Auf Muiltimedia-PC (Lesesaal) installiert

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  6. Article: Iodinated contrast for patients with chronic kidney disease-writing on the wall or free for all?

    Helgason, Dadi / Sigurdsson, Martin I

    Quantitative imaging in medicine and surgery

    2021  Volume 11, Issue 2, Page(s) 876–878

    Language English
    Publishing date 2021-02-02
    Publishing country China
    Document type Editorial ; Comment
    ZDB-ID 2653586-5
    ISSN 2223-4306 ; 2223-4292
    ISSN (online) 2223-4306
    ISSN 2223-4292
    DOI 10.21037/qims-2020-27
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Brassica napus Bacterial Assembly Processes Vary with Plant Compartment and Growth Stage but Not between Lines.

    Bell, Jennifer K / Mamet, Steven D / Helgason, Bobbi / Siciliano, Steven D

    Applied and environmental microbiology

    2022  Volume 88, Issue 10, Page(s) e0027322

    Abstract: Holobiont bacterial community assembly processes are an essential element to understanding the plant microbiome. To elucidate these processes, leaf, root, and rhizosphere samples were collected from eight lines of Brassica napus in Saskatchewan over the ... ...

    Abstract Holobiont bacterial community assembly processes are an essential element to understanding the plant microbiome. To elucidate these processes, leaf, root, and rhizosphere samples were collected from eight lines of Brassica napus in Saskatchewan over the course of 10 weeks. We then used ecological null modeling to disentangle the community assembly processes over the growing season in each plant part. The root was primarily dominated by stochastic community assembly processes, which is inconsistent with previous studies that suggest of a highly selective root environment. Leaf assembly processes were primarily stochastic as well. In contrast, the rhizosphere was a highly selective environment. The dominant rhizosphere selection process leads to more similar communities. Assembly processes in all plant compartments were dependent on plant growth stage with little line effect on community assembly. The foundations of assembly in the leaf were due to the harsh environment, leading to dominance of stochastic effects, whereas the stochastic effects in the root interior likely arise due to competitive exclusion or priority effects. Engineering canola microbiomes should occur during periods of strong selection assuming strong selection could promote beneficial bacteria. For example, engineering the microbiome to resist pathogens, which are typically aerially born, should focus on the flowering period, whereas microbiomes to enhance yield should likely be engineered postflowering as the rhizosphere is undergoing strong selection.
    MeSH term(s) Brassica napus/microbiology ; Plant Breeding ; Plant Roots/microbiology ; Rhizosphere ; Soil Microbiology
    Language English
    Publishing date 2022-04-28
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 223011-2
    ISSN 1098-5336 ; 0099-2240
    ISSN (online) 1098-5336
    ISSN 0099-2240
    DOI 10.1128/aem.00273-22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 201: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Refracture and mortality risk in the elderly with osteoporotic fractures: the AGES-Reykjavik study.

    Praveen, Anitha D / Aspelund, Thor / Ferguson, Stephen J / Sigurðsson, Sigurður / Guðnason, Vilmundur / Pálsson, Halldór / Matchar, David / Helgason, Benedikt

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

    2024  

    Abstract: There is imminent refracture risk in elderly individuals for up to six years, with a decline thereafter except in women below 75 who face a constant elevated risk. Elderly men with fractures face the highest mortality risk, particularly those with hip ... ...

    Abstract There is imminent refracture risk in elderly individuals for up to six years, with a decline thereafter except in women below 75 who face a constant elevated risk. Elderly men with fractures face the highest mortality risk, particularly those with hip and vertebral fractures. Targeted monitoring and treatment strategies are recommended.
    Purpose: Current management and interventions for osteoporotic fractures typically focus on bone mineral density loss, resulting in suboptimal evaluation of fracture risk. The aim of the study is to understand the progression of fractures to refractures and mortality in the elderly using multi-state models to better target those at risk.
    Methods: This prospective, observational study analysed data from the AGES-Reykjavik cohort of Icelandic elderly, using multi-state models to analyse the evolution of fractures into refractures and mortality, and to estimate the probability of future events in subjects based on prognostic factors.
    Results: At baseline, 4778 older individuals aged 65 years and older were included. Elderly men, and elderly women above 80 years of age, had a distinct imminent refracture risk that lasted between 2-6 years, followed by a sharp decline. However, elderly women below 75 continued to maintain a nearly constant refracture risk profile for ten years. Hip (30-63%) and vertebral (24-55%) fractures carried the highest 5-year mortality burden for elderly men and women, regardless of age, and for elderly men over 80, lower leg fractures also posed a significant mortality risk.
    Conclusion: The risk of refracture significantly increases in the first six years following the initial fracture. Elderly women, who experience fractures at a younger age, should be closely monitored to address their long-term elevated refracture risk. Elderly men, especially those with hip and vertebral fractures, face substantial mortality risk and require prioritized monitoring and treatment.
    Language English
    Publishing date 2024-04-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 1064892-6
    ISSN 1433-2965 ; 0937-941X
    ISSN (online) 1433-2965
    ISSN 0937-941X
    DOI 10.1007/s00198-024-07096-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3163: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Ceramics in total disc replacements: A scoping review.

    Kölle, Lucia / Ignasiak, Dominika / Ferguson, Stephen J / Helgason, Benedikt

    Clinical biomechanics (Bristol, Avon)

    2022  Volume 100, Page(s) 105796

    Abstract: Background: Ceramics are used in Total Disc Replacements (1) in articulating surfaces for their wear resistance and biocompatibility and (2) on endplates to promote osseointegration. They furthermore exhibit MRI and CT compatibility. These properties ... ...

    Abstract Background: Ceramics are used in Total Disc Replacements (1) in articulating surfaces for their wear resistance and biocompatibility and (2) on endplates to promote osseointegration. They furthermore exhibit MRI and CT compatibility. These properties address main challenges associated with non-ceramic Total Disc Replacements i.e. wear, migration and postoperative imaging. While brittleness of ceramics caused fear of fracture in the past, improvements of ceramic materials were made and considerable clinical experience with ceramic Total Disc Replacements was gained. This review aims to assess the evidence on the use of ceramics in Total Disc Replacements and compare safety and effectiveness of ceramic Total Disc Replacements to spinal fusion and Total Disc Replacements in general.
    Methods: We conducted a scoping review on the use of ceramics in Total Disc Replacements using Scopus, Web of Science and PubMed. The review includes 36 clinical, ex vivo and nonhuman in vivo, tribological and mechanical studies and case reports.
    Findings: Ceramics are used in cervical Total Disc Replacements, with safety and efficacy confirmed in clinical studies, with up to 10 and 3.3 years follow-up, for articulation and osseointegration applications, respectively. Clinical evidence shows that ceramic Total Disc Replacements (alike non-ceramic ones) restore segmental motion and result in non-inferior and possibly superior outcomes to spinal fusion. In vivo studies show osseointegration comparable to non-ceramic devices. Tribological studies suggest appropriate wear properties.
    Interpretation: We found no indications of systematic problems with the use of ceramics in Total Disc Replacements. Ceramics are suitable materials for Total Disc Replacements.
    MeSH term(s) Humans ; Total Disc Replacement ; Research Design
    Language English
    Publishing date 2022-10-13
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 632747-3
    ISSN 1879-1271 ; 0268-0033
    ISSN (online) 1879-1271
    ISSN 0268-0033
    DOI 10.1016/j.clinbiomech.2022.105796
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2876: Show issues Location:
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  10. Article ; Online: CT image-based biomarkers for opportunistic screening of osteoporotic fractures: a systematic review and meta-analysis.

    Praveen, Anitha D / Sollmann, Nico / Baum, Thomas / Ferguson, Stephen J / Benedikt, Helgason

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

    2024  

    Abstract: The use of opportunistic computed tomography (CT) image-based biomarkers may be a low-cost strategy for screening older individuals at high risk for osteoporotic fractures and populations that are not sufficiently targeted. This review aimed to assess ... ...

    Abstract The use of opportunistic computed tomography (CT) image-based biomarkers may be a low-cost strategy for screening older individuals at high risk for osteoporotic fractures and populations that are not sufficiently targeted. This review aimed to assess the discriminative ability of image-based biomarkers derived from existing clinical routine CT scans for hip, vertebral, and major osteoporotic fracture prediction. A systematic search in PubMed MEDLINE, Embase, Cochrane, and Web of Science was conducted from the earliest indexing date until July 2023. The evaluation of study quality was carried out using a modified Quality Assessment Tool for Diagnostic Accuracy Studies (QUADAS-2) checklist. The primary outcome of interest was the area under the curve (AUC) and its corresponding 95% confidence intervals (CIs) obtained for four main categories of biomarkers: areal bone mineral density (BMD), image attenuation, volumetric BMD, and finite element (FE)-derived biomarkers. The meta-analyses were performed using random effects models. Sixty-one studies were included in this review, among which 35 were synthesized in a meta-analysis and the remaining articles were qualitatively synthesized. In comparison to the pooled AUC of areal BMD (0.73 [95% CI 0.71-0.75]), the pooled AUC values for predicting osteoporotic fractures for FE-derived parameters (0.77 [95% CI 0.72-0.81]; p < 0.01) and volumetric BMD (0.76 [95% CI 0.71-0.81]; p < 0.01) were significantly higher, but there was no significant difference with the pooled AUC for image attenuation (0.73 [95% CI 0.66-0.79]; p = 0.93). Compared to areal BMD, volumetric BMD and FE-derived parameters may provide a significant improvement in the discrimination of osteoporotic fractures using opportunistic CT assessments.
    Language English
    Publishing date 2024-02-14
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1064892-6
    ISSN 1433-2965 ; 0937-941X
    ISSN (online) 1433-2965
    ISSN 0937-941X
    DOI 10.1007/s00198-024-07029-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3163: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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