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  1. Article ; Online: Groundbreaking outpatient activity in medical entomology in France: An eight-year experience in a french university hospital.

    Sevestre, Jacques / Marty, Pierre / Hubiche, Thomas / Pomares, Christelle / Delaunay, Pascal

    Infectious diseases now

    2023  Volume 53, Issue 7, Page(s) 104728

    Abstract: Introduction: Arthropods are known to impair human health in various manners, acting as infectious disease vectors, or as simple nuisances. Even though considerable research is being produced in medical entomology, no reports on patient management in ... ...

    Abstract Introduction: Arthropods are known to impair human health in various manners, acting as infectious disease vectors, or as simple nuisances. Even though considerable research is being produced in medical entomology, no reports on patient management in clinical entomology units are available in the literature.
    Patients and methods: We retrospectively surveyed all the records from patients having consulted in our outpatient clinical entomology unit in Nice University Hospital from 2012 to 2020. For each patient, physical examination findings and treatment data were analyzed.
    Results: A total of 518 patients were analyzed in this study. Most were diagnosed with arthropod infestation (55.8%), the most common being Sarcoptes scabiei (35%), bedbugs (23%), Pyemotes dermatitis (17.6%) and flea infestation (15.9%). Along with symptomatic treatments, targeted environmental measures could be proposed for infested patients. For many of our patients, on the other hand, active infestation was ruled out.
    Conclusion: Given today's lack of expertise in medical entomology, we advocate for the creation of medical entomology units in university hospitals, not only allowing fair and proportionate multidisciplinary management of patients in whom arthropod infestation is suspected, but also generating cost savings.
    Language English
    Publishing date 2023-06-08
    Publishing country France
    Document type Journal Article
    ISSN 2666-9919
    ISSN (online) 2666-9919
    DOI 10.1016/j.idnow.2023.104728
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  2. Article ; Online: Superficial fungal infections in the south of France-is fusariosis the next emergent onychopathy?

    Landreau, Anne / Simon, Loïc / Delaunay, Pascal / Pomares, Christelle / Hasseine, Lilia

    Medical mycology

    2023  Volume 61, Issue 2

    Abstract: In France, onychomycoses represent about 30% of superficial mycoses seen by dermatologists. In recent years, an increased number of mycoses have been observed due to non-dermatophytic moulds. The purpose of this study was to evaluate the epidemiological ... ...

    Abstract In France, onychomycoses represent about 30% of superficial mycoses seen by dermatologists. In recent years, an increased number of mycoses have been observed due to non-dermatophytic moulds. The purpose of this study was to evaluate the epidemiological profile of identified superficial fungal infections in the Laboratory of Parasitology-Mycology of the University Hospital of Nice over a 2-year period. A retrospective study was performed from the nail, skin, and scalp samples of patients analyzed from January 2018 to December 2019. In this study, 3074 samples (54.2% nails, 39.7% skin, and 6.1% scalp) were analyzed representing 1922 patients. Among them, 809 (42.1%) patients were sampled by dermatologists and 1113 (57.9%) were sampled by our experts in the clinical unit of the University Hospital of Nice. In total, 1159 (37.7%) samples had a positive culture (1195 strains identified) including 712 (59.6%) dermatophytes, 345 (28.9%) yeasts, and 138 (11.5%) other filamentous moulds. Trichophyton rubrum was the main dermatophyte (563; 47.1%) followed by T. interdigitale (84; 7.0%), and T. soudanense (25; 2.1%). Yeasts were mostly represented by Candida albicans (155; 13.0%). Among the other moulds, Fusarium sp. was the most isolated (61; 5.1%). Dermatophytes stay predominant in superficial fungal infections where the anthropophilic species T. rubrum was found in almost half of the positive cultures. Interestingly, moulds represented an important part of infections in our population. This study highlights the increasing share of Fusarium sp. superficial fungal infection in our patients' population, perhaps requiring a major therapeutic adaptation in the years to come.
    MeSH term(s) Animals ; Fusariosis/epidemiology ; Fusariosis/veterinary ; Retrospective Studies ; Onychomycosis/epidemiology ; Onychomycosis/microbiology ; Onychomycosis/veterinary ; Dermatomycoses/epidemiology ; Dermatomycoses/microbiology ; Dermatomycoses/veterinary ; Yeasts ; Fusarium ; France/epidemiology
    Language English
    Publishing date 2023-02-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 1421796-x
    ISSN 1460-2709 ; 1369-3786
    ISSN (online) 1460-2709
    ISSN 1369-3786
    DOI 10.1093/mmy/myad015
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  3. Article ; Online: Photo Quiz: A 54-Year-Old Congolese Woman with Knee Pain.

    Costa, Damien / Rottenberg, Pascal / Toure, Emmanuel / Delaunay, Pascal / Favennec, Loic / Gargala, Gilles

    Journal of clinical microbiology

    2020  Volume 59, Issue 1

    Language English
    Publishing date 2020-12-17
    Publishing country United States
    Document type Editorial
    ZDB-ID 390499-4
    ISSN 1098-660X ; 0095-1137
    ISSN (online) 1098-660X
    ISSN 0095-1137
    DOI 10.1128/JCM.00389-20
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  4. Article ; Online: Answer to January 2021 Photo Quiz.

    Costa, Damien / Rottenberg, Pascal / Toure, Emmanuel / Delaunay, Pascal / Favennec, Loic / Gargala, Gilles

    Journal of clinical microbiology

    2020  Volume 59, Issue 1

    Language English
    Publishing date 2020-12-17
    Publishing country United States
    Document type Editorial
    ZDB-ID 390499-4
    ISSN 1098-660X ; 0095-1137
    ISSN (online) 1098-660X
    ISSN 0095-1137
    DOI 10.1128/JCM.00390-20
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  5. Article ; Online: Painful Awakening due to

    Simon, Loïc / Delaunay, Pascal / Marty, Pierre

    The American journal of tropical medicine and hygiene

    2020  Volume 103, Issue 4, Page(s) 1352

    MeSH term(s) Aged ; Animals ; Humans ; Hymenoptera/classification ; Hymenoptera/physiology ; Insect Bites and Stings/pathology ; Male ; Pain/etiology
    Language English
    Publishing date 2020-12-02
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2942-7
    ISSN 1476-1645 ; 0002-9637
    ISSN (online) 1476-1645
    ISSN 0002-9637
    DOI 10.4269/ajtmh.20-0188
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  6. Article ; Online: Bed bug bites.

    Delaunay, Pascal / Benzaquen, Michael / Berenger, Jean-Michel / Parola, Philippe

    Dermatologic therapy

    2020  Volume 33, Issue 6, Page(s) e14341

    MeSH term(s) Animals ; Bedbugs ; Humans
    Language English
    Publishing date 2020-10-07
    Publishing country United States
    Document type Letter
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.14341
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  7. Article ; Online: Human travel and traveling bedbugs.

    Delaunay, Pascal

    Journal of travel medicine

    2012  Volume 19, Issue 6, Page(s) 373–379

    Abstract: Background: A dramatic increase of reported bedbug (Cimex lectularius and Cimex hemipterus) infestations has been observed worldwide over the past decade. Bedbug infestations have also been detected across a wide range of travel accommodations, ... ...

    Abstract Background: A dramatic increase of reported bedbug (Cimex lectularius and Cimex hemipterus) infestations has been observed worldwide over the past decade. Bedbug infestations have also been detected across a wide range of travel accommodations, regardless of their comfort and hygiene levels. Travelers are increasingly exposed to the risks of bedbug bites, infestation of personal belongings, and subsequent contamination of newly visited accommodations and their homes.
    Methods: We searched Medline publications via the PubMed database. National bedbug recommendations, textbooks, newspapers, and Centers for Disease Control websites were also searched manually.
    Discussion: To detect infested sites, avoid or limit bedbug bites, and reduce the risk of contaminating one's belongings and home, bedbug biology and ecology must be understood. A detailed search of their most classic hiding niches is a key to finding adult bedbugs, nymphs, eggs, and feces or traces of blood from crushed bedbugs. Locally, bedbugs move by active displacement to feed (bite) during the night. Bed, mattress, sofa, and/or curtains are the most frequently infested places. If you find bedbugs, change your room or, even better, the hotel. Otherwise, travelers should follow recommendations for avoiding bedbugs and their bites during the night and apply certain simple rules to avoid infesting other sites or their home.
    Conclusion: Travelers exposed to bedbugs can minimize the risks of bites and infestation of their belongings, and must also do their civic duty to avoid contributing to the subsequent contamination of other hotels and, finally, home.
    MeSH term(s) Animals ; Bedbugs/classification ; Bedbugs/physiology ; Environmental Health ; Humans ; Hygiene/standards ; Insect Bites and Stings/epidemiology ; Insect Bites and Stings/etiology ; Insect Bites and Stings/physiopathology ; Insect Bites and Stings/prevention & control ; Insect Control/methods ; Insect Control/standards ; Public Facilities/standards ; Travel
    Language English
    Publishing date 2012-12
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1212504-0
    ISSN 1708-8305 ; 1195-1982
    ISSN (online) 1708-8305
    ISSN 1195-1982
    DOI 10.1111/j.1708-8305.2012.00653.x
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  8. Article ; Online: Current evidences of the efficacy of mosquito mass-trapping interventions to reduce Aedes aegypti and Aedes albopictus populations and Aedes-borne virus transmission.

    Jaffal, Ali / Fite, Johanna / Baldet, Thierry / Delaunay, Pascal / Jourdain, Frédéric / Mora-Castillo, Ronald / Olive, Marie-Marie / Roiz, David

    PLoS neglected tropical diseases

    2023  Volume 17, Issue 3, Page(s) e0011153

    Abstract: Background: Over the past decades, several viral diseases transmitted by Aedes mosquitoes-dengue, chikungunya, Zika-have spread outside of tropical areas. To limit the transmission of these viruses and preserve human health, the use of mosquito traps ... ...

    Abstract Background: Over the past decades, several viral diseases transmitted by Aedes mosquitoes-dengue, chikungunya, Zika-have spread outside of tropical areas. To limit the transmission of these viruses and preserve human health, the use of mosquito traps has been developed as a complement or alternative to other vector control techniques. The objective of this work was to perform a systematic review of the existing scientific literature to assess the efficacy of interventions based on adult mosquito trap to control Aedes population densities and the diseases they transmit worldwide.
    Methods and findings: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, a systematic review was conducted using the PubMed and Scopus databases. Among the 19 selected papers, lethal ovitraps were used in 16 studies, host-seeking female traps in 3 studies. Furthermore, 16 studies focused on the control of Ae. aegypti. Our review showed great heterogeneity in the indicators used to assess trap efficacy: e.g., the number of host-seeking females, the number of gravid females, the proportion of positive containers, the viral infection rate in female mosquitoes or serological studies in residents. Regardless of the type of studied traps, the results of various studies support the efficacy of mass trapping in combination with classical integrated vector control in reducing Aedes density. More studies with standardized methodology, and indicators are urgently needed to provide more accurate estimates of their efficacy.
    Conclusions: This review highlights gaps in the demonstration of the efficacy of mass trapping of mosquitoes in reducing viral transmission and disease. Thus, further large-scale cluster randomized controlled trials conducted in endemic areas and including epidemiological outcomes are needed to establish scientific evidence for the reduction of viral transmission risk by mass trapping targeting gravid and/or host-seeking female mosquitoes.
    MeSH term(s) Adult ; Animals ; Female ; Humans ; Aedes ; Mosquito Vectors ; Mosquito Control/methods ; Zika Virus ; Zika Virus Infection
    Language English
    Publishing date 2023-03-06
    Publishing country United States
    Document type Systematic Review ; Journal Article
    ZDB-ID 2429704-5
    ISSN 1935-2735 ; 1935-2735
    ISSN (online) 1935-2735
    ISSN 1935-2735
    DOI 10.1371/journal.pntd.0011153
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  9. Article ; Online: Asymptomatic Leishmania infantum infection in dogs and dog owners in an endemic area in southeast France.

    Hide, Mallorie / Michel, Gregory / Legueult, Kevin / Pin, Raphaelle / Leonard, Susana / Simon, Loïc / Bañuls, Anne-Laure / Delaunay, Pascal / Marty, Pierre / Pomares, Christelle

    Parasite (Paris, France)

    2024  Volume 31, Page(s) 16

    Abstract: The prevalence of asymptomatic leishmaniasis in dogs and their owners in the main endemic areas of France has not been studied to date. The objective of this study was to quantify asymptomatic Leishmania infantum infection in southeast France in healthy ... ...

    Title translation Infection asymptomatique à Leishmania infantum chez les chiens et propriétaires de chiens dans une zone endémique du sud-est de la France.
    Abstract The prevalence of asymptomatic leishmaniasis in dogs and their owners in the main endemic areas of France has not been studied to date. The objective of this study was to quantify asymptomatic Leishmania infantum infection in southeast France in healthy people and their dogs using molecular and serological screening techniques. We examined the presence of parasitic DNA using specific PCR targeting kinetoplast DNA (kDNA) and specific antibodies by serology (ELISA for dogs and Western blot for humans) among immunocompetent residents and their dogs in the Alpes-Maritimes. Results from 343 humans and 607 dogs were included. 46.9% (n = 161/343) of humans and 18.3% (n = 111/607) of dogs were PCR positive; 40.2% of humans (n = 138/343) and 9.9% of dogs (n = 60/607) were serology positive. Altogether, 66.2% of humans (n = 227) and 25.7% of dogs (n = 156) had positive serologies and/or positive PCR test results. Short-haired dogs were more frequently infected (71.8%, n = 112) than long-haired dogs (12.2%, n = 19) (p = 0.043). Dogs seemed to be more susceptible to asymptomatic infection according to their breed types (higher infection rates in scenthounds, gun dogs and herding dogs) (p = 0.04). The highest proportion of dogs and human asymptomatic infections was found in the Vence Region, corresponding to 28.2% (n = 20/71) of dogs and 70.5% (n = 31/44) of humans (4.5/100,000 people). In conclusion, the percentage of infections in asymptomatic humans is higher than in asymptomatic dogs in the studied endemic area. It is questionable whether asymptomatic infection in humans constitutes a risk factor for dogs.
    MeSH term(s) Humans ; Dogs ; Animals ; Leishmania infantum/genetics ; Asymptomatic Infections/epidemiology ; Blotting, Western ; Breeding ; DNA, Kinetoplast ; France/epidemiology
    Chemical Substances DNA, Kinetoplast
    Language English
    Publishing date 2024-03-26
    Publishing country France
    Document type Journal Article
    ZDB-ID 1187629-3
    ISSN 1776-1042 ; 1252-607X
    ISSN (online) 1776-1042
    ISSN 1252-607X
    DOI 10.1051/parasite/2024019
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  10. Article ; Online: Corrigendum to 'Comparison of continuous with single-injection regional analgesia on patient experience after ambulatory orthopaedic surgery: a randomised multicentre trial' (Br J Anaesth 2022; 129: 435-44).

    Maurice Szamburski, Axel / Grillo, Philippe / Cuvillon, Philippe / Gazeau, Thierry / Delaunay, Laurent / Auquier, Pascal / Bringuier, Sophie / Capdevila, Xavier

    British journal of anaesthesia

    2022  

    Language English
    Publishing date 2022-10-22
    Publishing country England
    Document type Published Erratum
    ZDB-ID 80074-0
    ISSN 1471-6771 ; 0007-0912
    ISSN (online) 1471-6771
    ISSN 0007-0912
    DOI 10.1016/j.bja.2022.09.012
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