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  1. Article ; Online: A risk-risk trade-off assessment of climate-induced mortality risk changes.

    Mussio, Irene / Chilton, Susan / Duxbury, Darren / Nielsen, Jytte Seested

    Risk analysis : an official publication of the Society for Risk Analysis

    2023  Volume 44, Issue 3, Page(s) 536–552

    Abstract: The impact of climate change on human health was identified as a priority for the UN COP26 conference. In this article, we consider climate-induced changes to mortality risks and how to incorporate these formally in the policy appraisal process. In the ... ...

    Abstract The impact of climate change on human health was identified as a priority for the UN COP26 conference. In this article, we consider climate-induced changes to mortality risks and how to incorporate these formally in the policy appraisal process. In the United Kingdom (UK), the Value of Statistical Life (VSL) is used to monetarize the benefits of policies to reduce mortality risks but it remains an open, empirical question as to whether the current VSL (£2.14 million per fatality prevented, December 2021 values) for traffic accidents should be applied in other contexts without any modification and particularly for extreme weather event fatalities. Using a representative sample of the UK population, we aim to estimate and better understand the trade-offs people make when comparing mortality risks, drawing on psychological insights from construal level and regulatory focus theories. We design a stated preference survey using a relative valuation framework with nonmonetary, risk-risk trade-off questions between extreme weather event and traffic accident mortality risks. We find evidence of an extreme weather event risk premium of 1.2-1.6 (implying a climate-related VSL of £2.52-£3.41 million). We also find that participants who are psychologically close to climate change (based on construal level theory), weigh reducing extreme weather event mortality risks almost two times that of reducing traffic accident mortality risks.
    MeSH term(s) Humans ; Accidents, Traffic ; Climate Change ; Policy ; Risk Assessment ; United Kingdom
    Language English
    Publishing date 2023-07-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 778660-8
    ISSN 1539-6924 ; 0272-4332
    ISSN (online) 1539-6924
    ISSN 0272-4332
    DOI 10.1111/risa.14185
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Beyond COVID-19: How the 'dismal science' can prepare us for the future.

    Chilton, Susan / Nielsen, Jytte Seested / Wildman, John

    Health economics

    2020  Volume 29, Issue 8, Page(s) 851–853

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/economics ; Coronavirus Infections/epidemiology ; Cost-Benefit Analysis ; Disaster Planning/economics ; Disaster Planning/organization & administration ; Global Health ; Health Care Rationing/organization & administration ; Humans ; Pandemics/economics ; Pneumonia, Viral/economics ; Pneumonia, Viral/epidemiology ; Quality-Adjusted Life Years ; SARS-CoV-2 ; United Kingdom/epidemiology
    Keywords covid19
    Language English
    Publishing date 2020-06-02
    Publishing country England
    Document type Editorial
    ZDB-ID 1135838-5
    ISSN 1099-1050 ; 1057-9230
    ISSN (online) 1099-1050
    ISSN 1057-9230
    DOI 10.1002/hec.4114
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Impact of

    Sergeant, Susan / Keith, Brian A / Seeds, Michael C / Legins, Jimaree A / Young, Caroline B / Vitolins, Mara Z / Chilton, Floyd H

    Frontiers in nutrition

    2023  Volume 10, Page(s) 1111624

    Abstract: Introduction: Polyunsaturated fatty acids (PUFA) and highly unsaturated fatty acid (HUFA) synthetic products and their signaling metabolites play vital roles in immunity, inflammation, and brain development/function. Frequency differences of variants ... ...

    Abstract Introduction: Polyunsaturated fatty acids (PUFA) and highly unsaturated fatty acid (HUFA) synthetic products and their signaling metabolites play vital roles in immunity, inflammation, and brain development/function. Frequency differences of variants within the fatty acid desaturase (
    Methods: Data and biospecimens (plasma, red blood cells, buffy coat-derived DNA) from 135 participants (83.7% female) were used to assess the relationship(s) between dietary PUFA levels, a
    Results: The dietary habits of the cohort showed that participant diets contained a high ratio (9.3 ± 0.2, mean ± SEM) of linoleic acid (
    Discussion: Taken together, this study illustrates that dietary PUFA + HUFA ×
    Language English
    Publishing date 2023-05-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2776676-7
    ISSN 2296-861X
    ISSN 2296-861X
    DOI 10.3389/fnut.2023.1111624
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Beyond COVID‐19

    Chilton, Susan / Nielsen, Jytte Seested / Wildman, John

    Health Economics

    How the ‘dismal science’ can prepare us for the future

    2020  Volume 29, Issue 8, Page(s) 851–853

    Keywords Health Policy ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    ZDB-ID 1135838-5
    ISSN 1057-9230
    ISSN 1057-9230
    DOI 10.1002/hec.4114
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Dietary Sources of Linoleic Acid (LA) Differ by Race/Ethnicity in Adults Participating in the National Health and Nutrition Examination Survey (NHANES) between 2017-2018.

    Momin, Shabnam R / Senn, Mackenzie K / Manichaikul, Ani / Yang, Chaojie / Mathias, Rasika / Phan, Mimi / Rich, Stephen S / Sergeant, Susan / Seeds, Michael / Reynolds, Lindsay / Chilton, Floyd H / Wood, Alexis C

    Nutrients

    2023  Volume 15, Issue 12

    Abstract: Linoleic acid (LA) is a ... ...

    Abstract Linoleic acid (LA) is a primary
    MeSH term(s) Humans ; Animals ; Linoleic Acid ; Nutrition Surveys ; Energy Intake ; Cross-Sectional Studies ; Ethnicity ; Diet ; Fruit ; Vegetables
    Chemical Substances Linoleic Acid (9KJL21T0QJ)
    Language English
    Publishing date 2023-06-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15122779
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Population health risks in multi-hazard environments: action needed in the Cyclone Amphan and COVID-19 – hit Sundarbans region, India

    Pramanik, Malay / Szabo, Sylvia / Pal, Indrajit / Udmale, Parmeshwar / Pongsiri, Montira / Chilton, Susan

    Climate and development. 2022 Feb. 07, v. 14, no. 2

    2022  

    Abstract: The local population of Sundarbans, an environmentally vulnerable delta region in south-eastern India, is currently affected by combined negative impacts of cyclone Amphan and the COVID-19 pandemic. The lockdown measures have created an additional burden ...

    Abstract The local population of Sundarbans, an environmentally vulnerable delta region in south-eastern India, is currently affected by combined negative impacts of cyclone Amphan and the COVID-19 pandemic. The lockdown measures have created an additional burden on the health care system, while flooding during Amphan increased the risk of spreading water-borne diseases. In this viewpoint, we provide a conceptual model of the complex interlinkages among the combined multi-hazard effects, human health and water availability, with possible mitigation measures. We then discuss the specific pathways through which these immediate and long-term impacts occur and highlight the risk of together slowing progress on SDG3 and SDG6 in the Sundarbans. Finally, we call for coordinated assessment, support and appropriate intervention measures to secure clean water availability and minimize the health impacts of the recent multiple disasters in this tropical delta region.
    Keywords COVID-19 infection ; climate ; health services ; human health ; models ; risk ; India
    Language English
    Dates of publication 2022-0207
    Size p. 99-104.
    Publishing place Taylor & Francis
    Document type Article
    ISSN 1756-5537
    DOI 10.1080/17565529.2021.1889948
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: Interpreting Clinical Trials With Omega-3 Supplements in the Context of Ancestry and

    Chilton, Floyd H / Manichaikul, Ani / Yang, Chaojie / O'Connor, Timothy D / Johnstone, Laurel M / Blomquist, Sarah / Schembre, Susan M / Sergeant, Susan / Zec, Manja / Tsai, Michael Y / Rich, Stephen S / Bridgewater, Susan J / Mathias, Rasika A / Hallmark, Brian

    Frontiers in nutrition

    2022  Volume 8, Page(s) 808054

    Abstract: Human diets in developed countries such as the US have changed dramatically over the past 75 years, leading to increased obesity, inflammation, and cardiometabolic dysfunction. Evidence over the past decade indicates that the interaction of genetic ... ...

    Abstract Human diets in developed countries such as the US have changed dramatically over the past 75 years, leading to increased obesity, inflammation, and cardiometabolic dysfunction. Evidence over the past decade indicates that the interaction of genetic variation with changes in the intake of 18-carbon essential dietary omega-6 (n-6) and omega-3 (n-3) polyunsaturated fatty acids (PUFA), linoleic acid (LA) and α-linolenic acid (ALA), respectively, has impacted numerous molecular and clinical phenotypes. Interactions are particularly relevant with the
    Language English
    Publishing date 2022-02-08
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2776676-7
    ISSN 2296-861X
    ISSN 2296-861X
    DOI 10.3389/fnut.2021.808054
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: A Novel Application of Risk-Risk Tradeoffs in Occupational Health: Nurses' Occupational Asthma and Infection Risk Perceptions Related to Cleaning and Disinfection during COVID-19.

    Wilson, Amanda M / Mussio, Irene / Chilton, Susan / Gerald, Lynn B / Jones, Rachael M / Drews, Frank A / LaKind, Judy S / Beamer, Paloma I

    International journal of environmental research and public health

    2022  Volume 19, Issue 23

    Abstract: Background: Nurses face the risk of new onset occupational asthma (OA) due to exposures to cleaning and disinfection (C&D) agents used to prevent infections in healthcare facilities. The objective of this study was to measure nurses' preferences when ... ...

    Abstract Background: Nurses face the risk of new onset occupational asthma (OA) due to exposures to cleaning and disinfection (C&D) agents used to prevent infections in healthcare facilities. The objective of this study was to measure nurses' preferences when presented with simultaneous OA and respiratory viral infection (e.g., COVID-19) risks related to increased/decreased C&D activities.
    Methods: Nurses working in healthcare for ≥1 year and without physician-diagnosed asthma were recruited for an online anonymous survey, including four risk-risk tradeoff scenarios between OA and respiratory infection with subsequent recovery (Infect and Recovery) or subsequent death (Infect and Death). Nurses were presented with baseline risks at hypothetical "Hospital 1", and were asked to choose Hospital 2 (increased OA risk to maintain infection risk), Hospital 3 (increased infection risk to maintain OA risk), or indicate that they were equally happy.
    Results: Over 70% of nurses were willing to increase infection risk to maintain baseline OA risk if they were confident they would recover from the infection. However, even when the risk of infection leading to death was much lower than OA, most nurses were not willing to accept a larger (but still small) risk of death to avoid doubling their OA risk. Age, work experience, and ever having contracted or knowing anyone who has contracted a respiratory viral infection at work influenced choices.
    Conclusions: We demonstrate the novel application of a risk-risk tradeoff framework to address an occupational health issue. However, more data are needed to test the generalizability of the risk preferences found in this specific risk-risk tradeoff context.
    MeSH term(s) Humans ; Occupational Health ; Occupational Exposure ; COVID-19/epidemiology ; COVID-19/prevention & control ; Asthma, Occupational ; Occupational Diseases/diagnosis ; Disease Susceptibility
    Language English
    Publishing date 2022-12-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph192316092
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Perspective: Council for Responsible Nutrition Science in Session. Optimizing Health with Nutrition-Opportunities, Gaps, and the Future.

    Ho, Emily / Drake, Victoria J / Michels, Alexander J / Nkrumah-Elie, Yasmeen M / Brown, LaVerne L / Scott, Jonathan M / Newman, John W / Shukitt-Hale, Barbara / Soumyanath, Amala / Chilton, Floyd H / Lindemann, Stephen R / Shao, Andrew / Mitmesser, Susan Hazels

    Advances in nutrition (Bethesda, Md.)

    2023  Volume 14, Issue 5, Page(s) 948–958

    Abstract: Achieving optimal health is an aspirational goal for the population, yet the definition of health remains unclear. The role of nutrition in health has evolved beyond correcting malnutrition and specific deficiencies and has begun to focus more on ... ...

    Abstract Achieving optimal health is an aspirational goal for the population, yet the definition of health remains unclear. The role of nutrition in health has evolved beyond correcting malnutrition and specific deficiencies and has begun to focus more on achieving and maintaining 'optimal' health through nutrition. As such, the Council for Responsible Nutrition held its October 2022 Science in Session conference to advance this concept. Here, we summarize and discuss the findings of their Optimizing Health through Nutrition - Opportunities and Challenges workshop, including several gaps that need to be addressed to advance progress in the field. Defining and evaluating various indices of optimal health will require overcoming these key gaps. For example, there is a strong need to develop better biomarkers of nutrient status, including more accurate markers of food intake, as well as biomarkers of optimal health that account for maintaining resilience-the ability to recover from or respond to stressors without loss to physical and cognitive performance. In addition, there is a need to identify factors that drive individualized responses to nutrition, including genotype, metabotypes, and the gut microbiome, and to realize the opportunity of precision nutrition for optimal health. This review outlines hallmarks of resilience, provides current examples of nutritional factors to optimize cognitive and performance resilience, and gives an overview of various genetic, metabolic, and microbiome determinants of individualized responses.
    MeSH term(s) Humans ; Nutritional Status ; Biomarkers ; Gastrointestinal Microbiome ; Nutritional Sciences
    Chemical Substances Biomarkers
    Language English
    Publishing date 2023-06-01
    Publishing country United States
    Document type Review ; Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2583634-1
    ISSN 2156-5376 ; 2156-5376
    ISSN (online) 2156-5376
    ISSN 2156-5376
    DOI 10.1016/j.advnut.2023.05.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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