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  1. Article ; Online: 'Assisting their orphaned children when in need'.

    Holmøy, Trygve

    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke

    2024  Volume 144, Issue 4

    Title translation «At komme deres værdige og trængende Efterladte til Hjælp».
    MeSH term(s) Child ; Humans ; Child, Orphaned
    Language Norwegian
    Publishing date 2024-03-18
    Publishing country Norway
    Document type Journal Article
    ZDB-ID 603504-8
    ISSN 0807-7096 ; 0029-2001
    ISSN (online) 0807-7096
    ISSN 0029-2001
    DOI 10.4045/tidsskr.24.0066
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Norwegian health service should offer stem cell therapy for multiple sclerosis.

    Nygaard, Gro Owren / Holmøy, Trygve

    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke

    2024  Volume 144, Issue 2

    Title translation Norsk helsevesen bør tilby stamcellebehandling mot multippel sklerose.
    MeSH term(s) Humans ; Multiple Sclerosis/therapy ; Norway ; Health Services ; Cell- and Tissue-Based Therapy
    Language Norwegian
    Publishing date 2024-02-07
    Publishing country Norway
    Document type Journal Article
    ZDB-ID 603504-8
    ISSN 0807-7096 ; 0029-2001
    ISSN (online) 0807-7096
    ISSN 0029-2001
    DOI 10.4045/tidsskr.23.0770
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: A Novel

    Høyer, Helle / Nakken, Ola / Holmøy, Trygve

    Case reports in genetics

    2023  Volume 2023, Page(s) 4553365

    Abstract: Genetic variants ... ...

    Abstract Genetic variants in
    Language English
    Publishing date 2023-12-31
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2664417-4
    ISSN 2090-6552 ; 2090-6544
    ISSN (online) 2090-6552
    ISSN 2090-6544
    DOI 10.1155/2023/4553365
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The first Norwegian doctorate in multiple sclerosis.

    Holmøy, Trygve / Jørstad, Øystein Kalsnes

    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke

    2021  Volume 141, Issue 5

    Title translation Den første norske doktorgraden om multippel sklerose.
    MeSH term(s) Humans ; Multiple Sclerosis/diagnosis ; Multiple Sclerosis/drug therapy ; Norway/epidemiology
    Language Norwegian
    Publishing date 2021-03-22
    Publishing country Norway
    Document type Journal Article
    ZDB-ID 603504-8
    ISSN 0807-7096 ; 0029-2001
    ISSN (online) 0807-7096
    ISSN 0029-2001
    DOI 10.4045/tidsskr.20.0993
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Re: Kronisk utmattelsessyndrom/myalgisk encefalopati--sykdomsmekanismer, diagnostikk og behandling.

    Holmøy, Trygve

    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke

    2016  Volume 136, Issue 3, Page(s) 204–205

    MeSH term(s) Fatigue Syndrome, Chronic ; Humans
    Language Norwegian
    Publishing date 2016-02-09
    Publishing country Norway
    Document type Comment ; Letter
    ZDB-ID 603504-8
    ISSN 0807-7096 ; 0029-2001
    ISSN (online) 0807-7096
    ISSN 0029-2001
    DOI 10.4045/tidsskr.16.0051
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: BCG vaccination and multiple sclerosis risk: A Norwegian cohort study.

    Nakken, Ola / Aarseth, Jan Harald / Wergeland, Stig / Stigum, Hein / Meyer, Haakon E / Holmøy, Trygve

    Multiple sclerosis (Houndmills, Basingstoke, England)

    2024  , Page(s) 13524585241230440

    Abstract: Introduction: Bacillus Calmette-Guérin (BCG) vaccination induces long-lasting effects on the adaptive and innate immune systems and prevents development of experimental autoimmune encephalomyelitis and possibly also inflammatory disease activity in ... ...

    Abstract Introduction: Bacillus Calmette-Guérin (BCG) vaccination induces long-lasting effects on the adaptive and innate immune systems and prevents development of experimental autoimmune encephalomyelitis and possibly also inflammatory disease activity in multiple sclerosis (MS).
    Objective: The objective is to examine if BCG given in early adulthood decreases MS risk.
    Methods: From 791,369 (52% females) Norwegians participating in a national tuberculosis screening program from 1963 to 1975, we collected information on BCG vaccination and tuberculosis disease status. Later, MS disease was ascertained through both the Norwegian MS Registry and Biobank and the Norwegian Death Registry. We used logistic regression models to assess the relationship between BCG vaccination and MS risk.
    Results: In those BCG vaccinated, mean age at vaccination was 15.6 (standard deviation (SD) = 5.5) years. A total of 2862 (65% females) MS cases were retrieved. Overall, we found no association between MS risk and BCG vaccination. Compared to non-BCG-vaccinated individuals with no signs of tuberculosis infection, odds ratio (OR) for MS was 1.00 (95% confidence interval (CI) = 0.80-1.25) in the BCG-vaccinated group. In those not BCG vaccinated because of latent tuberculosis infection, the corresponding OR was 0.86 (95% CI = 0.66-1.13).
    Conclusion: We found no evidence of BCG vaccination or latent tuberculosis infection in young adulthood being linked to MS risk.
    Language English
    Publishing date 2024-02-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 1290669-4
    ISSN 1477-0970 ; 1352-4585
    ISSN (online) 1477-0970
    ISSN 1352-4585
    DOI 10.1177/13524585241230440
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Continuous improvement in MS treatment.

    Holmøy, Trygve / Bø, Lars

    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke

    2020  Volume 140, Issue 5

    Title translation MS-behandlingen blir stadig bedre.
    Language Norwegian
    Publishing date 2020-03-30
    Publishing country Norway
    Document type Journal Article
    ZDB-ID 603504-8
    ISSN 0807-7096 ; 0029-2001
    ISSN (online) 0807-7096
    ISSN 0029-2001
    DOI 10.4045/tidsskr.20.0198
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Progressive encephalomyelitis with rigidity and myoclonus (PERM) associated with anti-glycine receptor antibodies and urothelial carcinoma: a case report.

    Ali, Amanuel Hassen / Benterud, Anna / Holmøy, Trygve / Myro, Aija Zuleron

    Journal of medical case reports

    2023  Volume 17, Issue 1, Page(s) 330

    Abstract: Background: Progressive encephalomyelitis with rigidity and myoclonus (PERM) is a rare neurological condition with paraneoplastic etiology in about 20% of cases, usually presenting before or shortly after the oncological diagnosis is established. PERM ... ...

    Abstract Background: Progressive encephalomyelitis with rigidity and myoclonus (PERM) is a rare neurological condition with paraneoplastic etiology in about 20% of cases, usually presenting before or shortly after the oncological diagnosis is established. PERM associated with anti-glycine receptor antibodies is not previously reported in a patient with bladder cancer.
    Case presentation: A 72-years-old Caucasian male was admitted with acute onset of dysarthria, dysphagia and trismus three years after initial surgical treatment for bladder cancer. The condition was initially diagnosed as tetanus and treated accordingly, but the diagnosis was reconsidered because of progression despite adequate treatment. Diagnostic workup on readmission revealed lung and paraaortal metastases from bladder cancer and anti-glycine receptor (anti-GlyR) antibodies both in the cerebrospinal fluid and in serum, which supplemented with the clinical presentation led to the diagnosis of PERM, presumably related to bladder cancer. The patient showed improvement and stabilization after treatment with intravenous immunoglobulin and chemotherapy against metastatic bladder cancer.
    Conclusion: To the best of our knowledge, this is the first reported case of anti-GlyR antibody positive PERM related to urothelial carcinoma. The symptoms mimicked tetanus, and responded to chemotherapy and immunotherapy.
    MeSH term(s) Humans ; Male ; Aged ; Myoclonus/complications ; Carcinoma, Transitional Cell ; Tetanus/complications ; Urinary Bladder Neoplasms/complications ; Urinary Bladder Neoplasms/therapy ; Encephalomyelitis/complications ; Encephalomyelitis/diagnosis
    Language English
    Publishing date 2023-08-03
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2269805-X
    ISSN 1752-1947 ; 1752-1947
    ISSN (online) 1752-1947
    ISSN 1752-1947
    DOI 10.1186/s13256-023-04059-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: A. H. Ali og medarbeidere svarer.

    Ali, Amanuel Hassen / Høyer, Helle / Rugland, Eyvind / Holmøy, Trygve

    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke

    2022  Volume 142, Issue 13

    Title translation A.H. Ali et al. respond
    Language Norwegian
    Publishing date 2022-09-26
    Publishing country Norway
    Document type Journal Article
    ZDB-ID 603504-8
    ISSN 0807-7096 ; 0029-2001
    ISSN (online) 0807-7096
    ISSN 0029-2001
    DOI 10.4045/tidsskr.22.0560
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: A woman in her fifties with progressive walking difficulties.

    Ali, Amanuel Hassen / Høyer, Helle / Rugland, Eyvind / Holmøy, Trygve

    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke

    2022  Volume 142, Issue 11

    Abstract: A woman in her fifties developed gradually increasing unsteadiness and weakness in her legs. Clinical investigation raised suspicion of an immunological disorder. However, immunomodulatory therapy had no effect. Further investigation two and a half years ...

    Title translation En kvinne i 50-årene med økende gangvansker.
    Abstract A woman in her fifties developed gradually increasing unsteadiness and weakness in her legs. Clinical investigation raised suspicion of an immunological disorder. However, immunomodulatory therapy had no effect. Further investigation two and a half years after the initial contact with a doctor revealed another diagnosis, which led to a change in treatment strategy.
    MeSH term(s) Female ; Humans ; Leg ; Walking
    Language Norwegian
    Publishing date 2022-07-28
    Publishing country Norway
    Document type Journal Article
    ZDB-ID 603504-8
    ISSN 0807-7096 ; 0029-2001
    ISSN (online) 0807-7096
    ISSN 0029-2001
    DOI 10.4045/tidsskr.21.0522
    Database MEDical Literature Analysis and Retrieval System OnLINE

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