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  1. Book ; Conference proceedings: 11th International Workshop on Virus Evolution and Molecular Epidemiology

    Vandamme, Anne-Mieke

    Petrópolis, Brazil, 5 - 9 September 2005

    (Infection, genetics and evolution ; 7,3 = Special issue)

    2007  

    Event/congress International Workshop on Virus Evolution and Molecular Epidemiology (11, 2005, Petrópolis)
    Author's details guest ed.: A.-M. Vandamme
    Series title Infection, genetics and evolution ; 7,3 = Special issue
    Collection
    Language English
    Size S. 353 - 409 : graph. Darst.
    Publisher Elsevier
    Publishing place Amsterdam u.a.
    Publishing country Netherlands
    Document type Book ; Conference proceedings
    Note Enth. auch: Abstracts
    HBZ-ID HT015119596
    Database Catalogue ZB MED Medicine, Health

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  2. Book ; Conference proceedings: 9th International Workshop on Virus Evolution and Molecular Epidemiology

    Vandamme, Anne-Mieke

    Stanford, USA, 13 - 23 August 2003

    (Infection, genetics and evolution ; 5,3 = Special issue)

    2005  

    Event/congress International Workshop on Virus Evolution and Molecular Epidemiology (9, 2003, StanfordCalif.)
    Author's details guest ed.: A.-M. Vandamme
    Series title Infection, genetics and evolution ; 5,3 = Special issue
    Collection
    Language English
    Size S. 197 - 322 : Ill., graph. Darst.
    Publisher Elsevier
    Publishing place Amsterdam u.a.
    Publishing country Netherlands
    Document type Book ; Conference proceedings
    Note Enth. auch: Abstracts
    HBZ-ID HT014340937
    Database Catalogue ZB MED Medicine, Health

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  3. Book ; Conference proceedings: Sixth European Workshop on Virus Evolution and Molecular Epidemiology

    Vandamme, Anne-Mieke

    Leuven, Belgium, 4 - 9 September, 2000

    (Virus research ; 85,1 : Special issue)

    2002  

    Institution European Workshop on Virus Evolution and Molecular Epidemiology
    Author's details guest ed.: A.-M. Vandamme
    Series title Virus research ; 85,1 : Special issue
    Collection
    Language English
    Size VIII S., S. 1 - 122 : Ill., graph. Darst.
    Publisher Elsevier
    Publishing place Amsterdam u.a.
    Publishing country Netherlands
    Document type Book ; Conference proceedings
    HBZ-ID HT013344042
    Database Catalogue ZB MED Medicine, Health

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  4. Article ; Online: Belgium - concerns about coronavirus contact-tracing apps.

    Vandamme, Anne-Mieke / Nguyen, ToTran

    Nature

    2020  Volume 581, Issue 7809, Page(s) 384

    MeSH term(s) Belgium ; Betacoronavirus ; COVID-19 ; Computer Security ; Contact Tracing ; Coronavirus ; Coronavirus Infections/epidemiology ; Humans ; Mobile Applications ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-07-22
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/d41586-020-01552-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The Impact of Genital Ulcers on HIV Transmission Has Been Underestimated-A Critical Review.

    Sousa, João Dinis / Müller, Viktor / Vandamme, Anne-Mieke

    Viruses

    2022  Volume 14, Issue 3

    Abstract: In the early 1990s, several observational studies determined that genital ulcer disease (GUD), in either the index or the exposed person, facilitates HIV transmission. Several meta-analyses have since presented associated risk ratios (RR) over the ... ...

    Abstract In the early 1990s, several observational studies determined that genital ulcer disease (GUD), in either the index or the exposed person, facilitates HIV transmission. Several meta-analyses have since presented associated risk ratios (RR) over the baseline per-act transmission probability (PATP) usually in the range of 2-5. Here we review all relevant observational studies and meta-analyses, and show that the estimation of RRs was, in most cases, biased by assuming the presence of GUD at any time during long follow-up periods, while active genital ulcers were present in a small proportion of the time. Only two studies measured the GUD co-factor effect in PATPs focusing on acts in which ulcers were present, and both found much higher RRs (in the range 11-112). We demonstrate that these high RRs can be reconciled with the studies on which currently accepted low RRs were based, if the calculations are restricted to the actual GUD episodes. Our results indicate that the effect of genital ulcers on the PATP of HIV might be much greater than currently accepted. We conclude that the medical community should work on the assumption that HIV risk is very high during active genital ulcers.
    MeSH term(s) Genital Diseases, Female ; Genitalia ; HIV Infections ; Humans ; Ulcer
    Language English
    Publishing date 2022-03-05
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v14030538
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Qualitative systems mapping for complex public health problems

    Anneleen Kiekens / Bernadette Dierckx de Casterlé / Anne-Mieke Vandamme

    PLoS ONE, Vol 17, Iss 2, p e

    A practical guide.

    2022  Volume 0264463

    Abstract: Systems mapping methods are increasingly used to study complex public health issues. Visualizing the causal relationships within a complex adaptive system allows for more than developing a holistic and multi-perspective overview of the situation. It is ... ...

    Abstract Systems mapping methods are increasingly used to study complex public health issues. Visualizing the causal relationships within a complex adaptive system allows for more than developing a holistic and multi-perspective overview of the situation. It is also a way of understanding the emergent, self-organizing dynamics of a system and how they can be influenced. This article describes a concrete approach for developing and analysing a systems map of a complex public health issue drawing on well-accepted methods from the field of social science while incorporating the principles of systems thinking and transdisciplinarity. Using our case study on HIV drug resistance in sub-Saharan Africa as an example, this article provides a practical guideline on how to map a public health problem as a complex adaptive system in order to uncover the drivers, feedback-loops and other dynamics behind the problem. Qualitative systems mapping can help researchers and policy makers to gain deeper insights in the root causes of the problem and identify complexity-informed intervention points.
    Keywords Medicine ; R ; Science ; Q
    Subject code 360
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Qualitative systems mapping for complex public health problems: A practical guide.

    Kiekens, Anneleen / Dierckx de Casterlé, Bernadette / Vandamme, Anne-Mieke

    PloS one

    2022  Volume 17, Issue 2, Page(s) e0264463

    Abstract: Systems mapping methods are increasingly used to study complex public health issues. Visualizing the causal relationships within a complex adaptive system allows for more than developing a holistic and multi-perspective overview of the situation. It is ... ...

    Abstract Systems mapping methods are increasingly used to study complex public health issues. Visualizing the causal relationships within a complex adaptive system allows for more than developing a holistic and multi-perspective overview of the situation. It is also a way of understanding the emergent, self-organizing dynamics of a system and how they can be influenced. This article describes a concrete approach for developing and analysing a systems map of a complex public health issue drawing on well-accepted methods from the field of social science while incorporating the principles of systems thinking and transdisciplinarity. Using our case study on HIV drug resistance in sub-Saharan Africa as an example, this article provides a practical guideline on how to map a public health problem as a complex adaptive system in order to uncover the drivers, feedback-loops and other dynamics behind the problem. Qualitative systems mapping can help researchers and policy makers to gain deeper insights in the root causes of the problem and identify complexity-informed intervention points.
    MeSH term(s) Africa ; Anti-Retroviral Agents/therapeutic use ; Drug Resistance, Viral ; HIV Infections/drug therapy ; HIV Infections/pathology ; Humans ; Policy Making ; Public Health ; Systems Analysis
    Chemical Substances Anti-Retroviral Agents
    Language English
    Publishing date 2022-02-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0264463
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: The Impact of Genital Ulcers on HIV Transmission Has Been Underestimated—A Critical Review

    Sousa, João Dinis / Müller, Viktor / Vandamme, Anne-Mieke

    Viruses. 2022 Mar. 05, v. 14, no. 3

    2022  

    Abstract: In the early 1990s, several observational studies determined that genital ulcer disease (GUD), in either the index or the exposed person, facilitates HIV transmission. Several meta-analyses have since presented associated risk ratios (RR) over the ... ...

    Abstract In the early 1990s, several observational studies determined that genital ulcer disease (GUD), in either the index or the exposed person, facilitates HIV transmission. Several meta-analyses have since presented associated risk ratios (RR) over the baseline per-act transmission probability (PATP) usually in the range of 2–5. Here we review all relevant observational studies and meta-analyses, and show that the estimation of RRs was, in most cases, biased by assuming the presence of GUD at any time during long follow-up periods, while active genital ulcers were present in a small proportion of the time. Only two studies measured the GUD co-factor effect in PATPs focusing on acts in which ulcers were present, and both found much higher RRs (in the range 11–112). We demonstrate that these high RRs can be reconciled with the studies on which currently accepted low RRs were based, if the calculations are restricted to the actual GUD episodes. Our results indicate that the effect of genital ulcers on the PATP of HIV might be much greater than currently accepted. We conclude that the medical community should work on the assumption that HIV risk is very high during active genital ulcers.
    Keywords bias ; exhibitions ; meta-analysis ; observational studies ; people ; relative risk ; viruses
    Language English
    Dates of publication 2022-0305
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2516098-9
    ISSN 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v14030538
    Database NAL-Catalogue (AGRICOLA)

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  9. Article: Transferable data exclusivity vouchers are not the solution to the antimicrobial drug development crisis: a commentary on the proposed EU pharma regulation.

    Berner-Rodoreda, Astrid / Cobelens, Frank / Vandamme, Anne-Mieke / Froeschl, Günter / Skordis, Jolene / Renganathan, Elil / t'Hoen, Ellen / Raviglione, Mario / Jahn, Albrecht / Bärnighausen, Till

    BMJ global health

    2024  Volume 9, Issue 2

    MeSH term(s) Humans ; Anti-Infective Agents/therapeutic use ; Health Policy ; Drug Development
    Chemical Substances Anti-Infective Agents
    Language English
    Publishing date 2024-02-28
    Publishing country England
    Document type Journal Article
    ISSN 2059-7908
    ISSN 2059-7908
    DOI 10.1136/bmjgh-2023-014605
    Database MEDical Literature Analysis and Retrieval System OnLINE

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