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Book ; Online ; E-Book: Cultures of oral health

Jones, Claire L. / Gibson, Barry

discourses, practices and theory

2023

Abstract: Oral health is integral to well-being and quality of life. This important edited volume brings together leading scholars to address global oral health and the multiple ways in which theory, practice and discourse have shaped it in the modern period. ... ...

Author's details	edited by Claire L. Jones and Barry J. Gibson
Abstract	"Oral health is integral to well-being and quality of life. This important edited volume brings together leading scholars to address global oral health and the multiple ways in which theory, practice and discourse have shaped it in the modern period. Drawing on perspectives from dentistry, sociology, history and the wider humanities, this book will interest students and researchers of dentistry, public health, sociology of health and illness, the medical humanities and history"--
Keywords	Dentistry/Social aspects
Subject code	617.6
Language	English
Size	1 online resource (261 pages)
Publisher	Routledge
Publishing place	London, England ; New York, New York
Document type	Book ; Online ; E-Book
Remark	Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
ISBN	1-00-304767-X ; 1-000-60432-2 ; 1-003-04767-X ; 0-367-49851-0 ; 978-1-00-304767-4 ; 978-1-000-60432-0 ; 978-1-003-04767-4 ; 978-0-367-49851-1
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article ; Online: Low-Barrier Buprenorphine Treatment for People Experiencing Homelessness.

Gibson, Claire L / Lo, Emma

Psychiatric services (Washington, D.C.)

2022 Volume 74, Issue 1, Page(s) 104

MeSH term(s)	Humans ; Buprenorphine/therapeutic use ; Ill-Housed Persons ; Social Problems ; Opioid-Related Disorders/drug therapy ; Opiate Substitution Treatment ; Analgesics, Opioid/therapeutic use
Chemical Substances	Buprenorphine (40D3SCR4GZ) ; Analgesics, Opioid
Language	English
Publishing date	2022-10-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	1220173-x
ISSN	1557-9700 ; 1075-2730
ISSN (online)	1557-9700
ISSN	1075-2730
DOI	10.1176/appi.ps.20220426
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Zs.A 416: Show issues

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Article ; Online: A review of experimental models of focal cerebral ischemia focusing on the middle cerebral artery occlusion model.

Trotman-Lucas, Melissa / Gibson, Claire L

F1000Research

2021 Volume 10, Page(s) 242

Abstract: Cerebral ischemic stroke is a leading cause of death and disability, but current pharmacological therapies are limited in their utility and effectiveness. ...

Abstract	Cerebral ischemic stroke is a leading cause of death and disability, but current pharmacological therapies are limited in their utility and effectiveness.
Language	English
Publishing date	2021-03-26
Publishing country	England
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	2699932-8
ISSN	2046-1402 ; 2046-1402
ISSN (online)	2046-1402
ISSN	2046-1402
DOI	10.12688/f1000research.51752.2
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Sexual dimorphism following in vitro ischemia in the response to neurosteroids and mechanisms of injury.

Altaee, Raeed / Gibson, Claire L

BMC neuroscience

2020 Volume 21, Issue 1, Page(s) 5

Abstract: Background: Cerebral ischemic stroke is a significant cause of morbidity and mortality. Sex differences exist following stroke in terms of incidence, symptoms, outcomes and response to some treatments. Importantly, molecular mechanisms of injury, ... ...

Abstract	Background: Cerebral ischemic stroke is a significant cause of morbidity and mortality. Sex differences exist following stroke in terms of incidence, symptoms, outcomes and response to some treatments. Importantly, molecular mechanisms of injury, activated following ischemia may differ between the sexes and if so may account, at least in part, for sex differences seen in treatment response. Here we aimed to determine, using single-sex organotypic hippocampal slice cultures, whether the effectiveness of a potential treatment option, i.e. sex steroids, exhibited any sexual dimorphism and whether sex affected the mechanisms of apoptosis activated following ischemia. Results: Following exposure to ischemia, male-derived tissue exhibited higher levels of cell death than female-derived tissue. Various sex steroid hormones, i.e. progesterone, allopregnanolone, and estradiol, were protective in terms of reducing the amount of cell death in male- and female-derived tissue whereas medoxyprogesterone acetate (MPA) was only protective in female-derived tissue. The protective effect of progesterone was abolished in the presence of finasteride, a 5α-reductase inhibitor, suggesting it was largely mediated via its conversion to allopregnanolone. To test the hypothesis that sex differences exist in the activation of specific elements of the apoptotic pathway activated following ischemia we administered Q-VD-OPH, a caspase inhibitor, or PJ34, an inhibitor of poly (ADP ribose) polymerase (PARP). Caspase inhibition was only effective, in terms of reducing cell death, in female-derived tissue, whereas PARP inhibition was only protective in male-derived tissue. However, in both sexes, the protective effects of progesterone and estradiol were not observed in the presence of either caspase or PARP inhibition. Conclusions: Sex differences exist in both the amount of cell death produced and those elements of the cell death pathway activated following an ischemic insult. There are also some sex differences in the effectiveness of steroid hormones to provide neuroprotection following an ischemic insult-namely MPA was only protective in female-derived tissue. This adds further support to the notion sex is an important factor to consider when investigating future drug targets for CNS disorders, such as ischemic stroke.
MeSH term(s)	Animals ; Apoptosis/drug effects ; Apoptosis Regulatory Proteins/drug effects ; Apoptosis Regulatory Proteins/metabolism ; Brain Ischemia/metabolism ; Female ; Hippocampus/drug effects ; Hippocampus/metabolism ; Male ; Mice, Inbred C57BL ; Neuroprotective Agents/administration & dosage ; Neurosteroids/administration & dosage ; Organ Culture Techniques ; Sex Characteristics ; Stroke/metabolism
Chemical Substances	Apoptosis Regulatory Proteins ; Neuroprotective Agents ; Neurosteroids
Language	English
Publishing date	2020-01-29
Publishing country	England
Document type	Journal Article
ISSN	1471-2202
ISSN (online)	1471-2202
DOI	10.1186/s12868-020-0553-1
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Social Cognition in Adolescents with Developmental Language Disorder (DLD): Evidence from the Social Attribution Task.

Forrest, Claire L / Lloyd-Esenkaya, Vanessa / Gibson, Jenny L / St Clair, Michelle C

Journal of autism and developmental disorders

2022 Volume 53, Issue 11, Page(s) 4243–4257

Abstract: Social cognition impairments may explain social, emotional and behavioural difficulties (SEBD) in individuals with Developmental Language Disorder (DLD). In a novel approach, the Social Attribution Task (SAT) was used to examine this association. SAT ... ...

Abstract	Social cognition impairments may explain social, emotional and behavioural difficulties (SEBD) in individuals with Developmental Language Disorder (DLD). In a novel approach, the Social Attribution Task (SAT) was used to examine this association. SAT narratives were coded from 53 participants [n = 26 DLD; n = 27 typical language development (TLD)] matched on age (M
MeSH term(s)	Humans ; Female ; Adolescent ; Male ; Social Cognition ; Language Development Disorders/psychology ; Autism Spectrum Disorder ; Cognition ; Language Development
Language	English
Publishing date	2022-08-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	391999-7
ISSN	1573-3432 ; 0162-3257
ISSN (online)	1573-3432
ISSN	0162-3257
DOI	10.1007/s10803-022-05698-6
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Article ; Online: A review of experimental models of focal cerebral ischemia focusing on the middle cerebral artery occlusion model [version 1; peer review

Melissa Trotman-Lucas / Claire L. Gibson

F1000Research, Vol

2 approved]

2021 Volume 10

Abstract: Cerebral ischemic stroke is a leading cause of death and disability, but current pharmacological therapies are limited in their utility and effectiveness. In vitro and in vivo models of ischemic stroke have been developed which allow us to further ... ...

Abstract	Cerebral ischemic stroke is a leading cause of death and disability, but current pharmacological therapies are limited in their utility and effectiveness. In vitro and in vivo models of ischemic stroke have been developed which allow us to further elucidate the pathophysiological mechanisms of injury and investigate potential drug targets. In vitro models permit mechanistic investigation of the biochemical and molecular mechanisms of injury but are reductionist and do not mimic the complexity of clinical stroke. In vivo models of ischemic stroke directly replicate the reduction in blood flow and the resulting impact on nervous tissue. The most frequently used in vivo model of ischemic stroke is the intraluminal suture middle cerebral artery occlusion (iMCAO) model, which has been fundamental in revealing various aspects of stroke pathology. However, the iMCAO model produces lesion volumes with large standard deviations even though rigid surgical and data collection protocols are followed. There is a need to refine the MCAO model to reduce variability in the standard outcome measure of lesion volume. The typical approach to produce vessel occlusion is to induce an obstruction at the origin of the middle cerebral artery and reperfusion is reliant on the Circle of Willis (CoW). However, in rodents the CoW is anatomically highly variable which could account for variations in lesion volume. Thus, we developed a refined approach whereby reliance on the CoW for reperfusion was removed. This approach improved reperfusion to the ischemic hemisphere, reduced variability in lesion volume by 30%, and reduced group sizes required to determine an effective treatment response by almost 40%. This refinement involves a methodological adaptation of the original surgical approach which we have shared with the scientific community via publication of a visualised methods article and providing hands-on training to other experimental stroke researchers.
Keywords	Medicine ; R ; Science ; Q
Subject code	610
Language	English
Publishing date	2021-03-01T00:00:00Z
Publisher	F1000 Research Ltd
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A review of experimental models of focal cerebral ischemia focusing on the middle cerebral artery occlusion model [version 2; peer review

Melissa Trotman-Lucas / Claire L. Gibson

F1000Research, Vol

2 approved]

2021 Volume 10

Abstract	Cerebral ischemic stroke is a leading cause of death and disability, but current pharmacological therapies are limited in their utility and effectiveness. In vitro and in vivo models of ischemic stroke have been developed which allow us to further elucidate the pathophysiological mechanisms of injury and investigate potential drug targets. In vitro models permit mechanistic investigation of the biochemical and molecular mechanisms of injury but are reductionist and do not mimic the complexity of clinical stroke. In vivo models of ischemic stroke directly replicate the reduction in blood flow and the resulting impact on nervous tissue. The most frequently used in vivo model of ischemic stroke is the intraluminal suture middle cerebral artery occlusion (iMCAO) model, which has been fundamental in revealing various aspects of stroke pathology. However, the iMCAO model produces lesion volumes with large standard deviations even though rigid surgical and data collection protocols are followed. There is a need to refine the MCAO model to reduce variability in the standard outcome measure of lesion volume. The typical approach to produce vessel occlusion is to induce an obstruction at the origin of the middle cerebral artery and reperfusion is reliant on the Circle of Willis (CoW). However, in rodents the CoW is anatomically highly variable which could account for variations in lesion volume. Thus, we developed a refined approach whereby reliance on the CoW for reperfusion was removed. This approach improved reperfusion to the ischemic hemisphere, reduced variability in lesion volume by 30%, and reduced group sizes required to determine an effective treatment response by almost 40%. This refinement involves a methodological adaptation of the original surgical approach which we have shared with the scientific community via publication of a visualised methods article and providing hands-on training to other experimental stroke researchers.
Keywords	Medicine ; R ; Science ; Q
Subject code	610
Language	English
Publishing date	2021-06-01T00:00:00Z
Publisher	F1000 Research Ltd
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Social Functioning as a Mediator between Developmental Language Disorder (DLD) and Emotional Problems in Adolescents.

Forrest, Claire L / Gibson, Jenny L / St Clair, Michelle C

International journal of environmental research and public health

2021 Volume 18, Issue 3

Abstract: Adolescents with Developmental Language Disorder (DLD) are at risk for increased feelings of anxiety and depression compared to their typically developing (TD) peers. However, the underlying pathways involved in this relationship are unclear. In this ... ...

Abstract	Adolescents with Developmental Language Disorder (DLD) are at risk for increased feelings of anxiety and depression compared to their typically developing (TD) peers. However, the underlying pathways involved in this relationship are unclear. In this initial study of the 'social mediation hypothesis', we examine social functioning as a mediator of emotional problems in a cross-sectional sample of adolescents with DLD and age- and sex-matched controls. Preliminary data from twenty-six participants with DLD and 27 participants with typical language development (TLD, 11-17 years) were compared on self- and parent-reported measures of social functioning and emotional outcomes. There was little evidence of group differences in self-reported social functioning and emotional outcomes, but parent-report of SDQ Peer Problems and Emotional Problems in the DLD group was significantly higher than in the TLD group. Parent-reported peer problems mediated parent-reported emotional problems, accounting for 69% of the relationship between DLD status and emotional problems. Parents of adolescents with DLD, but not adolescents themselves, report significantly higher peer and emotional problems compared to TLD peers. The hypotheses generated from these novel data suggest further investigation into adolescents' perceptions of socioemotional difficulties and friendships should be examined.
MeSH term(s)	Adolescent ; Cross-Sectional Studies ; Emotions ; Humans ; Language Development Disorders ; Social Adjustment ; Social Interaction
Language	English
Publishing date	2021-01-29
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1660-4601
ISSN (online)	1660-4601
DOI	10.3390/ijerph18031221
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Systematic Review of Antimicrobial Lock Solutions for Prevention of Bacteremia in Pediatric Patients With Intestinal Failure.

Gibson, Bridget / McNiven, Claire / Sebastianski, Meghan / Vandermeer, Ben / Persad, Rabin / Robinson, Joan L

Journal of pediatric gastroenterology and nutrition

2022 Volume 76, Issue 4, Page(s) 410–417

Abstract: Objectives: The goal of this systematic review was to determine whether antimicrobial lock (AML) solutions prevent catheter-related bloodstream infections (CRBSI) in children with intestinal failure (IF).: Methods: Electronic databases were searched: ...

Abstract	Objectives: The goal of this systematic review was to determine whether antimicrobial lock (AML) solutions prevent catheter-related bloodstream infections (CRBSI) in children with intestinal failure (IF). Methods: Electronic databases were searched: Ovid MEDLINE (1946-), Ovid Embase (1974-), Wiley Cochrane Library (inception-), and Web of Science Core Collection via Clarivate Analytics (1900-). Randomized and nonrandomized trials, case or cohort studies that studied any AML solution, and used comparator groups were included if they studied children with IF. A meta-analysis compared the rates of CRBSI with AML solutions versus controls, and a Boucher analysis was used to indirectly compare AML solutions. Results: Twenty-eight studies met eligibility criteria (1 open label and 27 observational studies). Quality was good (N = 13), fair (N = 9), and poor (N = 6). All but 4 studied ethanol and taurolidine. Of 15 ethanol studies, 11 reported a decrease and 3 reported a trend toward a decreased incidence of CRBSI compared to controls; 1 reported no difference. Of 9 taurolidine studies, 7 reported a decrease and 2 a trend toward decreased CRBSI rates. There was a decrease in CRBSI with ethanol versus control ( P = 0.008) and with taurolidine-citrate versus control ( P < 0.0005). Using Bucher indirect comparison of the pooled estimates from ethanol versus control to taurolidine versus control, the estimated difference was -0.99 (-4.125, 2.27; P = 0.55). Conclusions: There were no randomized trials and over half of the 28 included studies were fair or poor quality. All but 1 reported at least a trend toward reduction in CRBSI. AML solutions appear to prevent CRBSI.
MeSH term(s)	Humans ; Child ; Intestinal Failure ; Catheter-Related Infections/prevention & control ; Ethanol ; Bacteremia/prevention & control ; Bacteremia/complications ; Anti-Infective Agents ; Leukemia, Myeloid, Acute/complications ; Central Venous Catheters/adverse effects
Chemical Substances	taurolidine (8OBZ1M4V3V) ; Ethanol (3K9958V90M) ; Anti-Infective Agents
Language	English
Publishing date	2022-11-23
Publishing country	United States
Document type	Systematic Review ; Meta-Analysis ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	603201-1
ISSN	1536-4801 ; 0277-2116
ISSN (online)	1536-4801
ISSN	0277-2116
DOI	10.1097/MPG.0000000000003658
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Article ; Online: Synthesis of Chitosan-Silver Nanocomposite and Its Evaluation as an Antibacterial Coating for Mobile Phone Glass Protectors.

Canama, Gibson Jake C / Delco, Monica Claire L / Talandron, Rhoel A / Tan, Noel Peter

ACS omega

2023 Volume 8, Issue 20, Page(s) 17699–17711

Abstract: An easy and environment-friendly route for antibacterial coating suited for mobile phone glass protectors was successfully demonstrated. In this route, freshly prepared chitosan solution in 1% v/v acetic acid was added with 0.1 M silver nitrate solution ... ...

Abstract	An easy and environment-friendly route for antibacterial coating suited for mobile phone glass protectors was successfully demonstrated. In this route, freshly prepared chitosan solution in 1% v/v acetic acid was added with 0.1 M silver nitrate solution and 0.1 M sodium hydroxide solution and incubated with agitation at 70 °C to form chitosan-silver nanoparticles (ChAgNPs). Varied concentrations of chitosan solution (i.e., 0.1, 0.2, 0.4, 0.6, and 0.8% w/v) were used to investigate its particle size, size distribution, and later on, its antibacterial activity. Transmission electron microscope (TEM) imaging revealed that the smallest average diameter of silver nanoparticles (AgNPs) was 13.04 nm from 0.8% w/v chitosan solution. Further characterizations of the optimal nanocomposite formulation using UV-vis spectroscopy and Fourier transfer infrared spectroscopy were also performed. Using a dynamic light scattering zetasizer, the average ζ-potential of the optimal ChAgNP formulation was at +56.07 mV, showing high aggregative stability and an average ChAgNP size of 182.37 nm. The ChAgNP nanocoating on glass protectors shows antibacterial activity against
Language	English
Publishing date	2023-05-10
Publishing country	United States
Document type	Journal Article
ISSN	2470-1343
ISSN (online)	2470-1343
DOI	10.1021/acsomega.3c00191
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