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  1. Article ; Online: Letter to the Editor regarding: A review of recent compound-specific isotope analysis studies applied to food authentication.

    Salouros, Helen / Carter, James F / Dunn, Philip J H / Doyle, Sean P G

    Food chemistry

    2023  Volume 428, Page(s) 136776

    MeSH term(s) Food ; Carbon Isotopes/analysis ; Food Analysis
    Chemical Substances Carbon Isotopes
    Language English
    Publishing date 2023-07-01
    Publishing country England
    Document type Review ; Letter ; Comment
    ZDB-ID 243123-3
    ISSN 1873-7072 ; 0308-8146
    ISSN (online) 1873-7072
    ISSN 0308-8146
    DOI 10.1016/j.foodchem.2023.136776
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: An Integrated Experimental-Computational Study of Vocal Fold Vibration in Type I Thyroplasty.

    Avhad, Amit / Wilson, Azure / Sayce, Lea / Li, Zheng / Rousseau, Bernard / Doyle, James F / Luo, Haoxiang

    Journal of biomechanical engineering

    2024  Volume 146, Issue 4

    Abstract: Subject-specific computational modeling of vocal fold (VF) vibration was integrated with an ex vivo animal experiment of type 1 thyroplasty to study the effect of the implant on the vocal fold vibration. In the experiment, a rabbit larynx was used to ... ...

    Abstract Subject-specific computational modeling of vocal fold (VF) vibration was integrated with an ex vivo animal experiment of type 1 thyroplasty to study the effect of the implant on the vocal fold vibration. In the experiment, a rabbit larynx was used to simulate type 1 thyroplasty, where one side of the vocal fold was medialized with a trans-muscular suture while the other side was medialized with a silastic implant. Vocal fold vibration was then achieved by flowing air through the larynx and was filmed with a high-speed camera. The three-dimensional computational model was built upon the pre-operative scan of the laryngeal anatomy. This subject-specific model was used to simulate the vocal fold medialization and then the fluid-structure interaction (FSI) of the vocal fold. Model validation was done by comparing the vocal fold displacement with postoperative scan (for medialization), and by comparing the vibratory characteristics with the high-speed images (for vibration). These comparisons showed the computational model successfully captured the effect of the implant and thus has the potential for presurgical planning.
    MeSH term(s) Rabbits ; Animals ; Vocal Cords ; Laryngoplasty/methods ; Vocal Cord Paralysis/surgery ; Vibration ; Larynx/surgery
    Language English
    Publishing date 2024-02-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 243094-0
    ISSN 1528-8951 ; 0148-0731
    ISSN (online) 1528-8951
    ISSN 0148-0731
    DOI 10.1115/1.4064662
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: The life and work of Harvey Cushing 1869-1939: A pioneer of neurosurgery.

    Doyle, Nancileigh M / Doyle, James F / Walter, Edward J

    Journal of the Intensive Care Society

    2016  Volume 18, Issue 2, Page(s) 157–158

    Language English
    Publishing date 2016-10-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2701626-2
    ISSN 1751-1437 ; 1751-1437
    ISSN (online) 1751-1437
    ISSN 1751-1437
    DOI 10.1177/1751143716673076
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book: Nonlinear structural dynamics using FE methods

    Doyle, James F

    2015  

    Title variant Finite-element
    Author's details James F. Doyle
    Keywords Finite element method ; Nonlinear theories ; Structural analysis (Engineering)/Mathematics
    Language English
    Size XIV, 622 S., Ill., graph. Darst., 27 cm
    Publisher Cambridge Univ. Press
    Publishing place New York, NY
    Document type Book
    Note Author: James F. Doyle (professor in the School of Aeronautics and Astronautics at Purdue University) ; Includes bibliographical references and index
    ISBN 9781107045705 ; 1107045703
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  5. Article ; Online: Should we treat pyrexia? And how do we do it?

    Doyle, James F / Schortgen, Frédérique

    Critical care (London, England)

    2016  Volume 20, Issue 1, Page(s) 303

    Abstract: The concept of pyrexia as a protective physiological response to aid in host defence has been challenged with the awareness of the severe metabolic stress induced by pyrexia. The host response to pyrexia varies, however, according to the disease profile ... ...

    Abstract The concept of pyrexia as a protective physiological response to aid in host defence has been challenged with the awareness of the severe metabolic stress induced by pyrexia. The host response to pyrexia varies, however, according to the disease profile and severity and, as such, the management of pyrexia should differ; for example, temperature control is safe and effective in septic shock but remains controversial in sepsis. From the reported findings discussed in this review, treating pyrexia appears to be beneficial in septic shock, out of hospital cardiac arrest and acute brain injury.Multiple therapeutic options are available for managing pyrexia, with precise targeted temperature management now possible. Notably, the use of pharmacotherapy versus surface cooling has not been shown to be advantageous. The importance of avoiding hypothermia in any treatment strategy is not to be understated.Whilst a great deal of progress has been made regarding optimal temperature management in recent years, further studies will be needed to determine which patients would benefit the most from control of pyrexia and by which means this should be implemented. This narrative review is part of a series on the pathophysiology and management of pyrexia.
    Language English
    Publishing date 2016-10-03
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 2051256-9
    ISSN 1466-609X ; 1466-609X
    ISSN (online) 1466-609X
    ISSN 1466-609X
    DOI 10.1186/s13054-016-1467-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Interventions for improving outcomes in acute kidney injury.

    Sarnowski, Alexander / Doyle, James F / Forni, Lui G

    Current opinion in nephrology and hypertension

    2019  Volume 28, Issue 6, Page(s) 567–572

    Abstract: Purpose of review: Since the adoption of the classification of acute kidney injury (AKI) through changes in serum creatinine and/or urine output, much data have accumulated as to the associated risks in terms of morbidity and mortality after the ... ...

    Abstract Purpose of review: Since the adoption of the classification of acute kidney injury (AKI) through changes in serum creatinine and/or urine output, much data have accumulated as to the associated risks in terms of morbidity and mortality after the development of AKI. However, until recently, a nihilistic approach persisted which implied that little could be done to alter the clinical course of a patient with AKI even where early identification was achieved. This view is reinforced by the opinion that given the broad cause underlying the syndrome of AKI, a 'one size fits all' approach is unlikely to be successful.
    Recent findings: Recent evidence suggests that the management of AKI may be improved somewhat by simple measures, such as the use of care bundles particularly in the intensive care setting. Moreover, there are other interventions using common treatments, which may prove to be of benefit as well as some early evidence that specific therapeutics may be on the horizon.
    Summary: Although a syndrome of significantly differing causes, the application of standardized care bundles appears promising and this approach may be improved by the use of specific therapies, including recombinant alkaline phosphatase, the use of intravenous bicarbonate and remote ischaemic preconditioning may also ameliorate the effects of AKI.
    MeSH term(s) Acute Kidney Injury/therapy ; Alkaline Phosphatase/therapeutic use ; Humans ; Ischemic Preconditioning ; Sodium Bicarbonate/therapeutic use
    Chemical Substances Sodium Bicarbonate (8MDF5V39QO) ; Alkaline Phosphatase (EC 3.1.3.1)
    Language English
    Publishing date 2019-10-10
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1151092-4
    ISSN 1473-6543 ; 1535-3842 ; 1062-4813 ; 1062-4821
    ISSN (online) 1473-6543 ; 1535-3842
    ISSN 1062-4813 ; 1062-4821
    DOI 10.1097/MNH.0000000000000552
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Water Networks in Photosystem II Using Crystalline Molecular Dynamics Simulations and Room-Temperature XFEL Serial Crystallography.

    Doyle, Margaret D / Bhowmick, Asmit / Wych, David C / Lassalle, Louise / Simon, Philipp S / Holton, James / Sauter, Nicholas K / Yachandra, Vittal K / Kern, Jan F / Yano, Junko / Wall, Michael E

    Journal of the American Chemical Society

    2023  Volume 145, Issue 27, Page(s) 14621–14635

    Abstract: Structural dynamics of water and its hydrogen-bonding networks play an important role in enzyme function via the transport of protons, ions, and substrates. To gain insights into these mechanisms in the water oxidation reaction in Photosystem II (PS II), ...

    Abstract Structural dynamics of water and its hydrogen-bonding networks play an important role in enzyme function via the transport of protons, ions, and substrates. To gain insights into these mechanisms in the water oxidation reaction in Photosystem II (PS II), we have performed crystalline molecular dynamics (MD) simulations of the dark-stable S
    Language English
    Publishing date 2023-06-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.3c01412
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Waist-to-Hip Ratio as Supernormal Stimuli: Effect of Contrapposto Pose and Viewing Angle.

    Pazhoohi, Farid / Macedo, Antonio F / Doyle, James F / Arantes, Joana

    Archives of sexual behavior

    2019  Volume 49, Issue 3, Page(s) 837–847

    Abstract: In women, the waist-to-hip ratio (WHR) is an indicator of attractiveness, health, youthfulness, and reproductive potential. In the current study, we hypothesized that viewing angle and body postures influence the attractiveness of these forms based on ... ...

    Abstract In women, the waist-to-hip ratio (WHR) is an indicator of attractiveness, health, youthfulness, and reproductive potential. In the current study, we hypothesized that viewing angle and body postures influence the attractiveness of these forms based on the view dependency of WHR stimuli (vdWHR). Using eye tracking, we quantified the number of fixations and dwell time on 3D images of a female avatar in two different poses (standing and contrapposto) from eight viewing angles incrementing in 45 degrees of rotation. A total of 68 heterosexual individuals (25 men and 43 women) participated in the study. Results showed that the contrapposto pose was perceived as more attractive than the standing pose and that lower vdWHR sides of the stimuli attracted more first fixation, total fixations, and dwell time. Overall, the results supported that WHR is view-dependent and vdWHRs lower than optimal WHRs are supernormal stimuli that may generate peak shifts in responding. Results are discussed in terms of the attractiveness of women's movements (gaits and dance) and augmented artistic presentations.
    MeSH term(s) Adult ; Female ; Humans ; Male ; Waist-Hip Ratio/methods ; Young Adult
    Language English
    Publishing date 2019-06-18
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 184221-3
    ISSN 1573-2800 ; 0004-0002
    ISSN (online) 1573-2800
    ISSN 0004-0002
    DOI 10.1007/s10508-019-01486-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Update on sepsis-associated acute kidney injury: emerging targeted therapies.

    Doyle, James F / Forni, Lui G

    Biologics : targets & therapy

    2016  Volume 10, Page(s) 149–156

    Abstract: Sepsis-associated acute kidney injury (SA-AKI) is an independent predictor of increased mortality and morbidity. It is essential that further advances in the treatment of sepsis should prioritize targeted therapies in SA-AKI in order to improve these ... ...

    Abstract Sepsis-associated acute kidney injury (SA-AKI) is an independent predictor of increased mortality and morbidity. It is essential that further advances in the treatment of sepsis should prioritize targeted therapies in SA-AKI in order to improve these bleak outcomes. As yet, a unique therapy that effectively reduces the impact of acute kidney injury has not been demonstrated. However, the emergence of novel targeted therapies, perhaps in combination, has the possibility of significantly reducing the long-term sequelae of an episode of SA-AKI. In this review, we will focus on the shared etiology of these conditions and how this is managed with targeted therapy and finally the emerging novel therapies that may play an additional role to current treatment strategies.
    Language English
    Publishing date 2016-11-07
    Publishing country New Zealand
    Document type Review ; Journal Article
    ZDB-ID 2415708-9
    ISSN 1177-5491 ; 1177-5475
    ISSN (online) 1177-5491
    ISSN 1177-5475
    DOI 10.2147/BTT.S87385
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: An introduction to the FIRMS 2013 conference special edition of science and justice.

    Carter, James F / Doyle, Sean

    Science ; & ; justice : journal of the Forensic Science Society

    2015  Volume 55, Issue 1, Page(s) 1

    Language English
    Publishing date 2015-01
    Publishing country England
    Document type Editorial
    ZDB-ID 1230910-2
    ISSN 1876-4452 ; 1355-0306
    ISSN (online) 1876-4452
    ISSN 1355-0306
    DOI 10.1016/j.scijus.2014.10.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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