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  1. Article ; Online: Use of antibiotics for acute sore throat and tonsillitis in primary care.

    Wilcox, Christopher R / Moore, Michael / Little, Paul

    The British journal of general practice : the journal of the Royal College of General Practitioners

    2022  Volume 72, Issue 716, Page(s) 136–137

    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Common Cold ; Humans ; Pharyngitis/drug therapy ; Primary Health Care ; Tonsillitis/drug therapy
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2022-02-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 1043148-2
    ISSN 1478-5242 ; 0035-8797 ; 0960-1643
    ISSN (online) 1478-5242
    ISSN 0035-8797 ; 0960-1643
    DOI 10.3399/bjgp22X718793
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 576: Show issues Location:
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    Zs.MO 100: Show issues

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  2. Article ; Online: Commentary: Myocardial infarction after cardiac surgery: Putting it all together.

    Wilcox, Christopher / Smith, Nikolhaus / Whitman, Glenn J R

    The Journal of thoracic and cardiovascular surgery

    2021  Volume 165, Issue 3, Page(s) 1203–1204

    MeSH term(s) Humans ; Myocardial Infarction/etiology ; Cardiac Surgical Procedures/adverse effects
    Language English
    Publishing date 2021-08-27
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 3104-5
    ISSN 1097-685X ; 0022-5223
    ISSN (online) 1097-685X
    ISSN 0022-5223
    DOI 10.1016/j.jtcvs.2021.08.055
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Generalizable turbulent flow forecasting for adaptive optics control.

    Shaffer, Benjamin D / Vorenberg, Jeremy R / Wilcox, Christopher C / McDaniel, Austin J

    Applied optics

    2023  Volume 62, Issue 23, Page(s) G1–G11

    Abstract: In this work, we characterize the capability of artificial neural network predictive models for generalizable turbulence forecasting, particularly for use in predictive adaptive optics (AO) applications. Predictive AO control, which utilizes future state ...

    Abstract In this work, we characterize the capability of artificial neural network predictive models for generalizable turbulence forecasting, particularly for use in predictive adaptive optics (AO) applications. Predictive AO control, which utilizes future state predictions of an optical wavefront propagated through a turbulent medium to drive correction, is a promising technology for optical propagation in high-disturbance and low-signal environments. The dynamics describing the evolution of turbulent flow can vary greatly. Accordingly, a generalizable approach to turbulence forecasting has key benefits in allowing for prediction across a range of conditions, thus enabling continuous predictive AO operation in dynamic environments and having reduced sensitivity to changes in conditions. We present a model for generalizable turbulence forecasting, which demonstrated consistent high performance over a range of compressible flow conditions outside those included in the training sample, with only a minimal increase in prediction error compared with a hypothetical baseline model, which assumes perfect a priori characterization. These results demonstrate a clear ability to extract useful dynamics from a limited domain of turbulent conditions and apply these appropriately for forecasting, which could inform future design of predictive AO systems.
    Language English
    Publishing date 2023-09-14
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4522
    ISSN (online) 1539-4522
    DOI 10.1364/AO.486236
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book: Therapy in nephrology and hypertension

    Brady, Hugh R. / Wilcox, Christopher S.

    a companion to Brenner and Rector's the kidney

    1999  

    Author's details Hugh R. Brady ; Christopher S. Wilcox
    Keywords Kidney Diseases / therapy ; Kidney Diseases / complications ; Urogenital Diseases / therapy ; Hypertension / therapy ; Nephrology / methods
    Language English
    Size XXVII, 717 S. : Ill., graph. Darst.
    Publisher Saunders
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index
    HBZ-ID HT010409192
    ISBN 0-7216-7149-7 ; 978-0-7216-7149-9
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    1999 A 3301 order for loan Magazin

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  5. Article ; Online: Current practice and attitudes towards vaccination during pregnancy: a survey of GPs across England

    Wilcox, Christopher R / Little, Paul / Jones, Christine E

    The British journal of general practice : the journal of the Royal College of General Practitioners

    2020  Volume 70, Issue 691, Page(s) e179–e185

    Language English
    Publishing date 2020-01-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 1043148-2
    ISSN 1478-5242 ; 0035-8797 ; 0960-1643
    ISSN (online) 1478-5242
    ISSN 0035-8797 ; 0960-1643
    DOI 10.3399/bjgp20X708113
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    In stock of ZB MED Cologne/Königswinter

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  6. Article: Beyond Passive Immunity: Is There Priming of the Fetal Immune System Following Vaccination in Pregnancy and What Are the Potential Clinical Implications?

    Wilcox, Christopher R / Jones, Christine E

    Frontiers in immunology

    2018  Volume 9, Page(s) 1548

    Abstract: Infection is responsible for over half a million neonatal deaths worldwide every year, and vaccination in pregnancy is becoming increasingly recognized as an important strategy for the protection of young infants. Increasing evidence suggests that ... ...

    Abstract Infection is responsible for over half a million neonatal deaths worldwide every year, and vaccination in pregnancy is becoming increasingly recognized as an important strategy for the protection of young infants. Increasing evidence suggests that exposure to maternal infection
    Language English
    Publishing date 2018-07-16
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2606827-8
    ISSN 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2018.01548
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  7. Article ; Online: Association between influenza vaccination and hospitalisation or all-cause mortality in people with COVID-19

    Hajira Dambha-Miller / Christopher R Wilcox

    BMJ Open Respiratory Research, Vol 8, Iss

    a retrospective cohort study

    2021  Volume 1

    Abstract: Introduction Recent evidence suggests that influenza vaccination may offer protection against COVID-19 severity. Our aim was to quantify the association between influenza vaccination status and risk of hospitalisation or all-cause mortality in people ... ...

    Abstract Introduction Recent evidence suggests that influenza vaccination may offer protection against COVID-19 severity. Our aim was to quantify the association between influenza vaccination status and risk of hospitalisation or all-cause mortality in people diagnosed with COVID-19.Methods A retrospective cohort study using routinely collected health records from patients registered to a General Practitioner (GP) practice in South West England within the Electronic Care and Health Information Analytics database. The cohort included 6921 people with COVID-19 during the first wave of the pandemic (1 January–31 July 2020). Data on influenza vaccination, hospitalisation and all-cause mortality were ascertained through linked clinical and demographic records. We applied propensity score methods (stabilised inverse probability of treatment weight) to quantify the association between influenza vaccination status and COVID-19 outcomes (hospitalisation or all-cause mortality).Results 2613 (38%) participants received an influenza vaccination between 1 January 2019 and COVID-19 diagnosis. Receipt of influenza vaccination was associated with a significantly lower odds of hospitalisation or all-cause mortality (adjusted OR: 0.85, 95% CI 0.75 to 0.97, p=0.02), and 24% reduced odds of all-cause mortality (adjusted OR: 0.76, 95% CI 0.64 to 0.90).Discussion Influenza vaccination was associated with a 15%–24% lower odds of severe COVID-19 outcomes. The current UK influenza vaccination programme needs urgent expansion as an integral component of the ongoing response plans to the COVID-19 pandemic.
    Keywords Medicine ; R ; Diseases of the respiratory system ; RC705-779
    Subject code 310
    Language English
    Publishing date 2021-08-01T00:00:00Z
    Publisher BMJ Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  8. Article ; Online: Racial and ethnical discrepancy in hypoxemia detection in patients on extracorporeal membrane oxygenation.

    Kalra, Andrew / Shou, Benjamin L / Zhao, David / Wilcox, Christopher / Keller, Steven P / Whitman, Glenn J R / Kim, Bo Soo / Cho, Sung-Min

    JTCVS open

    2023  Volume 14, Page(s) 145–170

    Abstract: Objective: To determine whether there is racial/ethnical discrepancy between pulse oximetry (SpO: Methods: This was a retrospective observational study at a tertiary academic ECMO center with adults (>18 years) on venoarterial (VA) or venovenous (VV) ...

    Abstract Objective: To determine whether there is racial/ethnical discrepancy between pulse oximetry (SpO
    Methods: This was a retrospective observational study at a tertiary academic ECMO center with adults (>18 years) on venoarterial (VA) or venovenous (VV) ECMO. Datapoints were excluded if oxygen saturation ≤70% or SpO
    Results: Of 139 patients receiving VA-ECMO and 57 patients receiving VV-ECMO, we examined 16,252 SpO
    Conclusions: SpO
    Language English
    Publishing date 2023-03-01
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2666-2736
    ISSN (online) 2666-2736
    DOI 10.1016/j.xjon.2023.02.011
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  9. Article ; Online: Extracorporeal Membrane Oxygenation Physiological Factors Influence Pulse Oximetry and Arterial Oxygen Saturation Discrepancies.

    Kalra, Andrew / Shou, Benjamin L / Zhao, David / Wilcox, Christopher / Keller, Steven P / Kim, Bo Soo / Whitman, Glenn J R / Cho, Sung-Min

    The Annals of thoracic surgery

    2023  

    Abstract: Background: Cannulation strategy, vasopressors, and hemolysis are important physiological factors that influence hemodynamics in extracorporeal membrane oxygenation (ECMO). We hypothesized these factors influence the discrepancy between oxygen ... ...

    Abstract Background: Cannulation strategy, vasopressors, and hemolysis are important physiological factors that influence hemodynamics in extracorporeal membrane oxygenation (ECMO). We hypothesized these factors influence the discrepancy between oxygen saturation measured by pulse oximetry (Spo
    Methods: We retrospectively analyzed adults (aged ≥18 years) on venoarterial or venovenous ECMO at a tertiary academic ECMO center. Spo
    Results: Of 139 venoarterial-ECMO and 88 venovenous-ECMO patients, we examined 20,053 Spo
    Conclusions: Venovenous-ECMO patients are at higher risk for occult hypoxemia compared with venoarterial-ECMO. A higher vasopressor requirement and different cannulation strategies (central venoarterial-ECMO; single-lumen venovenous-ECMO) were significant factors for clinically significant Spo
    Language English
    Publishing date 2023-09-23
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2023.09.019
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    Zs.A 252: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  10. Article ; Online: Association between influenza vaccination and hospitalisation or all-cause mortality in people with COVID-19: a retrospective cohort study.

    Wilcox, Christopher R / Islam, Nazrul / Dambha-Miller, Hajira

    BMJ open respiratory research

    2020  Volume 8, Issue 1

    Abstract: Introduction: Recent evidence suggests that influenza vaccination may offer protection against COVID-19 severity. Our aim was to quantify the association between influenza vaccination status and risk of hospitalisation or all-cause mortality in people ... ...

    Abstract Introduction: Recent evidence suggests that influenza vaccination may offer protection against COVID-19 severity. Our aim was to quantify the association between influenza vaccination status and risk of hospitalisation or all-cause mortality in people diagnosed with COVID-19.
    Methods: A retrospective cohort study using routinely collected health records from patients registered to a General Practitioner (GP) practice in South West England within the Electronic Care and Health Information Analytics database. The cohort included 6921 people with COVID-19 during the first wave of the pandemic (1 January-31 July 2020). Data on influenza vaccination, hospitalisation and all-cause mortality were ascertained through linked clinical and demographic records. We applied propensity score methods (stabilised inverse probability of treatment weight) to quantify the association between influenza vaccination status and COVID-19 outcomes (hospitalisation or all-cause mortality).
    Results: 2613 (38%) participants received an influenza vaccination between 1 January 2019 and COVID-19 diagnosis. Receipt of influenza vaccination was associated with a significantly lower odds of hospitalisation or all-cause mortality (adjusted OR: 0.85, 95% CI 0.75 to 0.97, p=0.02), and 24% reduced odds of all-cause mortality (adjusted OR: 0.76, 95% CI 0.64 to 0.90).
    Discussion: Influenza vaccination was associated with a 15%-24% lower odds of severe COVID-19 outcomes. The current UK influenza vaccination programme needs urgent expansion as an integral component of the ongoing response plans to the COVID-19 pandemic.
    MeSH term(s) COVID-19/mortality ; Cause of Death ; Cohort Studies ; England ; Hospitalization/statistics & numerical data ; Humans ; Influenza Vaccines/administration & dosage ; Influenza, Human/mortality ; Influenza, Human/prevention & control ; Odds Ratio ; Probability ; Propensity Score ; Retrospective Studies
    Chemical Substances Influenza Vaccines
    Language English
    Publishing date 2020-12-09
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2736454-9
    ISSN 2052-4439 ; 2052-4439
    ISSN (online) 2052-4439
    ISSN 2052-4439
    DOI 10.1136/bmjresp-2020-000857
    Database MEDical Literature Analysis and Retrieval System OnLINE

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