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  1. Article ; Online: Comprehensive review of resveratrol as a feed additive in dairy cows: exploring its potential diverse effects and implications.

    Rezaei Ahvanooei, M R / Norouzian, M A / Hedayati, M / Ghaffari, M H

    Veterinary research communications

    2023  Volume 47, Issue 3, Page(s) 1115–1124

    Abstract: Heat stress and growing demand for dairy products in tropical regions exert metabolic pressure on dairy cows, leading to metabolic diseases and economic losses. Resveratrol (RSV) is known for its numerous beneficial health effects and can be used as a ... ...

    Abstract Heat stress and growing demand for dairy products in tropical regions exert metabolic pressure on dairy cows, leading to metabolic diseases and economic losses. Resveratrol (RSV) is known for its numerous beneficial health effects and can be used as a barrier against metabolic abnormalities and prevent economic losses. Several studies have investigated the effects of RSV in humans and various animal species. In this review, we attempted to investigate the effects of RSV from different aspects so that we could have a practical proposal for its utilization in dairy cows. RSV was found to have potential antioxidant, anti-inflammatory, anti-obesity, and antimicrobial effects, leading to improved reproductive performance. It is interesting that the effect of RSV on the microbial population leads to a significant decrease in methane emissions. However, high doses of RSV have been associated with possible adverse effects, underscoring the dose dependence of its efficacy. In conclusion, RSV polyphenol at optimal doses is a promising agent for the prevention and treatment of metabolic abnormalities in dairy cows, based on our literature review and study results.
    MeSH term(s) Female ; Humans ; Cattle ; Animals ; Milk ; Lactation ; Resveratrol/metabolism ; Diet/veterinary ; Animal Feed/analysis
    Chemical Substances Resveratrol (Q369O8926L)
    Language English
    Publishing date 2023-07-08
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 406735-6
    ISSN 1573-7446 ; 0165-7380
    ISSN (online) 1573-7446
    ISSN 0165-7380
    DOI 10.1007/s11259-023-10157-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Effects of monensin supplementation on lactation performance of dairy cows: a systematic review and dose-response meta‑analysis.

    Rezaei Ahvanooei, M R / Norouzian, M A / Piray, A H / Vahmani, P / Ghaffari, M H

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 568

    Abstract: The aim of this study was to conduct a comprehensive review with meta-analysis to determine the effects of the dose-response relationship between monensin supplementation and dairy cow performance and milk composition. Results from 566 full-text articles ...

    Abstract The aim of this study was to conduct a comprehensive review with meta-analysis to determine the effects of the dose-response relationship between monensin supplementation and dairy cow performance and milk composition. Results from 566 full-text articles and 48 articles with 52 studies were meta-analyzed for pooled estimates. Monensin supplementation up to 23 ppm increased milk production, with the optimal dose being 12.6 ppm. Monensin supplementation at doses ranging from 16 to 96 ppm increased milk production in the prepartum phase (- 28 to 0 day relative to calving). From 60 to 150 DIM, monensin supplementation up to 21 ppm had a significant positive effect on this outcome, while supplementation in the 37 to 96 ppm range caused a decrease in this variable. At 0 to 60 and > 150 DIM, monensin supplementation had no effect on milk yield. At dosages of 22 to 96 ppm, 12 to 36 ppm, and below 58 ppm and 35 ppm, respectively, monensin supplementation resulted in significant decreases in dry matter intake (DMI), milk protein percentage, milk fat percentage, and milk fat yield. Overall, based on the results of this meta-analysis and considering all variables, the recommended optimal dose of monensin could be about 16 ppm.
    MeSH term(s) Animals ; Cattle ; Female ; Diet/veterinary ; Dietary Supplements ; Lactation/drug effects ; Milk/chemistry ; Milk Proteins/analysis ; Monensin/administration & dosage ; Monensin/pharmacology ; Dose-Response Relationship, Drug ; Fats/analysis
    Chemical Substances Milk Proteins ; Monensin (906O0YJ6ZP) ; Fats
    Language English
    Publishing date 2023-01-11
    Publishing country England
    Document type Systematic Review ; Meta-Analysis ; Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-27395-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Effects of monensin supplementation on rumen fermentation, methane emissions, nitrogen balance, and metabolic responses of dairy cows: A systematic review and dose-response meta-analysis.

    Rezaei Ahvanooei, M R / Norouzian, M A / Piray, A H / Vahmani, P / Ghaffari, M H

    Journal of dairy science

    2023  Volume 107, Issue 1, Page(s) 607–624

    Abstract: To investigate the effects of supplemental monensin administration on the metabolic responses of dairy cows, a systematic review and dose-response meta-analysis were conducted. Initially, 604 studies were identified through comprehensive database ... ...

    Abstract To investigate the effects of supplemental monensin administration on the metabolic responses of dairy cows, a systematic review and dose-response meta-analysis were conducted. Initially, 604 studies were identified through comprehensive database searches, including Google Scholar, Scopus, Science Direct, and PubMed, using key words related to dairy cows, monensin, and metabolic outcomes. After a 2-stage screening process, 51 articles with a total of 60 experiments were selected for meta-analysis based on criteria such as study implementation date between 2001 and 2022, presence of a control group that did not receive monensin supplementation, reporting of at least 1 outcome variable, and presentation of means and corresponding errors. The meta-analysis used the 1-stage random-effects method, and sensitivity analyses were performed to assess the robustness of the results. The results showed that the administration of monensin at a dosage of 19 to 26 mg/kg was inversely related to methane emissions and that the administration of monensin at a dosage of 18 to 50 mg/kg resulted in a significant decrease in dry matter intake. Administration of monensin at doses of 13 to 28 and 15 to 24 mg/kg also resulted in a significant decrease in ruminal acetate proportion and an increase in propionate proportion, respectively, with no effects on ruminal butyrate, NH
    MeSH term(s) Female ; Cattle ; Animals ; Monensin ; Milk/chemistry ; Fermentation ; Methane/metabolism ; Rumen/metabolism ; Nitrogen/metabolism ; Dietary Supplements/analysis ; Diet/veterinary ; Lactation/physiology
    Chemical Substances Monensin (906O0YJ6ZP) ; Methane (OP0UW79H66) ; Nitrogen (N762921K75)
    Language English
    Publishing date 2023-09-13
    Publishing country United States
    Document type Systematic Review ; Meta-Analysis ; Journal Article
    ZDB-ID 242499-x
    ISSN 1525-3198 ; 0022-0302
    ISSN (online) 1525-3198
    ISSN 0022-0302
    DOI 10.3168/jds.2023-23441
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Beneficial Effects of Vitamins, Minerals, and Bioactive Peptides on Strengthening the Immune System Against COVID-19 and the Role of Cow's Milk in the Supply of These Nutrients.

    Ahvanooei, M R Rezaei / Norouzian, Mohammad Ali / Vahmani, Payam

    Biological trace element research

    2021  Volume 200, Issue 11, Page(s) 4664–4677

    Abstract: The COVID-19 pandemic, which causes severe respiratory tract infections in humans, has become a global health concern and is spreading rapidly. At present, the most important issue associated with COVID-19 is the immune system and the factors that affect ...

    Abstract The COVID-19 pandemic, which causes severe respiratory tract infections in humans, has become a global health concern and is spreading rapidly. At present, the most important issue associated with COVID-19 is the immune system and the factors that affect it. It is well known that cow's milk is highly rich in micronutrients that increase and strengthen the immune system. Research shows that the administration of these nutrients is very effective in fighting COVID-19, and a deficiency in any of them can be a weakness in the fight against the virus. On the other hand, cow's milk is accessible to the whole population, and drinking colostrum, raw, and micro-filtered milk from cows vaccinated against SARS-CoV-2 could provide individuals with short-term protection against the SARS-CoV-2 infection until vaccines become commercially available. This review aimed to discuss the effects of milk vitamins, minerals, and bioactive peptides on general health in humans to combat viral diseases, especially COVID-19, and to what extent cow's milk consumption plays a role in providing these metabolites. Cow's milk contains many bioactive compounds that include vitamins, minerals, biogenic amines, nucleotides, oligosaccharides, organic acids, and immunoglobulins. Humans can meet a significant portion of their requirements for vitamins and minerals through the consumption of cow's milk. Recent studies have shown that micronutrients such as vitamins D, E, B, C, and A as well as minerals Zn, Cu, Mg, I, and Se and bioactive peptides, each can have positive and significant effects on strengthening the immune system and general health in humans.
    MeSH term(s) Animals ; COVID-19/prevention & control ; Cattle ; Female ; Humans ; Immune System ; Milk ; Minerals ; Nucleotides ; Pandemics ; Peptides ; SARS-CoV-2 ; Vitamin A ; Vitamins
    Chemical Substances Minerals ; Nucleotides ; Peptides ; Vitamins ; Vitamin A (11103-57-4)
    Language English
    Publishing date 2021-11-27
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 445336-0
    ISSN 1559-0720 ; 0163-4984
    ISSN (online) 1559-0720
    ISSN 0163-4984
    DOI 10.1007/s12011-021-03045-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Beneficial Effects of Vitamins, Minerals, and Bioactive Peptides on Strengthening the Immune System Against COVID-19 and the Role of Cow’s Milk in the Supply of These Nutrients

    Ahvanooei, M. R. Rezaei / Norouzian, Mohammad Ali / Vahmani, Payam

    Biological trace element research. 2022 Nov., v. 200, no. 11

    2022  

    Abstract: The COVID-19 pandemic, which causes severe respiratory tract infections in humans, has become a global health concern and is spreading rapidly. At present, the most important issue associated with COVID-19 is the immune system and the factors that affect ...

    Abstract The COVID-19 pandemic, which causes severe respiratory tract infections in humans, has become a global health concern and is spreading rapidly. At present, the most important issue associated with COVID-19 is the immune system and the factors that affect it. It is well known that cow’s milk is highly rich in micronutrients that increase and strengthen the immune system. Research shows that the administration of these nutrients is very effective in fighting COVID-19, and a deficiency in any of them can be a weakness in the fight against the virus. On the other hand, cow’s milk is accessible to the whole population, and drinking colostrum, raw, and micro-filtered milk from cows vaccinated against SARS-CoV-2 could provide individuals with short-term protection against the SARS-CoV-2 infection until vaccines become commercially available. This review aimed to discuss the effects of milk vitamins, minerals, and bioactive peptides on general health in humans to combat viral diseases, especially COVID-19, and to what extent cow’s milk consumption plays a role in providing these metabolites. Cow’s milk contains many bioactive compounds that include vitamins, minerals, biogenic amines, nucleotides, oligosaccharides, organic acids, and immunoglobulins. Humans can meet a significant portion of their requirements for vitamins and minerals through the consumption of cow’s milk. Recent studies have shown that micronutrients such as vitamins D, E, B, C, and A as well as minerals Zn, Cu, Mg, I, and Se and bioactive peptides, each can have positive and significant effects on strengthening the immune system and general health in humans.
    Keywords COVID-19 infection ; Severe acute respiratory syndrome coronavirus 2 ; colostrum ; cows ; immune system ; immunoglobulins ; metabolites ; milk ; milk consumption ; nucleotides ; oligosaccharides ; peptides ; research ; respiratory system ; trace elements ; viruses
    Language English
    Dates of publication 2022-11
    Size p. 4664-4677.
    Publishing place Springer US
    Document type Article
    Note Review
    ZDB-ID 445336-0
    ISSN 1559-0720 ; 0163-4984
    ISSN (online) 1559-0720
    ISSN 0163-4984
    DOI 10.1007/s12011-021-03045-x
    Database NAL-Catalogue (AGRICOLA)

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  6. Article ; Online: Effect of potassium iodide supplementation and teat-dipping on iodine status in dairy cows and milk iodine levels.

    Rezaei Ahvanooei, M R / Norouzian, M A / Hedayati, M / Vahmani, P

    Domestic animal endocrinology

    2020  Volume 74, Page(s) 106504

    Abstract: Two experiments were designed to determine the effects of dietary iodine and teat-dipping on the iodine status of dairy cows and their milk. Eight mid-lactation Holstein dairy cows with an initial body weight of 642 ± 62 kg and 145 ± 21 d in milk were ... ...

    Abstract Two experiments were designed to determine the effects of dietary iodine and teat-dipping on the iodine status of dairy cows and their milk. Eight mid-lactation Holstein dairy cows with an initial body weight of 642 ± 62 kg and 145 ± 21 d in milk were studied for 2 periods over 44 d. In period 1, all cows were fed a basal diet supplemented with potassium iodide (KI) (10 mg I/Kg DM) for 8 d with no teat-dipping. In period 2, a pre-milking teat-dipping was applied for 10 d followed by no teat-dipping before milking (udder wash without iodine) and then post-dipping treatment was applied for 5 d. Feeding KI increased concentrations of iodine in serum, urine, and milk (P < 0.05). Switching from the KI supplementation to no iodine addition resulted in an immediate decrease of iodine in serum, urine, and milk (P < 0.05). Post teat-dipping resulted in increased iodine levels in serum, urine, and milk (P < 0.05). However, pre-milking teat-dipping did not affect iodine concentration compared to post-dipping. A 250 mL cup of milk from the control and KI-supplemented diets would provide 29.4% and 68.4%, respectively, of the adult-recommended dietary allowance for iodine. In conclusion, milk iodine concentration could be effectively enhanced by KI supplementation and teat-dipping practices.
    MeSH term(s) Animals ; Cattle/physiology ; Dairying/methods ; Diet/veterinary ; Dietary Supplements ; Disinfectants/administration & dosage ; Female ; Iodine/administration & dosage ; Iodine/analysis ; Iodine/deficiency ; Mammary Glands, Animal/drug effects ; Milk/chemistry ; Nutritional Status ; Potassium Iodide/administration & dosage
    Chemical Substances Disinfectants ; Potassium Iodide (1C4QK22F9J) ; Iodine (9679TC07X4)
    Language English
    Publishing date 2020-06-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 594468-5
    ISSN 1879-0054 ; 0739-7240
    ISSN (online) 1879-0054
    ISSN 0739-7240
    DOI 10.1016/j.domaniend.2020.106504
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Effect of potassium iodide supplementation and teat-dipping on iodine status in dairy cows and milk iodine levels

    Rezaei Ahvanooei, M.R / Norouzian, M.A / Hedayati, M / Vahmani, P

    Domestic animal endocrinology. 2021 Jan., v. 74

    2021  

    Abstract: Two experiments were designed to determine the effects of dietary iodine and teat-dipping on the iodine status of dairy cows and their milk. Eight mid-lactation Holstein dairy cows with an initial body weight of 642 ± 62 kg and 145 ± 21 d in milk were ... ...

    Abstract Two experiments were designed to determine the effects of dietary iodine and teat-dipping on the iodine status of dairy cows and their milk. Eight mid-lactation Holstein dairy cows with an initial body weight of 642 ± 62 kg and 145 ± 21 d in milk were studied for 2 periods over 44 d. In period 1, all cows were fed a basal diet supplemented with potassium iodide (KI) (10 mg I/Kg DM) for 8 d with no teat-dipping. In period 2, a pre-milking teat-dipping was applied for 10 d followed by no teat-dipping before milking (udder wash without iodine) and then post-dipping treatment was applied for 5 d. Feeding KI increased concentrations of iodine in serum, urine, and milk (P < 0.05). Switching from the KI supplementation to no iodine addition resulted in an immediate decrease of iodine in serum, urine, and milk (P < 0.05). Post teat-dipping resulted in increased iodine levels in serum, urine, and milk (P < 0.05). However, pre-milking teat-dipping did not affect iodine concentration compared to post-dipping. A 250 mL cup of milk from the control and KI-supplemented diets would provide 29.4% and 68.4%, respectively, of the adult-recommended dietary allowance for iodine. In conclusion, milk iodine concentration could be effectively enhanced by KI supplementation and teat-dipping practices.
    Keywords Holstein ; blood serum ; body weight ; diet ; endocrinology ; iodine ; milk ; potassium iodide ; udders ; urine
    Language English
    Dates of publication 2021-01
    Publishing place Elsevier Inc.
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 594468-5
    ISSN 1879-0054 ; 0739-7240
    ISSN (online) 1879-0054
    ISSN 0739-7240
    DOI 10.1016/j.domaniend.2020.106504
    Database NAL-Catalogue (AGRICOLA)

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