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Article: [CSF filtration and interferon-beta for Guillain-Barré syndrome].

Odaka, Masaaki

Nihon rinsho. Japanese journal of clinical medicine

2008 Volume 66, Issue 6, Page(s) 1200–1204

Abstract: Cerebrospinal fluid (CSF) filtration has been proposed as a new treatment for Guillain-Barré syndrome (GBS). The theory behind filtering the CSF is that soluble pathogenetic factors or inflammatory mediators including cytokines might be removed from a ... ...

Abstract	Cerebrospinal fluid (CSF) filtration has been proposed as a new treatment for Guillain-Barré syndrome (GBS). The theory behind filtering the CSF is that soluble pathogenetic factors or inflammatory mediators including cytokines might be removed from a site where nerve conduction could be impeded or nerve root damage inflicted. There is no pathologic background to recommend continuing with CSF filtration in GBS. Interferon is an immunoregulatory cytokine that reduces relapse frequency in multiple sclerosis and ameliorates experimental autoimmune neuritis, an animal model of GBS. A trial showed that interferon beta-1a would be safe in patients with GBS, but the sample size was too small to detect anything other than a large effect.
MeSH term(s)	Cerebrospinal Fluid ; Female ; Filtration ; Guillain-Barre Syndrome/cerebrospinal fluid ; Guillain-Barre Syndrome/therapy ; Humans ; Interferon-beta/therapeutic use ; Male ; Middle Aged
Chemical Substances	Interferon-beta (77238-31-4)
Language	Japanese
Publishing date	2008-06
Publishing country	Japan
Document type	English Abstract ; Journal Article ; Review
ZDB-ID	390903-7
ISSN	0047-1852
ISSN	0047-1852
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Article: [Review of guideline on new diagnostic criteria for chronic inflammatory demyelinating polyneuropathy].

Odaka, Masaaki

No to shinkei = Brain and nerve

2006 Volume 58, Issue 9, Page(s) 771–777

MeSH term(s)	Humans ; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating/diagnosis ; Practice Guidelines as Topic
Language	Japanese
Publishing date	2006-09
Publishing country	Japan
Document type	Journal Article ; Review
ZDB-ID	390389-8
ISSN	1344-8129 ; 0006-8969 ; 1881-6096
ISSN (online)	1344-8129
ISSN	0006-8969 ; 1881-6096
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Article ; Online: Chronic inflammatory demyelinating polyneuropathy: a treatment protocol proposal.

Odaka, Masaaki

Expert review of neurotherapeutics

2006 Volume 6, Issue 3, Page(s) 365–379

Abstract: Guidelines for diagnostic criteria and treatment of chronic inflammatory demyelinating polyneuropathy (CIDP) have been proposed by a joint task force of the European Federation of Neurological Societies and the Peripheral Nerve Society, based on ... ...

Abstract	Guidelines for diagnostic criteria and treatment of chronic inflammatory demyelinating polyneuropathy (CIDP) have been proposed by a joint task force of the European Federation of Neurological Societies and the Peripheral Nerve Society, based on available evidence and expert consensus. These should prove practical for the clinical management of CIDP. Intravenous immunoglobulin followed by corticosteroids should be considered as the initial treatment, however no clear second drug of choice for patients who do not respond to the initial treatment is given. The author reports the long-term therapeutic efficacy of ciclosporin for patients with CIDP who did not show sustained improvement under steroid therapy. Ciclosporin should be tried for patients with intractable CIDP who require repeated intravenous immunoglobulin. An adequate initial dose of ciclosporin is 3 mg/kg/day, with plasma trough concentrations between 100 and 150 ng/ml. If patients respond to ciclosporin, remission can be maintained for 2 years, after which the dose can be slowly reduced over 1 year. Eventual withdrawal should be considered. This review proposes a treatment strategy that includes long-term maintenance therapy for CIDP based on published clinical trials and the author's clinical experience. Current concepts concerning the clinical spectrum of CIDP and diagnostic approaches are also considered.
MeSH term(s)	Clinical Protocols ; Diagnosis, Differential ; Humans ; Patient Care Planning ; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating/diagnosis ; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating/drug therapy ; Practice Guidelines as Topic
Language	English
Publishing date	2006-03
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2112534-X
ISSN	1744-8360 ; 1473-7175
ISSN (online)	1744-8360
ISSN	1473-7175
DOI	10.1586/14737175.6.3.365
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Article ; Online: Localization of T-cell factor 4 positive fibroblasts and CD206-positive macrophages during skeletal muscle regeneration in mice.

Ogawa, Yudai / Yamamoto, Masahito / Sato, Masaki / Odaka, Kento / Kasahara, Masaaki / Hinata, Nobuyuki / Sakiyama, Koji / Abe, Shinichi

Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft

2021 Volume 235, Page(s) 151694

Abstract: Skeletal muscle regeneration is initiated by the activation of the transcription factor paired box 7 (Pax7), which is expressed in the satellite cells. The nuclear transcription factor T-cell factor 4 (Tcf4) is expressed in the fibroblasts and is ... ...

Abstract	Skeletal muscle regeneration is initiated by the activation of the transcription factor paired box 7 (Pax7), which is expressed in the satellite cells. The nuclear transcription factor T-cell factor 4 (Tcf4) is expressed in the fibroblasts and is involved in muscle tissue repair, while M2-like macrophages play an important role in skeletal muscle regeneration. However, the localization of M2-like macrophages and the expression of Tcf4 over a period of time during skeletal muscle regeneration remain unknown. Therefore, the murine masseter muscle was immunofluorescence investigated for the surface protein CD206 of M2-like macrophages and Tcf4 of fibroblasts during skeletal muscle regeneration to understand the changes in the CD206 and Tcf4 expression over time. We observed that CD206 entered the cytoplasm of some regenerating muscle fibers 5-7 days after the experimental muscle damage, that is, in the early stage of maturation of the regenerating muscle fibers with central nuclei. In addition, Tcf4 was expressed in the nuclei of the fibroblasts around the regenerating muscle fibers and in the central nuclei of the regenerating muscle fibers. Furthermore, the expression of laminin adjacent to Tcf4-positive cells was observed to partially disappear, and the shape of this missing part was observed to be identical to that of the nuclei of Tcf4-positive cells adjacent to the laminin. Clathrin was also expressed in these sites, demonstrating endocytosis. Thus, these results suggest that in the early stage of maturation of the regenerating muscle fibers, M2-like macrophages and Tcf4-positive fibroblasts enter the cytoplasm of the regenerating muscle fibers, thereby regulating the expression of various maturation factors.
MeSH term(s)	Animals ; Fibroblasts ; Macrophages ; Mice ; Muscle Fibers, Skeletal ; Muscle, Skeletal ; Regeneration ; Transcription Factor 7-Like 2 Protein
Chemical Substances	Transcription Factor 7-Like 2 Protein
Language	English
Publishing date	2021-02-08
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1106738-x
ISSN	1618-0402 ; 0940-9602
ISSN (online)	1618-0402
ISSN	0940-9602
DOI	10.1016/j.aanat.2021.151694
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Article: [Plasmapheresis for Guillain-Barré syndrome and chronic inflammatory demyelinating polyneuropathy].

Odaka, Masaaki

Nihon rinsho. Japanese journal of clinical medicine

2004 Volume 62 Suppl 5, Page(s) 491–495

MeSH term(s)	Autoantibodies/isolation & purification ; Evidence-Based Medicine ; Gangliosides/immunology ; Guillain-Barre Syndrome/etiology ; Guillain-Barre Syndrome/therapy ; Humans ; Immunoglobulin G/isolation & purification ; Immunoglobulin M/immunology ; Immunoglobulins, Intravenous/therapeutic use ; Myelin-Associated Glycoprotein/immunology ; Plasma Exchange/adverse effects ; Plasma Exchange/methods
Chemical Substances	Autoantibodies ; Gangliosides ; Immunoglobulin G ; Immunoglobulin M ; Immunoglobulins, Intravenous ; Myelin-Associated Glycoprotein
Language	Japanese
Publishing date	2004-05
Publishing country	Japan
Document type	Journal Article ; Review
ZDB-ID	390903-7
ISSN	0047-1852
ISSN	0047-1852
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Zs.A 429: Show issues

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Article ; Online: Micro- and nano-bone analyses of the human mandible coronoid process and tendon-bone entheses.

Kasahara, Masaaki / Matsunaga, Satoru / Someya, Tomoko / Kitamura, Kei / Odaka, Kento / Ishimoto, Takuya / Nakano, Takayoshi / Abe, Shinichi / Hattori, Masayuki

Journal of biomedical materials research. Part B, Applied biomaterials

2020 Volume 108, Issue 7, Page(s) 2799–2806

Abstract: The coronoid process provides attachment to temporalis and masseter muscles, and thus plays an important role in mastication. Tendons connect muscles and bones, mediating the transmission of functional loads to bones. Thus, tendon-bone entheses govern ... ...

Abstract	The coronoid process provides attachment to temporalis and masseter muscles, and thus plays an important role in mastication. Tendons connect muscles and bones, mediating the transmission of functional loads to bones. Thus, tendon-bone entheses govern mechanical stress in bones. The preferential orientation of biological apatite (BAp) crystallites, the main mineral component in bones, is an important index for bone quality and function, and is largely influenced by locally applied stress. In this study, we analyzed BAp orientation, Young's modulus, and bone mineral density (BMD) at different sites in the human coronoid process. No differences in BMD were found among the analyzed sites, but BAp crystal orientation was observed to differ. BAp crystallites showed a uni-directional orientation in the mesiodistal direction at the coronoid process apex, but were oriented in the direction vertical to the occlusal plane at other sites. Young's modulus tended to vary according to the BAp orientation. At the apex, a tendon form with characteristics different from those at other sites, including the presence of a fibrocartilaginous layer that may act as a stretching brake to control stress concentration, was observed. These findings suggest that the functional pressure of the temporalis muscle affects bone quality and strength.
MeSH term(s)	Aged ; Aged, 80 and over ; Bone Density ; Female ; Fibrocartilage/chemistry ; Humans ; Male ; Mandible/chemistry ; Stress, Mechanical ; Tendons/chemistry
Language	English
Publishing date	2020-03-19
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2099992-6
ISSN	1552-4981 ; 1552-4973 ; 0021-9304
ISSN (online)	1552-4981
ISSN	1552-4973 ; 0021-9304
DOI	10.1002/jbm.b.34609
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Article ; Online: Nodal proteins are target antigens in Guillain-Barré syndrome.

Devaux, Jérôme J / Odaka, Masaaki / Yuki, Nobuhiro

Journal of the peripheral nervous system : JPNS

2012 Volume 17, Issue 1, Page(s) 62–71

Abstract: Neurofascin-186 (NF186), neuronal cell adhesion molecule (NrCAM), and gliomedin are adhesion molecules playing a central role in the formation of nodes of Ranvier. In Guillain-Barré syndrome (GBS), immune attack toward the nodes may participate in the ... ...

Abstract	Neurofascin-186 (NF186), neuronal cell adhesion molecule (NrCAM), and gliomedin are adhesion molecules playing a central role in the formation of nodes of Ranvier. In Guillain-Barré syndrome (GBS), immune attack toward the nodes may participate in the disabilities. Autoantibodies to NF186 and gliomedin have been detected in a rat model of GBS. Here, we investigated the prevalence of antibodies against nodal adhesion molecules in patients with GBS or chronic inflammatory demyelinating polyneuropathy (CIDP). Sera from 100 GBS patients, 50 CIDP patients, 80 disease controls, and 50 healthy controls were tested for their ability to bind the nodes of Ranvier. To characterize the antigens, we performed cell binding assays against NF186, gliomedin, contactin, and NrCAM. We found that 43% of patients with GBS and 30% of patients with CIDP showed IgG fixation at nodes or paranodes. In eight patients with GBS or CIDP, we identified that IgG antibodies recognized the native extracellular domain of NF186, gliomedin, or contactin. Also, 29 patients showed IgM against nodal adhesion molecules. However, we did not detect IgM fixation at nodes or paranodes. Antibodies to gliomedin or NF186 were mostly detected in demyelinating and axonal GBS, respectively. The adsorption of the antibodies to their soluble antigens abolished IgG deposition at nodes and paranodes in nerves, indicating these were specific to NF186, gliomedin, and contactin. In conclusion, gliomedin, NF186, and contactin are novel target antigens in GBS. At nodes, additional epitopes are also the targets of IgG. These results suggest that antibody attack against nodal antigens participates in the etiology of GBS.
MeSH term(s)	Adolescent ; Adult ; Aged ; Autoantibodies/blood ; Autoantibodies/immunology ; Autoantigens/immunology ; Cell Adhesion Molecules/immunology ; Child ; Child, Preschool ; Contactins/immunology ; Female ; Guillain-Barre Syndrome/blood ; Guillain-Barre Syndrome/immunology ; Humans ; Immunoglobulin G/immunology ; Infant ; Male ; Membrane Proteins ; Middle Aged ; Nerve Growth Factors/immunology ; Nerve Tissue Proteins ; Neural Cell Adhesion Molecules/immunology ; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating/blood ; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating/immunology ; Ranvier's Nodes/immunology ; Young Adult
Chemical Substances	Autoantibodies ; Autoantigens ; Cell Adhesion Molecules ; Contactins ; GLDN protein, human ; Immunoglobulin G ; Membrane Proteins ; NFASC protein, human ; Nerve Growth Factors ; Nerve Tissue Proteins ; Neural Cell Adhesion Molecules
Language	English
Publishing date	2012-03
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1364009-4
ISSN	1529-8027 ; 1085-9489
ISSN (online)	1529-8027
ISSN	1085-9489
DOI	10.1111/j.1529-8027.2012.00372.x
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Article: [A case of unilateral thalamic and striatal lesions associated with deep venous thrombosis].

Niijima, Yuko / Odaka, Masaaki / Nakamura, Toshiki / Hirata, Koichi

Brain and nerve = Shinkei kenkyu no shinpo

2010 Volume 62, Issue 2, Page(s) 177–179

MeSH term(s)	Corpus Striatum/pathology ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Thalamus/pathology ; Tomography, X-Ray Computed ; Venous Thrombosis/pathology
Language	Japanese
Publishing date	2010-02
Publishing country	Japan
Document type	Case Reports ; Journal Article
ZDB-ID	390389-8
ISSN	1344-8129 ; 1881-6096 ; 0006-8969
ISSN (online)	1344-8129
ISSN	1881-6096 ; 0006-8969
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Article: Three-dimensional analysis of incisive canals in human dentulous and edentulous maxillary bones.

Fukuda, Masayuki / Matsunaga, Satoru / Odaka, Kento / Oomine, Yuuya / Kasahara, Masaaki / Yamamoto, Masahito / Abe, Shinichi

International journal of implant dentistry

2015 Volume 1, Issue 1, Page(s) 12

Abstract: Background: The purpose of this study was to reveal the structural properties that need to be considered in dental implant treatment by investigating differences between dentulous and edentulous maxillae in the three-dimensional (3D) microstructure of ... ...

Abstract	Background: The purpose of this study was to reveal the structural properties that need to be considered in dental implant treatment by investigating differences between dentulous and edentulous maxillae in the three-dimensional (3D) microstructure of the incisive canals (ICs) and their surrounding bone. Methods: A total of 40 maxillary bones comprising 20 dentulous maxillae and 20 edentulous maxillae were imaged by micro-CT for 3D observation and measurement of the IC and alveolar bone in the anterior region of the IC. Results: The Y-morphology canal was most frequently observed at 60% in dentulous maxilla and 55% in edentulous maxilla. There was a significant difference between dentulous and edentulous maxillae in IC diameter and volume, but no significant difference between the two in the major axis of the ICs. Conclusions: The anatomic structure surrounding the IC has limited area for implant placement. Therefore, where esthetic and long-term maintenance requirements are taken into account, careful attention is needed when setting the placement position. Also, due to the resorption of bone, edentulous maxillae have a different IC morphology from dentulous maxillae, and therefore, a cautious approach is required.
Language	English
Publishing date	2015-05-01
Publishing country	Germany
Document type	Journal Article
ISSN	2198-4034
ISSN	2198-4034
DOI	10.1186/s40729-015-0012-4
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Article ; Online: Histological study of the developing pterygoid process of the fetal mouse sphenoid.

Yamamoto, Masahito / Kitamura, Kei / Kasahara, Masaaki / Serikawa, Masamitsu / Katumura, Sakura / Yoshimoto, Toshihito / Matubayashi, Tadatoshi / Odaka, Kento / Matsunaga, Satoru / Abe, Shinichi

Anatomical science international

2017 Volume 92, Issue 3, Page(s) 364–372

Abstract: The pterygoid process undergoes ossification of both the cartilage and membrane. However, few studies have attempted to explore the sequential development of the pterygoid process. Using histological examination, we performed morphological observations ... ...

Abstract	The pterygoid process undergoes ossification of both the cartilage and membrane. However, few studies have attempted to explore the sequential development of the pterygoid process. Using histological examination, we performed morphological observations of the pterygoid process and surrounding tissue. ICR mice at embryonic days 13.5-18.0 and postnatal day 0 were used for morphological observations of the pterygoid process. By embryonic day 14.5, a mesenchymal cell condensation forming the anlage of the future medial pterygoid process differentiated into osteoid-like tissue and cartilage. At embryonic days 15.5-16.5, cartilage cells were clearly evident in the medial pterygoid process. In the medial pterygoid process, a bone collar was evident and calcified bone tissue surrounded the cartilage. At this point, a mesenchymal cell condensation formed the anlage of the pterygoid hamulus. At embryonic days 17.0-18.0, the cartilages were located along the lower and posterior border of the medial pterygoid process. A metachromatically stained matrix first became detectable around cells located in the pterygoid hamulus. On the other hand, at embryonic day 13.5, a metachromatically stained matrix was already evident in the space between the flattened cells in the lateral pterygoid process. At embryonic day 17.0, a hypertrophic cell zone had clearly formed in the diaphysis. On the basis of our present investigation, the lateral pterygoid process can be classified as primary cartilage, whereas the medial pterygoid process can be classified as secondary cartilage. Furthermore, it was found that the pterygoid hamulus is formed latest in the medial pterygoid process.
MeSH term(s)	Animals ; Cartilage/anatomy & histology ; Cartilage/embryology ; Female ; Mice, Inbred ICR ; Osteogenesis ; Pregnancy ; Sphenoid Bone/anatomy & histology ; Sphenoid Bone/embryology
Language	English
Publishing date	2017-06
Publishing country	Japan
Document type	Journal Article
ZDB-ID	2079994-9
ISSN	1447-073X ; 1447-6959 ; 0022-7722
ISSN (online)	1447-073X
ISSN	1447-6959 ; 0022-7722
DOI	10.1007/s12565-016-0340-3
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