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Article ; Online: Establishing RTS,S/AS01 as a benchmark for comparison to next-generation malaria vaccines in a mouse model.

Locke, Emily / Flores-Garcia, Yevel / Mayer, Bryan T / MacGill, Randall S / Borate, Bhavesh / Salgado-Jimenez, Berenice / Gerber, Monica W / Mathis-Torres, Shamika / Shapiro, Sarah / King, C Richter / Zavala, Fidel

NPJ vaccines

2024 Volume 9, Issue 1, Page(s) 29

Abstract: ... vaccines targeting the circumsporozoite protein (CSP). To improve upon the malaria vaccine, RTS,S/AS01 ... against this benchmark. We focus on RTS,S/AS01-induced antibody responses and functional activity ... doses of RTS,S/AS01 were given intramuscularly at 3-week intervals, with challenge 2-weeks after ...

Abstract	New strategies are needed to reduce the incidence of malaria, and promising approaches include vaccines targeting the circumsporozoite protein (CSP). To improve upon the malaria vaccine, RTS,S/AS01, it is essential to standardize preclinical assays to measure the potency of next-generation vaccines against this benchmark. We focus on RTS,S/AS01-induced antibody responses and functional activity in conjunction with robust statistical analyses. Transgenic Plasmodium berghei sporozoites containing full-length P. falciparum CSP (tgPb-PfCSP) allow two assessments of efficacy: quantitative reduction in liver infection following intravenous challenge, and sterile protection from mosquito bite challenge. Two or three doses of RTS,S/AS01 were given intramuscularly at 3-week intervals, with challenge 2-weeks after the last vaccination. Minimal inter- and intra-assay variability indicates the reproducibility of the methods. Importantly, the range of this model is suitable for screening more potent vaccines. Levels of induced anti-CSP antibody 2A10 equivalency were also associated with activity: 105 μg/mL (95% CI: 68.8, 141) reduced liver infection by 50%, whereas 285 μg/mL (95% CI: 166, 404) is required for 50% sterile protection from mosquito bite challenge. Additionally, the liver burden model was able to differentiate between protected and non-protected human plasma samples from a controlled human malaria infection study, supporting these models' relevance and predictive capability. Comparison in animal models of CSP-based vaccine candidates to RTS,S/AS01 is now possible under well controlled conditions. Assessment of the quality of induced antibodies, likely a determinant of durability of protection in humans, should be possible using these methods.
Language	English
Publishing date	2024-02-10
Publishing country	England
Document type	Journal Article
ISSN	2059-0105
ISSN (online)	2059-0105
DOI	10.1038/s41541-024-00819-x
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Measurement of the Centrality Dependence of the Dijet Yield in p+Pb Collisions at sqrt[s_{NN}]=8.16 TeV with the ATLAS Detector.

Aad, G / Abbott, B / Abeling, K / Abicht, N J / Abidi, S H / Aboulhorma, A / Abramowicz, H / Abreu, H / Abulaiti, Y / Acharya, B S / Adam Bourdarios, C / Adamczyk, L / Addepalli, S V / Addison, M J / Adelman, J / Adiguzel, A / Adye, T / Affolder, A A / Afik, Y /

Agaras, M N / Agarwala, J / Aggarwal, A / Agheorghiesei, C / Ahmad, A / Ahmadov, F / Ahmed, W S / Ahuja, S / Ai, X / Aielli, G / Aikot, A / Ait Tamlihat, M / Aitbenchikh, B / Aizenberg, I / Akbiyik, M / Åkesson, T P A / Akimov, A V / Akiyama, D / Akolkar, N N / Aktas, S / Al Khoury, K / Alberghi, G L / Albert, J / Albicocco, P / Albouy, G L / Alderweireldt, S / Alegria, Z L / Aleksa, M / Aleksandrov, I N / Alexa, C / Alexopoulos, T / Alfonsi, F / Algren, M / Alhroob, M / Ali, B / Ali, H M J / Ali, S / Alibocus, S W / Aliev, M / Alimonti, G / Alkakhi, W / Allaire, C / Allbrooke, B M M / Allen, J F / Allendes Flores, C A / Allport, P P / Aloisio, A / Alonso, F / Alpigiani, C / Alvarez Estevez, M / Alvarez Fernandez, A / Alves Cardoso, M / Alviggi, M G / Aly, M / Amaral Coutinho, Y / Ambler, A / Amelung, C / Amerl, M / Ames, C G / Amidei, D / Amor Dos Santos, S P / Amos, K R / Ananiev, V / Anastopoulos, C / Andeen, T / Anders, J K / Andrean, S Y / Andreazza, A / Angelidakis, S / Angerami, A / Anisenkov, A V / Annovi, A / Antel, C / Anthony, M T / Antipov, E / Antonelli, M / Anulli, F / Aoki, M / Aoki, T / Aparisi Pozo, J A / Aparo, M A / Aperio Bella, L / Appelt, C / Apyan, A / Aranzabal, N / Arbiol Val, S J / Arcangeletti, C / Arce, A T H / Arena, E / Arguin, J-F / Argyropoulos, S / Arling, J-H / Arnaez, O / Arnold, H / Artoni, G / Asada, H / Asai, K / Asai, S / Asbah, N A / Assahsah, J / Assamagan, K / Astalos, R / Atashi, S / Atkin, R J / Atkinson, M / Atmani, H / Atmasiddha, P A / Augsten, K / Auricchio, S / Auriol, A D / Austrup, V A / Avolio, G / Axiotis, K / Azuelos, G / Babal, D / Bachacou, H / Bachas, K / Bachiu, A / Backman, F / Badea, A / Baer, T M / Bagnaia, P / Bahmani, M / Bahner, D / Bailey, A J / Bailey, V R / Baines, J T / Baines, L / Baker, O K / Bakos, E / Bakshi Gupta, D / Balakrishnan, V / Balasubramanian, R / Baldin, E M / Balek, P / Ballabene, E / Balli, F / Baltes, L M / Balunas, W K / Balz, J / Banas, E / Bandieramonte, M / Bandyopadhyay, A / Bansal, S / Barak, L / Barakat, M / Barberio, E L / Barberis, D / Barbero, M / Barel, M Z / Barends, K N / Barillari, T / Barisits, M-S / Barklow, T / Baron, P / Baron Moreno, D A / Baroncelli, A / Barone, G / Barr, A J / Barr, J D / Barranco Navarro, L / Barreiro, F / Barreiro Guimarães da Costa, J / Barron, U / Barros Teixeira, M G / Barsov, S / Bartels, F / Bartoldus, R / Barton, A E / Bartos, P / Basan, A / Baselga, M / Bassalat, A / Basso, M J / Basson, C R / Bates, R L / Batlamous, S / Batley, J R / Batool, B / Battaglia, M / Battulga, D / Bauce, M / Bauer, M / Bauer, P / Bazzano Hurrell, L T / Beacham, J B / Beau, T / Beaucamp, J Y / Beauchemin, P H / Becherer, F / Bechtle, P / Beck, H P / Becker, K / Beddall, A J / Bednyakov, V A / Bee, C P / Beemster, L J / Beermann, T A / Begalli, M / Begel, M / Behera, A / Behr, J K / Beirer, J F / Beisiegel, F / Belfkir, M / Bella, G / Bellagamba, L / Bellerive, A / Bellos, P / Beloborodov, K / Benchekroun, D / Bendebba, F / Benhammou, Y / Benoit, M / Bensinger, J R / Bentvelsen, S / Beresford, L / Beretta, M / Bergeaas Kuutmann, E / Berger, N / Bergmann, B / Beringer, J / Bernardi, G / Bernius, C / Bernlochner, F U / Bernon, F / Berrocal Guardia, A / Berry, T / Berta, P / Berthold, A / Bertram, I A / Bethke, S / Betti, A / Bevan, A J / Bhalla, N K / Bhamjee, M / Bhatta, S / Bhattacharya, D S / Bhattarai, P / Bhopatkar, V S / Bi, R / Bianchi, R M / Bianco, G / Biebel, O / Bielski, R / Biglietti, M / Bindi, M / Bingul, A / Bini, C / Biondini, A / Birch-Sykes, C J / Bird, G A / Birman, M / Biros, M / Biryukov, S / Bisanz, T / Bisceglie, E / Biswal, J P / Biswas, D / Bitadze, A / Bjørke, K / Bloch, I / Blue, A / Blumenschein, U / Blumenthal, J / Bobbink, G J / Bobrovnikov, V S / Boehler, M / Boehm, B / Bogavac, D / Bogdanchikov, A G / Bohm, C / Boisvert, V / Bokan, P / Bold, T / Bomben, M / Bona, M / Boonekamp, M / Booth, C D / Borbély, A G / Bordulev, I S / Borecka-Bielska, H M / Borissov, G / Bortoletto, D / Boscherini, D / Bosman, M / Bossio Sola, J D / Bouaouda, K / Bouchhar, N / Boudreau, J / Bouhova-Thacker, E V / Boumediene, D / Bouquet, R / Boveia, A / Boyd, J / Boye, D / Boyko, I R / Bracinik, J / Brahimi, N / Brandt, G / Brandt, O / Braren, F / Brau, B / Brau, J E / Brener, R / Brenner, L / Brenner, R / Bressler, S / Britton, D / Britzger, D / Brock, I / Brooijmans, G / Brooks, W K / Brost, E / Brown, L M / Bruce, L E / Bruckler, T L / Bruckman de Renstrom, P A / Brüers, B / Bruni, A / Bruni, G / Bruschi, M / Bruscino, N / Buanes, T / Buat, Q / Buchin, D / Buckley, A G / Bulekov, O / Bullard, B A / Burdin, S / Burgard, C D / Burger, A M / Burghgrave, B / Burlayenko, O / Burr, J T P / Burton, C D / Burzynski, J C / Busch, E L / Büscher, V / Bussey, P J / Butler, J M / Buttar, C M / Butterworth, J M / Buttinger, W / Buxo Vazquez, C J / Buzykaev, A R / Cabrera Urbán, S / Cadamuro, L / Caforio, D / Cai, H / Cai, Y / Cairo, V M M / Cakir, O / Calace, N / Calafiura, P / Calderini, G / Calfayan, P / Callea, G / Caloba, L P / Calvet, D / Calvet, S / Calvet, T P / Calvetti, M / Camacho Toro, R / Camarda, S / Camarero Munoz, D / Camarri, P / Camerlingo, M T / Cameron, D / Camincher, C / Campanelli, M / Camplani, A / Canale, V / Canesse, A / Cantero, J / Cao, Y / Capocasa, F / Capua, M / Carbone, A / Cardarelli, R / Cardenas, J C J / Cardillo, F / Carducci, G / Carli, T / Carlino, G / Carlotto, J I / Carlson, B T / Carlson, E M / Carminati, L / Carnelli, A / Carnesale, M / Caron, S / Carquin, E / Carrá, S / Carratta, G / Carrio Argos, F / Carter, J W S / Carter, T M / Casado, M P / Caspar, M / Castillo, F L / Castillo Garcia, L / Castillo Gimenez, V / Castro, N F / Catinaccio, A / Catmore, J R / Cavaliere, V / Cavalli, N / Cavasinni, V / Cekmecelioglu, Y C / Celebi, E / Celli, F / Centonze, M S / Cepaitis, V / Cerny, K / Cerqueira, A S / Cerri, A / Cerrito, L / Cerutti, F / Cervato, B / Cervelli, A / Cesarini, G / Cetin, S A / Chakraborty, D / Chan, J / Chan, W Y / Chapman, J D / Chapon, E / Chargeishvili, B / Charlton, D G / Chatterjee, M / Chauhan, C / Chekanov, S / Chekulaev, S V / Chelkov, G A / Chen, A / Chen, B / Chen, H / Chen, J / Chen, M / Chen, S / Chen, S J / Chen, X / Chen, Y / Cheng, C L / Cheng, H C / Cheong, S / Cheplakov, A / Cheremushkina, E / Cherepanova, E / Cherkaoui El Moursli, R / Cheu, E / Cheung, K / Chevalier, L / Chiarella, V / Chiarelli, G / Chiedde, N / Chiodini, G / Chisholm, A S / Chitan, A / Chitishvili, M / Chizhov, M V / Choi, K / Chomont, A R / Chou, Y / Chow, E Y S / Chowdhury, T / Chu, K L / Chu, M C / Chu, X / Chudoba, J / Chwastowski, J J / Cieri, D / Ciesla, K M / Cindro, V / Ciocio, A / Cirotto, F / Citron, Z H / Citterio, M / Ciubotaru, D A / Clark, A / Clark, P J / Clarry, C / Clavijo Columbie, J M / Clawson, S E / Clement, C / Clercx, J / Coadou, Y / Cobal, M / Coccaro, A / Barrue, R F Coelho / Coelho Lopes De Sa, R / Coelli, S / Coimbra, A E C / Cole, B / Collot, J / Conde Muiño, P / Connell, M P / Connell, S H / Connelly, I A / Conroy, E I / Conventi, F / Cooke, H G / Cooper-Sarkar, A M / Cordeiro Oudot Choi, A / Corpe, L D / Corradi, M / Corriveau, F / Cortes-Gonzalez, A / Costa, M J / Costanza, F / Costanzo, D / Cote, B M / Cowan, G / Cranmer, K / Cremonini, D / Crépé-Renaudin, S / Crescioli, F / Cristinziani, M / Cristoforetti, M / Croft, V / Crosby, J E / Crosetti, G / Cueto, A / Cuhadar Donszelmann, T / Cui, H / Cui, Z / Cunningham, W R / Curcio, F / Czodrowski, P / Czurylo, M M / De Sousa, M J Da Cunha Sargedas / Da Fonseca Pinto, J V / Da Via, C / Dabrowski, W / Dado, T / Dahbi, S / Dai, T / Dal Santo, D / Dallapiccola, C / Dam, M / D'amen, G / D'Amico, V / Damp, J / Dandoy, J R / Daneri, M F / Danninger, M / Dao, V / Darbo, G / Darmora, S / Das, S J / D'Auria, S / David, C / Davidek, T / Davis-Purcell, B / Dawson, I / Day-Hall, H A / De, K / De Asmundis, R / De Biase, N / De Castro, S / De Groot, N / de Jong, P / De la Torre, H / De Maria, A / De Salvo, A / De Sanctis, U / De Santis, F 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Santos Fernandes, N / Dougan, P / Dova, M T / Doyle, A T / Draguet, M A / Dreyer, E / Drivas-Koulouris, I / Drnevich, M / Drobac, A S / Drozdova, M / Du, D / du Pree, T A / Dubinin, F / Dubovsky, M / Duchovni, E / Duckeck, G / Ducu, O A / Duda, D / Dudarev, A / Duden, E R / D'uffizi, M / Duflot, L / Dührssen, M / Dülsen, C / Dumitriu, A E / Dunford, M / Dungs, S / Dunne, K / Duperrin, A / Yildiz, H Duran / Düren, M / Durglishvili, A / Dwyer, B L / Dyckes, G I / Dyndal, M / Dziedzic, B S / Earnshaw, Z O / Eberwein, G H / Eckerova, B / Eggebrecht, S / Purcino De Souza, E Egidio / Ehrke, L F / Eigen, G / Einsweiler, K / Ekelof, T / Ekman, P A / El Farkh, S / El Ghazali, Y / El Jarrari, H / El Moussaouy, A / Ellajosyula, V / Ellert, M / Ellinghaus, F / Ellis, N / Elmsheuser, J / Elsing, M / Emeliyanov, D / Enari, Y / Ene, I / Epari, S / Erdmann, J / Erland, P A / Errenst, M / Escalier, M / Escobar, C / Etzion, E / Evans, G / Evans, H / Evans, L S / Evans, M O / Ezhilov, A / Ezzarqtouni, S / Fabbri, F / Fabbri, L / Facini, G / Fadeyev, V / Fakhrutdinov, R M / Fakoudis, D / Falciano, S / Falda Ulhoa Coelho, L F / Falke, P J / Faltova, J / Fan, C / Fan, Y / Fang, Y / Fanti, M / Faraj, M / Farazpay, Z / Farbin, A / Farilla, A / Farooque, T / Farrington, S M / Fassi, F / Fassouliotis, D / Faucci Giannelli, M / Fawcett, W J / Fayard, L / Federic, P / Federicova, P / Fedin, O L / Fedotov, G / Feickert, M / Feligioni, L / Fellers, D E / Feng, C / Feng, M / Feng, Z / Fenton, M J / Fenyuk, A B / Ferencz, L / Ferguson, R A M / Fernandez Luengo, S I / Fernandez Martinez, P / Fernoux, M J V / Ferrando, J / Ferrari, A / Ferrari, P / Ferrari, R / Ferrere, D / Ferretti, C / Fiedler, F / Fiedler, P / Filipčič, A / Filmer, E K / Filthaut, F / Fiolhais, M C N / Fiorini, L / Fisher, W C / Fitschen, T / Fitzhugh, P M / Fleck, I / Fleischmann, P / Flick, T / Flores, M / Flores Castillo, L R / Flores Sanz De Acedo, L / Follega, F M / Fomin, N / Foo, J H / Forland, B C / Formica, A / Forti, A C / Fortin, E / Fortman, A W / Foti, M G / Fountas, L / Fournier, D / Fox, H / Francavilla, P / Francescato, S / Franchellucci, S / Franchini, M / Franchino, S / Francis, D / Franco, L / Franco Lima, V / Franconi, L / Franklin, M / Frattari, G / Freegard, A C / Freund, W S / Frid, Y Y / Friend, J / Fritzsche, N / Froch, A / Froidevaux, D / Frost, J A / Fu, Y / Fuenzalida Garrido, S / Fujimoto, M / Fung, K Y / De Simas Filho, E Furtado / Furukawa, M / Fuster, J / Gabrielli, A / Gadow, P / Gagliardi, G / Gagnon, L G / Gallas, E J / Gallop, B J / Gan, K K / Ganguly, S / Gao, Y / Garay Walls, F M / Garcia, B / García, C / Garcia Alonso, A / Garcia Caffaro, A G / García Navarro, J E / Garcia-Sciveres, M / Gardner, G L / Gardner, R W / Garelli, N / Garg, D / Garg, R B / Gargan, J M / Garner, C A / Garvey, C M / Gaspar, P / Gassmann, V K / Gaudio, G / Gautam, V / Gauzzi, P / Gavrilenko, I L / Gavrilyuk, A / Gay, C / Gaycken, G / Gazis, E N / Geanta, A A / Gee, C M / Gekow, A / Gemme, C / 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Zormpa, O / Zou, W / Zwalinski, L

Physical review letters

2024 Volume 132, Issue 10, Page(s) 102301

Abstract: ... data collected at sqrt[s_{NN}]=8.16 TeV in 2016. The event centrality, which reflects the p+Pb impact parameter ...

Abstract	ATLAS measured the centrality dependence of the dijet yield using 165 nb^{-1} of p+Pb data collected at sqrt[s_{NN}]=8.16 TeV in 2016. The event centrality, which reflects the p+Pb impact parameter, is characterized by the total transverse energy registered in the Pb-going side of the forward calorimeter. The central-to-peripheral ratio of the scaled dijet yields, R_{CP}, is evaluated, and the results are presented as a function of variables that reflect the kinematics of the initial hard parton scattering process. The R_{CP} shows a scaling with the Bjorken x of the parton originating from the proton, x_{p}, while no such trend is observed as a function of x_{Pb}. This analysis provides unique input to understanding the role of small proton spatial configurations in p+Pb collisions by covering parton momentum fractions from the valence region down to x_{p}∼10^{-3} and x_{Pb}∼4×10^{-4}.
Language	English
Publishing date	2024-03-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.132.102301
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Observation of WZγ Production in pp Collisions at sqrt[s]=13 TeV with the ATLAS Detector.

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S / Cohen, H / Coimbra, A E C / Cole, B / Collot, J / Conde Muiño, P / Connell, M P / Connell, S H / Connelly, I A / Conroy, E I / Conventi, F / Cooke, H G / Cooper-Sarkar, A M / Cordeiro Oudot Choi, A / Cormier, F / Corpe, L D / Corradi, M / Corriveau, F / Cortes-Gonzalez, A / Costa, M J / Costanza, F / Costanzo, D / Cote, B M / Cowan, G / Cranmer, K / Cremonini, D / Crépé-Renaudin, S / Crescioli, F / Cristinziani, M / Cristoforetti, M / Croft, V / Crosby, J E / Crosetti, G / Cueto, A / Cuhadar Donszelmann, T / Cui, H / Cui, Z / Cunningham, W R / Curcio, F / Czodrowski, P / Czurylo, M M / De Sousa, M J Da Cunha Sargedas / Da Fonseca Pinto, J V / Da Via, C / Dabrowski, W / Dado, T / Dahbi, S / Dai, T / Dallapiccola, C / Dam, M / D'amen, G / D'Amico, V / Damp, J / Dandoy, J R / Daneri, M F / Danninger, M / Dao, V / Darbo, G / Darmora, S / Das, S J / D'Auria, S / David, C / Davidek, T / Davis-Purcell, B / Dawson, I / Day-Hall, H A / De, K / De Asmundis, R / De Biase, N / De Castro, S / De Groot, N / de Jong, P / De la Torre, H / De Maria, A / De Salvo, A / De Sanctis, U / De Santo, A / De Vivie De Regie, J B / Dedovich, D V / Degens, J / Deiana, A M / Del Corso, F / Del Peso, J / Del Rio, F / Deliot, F / Delitzsch, C M / Della Pietra, M / Della Volpe, D / Dell'Acqua, A / Dell'Asta, L / Delmastro, M / Delsart, P A / Demers, S / Demichev, M / Denisov, S P / D'Eramo, L / Derendarz, D / Derue, F / Dervan, P / Desch, K / Deutsch, C / Di Bello, F A / Di Ciaccio, A / Di Ciaccio, L / Di Domenico, A / Di Donato, C / Di Girolamo, A / Di Gregorio, G / Di Luca, A / Di Micco, B / Di Nardo, R / Diaconu, C / Diamantopoulou, M / Dias, F A / Vale, T Dias Do / Diaz, M A / Diaz Capriles, F G / Didenko, M / Diehl, E B / Diehl, L / Díez Cornell, S / Diez Pardos, C / Dimitriadi, C / Dimitrievska, A / Dingfelder, J / Dinu, I-M / Dittmeier, S J / Dittus, F / Djama, F / Djobava, T / Djuvsland, J I / Doglioni, C / Dolejsi, J / Dolezal, Z / Donadelli, M / Dong, B / Donini, J / D'Onofrio, A / D'Onofrio, M / Dopke, J / Doria, A / Dos Santos Fernandes, N / Dova, M T / Doyle, A T / Draguet, M A / Dreyer, E / Drivas-Koulouris, I / Drobac, A S / Drozdova, M / Du, D / du Pree, T A / Dubinin, F / Dubovsky, M / Duchovni, E / Duckeck, G / Ducu, O A / Duda, D / Dudarev, A / Duden, E R / D'uffizi, M / Duflot, L / Dührssen, M / Dülsen, C / Dumitriu, A E / Dunford, M / Dungs, S / Dunne, K / Duperrin, A / Yildiz, H Duran / Düren, M / Durglishvili, A / Dwyer, B L / Dyckes, G I / Dyndal, M / Dysch, S / Dziedzic, B S / Earnshaw, Z O / Eberwein, G H / Eckerova, B / Eggebrecht, S / Eggleston, M G / Purcino De Souza, E Egidio / Ehrke, L F / Eigen, G / Einsweiler, K / Ekelof, T / Ekman, P A / El Farkh, S / El Ghazali, Y / El Jarrari, H / El Moussaouy, A / Ellajosyula, V / Ellert, M / Ellinghaus, F / Elliot, A A / Ellis, N / Elmsheuser, J / Elsing, M / Emeliyanov, D / Enari, Y / Ene, I / Epari, S / Erdmann, J / Erland, P A / Errenst, M / Escalier, M / Escobar, C / Etzion, E / Evans, G / Evans, H / Evans, L S / Evans, M O / Ezhilov, A / Ezzarqtouni, S / Fabbri, F / Fabbri, L / Facini, G / Fadeyev, V / Fakhrutdinov, R M / Falciano, S / Falda Ulhoa Coelho, L F / Falke, P J / Faltova, J / Fan, C / Fan, Y / Fang, Y / Fanti, M / Faraj, M / Farazpay, Z / Farbin, A / Farilla, A / Farooque, T / Farrington, S M / Fassi, F / Fassouliotis, D / Faucci Giannelli, M / Fawcett, W J / Fayard, L / Federic, P / Federicova, P / Fedin, O L / Fedotov, G / Feickert, M / Feligioni, L / Fellers, D E / Feng, C / Feng, M / Feng, Z / Fenton, M J / Fenyuk, A B / Ferencz, L / Ferguson, R A M / Fernandez Luengo, S I / Fernoux, M J V / Ferrando, J / Ferrari, A / Ferrari, P / Ferrari, R / Ferrere, D / Ferretti, C / Fiedler, F / Filipčič, A / Filmer, E K / Filthaut, F / Fiolhais, M C N / Fiorini, L / Fisher, W C / Fitschen, T / Fitzhugh, P M / Fleck, I / Fleischmann, P / Flick, T / Flores, L / Flores, M / Flores Castillo, L R / Flores Sanz De Acedo, L / Follega, F M / Fomin, N / Foo, J H / Forland, B C / Formica, A / Forti, A C / Fortin, E / Fortman, A W / Foti, M G / Fountas, L / Fournier, D / Fox, H / Francavilla, P / Francescato, S / Franchellucci, S / Franchini, M / Franchino, S / Francis, D / Franco, L / Franconi, L / Franklin, M / Frattari, G / Freegard, A C / Freund, W S / Frid, Y Y / Fritzsche, N / Froch, A / Froidevaux, D / Frost, J A / Fu, Y / Fujimoto, M / Fullana Torregrosa, E / Fung, K Y / De Simas Filho, E Furtado / Furukawa, M / Fuster, J / Gabrielli, A / Gadow, P / Gagliardi, G / Gagnon, L G / Gallas, E J / Gallop, B J / Gan, K K / Ganguly, S / Gao, J / Gao, Y / Garay Walls, F M / Garcia, B / García, C / Garcia Alonso, A / Garcia Caffaro, A G / García Navarro, J E / Garcia-Sciveres, M / Gardner, G L / Gardner, R W / Garelli, N / Garg, D / Garg, R B / Gargan, J M / Garner, C A / Gasiorowski, S J / Gaspar, P / Gaudio, G / Gautam, V / Gauzzi, P / Gavrilenko, I L / Gavrilyuk, A / Gay, C / Gaycken, G / Gazis, E N / Geanta, A A / Gee, C M / Gemme, C / Genest, M H / Gentile, S / George, S / George, W F / Geralis, T / Gessinger-Befurt, P / Geyik, M E / Ghneimat, M / Ghorbanian, K / Ghosal, A / Ghosh, A / Giacobbe, B / Giagu, S / Giannetti, P / Giannini, A / Gibson, S M / Gignac, M / Gil, D T / Gilbert, A K / Gilbert, B J / Gillberg, D / Gilles, G / Gillwald, N E K / Ginabat, L / Gingrich, D M / Giordani, M P / Giraud, P F / Giugliarelli, G / Giugni, D / Giuli, F / Gkialas, I / Gladilin, L K / Glasman, C / Gledhill, G R / Glemža, G / Glisic, M / Gnesi, I / Go, Y / Goblirsch-Kolb, M / Gocke, B / Godin, D / Gokturk, B / Goldfarb, S / Golling, T / Gololo, M G D / Golubkov, D / Gombas, J P / Gomes, A / Gomes Da Silva, G / Gomez Delegido, A J / Gonçalo, R / Gonella, G / Gonella, L / Gongadze, A / Gonnella, F / Gonski, J L / González Andana, R Y / González de la Hoz, S / Gonzalez Fernandez, S / Gonzalez Lopez, R / Gonzalez Renteria, C / Gonzalez Suarez, R / Gonzalez-Sevilla, S / Gonzalvo Rodriguez, G R / Goossens, L / Gorbounov, P A / Gorini, B / Gorini, E / Gorišek, A / Gosart, T C / Goshaw, A T / Gostkin, M I / Goswami, S / Gottardo, C A / Gouighri, M / Goumarre, V / Goussiou, A G / Govender, N / Grabowska-Bold, I / Graham, K / Gramstad, E / Grancagnolo, S / Grandi, M / Gravila, P M / Gravili, F G / Gray, H M / Greco, M / Grefe, C / Gregor, I M / Grenier, P / Grieco, C / Grillo, A A / Grimm, K / Grinstein, S / Grivaz, J-F / Gross, E / Grosse-Knetter, J / Grud, C / Grundy, J C / Guan, L / Guan, W / Gubbels, C / Guerrero Rojas, J G R / Guerrieri, G / Guescini, F / Gugel, R / Guhit, J A M / Guida, A / Guillemin, T / Guilloton, E / Guindon, S / Guo, F / Guo, J / Guo, L / Guo, Y / Gupta, R / Gurbuz, S / Gurdasani, S S / Gustavino, G / Guth, M / Gutierrez, P / Gutierrez Zagazeta, L F / Gutschow, C / Gwenlan, C / Gwilliam, C B / Haaland, E S / Haas, A / Habedank, M / Haber, C / Hadavand, H K / Hadef, A / Hadzic, S / Hahn, J J / Haines, E H / Haleem, M / Haley, J / Hall, J J / Hallewell, G D / Halser, L / Hamano, K / Hamdaoui, H / Hamer, M / Hamity, G N / Hampshire, E J / Han, J / Han, K / Han, L / Han, S / Han, Y F / Hanagaki, K / Hance, M / Hangal, D A / Hanif, H / Hank, M D / Hankache, R / Hansen, J B / Hansen, J D / Hansen, P H / Hara, K / Harada, D / Harenberg, T / Harkusha, S / Harris, M L / Harris, Y T / Harrison, J / Harrison, N M / Harrison, P F / Hartman, N M / Hartmann, N M / Hasegawa, Y / Hasib, A / Haug, S / Hauser, R / Hawkes, C M / Hawkings, R J / Hayashi, Y / Hayashida, S / Hayden, D / Hayes, C / Hayes, R L / Hays, C P / Hays, J M / Hayward, H S / He, F / He, M / He, Y / Heatley, N B / Hedberg, V / Heggelund, A L / Hehir, N D / Heidegger, C / Heidegger, K K / Heidorn, W D / Heilman, J / Heim, S / Heim, T / Heinemann, B / Heinlein, J G / Heinrich, J J / Heinrich, L / Hejbal, J / Helary, L / Held, A / Hellesund, S / Helling, C M / Hellman, S / Henderson, R C W / Henkelmann, L / Henriques Correia, A M / Herde, H / Hernández Jiménez, Y / Herrmann, L M / Herrmann, T / Herten, G / Hertenberger, R / Hervas, L / 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J M / Iuppa, R / Ivina, A / Izen, J M / Izzo, V / Jacka, P / Jackson, P / Jacobs, R M / Jaeger, B P / Jagfeld, C S / Jain, P / Jäkel, G / Jakobs, K / Jakoubek, T / Jamieson, J / Janas, K W / Jaspan, A E / Javurkova, M / Jeanneau, F / Jeanty, L / Jejelava, J / Jenni, P / Jessiman, C E / Jézéquel, S / Jia, C / Jia, J / Jia, X / Jia, Z / Jiang, Y / Jiggins, S / Jimenez Pena, J / Jin, S / Jinaru, A / Jinnouchi, O / Johansson, P / Johns, K A / Johnson, J W / Jones, D M / Jones, E / Jones, P / Jones, R W L / Jones, T J / Joshi, R / Jovicevic, J / Ju, X / Junggeburth, J J / Junkermann, T / Juste Rozas, A / Juzek, M K / Kabana, S / Kaczmarska, A / Kado, M / Kagan, H / Kagan, M / Kahn, A / Kahra, C / Kaji, T / Kajomovitz, E / Kakati, N / Kalaitzidou, I / Kalderon, C W / Kamenshchikov, A / Kanayama, S / Kang, N J / Kar, D / Karava, K / Kareem, M J / Karentzos, E / Karkanias, I / Karkout, O / Karpov, S N / Karpova, Z M / Kartvelishvili, V / Karyukhin, A N / Kasimi, E / Katzy, J / Kaur, S / Kawade, K / Kawale, M P / Kawamoto, T / Kay, E F / Kaya, F I / Kazakos, S / Kazanin, V F / Ke, Y / Keaveney, J M / Keeler, R / Kehris, G V / Keller, J S / Kelly, A S / Kempster, J J / Kennedy, K E / Kennedy, P D / Kepka, O / Kerridge, B P / Kersten, S / Kerševan, B P / Keshri, S / Keszeghova, L / Ketabchi Haghighat, S / Khandoga, M / Khanov, A / Kharlamov, A G / Kharlamova, T / Khoda, E E / Khoo, T J / Khoriauli, G / Khubua, J / Khwaira, Y A R / Kilgallon, A / Kim, D W / Kim, Y K / Kimura, N / Kirchhoff, A / Kirfel, C / Kirfel, F / Kirk, J / Kiryunin, A E / Kitsaki, C / Kivernyk, O / Klassen, M / Klein, C / Klein, L / Klein, M H / Klein, M / Klein, S B / Klein, U / Klimek, P / Klimentov, A / Klioutchnikova, T / Kluit, P / Kluth, S / Kneringer, E / Knight, T M / Knue, A / Kobayashi, R / Koch, S F / Kocian, M / Kodyš, P / Koeck, D M / Koenig, P T / Koffas, T / Kolb, M / Koletsou, I / Komarek, T / Köneke, K / Kong, A X Y / Kono, T / Konstantinidis, N / Konya, B / Kopeliansky, R / Koperny, S / Korcyl, K / Kordas, K / Koren, G / Korn, A / Korn, S / Korolkov, I / Korotkova, N / Kortman, B / Kortner, O / Kortner, S / Kostecka, W H / Kostyukhin, V V / Kotsokechagia, A / Kotwal, A / Koulouris, A / Kourkoumeli-Charalampidi, A / Kourkoumelis, C / Kourlitis, E / Kovanda, O / Kowalewski, R / Kozanecki, W / Kozhin, A S / Kramarenko, V A / Kramberger, G / Kramer, P / Krasny, M W / Krasznahorkay, A / Kraus, J W / Kremer, J A / Kresse, T / Kretzschmar, J / Kreul, K / Krieger, P / Krishnamurthy, S / Krivos, M / Krizka, K / Kroeninger, K / Kroha, H / Kroll, J / Krowpman, K S / Kruchonak, U / Krüger, H / Krumnack, N / Kruse, M C / Krzysiak, J A / Kuchinskaia, O / Kuday, S / Kuehn, S / Kuesters, R / Kuhl, T / Kukhtin, V / Kulchitsky, Y / Kuleshov, S / Kumar, M / Kumari, N / Kupco, A / Kupfer, T / Kupich, A / Kuprash, O / Kurashige, H / Kurchaninov, L L / Kurdysh, O / Kurochkin, Y A / Kurova, A / Kuze, M / Kvam, A K / Kvita, J / Kwan, T / Kyriacou, N G / Laatu, L A O / Lacasta, C / 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C / Li, C-Q / Li, H / Li, K / Li, L / Li, M / Li, Q Y / Li, S / Li, T / Li, X / Li, Z / Liang, Z / Liberatore, M / Liberti, B / Lie, K / Lieber Marin, J / Lien, H / Lin, K / Lindley, R E / Lindon, J H / Linss, A / Lipeles, E / Lipniacka, A / Lister, A / Little, J D / Liu, B / Liu, B X / Liu, D / Liu, J B / Liu, J K K / Liu, K / Liu, M / Liu, M Y / Liu, P / Liu, Q / Liu, X / Liu, Y / Liu, Y L / Liu, Y W / Llorente Merino, J / Lloyd, S L / Lobodzinska, E M / Loch, P / Loffredo, S / Lohse, T / Lohwasser, K / Loiacono, E / Lokajicek, M / Lomas, J D / Long, J D / Longarini, I / Longo, L / Longo, R / Lopez Paz, I / Lopez Solis, A / Lorenz, J / Lorenzo Martinez, N / Lory, A M / Löschcke Centeno, G / Loseva, O / Lou, X / Lounis, A / Love, J / Love, P A / Lu, G / Lu, M / Lu, S / Lu, Y J / Lubatti, H J / Luci, C / Lucio Alves, F L / Lucotte, A / Luehring, F / Luise, I / Lukianchuk, O / Lundberg, O / Lund-Jensen, B / Luongo, N A / Lutz, M S / Lynn, D / Lyons, H / Lysak, R / Lytken, E / 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Physical review letters

2024 Volume 132, Issue 2, Page(s) 21802

Abstract: This Letter reports the observation of WZγ production and a measurement of its cross section using 140.1±1.2 fb^{-1} of proton-proton collision data recorded at a center-of-mass energy of 13 TeV by the ATLAS detector at the Large Hadron Collider. The ... ...

Abstract	This Letter reports the observation of WZγ production and a measurement of its cross section using 140.1±1.2 fb^{-1} of proton-proton collision data recorded at a center-of-mass energy of 13 TeV by the ATLAS detector at the Large Hadron Collider. The WZγ production cross section, with both the W and Z bosons decaying leptonically, pp→WZγ→ℓ^{'}^{±}νℓ^{+}ℓ^{-}γ (ℓ^{(^{'})}=e, μ), is measured in a fiducial phase-space region defined such that the leptons and the photon have high transverse momentum and the photon is isolated. The cross section is found to be 2.01±0.30(stat)±0.16(syst) fb. The corresponding standard model predicted cross section calculated at next-to-leading order in perturbative quantum chromodynamics and at leading order in the electroweak coupling constant is 1.50±0.06 fb. The observed significance of the WZγ signal is 6.3σ, compared with an expected significance of 5.0σ.
Language	English
Publishing date	2024-01-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.132.021802
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Article ; Online: Immunogenicity of the Ad26.COV2.S Vaccine for COVID-19.

Stephenson, Kathryn E / Le Gars, Mathieu / Sadoff, Jerald / de Groot, Anne Marit / Heerwegh, Dirk / Truyers, Carla / Atyeo, Caroline / Loos, Carolin / Chandrashekar, Abishek / McMahan, Katherine / Tostanoski, Lisa H / Yu, Jingyou / Gebre, Makda S / Jacob-Dolan, Catherine / Li, Zhenfeng / Patel, Shivani / Peter, Lauren / Liu, Jinyan / Borducchi, Erica N /

Nkolola, Joseph P / Souza, Morgana / Tan, Chen Sabrina / Zash, Rebecca / Julg, Boris / Nathavitharana, Ruvandhi R / Shapiro, Roger L / Azim, Ahmed Abdul / Alonso, Carolyn D / Jaegle, Kate / Ansel, Jessica L / Kanjilal, Diane G / Guiney, Caitlin J / Bradshaw, Connor / Tyler, Anna / Makoni, Tatenda / Yanosick, Katherine E / Seaman, Michael S / Lauffenburger, Douglas A / Alter, Galit / Struyf, Frank / Douoguih, Macaya / Van Hoof, Johan / Schuitemaker, Hanneke / Barouch, Dan H

JAMA

2021 Volume 325, Issue 15, Page(s) 1535–1544

Abstract: ... of safe and effective vaccines.: Objective: To evaluate the immunogenicity of the Ad26.COV2.S vaccine ... blind, placebo-controlled phase 1 clinical trial of Ad26.COV2.S.: Interventions: Participants were ... viral particles of Ad26.COV2.S vaccine or placebo administered on day 1 and day 57 (5 participants in each group ...

Abstract	Importance: Control of the global COVID-19 pandemic will require the development and deployment of safe and effective vaccines. Objective: To evaluate the immunogenicity of the Ad26.COV2.S vaccine (Janssen/Johnson & Johnson) in humans, including the kinetics, magnitude, and phenotype of SARS-CoV-2 spike-specific humoral and cellular immune responses. Design, setting, and participants: Twenty-five participants were enrolled from July 29, 2020, to August 7, 2020, and the follow-up for this day 71 interim analysis was completed on October 3, 2020; follow-up to assess durability will continue for 2 years. This study was conducted at a single clinical site in Boston, Massachusetts, as part of a randomized, double-blind, placebo-controlled phase 1 clinical trial of Ad26.COV2.S. Interventions: Participants were randomized to receive 1 or 2 intramuscular injections with 5 × 1010 viral particles or 1 × 1011 viral particles of Ad26.COV2.S vaccine or placebo administered on day 1 and day 57 (5 participants in each group). Main outcomes and measures: Humoral immune responses included binding and neutralizing antibody responses at multiple time points following immunization. Cellular immune responses included immunospot-based and intracellular cytokine staining assays to measure T-cell responses. Results: Twenty-five participants were randomized (median age, 42; age range, 22-52; 52% women, 44% male, 4% undifferentiated), and all completed the trial through the day 71 interim end point. Binding and neutralizing antibodies emerged rapidly by day 8 after initial immunization in 90% and 25% of vaccine recipients, respectively. By day 57, binding and neutralizing antibodies were detected in 100% of vaccine recipients after a single immunization. On day 71, the geometric mean titers of spike-specific binding antibodies were 2432 to 5729 and the geometric mean titers of neutralizing antibodies were 242 to 449 in the vaccinated groups. A variety of antibody subclasses, Fc receptor binding properties, and antiviral functions were induced. CD4+ and CD8+ T-cell responses were induced. Conclusion and relevance: In this phase 1 study, a single immunization with Ad26.COV2.S induced rapid binding and neutralization antibody responses as well as cellular immune responses. Two phase 3 clinical trials are currently underway to determine the efficacy of the Ad26.COV2.S vaccine. Trial registration: ClinicalTrials.gov Identifier: NCT04436276.
MeSH term(s)	Adult ; Antibodies, Neutralizing/blood ; Antibodies, Viral/blood ; COVID-19/immunology ; COVID-19/prevention & control ; COVID-19 Vaccines/administration & dosage ; COVID-19 Vaccines/immunology ; Double-Blind Method ; Female ; Humans ; Immunity, Cellular ; Immunity, Humoral ; Immunogenicity, Vaccine ; Male ; Middle Aged ; Vaccine Potency ; Young Adult
Chemical Substances	Antibodies, Neutralizing ; Antibodies, Viral ; COVID-19 Vaccines
Language	English
Publishing date	2021-03-11
Publishing country	United States
Document type	Clinical Trial, Phase I ; Comparative Study ; Journal Article ; Randomized Controlled Trial ; Research Support, N.I.H., Extramural
ZDB-ID	2958-0
ISSN	1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
ISSN (online)	1538-3598
ISSN	0254-9077 ; 0002-9955 ; 0098-7484
DOI	10.1001/jama.2021.3645
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Article ; Online: Notes from the Field: Transmission of Mpox to Nonsexual Close Contacts - Two U.S. Jurisdictions, May 1-July 31, 2022.

Thomas, Ebony S / Madewell, Zachary J / Still, William L / Rowse, Julia / Shapiro, Brandon / Gately, Emily / Shaffner, Julie / Mangla, Anil T / Ricaldi, Jessica N

MMWR. Morbidity and mortality weekly report

2023 Volume 72, Issue 50, Page(s) 1351–1352

MeSH term(s)	Humans ; Mpox (monkeypox)/transmission
Language	English
Publishing date	2023-12-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	412775-4
ISSN	1545-861X ; 0149-2195
ISSN (online)	1545-861X
ISSN	0149-2195
DOI	10.15585/mmwr.mm7250a3
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Article ; Online: Search for New Phenomena in Two-Body Invariant Mass Distributions Using Unsupervised Machine Learning for Anomaly Detection at sqrt[s]=13 TeV with the ATLAS Detector.

Affolder, A A / Afik, Y / Agaras, M N / Agarwala, J / Aggarwal, A / Agheorghiesei, C / Ahmad, A / Ahmadov, F / Ahmed, W S / Ahuja, S / Ai, X / Aielli, G / Aikot, A / Ait Tamlihat, M / Aitbenchikh, B / Aizenberg, I / Akbiyik, M / Åkesson, T P A / Akimov, A V / Akiyama, D / Akolkar, N N / Al Khoury, K / Alberghi, G L / Albert, J / Albicocco, P / Albouy, G L / Alderweireldt, S / Aleksa, M / Aleksandrov, I N / Alexa, C / Alexopoulos, T / Alfonsi, F / Algren, M / Alhroob, M / Ali, B / Ali, H M J / Ali, S / Alibocus, S W / Aliev, M / Alimonti, G / Alkakhi, W / Allaire, C / Allbrooke, B M M / Allen, J F / Allendes Flores, C A / Allport, P P / Aloisio, A / Alonso, F / Alpigiani, C / Alvarez Estevez, M / Alvarez Fernandez, A / Alves Cardoso, M / Alviggi, M G / Aly, M / Amaral Coutinho, Y / Ambler, A / Amelung, C / Amerl, M / Ames, C G / Amidei, D / Amor Dos Santos, S P / Amos, K R / Ananiev, V / Anastopoulos, C / Andeen, T / Anders, J K / Andrean, S Y / Andreazza, A / Angelidakis, S / Angerami, A / Anisenkov, A V / Annovi, A / Antel, C / Anthony, M T / Antipov, E / Antonelli, M / Anulli, F / Aoki, M / Aoki, T / Aparisi Pozo, J A / Aparo, M A / Aperio Bella, L / Appelt, C / Apyan, A / Aranzabal, N / Arcangeletti, C / Arce, A T H / Arena, E / Arguin, J-F / Argyropoulos, S / Arling, J-H / Arnaez, O / Arnold, H / Artoni, G / Asada, H / Asai, K / Asai, S / Asbah, N A / Assahsah, J / Assamagan, K / Astalos, R / Atashi, S / Atkin, R J / Atkinson, M / Atmani, H / Atmasiddha, P A / Augsten, K / Auricchio, S / Auriol, A D / Austrup, V A / Avolio, G / Axiotis, K / Azuelos, G / Babal, D / Bachacou, H / Bachas, K / Bachiu, A / Backman, F / Badea, A / Bagnaia, P / Bahmani, M / Bailey, A J / Bailey, V R / Baines, J T / Baines, L / Bakalis, C / Baker, O K / Bakos, E / Bakshi Gupta, D / Balakrishnan, V / Balasubramanian, R / Baldin, E M / Balek, P / Ballabene, E / Balli, F / Baltes, L M / Balunas, W K / Balz, J / Banas, E / Bandieramonte, M / Bandyopadhyay, A / Bansal, S / Barak, L / Barakat, M / Barberio, E L / Barberis, D / Barbero, M / Barends, K N / Barillari, T / Barisits, M-S / Barklow, T / Baron, P / Baron Moreno, D A / Baroncelli, A / Barone, G / Barr, A J / Barr, J D / Barranco Navarro, L / Barreiro, F / Barreiro Guimarães da Costa, J / Barron, U / Barros Teixeira, M G / Barsov, S / Bartels, F / Bartoldus, R / Barton, A E / Bartos, P / Basan, A / Baselga, M / Bassalat, A / Basso, M J / Basson, C R / Bates, R L / Batlamous, S / Batley, J R / Batool, B / Battaglia, M / Battulga, D / Bauce, M / Bauer, M / Bauer, P / Bazzano Hurrell, L T / Beacham, J B / Beau, T / Beauchemin, P H / Becherer, F / Bechtle, P / Beck, H P / Becker, K / Beddall, A J / Bednyakov, V A / Bee, C P / Beemster, L J / Beermann, T A / Begalli, M / Begel, M / Behera, A / Behr, J K / Beirer, J F / Beisiegel, F / Belfkir, M / Bella, G / Bellagamba, L / Bellerive, A / Bellos, P / Beloborodov, K / Belyaev, N L / Benchekroun, D / Bendebba, F / Benhammou, Y / Benoit, M / Bensinger, J R / Bentvelsen, S / Beresford, L / Beretta, M / Bergeaas Kuutmann, E / Berger, N / Bergmann, B / Beringer, J / Bernardi, G / Bernius, C / Bernlochner, F U / Bernon, F / Berry, T / Berta, P / Berthold, A / Bertram, I A / Bethke, S / Betti, A / Bevan, A J / Bhamjee, M / Bhatta, S / Bhattacharya, D S / Bhattarai, P / Bhopatkar, V S / Bi, R / Bianchi, R M / Bianco, G / Biebel, O / Bielski, R / Biglietti, M / Billoud, T R V / Bindi, M / Bingul, A / Bini, C / Biondini, A / Birch-Sykes, C J / Bird, G A / Birman, M / Biros, M / Biryukov, S / Bisanz, T / Bisceglie, E / Biswal, J P / Biswas, D / Bitadze, A / Bjørke, K / Bloch, I / Blocker, C / Blue, A / Blumenschein, U / Blumenthal, J / Bobbink, G J / Bobrovnikov, V S / Boehler, M / Boehm, B / Bogavac, D / Bogdanchikov, A G / Bohm, C / Boisvert, V / Bokan, P / Bold, T / Bomben, M / Bona, M / Boonekamp, M / Booth, C D / Borbély, A G / Bordulev, I S / Borecka-Bielska, H M / Borgna, L S / Borissov, G / Bortoletto, D / Boscherini, D / Bosman, M / Bossio Sola, J D / Bouaouda, K / Bouchhar, N / Boudreau, J / Bouhova-Thacker, E V / Boumediene, D / Bouquet, R / Boveia, A / Boyd, J / Boye, D / Boyko, I R / Bracinik, J / Brahimi, N / Brandt, G / Brandt, O / Braren, F / Brau, B / Brau, J E / Brener, R / Brenner, L / Brenner, R / Bressler, S / Britton, D / Britzger, D / Brock, I / Brooijmans, G / Brooks, W K / Brost, E / Brown, L M / Bruce, L E / Bruckler, T L / Bruckman de Renstrom, P A / Brüers, B / Bruni, A / Bruni, G / Bruschi, M / Bruscino, N / Buanes, T / Buat, Q / Buchin, D / Buckley, A G / Bulekov, O / Bullard, B A / Burdin, S / Burgard, C D / Burger, A M / Burghgrave, B / Burlayenko, O / Burr, J T P / Burton, C D / Burzynski, J C / Busch, E L / Büscher, V / Bussey, P J / Butler, J M / Buttar, C M / Butterworth, J M / Buttinger, W / Buxo Vazquez, C J / Buzykaev, A R / Cabrera Urbán, S / Cadamuro, L / Caforio, D / Cai, H / Cai, Y / Cairo, V M M / Cakir, O / Calace, N / Calafiura, P / Calderini, G / Calfayan, P / Callea, G / Caloba, L P / Calvet, D / Calvet, S / Calvet, T P / Calvetti, M / Camacho Toro, R / Camarda, S / Camarero Munoz, D / Camarri, P / Camerlingo, M T / Cameron, D / Camincher, C / Campanelli, M / Camplani, A / Canale, V / Canesse, A / Cantero, J / Cao, Y / Capocasa, F / Capua, M / Carbone, A / Cardarelli, R / Cardenas, J C J / Cardillo, F / Carli, T / Carlino, G / Carlotto, J I / Carlson, B T / Carlson, E M / Carminati, L / Carnelli, A / Carnesale, M / Caron, S / Carquin, E / Carrá, S / Carratta, G / Carrio Argos, F / Carter, J W S / Carter, T M / Casado, M P / Caspar, M / Castiglia, E G / Castillo, F L / Castillo Garcia, L / Castillo Gimenez, V / Castro, N F / Catinaccio, A / Catmore, J R / Cavaliere, V / Cavalli, N / Cavasinni, V / Cekmecelioglu, Y C / Celebi, E / Celli, F / Centonze, M S / Cepaitis, V / Cerny, K / Cerqueira, A S / Cerri, A / Cerrito, L / Cerutti, F / Cervato, B / Cervelli, A / Cesarini, G / Cetin, S A / Chadi, Z / Chakraborty, D / Chan, J / Chan, W Y / Chapman, J D / Chapon, E / Chargeishvili, B / Charlton, D G / Charman, T P / Chatterjee, M / Chauhan, C / Chekanov, S / Chekulaev, S V / Chelkov, G A / Chen, A / Chen, B / Chen, H / Chen, J / Chen, M / Chen, S / Chen, S J / Chen, X / Chen, Y / Cheng, C L / Cheng, H C / Cheong, S / Cheplakov, A / Cheremushkina, E / Cherepanova, E / Cherkaoui El Moursli, R / Cheu, E / Cheung, K / Chevalier, L / Chiarella, V / Chiarelli, G / Chiedde, N / Chiodini, G / Chisholm, A S / Chitan, A / Chitishvili, M / Chizhov, M V / Choi, K / Chomont, A R / Chou, Y / Chow, E Y S / Chowdhury, T / Chu, K L / Chu, M C / Chu, X / Chudoba, J / Chwastowski, J J / Cieri, D / Ciesla, K M / Cindro, V / Ciocio, A / Cirotto, F / Citron, Z H / Citterio, M / Ciubotaru, D A / Ciungu, B M / Clark, A / Clark, P J / Clavijo Columbie, J M / Clawson, S E / Clement, C / Clercx, J / Clissa, L / Coadou, Y / Cobal, M / Coccaro, A / Barrue, R F Coelho / Coelho Lopes De Sa, R / Coelli, S / Cohen, H / Coimbra, A E C / Cole, B / Collot, J / Conde Muiño, P / Connell, M P / 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Pinoargote, A E / Pintucci, L / Piper, K M / Pirttikoski, A / Pizzi, D A / Pizzimento, L / Pizzini, A / Pleier, M-A / Plesanovs, V / Pleskot, V / Plotnikova, E / Poddar, G / Poettgen, R / Poggioli, L / Pokharel, I / Polacek, S / Polesello, G / Poley, A / Polifka, R / Polini, A / Pollard, C S / Pollock, Z B / Polychronakos, V / Pompa Pacchi, E / Ponomarenko, D / Pontecorvo, L / Popa, S / Popeneciu, G A / Poreba, A / Portillo Quintero, D M / Pospisil, S / Postill, M A / Postolache, P / Potamianos, K / Potepa, P A / Potrap, I N / Potter, C J / Potti, H / Poulsen, T / Poveda, J / Pozo Astigarraga, M E / Prades Ibanez, A / Pretel, J / Price, D / Primavera, M / Principe Martin, M A / Privara, R / Procter, T / Proffitt, M L / Proklova, N / Prokofiev, K / Proto, G / Protopopescu, S / Proudfoot, J / Przybycien, M / Przygoda, W W / Puddefoot, J E / Pudzha, D / Pyatiizbyantseva, D / Qian, J / Qichen, D / Qin, Y / Qiu, T / Quadt, A / Queitsch-Maitland, M / Quetant, G / Quinn, R P / Rabanal 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Physical review letters

2024 Volume 132, Issue 8, Page(s) 81801

Abstract: ... with at least one electron or muon are selected from 140 fb^{-1} of pp collisions at sqrt[s]=13 TeV recorded ...

Abstract	Searches for new resonances are performed using an unsupervised anomaly-detection technique. Events with at least one electron or muon are selected from 140 fb^{-1} of pp collisions at sqrt[s]=13 TeV recorded by ATLAS at the Large Hadron Collider. The approach involves training an autoencoder on data, and subsequently defining anomalous regions based on the reconstruction loss of the decoder. Studies focus on nine invariant mass spectra that contain pairs of objects consisting of one light jet or b jet and either one lepton (e,μ), photon, or second light jet or b jet in the anomalous regions. No significant deviations from the background hypotheses are observed. Limits on contributions from generic Gaussian signals with various widths of the resonance mass are obtained for nine invariant masses in the anomalous regions.
Language	English
Publishing date	2024-02-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.132.081801
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Article ; Online: Pathways Through Early Psychosis Care for U.S. Youths From Ethnically and Racially Minoritized Groups: A Systematic Review.

Myers, Neely / Hutnyan, Matthew / Daley, Tamara C / Bello, Iruma / Chacon, Marne / Currie, Ariel / Davis, Beshaun J / Dixon, Lisa B / George, Preethy E / Giannicchi, Anna / Kwashie, Anita N / McCormick, Katie A / Meyer-Kalos, Piper / Nagendra, Arundati / Nayar, Swati / Sarpal, Deepak K / Sepahpour, Tiana Y / Shapiro, Daniel I / Taylor-Zoghby, Jessica

Psychiatric services (Washington, D.C.)

2023 Volume 74, Issue 8, Page(s) 859–868

Abstract: Objective: The authors of this systematic review examined service utilization and outcomes among youths from ethnoracially minoritized groups after the youths initiated treatment for a psychotic disorder-that is, the youths' "pathway through care." Also ...

Abstract	Objective: The authors of this systematic review examined service utilization and outcomes among youths from ethnoracially minoritized groups after the youths initiated treatment for a psychotic disorder-that is, the youths' "pathway through care." Also examined were potential moderating variables in pathways through care for these youths at the clinic, family, and cultural levels. The goal was to describe methodologies, summarize relevant findings, highlight knowledge gaps, and propose future research on pathways through care for young persons from ethnoracially minoritized groups who experience early psychosis. Methods: The PubMed, PsycInfo, and Web of Science literature databases were systematically searched for studies published between January 1, 2010, and June 1, 2021. Included articles were from the United States and focused on young people after they initiated treatment for early psychosis. Eighteen studies met inclusion criteria. Results: Sixteen of the 18 studies were published in the past 5 years, and 11 had an explicit focus on race and ethnicity as defined by the studies' authors. Studies varied in terminology, outcomes measures, methodologies, and depth of analysis. Being an individual from an ethnoracially minoritized group appeared to affect care utilization and outcomes. Insufficient research was found about potential moderating variables at the clinic, family, and cultural levels. Conclusions: Studies of pathways through care for persons from minoritized groups warrant further funding and attention.
MeSH term(s)	Humans ; Adolescent ; United States ; Psychotic Disorders/therapy ; Ethnicity
Language	English
Publishing date	2023-02-15
Publishing country	United States
Document type	Systematic Review ; Journal Article ; Review ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	1220173-x
ISSN	1557-9700 ; 1075-2730
ISSN (online)	1557-9700
ISSN	1075-2730
DOI	10.1176/appi.ps.20220121
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Article ; Online: Response to Corona-Rodarte et al.'s "Pressure alopecias: a review".

Novice, Madison / Shapiro, Jerry / Lo Sicco, Kristen I

Journal of the American Academy of Dermatology

2023 Volume 89, Issue 6, Page(s) e285–e287

MeSH term(s)	Humans ; Alopecia ; Folliculitis
Language	English
Publishing date	2023-08-28
Publishing country	United States
Document type	Review ; Letter ; Comment
ZDB-ID	603641-7
ISSN	1097-6787 ; 0190-9622
ISSN (online)	1097-6787
ISSN	0190-9622
DOI	10.1016/j.jaad.2023.08.062
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Article ; Online: Cancer Screening Test Use-U.S., 2019.

Sabatino, Susan A / Thompson, Trevor D / White, Mary C / Shapiro, Jean A / Clarke, Tainya C / Croswell, Jennifer M / Richardson, Lisa C

American journal of preventive medicine

2022 Volume 63, Issue 3, Page(s) 431–439

Abstract: Introduction: The U.S. Preventive Services Task Force recommends breast, cervical, and ...

Abstract	Introduction: The U.S. Preventive Services Task Force recommends breast, cervical, and colorectal cancer screening to reduce mortality from these cancers, but screening use has been below national targets. The purpose of this study is to examine the proportion of screening-eligible adults who are up to date with these screenings and how screening use compares with Healthy People 2020 targets. Methods: Data from the 2019 National Health Interview Survey were used to examine the percentages of adults up to date with breast cancer screening among women aged 50‒74 years without previous breast cancer, cervical cancer screening among women aged 21‒65 years without previous cervical cancer or hysterectomy, and colorectal cancer screening among adults aged 50‒75 years without previous colorectal cancer. Estimates are presented by sociodemographic characteristics and healthcare access factors. Analyses were conducted in 2021. Results: Percentages of adults up to date were 76.2% (95% CI= 75.0, 77.5) for breast cancer screening, 76.4% (95% CI= 75.2, 77.6) for cervical cancer screening, and 68.3% (95% CI= 67.3, 69.3) for colorectal cancer screening. Although some population subgroups met breast and colorectal cancer screening targets (81.1% and 70.5%, respectively), many did not, and cervical cancer screening was below the target for all examined subgroups. Lower education and income, nonmetropolitan county of residence (which included rural counties), no usual source of care or health insurance coverage, and Medicaid coverage were associated with lower screening test use. Conclusions: Estimated use of breast, cervical, and colorectal cancer screening tests based on the 2019 National Health Interview Survey were below national targets. Continued monitoring may allow for examination of screening trends, inform interventions, and track progress in eliminating disparities.
MeSH term(s)	Adult ; Breast Neoplasms/diagnosis ; Breast Neoplasms/prevention & control ; Colorectal Neoplasms/diagnosis ; Colorectal Neoplasms/prevention & control ; Early Detection of Cancer ; Female ; Humans ; Mass Screening ; United States ; Uterine Cervical Neoplasms/diagnosis ; Uterine Cervical Neoplasms/prevention & control
Language	English
Publishing date	2022-04-22
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	632646-8
ISSN	1873-2607 ; 0749-3797
ISSN (online)	1873-2607
ISSN	0749-3797
DOI	10.1016/j.amepre.2022.02.018
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Article ; Online: U.S. National Park visitor perceptions and behavioral intentions towards actions to prevent white-nose syndrome.

Shapiro, Hannah G / Willcox, Adam S / Willcox, Emma V / Verant, Michelle L

PloS one

2022 Volume 17, Issue 11, Page(s) e0278024

Abstract: ... how bats and caves are managed. The U.S. National Park Service has been instrumental in the national ... data were collected using an on-site survey of 1365 visitors to eight U.S. national park units: Oregon ... supported and promote conservation of bat populations in U.S. national parks. ...

Abstract	In the United States, the discovery and spread of white-nose syndrome (WNS) has drastically changed how bats and caves are managed. The U.S. National Park Service has been instrumental in the national response to WNS, as it manages extensive cave resources and has a close relationship with the public. However, managers lack information on visitor support for disease prevention measures designed to slow the spread of WNS and minimize human disturbance of vulnerable bat populations. This study utilized the Theory of Planned Behavior to determine how visitor attitudes, subjective norms, and perceived behavioral controls influenced their behavior regarding WNS preventive actions, including participation in educational programming on bats, wearing clothes or shoes in caves that have not been contaminated with the fungus that causes WNS, walking over decontamination mats, and complying with cave closures. During summer of 2019, data were collected using an on-site survey of 1365 visitors to eight U.S. national park units: Oregon Caves, Lava Beds, Carlsbad Caverns, El Malpais, Wind Cave, Jewel Cave, Mammoth Cave, and Cumberland Gap. Visitors were willing to participate in all preventative actions addressed in the survey (77.7%-96.7%). Visitors expressed that engaging in these actions was very desirable (36.0%-65.6%), and their decision to engage in these actions was most strongly influenced by park staff (39.2%-68.8%) or signage (35.5%-61.9%). Attitudes and subjective norms were positive predictors of behavioral intentions for all measures. Perceived behavioral control was not a direct predictor for behavioral intent, but its interaction with attitudes and subjective norms had a moderating influence on intention to comply with multiple WNS preventive actions. With the continued spread of WNS and emergence of other threats to bats, understanding visitor behavioral intent and underlying factors will facilitate successful implementation of preventive actions that are publicly supported and promote conservation of bat populations in U.S. national parks.
MeSH term(s)	Animals ; United States ; Humans ; Chiroptera/microbiology ; Intention ; Parks, Recreational ; Ascomycota ; Nose ; Syndrome
Language	English
Publishing date	2022-11-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0278024
Database	MEDical Literature Analysis and Retrieval System OnLINE

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