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Article ; Online: Hypoxia Does Not Impair Resistance Exercise Performance or Amplify Post-Exercise Fatigue.

Jonson, Andrew M / Girard, Olivier / Walden, Thomas P / Marston, Kieran J / Scott, Brendan R

Research quarterly for exercise and sport

2023 Volume 95, Issue 1, Page(s) 235–242

Abstract: Purpose: ...

Abstract	Purpose:
MeSH term(s)	Male ; Humans ; Resistance Training ; Exercise ; Hypoxia ; Oxygen ; Fatigue
Chemical Substances	Oxygen (S88TT14065)
Language	English
Publishing date	2023-04-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	225654-x
ISSN	2168-3824 ; 0270-1367
ISSN (online)	2168-3824
ISSN	0270-1367
DOI	10.1080/02701367.2023.2193232
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Article ; Online: Blood flow restricted walking alters gait kinematics.

Walden, Thomas P / Fairchild, Timothy / Girard, Olivier / Peiffer, Jeremiah J / Jonson, Andrew M / Dempsey, Alasdair R

European journal of sport science

2023 Volume 23, Issue 8, Page(s) 1528–1537

Abstract: This study investigated the impact of blood flow restriction (BFR) during treadmill walking on gait kinematics. Twenty-one participants completed one familiarisation and four experimental sessions, including two walking speeds (moderate [5.0 ± 0.3km· ... ...

Abstract	This study investigated the impact of blood flow restriction (BFR) during treadmill walking on gait kinematics. Twenty-one participants completed one familiarisation and four experimental sessions, including two walking speeds (moderate [5.0 ± 0.3km·h
MeSH term(s)	Humans ; Biomechanical Phenomena ; Walking/physiology ; Gait ; Hemodynamics ; Regional Blood Flow/physiology ; Lactates ; Muscle, Skeletal/blood supply
Chemical Substances	Lactates
Language	English
Publishing date	2023-04-04
Publishing country	England
Document type	Journal Article
ISSN	1536-7290
ISSN (online)	1536-7290
DOI	10.1080/17461391.2023.2194274
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Article ; Online: Does the application of blood flow restriction during walking exercise influence the accuracy of indirect calorimetry?

Walden, Thomas P / Girard, Olivier / Scott, Brendan R / Jonson, Andrew M / Peiffer, Jeremiah J

Journal of science and medicine in sport

2022 Volume 25, Issue 8, Page(s) 673–677

Abstract: Objectives: Identify whether the application of blood flow restriction (BFR) during walking influences fraction of expired oxygen (F: Design: Randomised cross-over.: Methods: On separate visits, sixteen participants completed four experimental ... ...

Abstract	Objectives: Identify whether the application of blood flow restriction (BFR) during walking influences fraction of expired oxygen (F Design: Randomised cross-over. Methods: On separate visits, sixteen participants completed four experimental sessions (order randomised), each comprising 10 min of treadmill exercise; i.e., with or without BFR (60% arterial occlusion pressure) combined with two different intensity levels (100% or 120% comfortable walking speed). For data analysis, walking speeds within the same condition (with or without BFR) were pooled, and the speed variance was controlled within the statistical model. The F Results: Condition × time interactions were observed for F Conclusions: The increase of F
MeSH term(s)	Calorimetry, Indirect ; Carbon Dioxide/metabolism ; Exercise/physiology ; Humans ; Oxygen ; Oxygen Consumption/physiology ; Walking/physiology
Chemical Substances	Carbon Dioxide (142M471B3J) ; Oxygen (S88TT14065)
Language	English
Publishing date	2022-04-27
Publishing country	Australia
Document type	Journal Article
ZDB-ID	1437829-2
ISSN	1878-1861 ; 1440-2440
ISSN (online)	1878-1861
ISSN	1440-2440
DOI	10.1016/j.jsams.2022.04.006
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Low- to moderate-intensity blood flow restricted walking is not an acute equivalent for unrestricted jogging in young active adults.

Walden, Thomas P / Girard, Olivier / Scott, Brendan R / Jonson, Andrew M / Peiffer, Jeremiah J

European journal of sport science

2022 Volume 23, Issue 8, Page(s) 1560–1569

Abstract: This study investigated whether walking with blood flow restriction (BFR) increases acute cardio-respiratory demands to the point that it can be considered an alternative for jogging. Sixteen physically active adults completed five experimental sessions ( ...

Abstract	This study investigated whether walking with blood flow restriction (BFR) increases acute cardio-respiratory demands to the point that it can be considered an alternative for jogging. Sixteen physically active adults completed five experimental sessions (order randomised), comprising 10 min of treadmill exercise. Two sessions included unrestricted walking, two sessions required walking with BFR cuffs positioned on the lower limbs inflated to 60% of individualised arterial occlusion pressure, and one session was conducted at a jogging pace. Comfortable walking and jogging speeds were calculated during the familiarisation session. Walking speeds were individualised to either 100% (speed: 6.0 ± 0.3km·h-1[low-intensity]) or 120% (speed: 7.2 ± 0.3km·h-1[moderate-intensity]) of comfortable walking speed. The jogging session was unrestricted (speed: 9.1 ± 0.7km·h-1). Initial analysis compared walking conditions across heart rate, left cardiac work index, systolic blood pressure, relative oxygen consumption, minute ventilation, rating of perceived exertion and limb discomfort. Secondary analysis compared the walking session with the highest cardio-respiratory demands to jogging. Initial analysis identified that moderate-intensity with BFR induced the highest cardio-respiratory and perceptual responses compared with any other walking sessions (
MeSH term(s)	Adult ; Humans ; Jogging ; Regional Blood Flow/physiology ; Hemodynamics/physiology ; Walking/physiology ; Exercise/physiology
Language	English
Publishing date	2022-08-22
Publishing country	England
Document type	Journal Article
ISSN	1536-7290
ISSN (online)	1536-7290
DOI	10.1080/17461391.2022.2107436
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Article ; Online: The intensity of a resistance exercise session can be quantified by the work rate of exercise.

Scott, Brendan R / Marston, Kieran J / Teo, Shaun Y M / Forrest, Mitchell R L / Jonson, Andrew / Walden, Thomas P / Galna, Brook / Peiffer, Jeremiah J

PloS one

2023 Volume 18, Issue 10, Page(s) e0291857

Abstract: ... for 8x3 than 3x10 protocols (p<0.001), but not different within these configurations. Internal intensity ...

Abstract	Purpose: Athletes regularly perform resistance training, yet it is unknown how best to monitor its intensity. This study compared different resistance exercise intensity metrics to determine their sensitivity to manipulating work rate (via altering inter-set rest and load). Methods: Following baseline testing for 10- and 3-repetition maximum (RM; squat and bench press), fourteen trained participants completed four volume-matched protocols in a randomised order: 3x10 with 85% 10RM, 60 s rest (3x1060s); 3x10 with 85% 10RM, 180 s (3x10180s); 8x3 with 85% 3RM, 120 s (8x3120s); 8x3 with 85% 3RM, 300 s (8x3300s). Internal intensity was quantified via rate of oxygen consumption ([Formula: see text]), heart rate, blood lactate concentration, and rating of perceived exertion (RPE). External intensity was assessed via previously developed "Training-Intensity" (TI) and "Intensity-Index" (II) metrics, and from exercise work rate (expressed as kg∙min-1 and joules∙min-1). Results: Internal intensity and work-rate metrics were highest for 3x1060s, followed by 3x10180s, 8x3120s and 8x3300s (p≤0.027). TI and II were higher for 8x3 than 3x10 protocols (p<0.001), but not different within these configurations. Internal intensity measures were more strongly correlated with work rate (r = 0.37-0.96) than TI and II (r = -0.42-0.33) metrics. Conclusions: Work rate corroborated objective internal intensity metrics during resistance exercise, with the highest work rate session (3x1060s) also eliciting greater RPE scores than other protocols. In contrast, the TI and II did not agree with other intensity measures, likely because they do not consider rest periods. Practitioners can plan for the physiological and perceptual demands of resistance training by estimating work rate.
MeSH term(s)	Humans ; Physical Exertion/physiology ; Resistance Training/methods ; Exercise/physiology ; Lactic Acid ; Heart Rate
Chemical Substances	Lactic Acid (33X04XA5AT)
Language	English
Publishing date	2023-10-05
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0291857
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Article: An inguinal hernia 'hard to stomach'.

Liechty, Shawn / Eiref, Andrew D / Vengatesan, Keerthivasan / Barasch, Samuel P / Dong, Xiang D / Zimmerman, Patrick W / Nicoara, Michael / Patel, Krishan / Walden, Heath / Eiref, Simon D

Journal of surgical case reports

2023 Volume 2023, Issue 7, Page(s) rjad416

Abstract: Inguinal hernias containing the stomach are extremely rare, and have never been described in females. We are reporting the case of a 79 year old female who presented in septic shock with a left inguinal hernia containing the stomach, resulting in gastric ...

Abstract	Inguinal hernias containing the stomach are extremely rare, and have never been described in females. We are reporting the case of a 79 year old female who presented in septic shock with a left inguinal hernia containing the stomach, resulting in gastric perforation and loss of abdominal domain. She underwent emergency exploratory laparotomy with manual reduction of the hernia, wedge resection of the perforated gastric segment, abdominal washout, and closure of the abdominal fascia using biological mesh. She had a complicated but successful postoperative course, and was discharged to a rehabilitation center three weeks after hospital admission.
Language	English
Publishing date	2023-07-29
Publishing country	England
Document type	Case Reports
ZDB-ID	2580919-2
ISSN	2042-8812
ISSN	2042-8812
DOI	10.1093/jscr/rjad416
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Article ; Online: Outcomes of Activity-Related Lower Extremity Muscle Tears After Application of the British Athletics Muscle Injury Classification: A Systematic Review.

Hollabaugh, William L / Sin, Alexander / Walden, Rachel Lane / Weaver, Jennifer S / Porras, Lauren P / LeClere, Lance E / Karpinos, Ashley R / Coronado, Rogelio A / Gregory, Andrew J / Sullivan, Jaron P

Sports health

2023 , Page(s) 19417381231195529

Abstract: Context: Muscle injury classification and grading systems have been reported for >100 years; yet it offer limited evidence relating the clinical or radiological qualities of a muscle injury to the pathology or clinical outcome. The British Athletics ... ...

Abstract	Context: Muscle injury classification and grading systems have been reported for >100 years; yet it offer limited evidence relating the clinical or radiological qualities of a muscle injury to the pathology or clinical outcome. The British Athletics Muscle Injury Classification (BAMIC) incorporates recent predictive features of muscle injuries and provides a precise radiographic framework for clinical prediction and management. Objective: To investigate clinical outcomes, particularly time to return to play (RTP), reinjury rate (RIR), and prognostic value of specific magnetic resonance imaging (MRI) findings, of activity-related muscle injuries (tears) in athletes after application of the BAMIC. Data sources: A search of PubMed (NLM), EMBASE (Ovid), Web of Science (Clarivate), Cochrane Library (Wiley), and ClinicalTrials.gov from the inception date of each database through August 31, 2022, was conducted. Keywords included the BAMIC. Study selection: All English language studies evaluating clinical outcomes of RTP and RIR after activity-related muscle injuries and where BAMIC was applied were included. A total of 136 articles were identified, and 11 studies met inclusion criteria. Study design: Systematic review (PROSPERO: CRD42022353801). Level of evidence: Level 2. Data extraction: Two reviewers independently screened studies for eligibility and extracted data. Methodological quality of included study was assessed independently by 2 reviewers with the Newcastle-Ottawa Quality Scale (NOS); 11 good quality studies (4 prospective cohort studies, 7 retrospective cohort studies) with 468 athletes (57 female) and 574 muscle injuries were included. Results: All studies reported a statistically significant relationship between BAMIC grade, BAMIC injury site, and/or combined BAMIC grade and injury site with RTP. A statistically significant increased RIR was reported by BAMIC grade and BAMIC injury site in 2 of 4 and 3 of 4 studies, respectively. The prognostic value of individual MRI criteria was limited. Conclusion: Consistent evidence suggests that BAMIC offers prognostic and therapeutic guidance for clinical outcomes, particularly RTP and RIR, after activity-related muscle injuries in athletes that may be superior to previous muscle injury classification and grading systems.
Language	English
Publishing date	2023-09-08
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2508802-6
ISSN	1941-0921 ; 1941-7381
ISSN (online)	1941-0921
ISSN	1941-7381
DOI	10.1177/19417381231195529
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Article ; Online: The intensity of a resistance exercise session can be quantified by the work rate of exercise

Brendan R. Scott / Kieran J. Marston / Shaun Y. M. Teo / Mitchell R. L. Forrest / Andrew Jonson / Thomas P. Walden / Brook Galna / Jeremiah J. Peiffer

PLoS ONE, Vol 18, Iss

2023 Volume 10

Keywords	Medicine ; R ; Science ; Q
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Should point-of-care ultrasound become part of healthcare worker testing for COVID?

Smallwood, Nicholas / Walden, Andrew / Parulekar, Prashant / Dachsel, Martin

Clinical medicine (London, England)

2020 Volume 20, Issue 5, Page(s) 486–487

Abstract: The NHS in England has rapidly expanded staff testing for COVID-19 in order to allow healthcare workers who would otherwise be isolating with symptoms suspicious of COVID-19 to be cleared to work. However, the high false negative rate associated with ... ...

Abstract	The NHS in England has rapidly expanded staff testing for COVID-19 in order to allow healthcare workers who would otherwise be isolating with symptoms suspicious of COVID-19 to be cleared to work. However, the high false negative rate associated with current RT-PCR tests could put other staff, family members and patients at risk. We believe combining swab testing with real-time lung ultrasound (LUS) would improve the ability to rule-in COVID-19 infection in those requiring screening.
MeSH term(s)	COVID-19 ; COVID-19 Testing ; COVID-19 Vaccines ; Clinical Laboratory Techniques/methods ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Cross Infection/prevention & control ; Female ; Health Personnel/statistics & numerical data ; Humans ; Lung/diagnostic imaging ; Male ; Occupational Health ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; Point-of-Care Systems/organization & administration ; Severe Acute Respiratory Syndrome/diagnostic imaging ; Ultrasonography, Doppler/methods ; Ultrasonography, Doppler/statistics & numerical data ; United Kingdom
Chemical Substances	COVID-19 Vaccines ; Covid-19 aAPC vaccine
Keywords	covid19
Language	English
Publishing date	2020-07-17
Publishing country	England
Document type	Journal Article
ZDB-ID	2048646-7
ISSN	1473-4893 ; 1470-2118
ISSN (online)	1473-4893
ISSN	1470-2118
DOI	10.7861/clinmed.2020-0442
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Article ; Online: Phylogenomics of Parasitic and Nonparasitic Lice (Insecta: Psocodea): Combining Sequence Data and Exploring Compositional Bias Solutions in Next Generation Data Sets.

de Moya, Robert S / Yoshizawa, Kazunori / Walden, Kimberly K O / Sweet, Andrew D / Dietrich, Christopher H / Kevin P, Johnson

Systematic biology

2020 Volume 70, Issue 4, Page(s) 719–738

Abstract: The insect order Psocodea is a diverse lineage comprising both parasitic (Phthiraptera) and nonparasitic members (Psocoptera). The extreme age and ecological diversity of the group may be associated with major genomic changes, such as base compositional ... ...

Abstract	The insect order Psocodea is a diverse lineage comprising both parasitic (Phthiraptera) and nonparasitic members (Psocoptera). The extreme age and ecological diversity of the group may be associated with major genomic changes, such as base compositional biases expected to affect phylogenetic inference. Divergent morphology between parasitic and nonparasitic members has also obscured the origins of parasitism within the order. We conducted a phylogenomic analysis on the order Psocodea utilizing both transcriptome and genome sequencing to obtain a data set of 2370 orthologous genes. All phylogenomic analyses, including both concatenated and coalescent methods suggest a single origin of parasitism within the order Psocodea, resolving conflicting results from previous studies. This phylogeny allows us to propose a stable ordinal level classification scheme that retains significant taxonomic names present in historical scientific literature and reflects the evolution of the group as a whole. A dating analysis, with internal nodes calibrated by fossil evidence, suggests an origin of parasitism that predates the K-Pg boundary. Nucleotide compositional biases are detected in third and first codon positions and result in the anomalous placement of the Amphientometae as sister to Psocomorpha when all nucleotide sites are analyzed. Likelihood-mapping and quartet sampling methods demonstrate that base compositional biases can also have an effect on quartet-based methods.[Illumina; Phthiraptera; Psocoptera; quartet sampling; recoding methods.].
MeSH term(s)	Animals ; Anoplura ; Base Sequence ; Bias ; Insecta/genetics ; Phylogeny
Language	English
Publishing date	2020-10-17
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	1482572-7
ISSN	1076-836X ; 1063-5157
ISSN (online)	1076-836X
ISSN	1063-5157
DOI	10.1093/sysbio/syaa075
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