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Book ; Online ; E-Book: Handbook of microbiome and gut-brain-axis in Alzheimer's disease

Pasinetti, Giulio Maria

(Advances in Alzheimer's disease ; volume 9)

2022

Author's details	edited by Giulio Maria Pasinetti
Series title	Advances in Alzheimer's disease ; volume 9
Keywords	Gastrointestinal system/Microbiology ; Alzheimer's disease
Subject code	612.3/601579
Language	English
Size	1 online resource (732 pages)
Publisher	IOS Press
Publishing place	Amsterdam, Netherlands
Document type	Book ; Online ; E-Book
Note	Includes indexes.
Remark	Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
ISBN	9781643682891 ; 9781643682884 ; 164368289X ; 1643682881
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article: Right Hemicolectomy with Complete Mesocolic Excision Using the Versius Surgical System: A Step-by-Step Guide.

Baldari, Ludovica / Boni, Luigi / Cassinotti, Elisa / Crippa, Jacopo / Mari, Giulio

Chirurgia (Bucharest, Romania : 1990)

2023 Volume 118, Issue 1, Page(s) 54–62

Abstract: The application of new robotic platforms in colorectal surgery has increased greatly in the last 10 years. New systems have been released and entered the surgical panorama, broadening the technological offer. Robotic surgery applied to colorectal ... ...

Abstract	The application of new robotic platforms in colorectal surgery has increased greatly in the last 10 years. New systems have been released and entered the surgical panorama, broadening the technological offer. Robotic surgery applied to colorectal oncological surgery has been widely described. Hybrid robotic surgery in right sided colonic cancer has been previously reported. According to the site and local extension of a right-sided colon cancer, a different lymphadenectomy could be required. For more distant and locally advanced tumors a complete mesocolic excision (CME) is indicated. CME for right colon cancer is a complex operation compared to standard right hemicolectomy. Therefore a hybrid robotic system may be effectively applied to CME during a minimally-invasive right hemicolectomy to improve the dissection accuracy. Here we report a step-by-step hybrid laparoscopic/robotic right hemicolectomy with CME performed with the Versius Surgical System, a tele-operated surgical robotic system intended for the use of robotic assisted surgery.
MeSH term(s)	Humans ; Robotic Surgical Procedures ; Treatment Outcome ; Laparoscopy ; Lymph Node Excision ; Colonic Neoplasms/surgery ; Colonic Neoplasms/pathology ; Colectomy
Language	English
Publishing date	2023-03-13
Publishing country	Romania
Document type	Journal Article
ZDB-ID	419244-8
ISSN	1842-368X ; 1221-9118 ; 0009-4730 ; 0377-5003
ISSN (online)	1842-368X
ISSN	1221-9118 ; 0009-4730 ; 0377-5003
DOI	10.21614/chirurgia.2828
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Article ; Online: Charting connections: A systematic review of colorectal surgery research networks.

Crippa, Jacopo / Magistro, Carmelo / Montroni, Isacco / Borroni, Giacomo / Ziccarelli, Antonio / Spinelli, Antonino / Mari, Giulio Maria

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

2024 Volume 50, Issue 6, Page(s) 108322

Abstract: Research in surgery faces intrinsic difficulties such as the lack of reproducibility of surgical operations, self-referring surgeons, decentralized data. Establishing a community of qualified researchers across surgeons is crucial. Clinical networks have ...

Abstract	Research in surgery faces intrinsic difficulties such as the lack of reproducibility of surgical operations, self-referring surgeons, decentralized data. Establishing a community of qualified researchers across surgeons is crucial. Clinical networks have been proposed as solutions to many challenges in surgical research, yet their implementation remains uncommon, especially for surgical trialists. The extent of literature produced by networks remains unclear, but fostering such collaborations could enhance the overall quality of surgical research. We conducted review focusing on research networks in colorectal surgery to assess their workload and impact in the literature and identify factors contributing to their durability. Following PRISMA guidelines, we searched for articles published through research networks. Networks were categorized by subspecialty, and specific items were retrieved for further classification. A survey was administered to twenty experts in colorectal surgery or research networking. A total of 2490 manuscripts were screened, and 397 networks identified. Of these, 96 were colorectal networks contributing to 492 publications, with 28 networks having five or more publications. Seventeen networks were affiliated with International or National societies, and only 5 conducted both prospective trials and RCTs. Twenty networks reported national or population-based data, and 26 networks lasted for more than 5 years. Sixteen experts participated in the survey, with an 80 % compliance rate, and 12 of them have been involved in creating a surgical network. The large majority of experts advocate the establishment of guidelines for networks creation in the surgical community.
Language	English
Publishing date	2024-04-17
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	632519-1
ISSN	1532-2157 ; 0748-7983
ISSN (online)	1532-2157
ISSN	0748-7983
DOI	10.1016/j.ejso.2024.108322
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Article ; Online: ERAS Protocol Applied to Oncological Colorectal Mini-invasive Surgery Reduces the Surgical Stress Response and Improves Long-term Cancer-specific Survival.

Crippa, Jacopo / Calini, Giacomo / Santambrogio, Gaia / Sassun, Richard / Siracusa, Claudia / Maggioni, Dario / Mari, Giulio

Surgical laparoscopy, endoscopy & percutaneous techniques

2023 Volume 33, Issue 3, Page(s) 297–301

Abstract: ... In 2016, Mari et al published a randomized trial on ERAS protocol and the impact on the SSR; they found ...

Abstract	Background: Enhanced recovery after surgery (ERAS) protocols are known to reduce postoperative complications and improve short-term outcomes by minimizing the surgical stress response (SSR). Retrospective reviews of large cohorts suggest that they may also have an impact on long-term oncological outcomes. In 2016, Mari et al published a randomized trial on ERAS protocol and the impact on the SSR; they found that IL-6 was less expressed in patients who undergo laparoscopic colorectal surgery within an ERAS protocol compared with controls. The aim of the present study is to report the long-term oncological outcomes of patients enrolled 5 years after the conclusion of the study. Methods: Patients enrolled had received the indication for major colorectal surgery, aged between 18 and 80 years, with American Society of Anesthesiologists (ASA) grades I to III, autonomous for mobilization and walking, eligible for laparoscopic technique. In total, 140 patients were enrolled and randomized into 2 groups of 70 patients each. Among these patients, 52 in the ERAS group (EG) and 53 in the Standard group (SG) had colorectal cancer. For them, a 5-year oncological follow-up according to the NCCN 16 guidelines was planned. IL-6, C-reactive protein, prolactine, white blood cell count, albumin, and prealbumin were compared between oncological patients in the EG and in the SG. Results: EG showed lower IL-6 on postoperative day 1 (21.2±9.1 vs. 40.3 ±11.3; P <0.05) and on day 5 (14.9±6.2 vs. 38.7±8.9; P <0.05), lower C-reactive protein on day 1 (48.3±15.7 vs. 89.4±20.3; P <0.05) and on day 5 (38.3±11.4 vs. 74.3±19.7; P <0.05), and lower pre-albumine on day 5 (18.9±7.2 vs. 12.3±6.9; P <0.05) compared with SG. Median oncological follow-up was 57 months [46.5 to 60]. There was no statistically significant difference in overall survival (log rank=0.195) and disease-free survival (Log rank=0.089) between groups. Cancer-specific survival was significantly better (log rank=0.038) in the EG compared with patients in the SG. Conclusions: ERAS protocol applied to colorectal laparoscopic surgery for cancer is able to minimize the SSR. As a possible result, cancer-specific survival seems to be improved in patients within enhanced protocols. However, even though there may be an association between an excess of SSR and worse oncological outcomes, the favorable effect of ERAS protocols toward better overall and disease-free survival is yet to be demonstrated.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Humans ; Middle Aged ; Young Adult ; C-Reactive Protein/metabolism ; Colorectal Neoplasms/surgery ; Colorectal Surgery ; Enhanced Recovery After Surgery ; Interleukin-6 ; Laparoscopy/methods ; Length of Stay ; Postoperative Complications/surgery ; Recovery of Function ; Retrospective Studies
Chemical Substances	C-Reactive Protein (9007-41-4) ; Interleukin-6
Language	English
Publishing date	2023-06-01
Publishing country	United States
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	1475108-2
ISSN	1534-4908 ; 1530-4515 ; 1051-7200
ISSN (online)	1534-4908
ISSN	1530-4515 ; 1051-7200
DOI	10.1097/SLE.0000000000001181
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Article: Transperitoneal laparoscopic retrievement of a migrated prosthetic head after total hip arthroplasty: a case report.

Ciciriello, Simone / Gerosa, Martino / Ghezzi, Riccardo / Sogni, Angelo / Incalza, Ferdinando / Guttadauro, Angelo / Maggioni, Dario / Mari, Giulio

Frontiers in surgery

2023 Volume 10, Page(s) 1227026

Abstract: The migration of a prosthetic head during total hip arthroplasty (THA) is a rare complication. Few cases are described in the literature, offering different solutions and surgical approaches for prosthetic head retrievement. Here, we present a case of ... ...

Abstract	The migration of a prosthetic head during total hip arthroplasty (THA) is a rare complication. Few cases are described in the literature, offering different solutions and surgical approaches for prosthetic head retrievement. Here, we present a case of successful laparoscopic transperitoneal retrieval of a prosthetic head migrated above the right iliac vein after THA with a posterolateral approach.
Language	English
Publishing date	2023-07-27
Publishing country	Switzerland
Document type	Case Reports
ZDB-ID	2773823-1
ISSN	2296-875X
ISSN	2296-875X
DOI	10.3389/fsurg.2023.1227026
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Article ; Online: 'Reply to: Exploring the potential appropriateness of high ligation for a specific demographic'.

Crippa, Jacopo / Santambrogio, Gaia / Spinelli, Antonino / Montroni, Isacco / Cirocchi, Roberto / Fingerhut, Abe / Mari, Giulio M

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

2023 Volume 49, Issue 9, Page(s) 106998

MeSH term(s)	Humans ; Ligation ; Demography
Language	English
Publishing date	2023-07-29
Publishing country	England
Document type	Letter ; Comment
ZDB-ID	632519-1
ISSN	1532-2157 ; 0748-7983
ISSN (online)	1532-2157
ISSN	0748-7983
DOI	10.1016/j.ejso.2023.106998
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Article: Symptomatic Uncomplicated Diverticular Disease (SUDD): Practical Guidance and Challenges for Clinical Management.

Calini, Giacomo / Abd El Aziz, Mohamed A / Paolini, Lucia / Abdalla, Solafah / Rottoli, Matteo / Mari, Giulio / Larson, David W

Clinical and experimental gastroenterology

2023 Volume 16, Page(s) 29–43

Abstract: Symptomatic Uncomplicated Diverticular Disease (SUDD) is a syndrome within the diverticular disease spectrum, characterized by local abdominal pain with bowel movement changes but without systemic inflammation. This narrative review reports current ... ...

Abstract	Symptomatic Uncomplicated Diverticular Disease (SUDD) is a syndrome within the diverticular disease spectrum, characterized by local abdominal pain with bowel movement changes but without systemic inflammation. This narrative review reports current knowledge, delivers practical guidance, and reveals challenges for the clinical management of SUDD. A broad and common consensus on the definition of SUDD is still needed. However, it is mainly considered a chronic condition that impairs quality of life (QoL) and is characterized by persistent left lower quadrant abdominal pain with bowel movement changes (eg, diarrhea) and low-grade inflammation (eg, elevated calprotectin) but without systemic inflammation. Age, genetic predisposition, obesity, physical inactivity, low-fiber diet, and smoking are considered risk factors. The pathogenesis of SUDD is not entirely clarified. It seems to result from an interaction between fecal microbiota alterations, neuro-immune enteric interactions, and muscular system dysfunction associated with a low-grade and local inflammatory state. At diagnosis, it is essential to assess baseline clinical and Quality of Life (QoL) scores to evaluate treatment efficacy and, ideally, to enroll patients in cohort studies, clinical trials, or registries. SUDD treatments aim to improve symptoms and QoL, prevent recurrence, and avoid disease progression and complications. An overall healthy lifestyle - physical activity and a high-fiber diet, with a focus on whole grains, fruits, and vegetables - is encouraged. Probiotics could effectively reduce symptoms in patients with SUDD, but their utility is missing adequate evidence. Using Rifaximin plus fiber and Mesalazine offers potential in controlling symptoms in patients with SUDD and might prevent acute diverticulitis. Surgery could be considered in patients with medical treatment failure and persistently impaired QoL. Still, studies with well-defined diagnostic criteria for SUDD that evaluate the safety, QoL, effectiveness, and cost-effectiveness of these interventions using standard scores and comparable outcomes are needed.
Language	English
Publishing date	2023-03-28
Publishing country	New Zealand
Document type	Journal Article ; Review
ZDB-ID	2520690-4
ISSN	1178-7023
ISSN	1178-7023
DOI	10.2147/CEG.S340929
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Article ; Online: Surgery in phase 3 of the COVID-19 pandemic in Northern Italy spoke hospitals. Comments to "reply to letter to the editor: Surgery in the COVID-19 phase 2 Italian scenario: Lessons learned in Northern Italy spoke hospitals".

Costanzi, Andrea / Confalonieri, Marco / Mari, Giulio / Maggioni, Dario / Fingerhut, Abe

The journal of trauma and acute care surgery

2020 Volume 90, Issue 2, Page(s) e60

MeSH term(s)	COVID-19 ; Hospitals ; Humans ; Italy/epidemiology ; Pandemics ; SARS-CoV-2
Keywords	covid19
Language	English
Publishing date	2020-11-13
Publishing country	United States
Document type	Journal Article ; Comment
ZDB-ID	2651070-4
ISSN	2163-0763 ; 2163-0755
ISSN (online)	2163-0763
ISSN	2163-0755
DOI	10.1097/TA.0000000000003023
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Article ; Online: In response to: Surgery in the COVID-19 phase 2 Italian scenario: Lessons learned in Northern Italy spoke hospitals.

Costanzi, Andrea / Mari, Giulio / Confalonieri, Marco / Maggioni, Dario / Fingerhut, Abe

The journal of trauma and acute care surgery

2020 Volume 89, Issue 4, Page(s) e119–e120

MeSH term(s)	Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Disease Outbreaks ; Italy ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
Keywords	covid19
Language	English
Publishing date	2020-07-01
Publishing country	United States
Document type	Journal Article ; Comment
ZDB-ID	2651070-4
ISSN	2163-0763 ; 2163-0755
ISSN (online)	2163-0763
ISSN	2163-0755
DOI	10.1097/TA.0000000000002838
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Article ; Online: An underestimated "false negative COVID cholecystitis" in Northern Italy and the contagion of a surgical ward: it can happen everywhere.

Giulio, Mari / Achilli, Pietro / Dario, Maggioni

Updates in surgery

2020 Volume 72, Issue 2, Page(s) 315–316

MeSH term(s)	Acute Disease ; COVID-19 ; COVID-19 Testing ; Cholecystectomy, Laparoscopic ; Cholecystitis/complications ; Cholecystitis/drug therapy ; Cholecystitis/surgery ; Clinical Laboratory Techniques ; Coronavirus Infections/diagnosis ; Coronavirus Infections/etiology ; Coronavirus Infections/prevention & control ; Coronavirus Infections/transmission ; False Negative Reactions ; Female ; Humans ; Infectious Disease Transmission, Patient-to-Professional/prevention & control ; Italy ; Middle Aged ; Pandemics/prevention & control ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/etiology ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/transmission
Keywords	covid19
Language	English
Publishing date	2020-05-13
Publishing country	Italy
Document type	Case Reports ; Letter
ZDB-ID	2572692-4
ISSN	2038-3312 ; 2038-131X
ISSN (online)	2038-3312
ISSN	2038-131X
DOI	10.1007/s13304-020-00781-y
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