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  1. Article: Bidirectional Relationship between COVID-19 and Diabetes: Role of Renin-Angiotensin-Aldosterone System and Drugs Modulating It.

    Khanam, Razia

    Journal of pharmacy & bioallied sciences

    2021  Volume 13, Issue 2, Page(s) 149–154

    Abstract: Numerous reports have suggested that diabetic patients are at high risk for the development of severe symptoms of coronavirus disease-2019 (COVID-19). However, a few studies have recently proposed that the relationship between diabetes and COVID-19 is ... ...

    Abstract Numerous reports have suggested that diabetic patients are at high risk for the development of severe symptoms of coronavirus disease-2019 (COVID-19). However, a few studies have recently proposed that the relationship between diabetes and COVID-19 is bidirectional, as severe acute respiratory syndrome-coronavirus-2 also has the capability to induce diabetes. Various mechanisms have been identified and proposed to be involved in this binary association. In this review, the importance and impact of renin-angiotensin-aldosterone system (RAAS) in this two-way association of COVID-19 and diabetes has been summarized. The role and effect of drugs modulating RAAS directly or indirectly has also been discussed, as they can majorly impact the course of treatment in such patients. Further reports and data can present a clear picture of RAAS and its modulators in restoring the balance of dysregulated RAAS in COVID-19.
    Language English
    Publishing date 2021-05-26
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 2573569-X
    ISSN 0975-7406 ; 0976-4879
    ISSN (online) 0975-7406
    ISSN 0976-4879
    DOI 10.4103/jpbs.JPBS_508_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Bidirectional relationship between covid-19 and diabetes

    Razia Khanam

    Journal of Pharmacy and Bioallied Sciences, Vol 13, Iss 2, Pp 149-

    Role of renin–angiotensin–aldosterone system and drugs modulating it

    2021  Volume 154

    Abstract: Numerous reports have suggested that diabetic patients are at high risk for the development of severe symptoms of coronavirus disease-2019 (COVID-19). However, a few studies have recently proposed that the relationship between diabetes and COVID-19 is ... ...

    Abstract Numerous reports have suggested that diabetic patients are at high risk for the development of severe symptoms of coronavirus disease-2019 (COVID-19). However, a few studies have recently proposed that the relationship between diabetes and COVID-19 is bidirectional, as severe acute respiratory syndrome-coronavirus-2 also has the capability to induce diabetes. Various mechanisms have been identified and proposed to be involved in this binary association. In this review, the importance and impact of renin–angiotensin–aldosterone system (RAAS) in this two-way association of COVID-19 and diabetes has been summarized. The role and effect of drugs modulating RAAS directly or indirectly has also been discussed, as they can majorly impact the course of treatment in such patients. Further reports and data can present a clear picture of RAAS and its modulators in restoring the balance of dysregulated RAAS in COVID-19.
    Keywords beta receptor antagonists ; coronavirus ; diabetes ; renin–angiotensin–aldosterone system ; Pharmacy and materia medica ; RS1-441 ; Analytical chemistry ; QD71-142
    Subject code 610
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Common factors influencing childhood undernutrition and their comparison between Sylhet, the most vulnerable region, and other parts of Bangladesh: Evidence from BDHS 2007-18 rounds.

    Sanin, Kazi Istiaque / Khanam, Mansura / Rita, Razia Sultana / Haque, Md Ahshanul / Ahmed, Tahmeed

    Frontiers in nutrition

    2023  Volume 9, Page(s) 999520

    Abstract: Introduction: Undernourishment is disproportionately spread within Bangladesh, making some regions like Sylhet more vulnerable than the rest of the country. We aimed to assess the trend of diverse associated factors related to childhood stunting, ... ...

    Abstract Introduction: Undernourishment is disproportionately spread within Bangladesh, making some regions like Sylhet more vulnerable than the rest of the country. We aimed to assess the trend of diverse associated factors related to childhood stunting, wasting, and being underweight. Furthermore, we have compared the estimated factors between Sylhet, the most vulnerable region, and other parts of Bangladesh.
    Methods: We performed a secondary data analysis where data were derived from the nationally representative cross-sectional surveys: Bangladesh demographic and health survey (BDHS) 2007, 2011, 2014, and 2017-18 rounds. The outcome variables were childhood undernutrition, including stunting, wasting, and being underweight. Descriptive statistics such as mean, standard deviation, frequency, and proportion were used to summarize the data. All variables were summarized by BDHS survey time points. We used multiple logistic regression models to measure the associated factors with childhood stunting, wasting, and being underweight.
    Results: The percentage of children under the age of 5 years who were stunted declined from 40% in 2007 to 31% in 2018. Similar trends are observed in the decrease in the percentage of underweight children, dropping from 39% in 2007 to 22% in 2018. Wasting dropped to 8% in 2018 after years of critically high levels (17%). According to the results of the regression analyses, urban residence, child's age and gender, morbidity, maternal BMI, maternal and paternal education, decision-making ability, use of contraceptives, the occurrence of domestic violence, antenatal care, c-section, and birth interval, as well as geographic region, were all linked to childhood malnutrition.
    Conclusion: The Sylhet division falls short in several critical associated indicators, including parental education, maternal BMI, obtaining at least four ANC, women empowerment, and usage of contraceptives. Policymakers must concentrate on region-specific planning and proper intervention to achieve a more uniform improvement across the country.
    Language English
    Publishing date 2023-01-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2776676-7
    ISSN 2296-861X
    ISSN 2296-861X
    DOI 10.3389/fnut.2022.999520
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Heavy metals in hair and nails as markers of occupational hazard among welders working in United Arab Emirates.

    Lotah, Hisaa Nassir Abdulla / Agarwal, Anoop Kumar / Khanam, Razia

    Toxicological research

    2021  Volume 38, Issue 1, Page(s) 63–68

    Abstract: Studies have shown that hair and nail samples can be used as a marker to assess occupational exposure to heavy metals. The objective of this study was to estimate the levels of heavy metals: Lead (Pb), Nickel (Ni), Cadmium (Cd), and Manganese (Mn) in ... ...

    Abstract Studies have shown that hair and nail samples can be used as a marker to assess occupational exposure to heavy metals. The objective of this study was to estimate the levels of heavy metals: Lead (Pb), Nickel (Ni), Cadmium (Cd), and Manganese (Mn) in hair and nail samples of welders working in United Arab Emirates and to find an association between the heavy metal concentration with the parameters like smoking habits, exposure/day, years of experience and use of protective personal equipment (PPE). Hair and toes nail samples were collected from exposed and non-exposed subjects with respect to, social habits, exposure/day and years of welding experience. The levels of Pb, Cd, Mn, and Ni, in hair and toenails, assayed by atomic absorption spectrophotometer. We observed that the metal concentration was higher in toenail as compared to hair samples in both the groups. Cd was significantly high in both the groups whereas, Mn in the hair was high in the exposed group. The Mn in hair was notably higher among smokers and the Cd in hair and Ni in the nail samples was significantly higher in the subjects with > 8 h/day exposure. The concentration of Cd and Ni in hair increased with increasing years of experience and was maximum in the subjects with welding experience of > 20 years. Our results signify that hair and nail samples can be used as an indicator to heavy metal exposure. Given that the present study shows high level of some metals in the hair and nail of welders, awareness of occupational hazards and annual assessment of welder's health is necessary.
    Language English
    Publishing date 2021-02-17
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 2727978-9
    ISSN 2234-2753 ; 1976-8257
    ISSN (online) 2234-2753
    ISSN 1976-8257
    DOI 10.1007/s43188-021-00091-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Maxillary dental arch width changes by extraction and non-extraction orthodontic treatment among angle’s class I malocclusion patients

    Sultana Razia Khanam / Ranjit Ghosh / Gazi Shamim Hassan / Mozammal Hossain

    Update Dental College Journal, Vol 12, Iss 2, Pp 24-

    2022  Volume 26

    Abstract: This study examined the pretreatment and post treatment dental arch width changes between the extraction and non-extraction cases in Angle’s class I patients. Sixty pre-treatment and post-treatment dental casts from 30 extractions and 30 non-extractions ... ...

    Abstract This study examined the pretreatment and post treatment dental arch width changes between the extraction and non-extraction cases in Angle’s class I patients. Sixty pre-treatment and post-treatment dental casts from 30 extractions and 30 non-extractions participants were selected for the study. The inter-canine and inter-molar maxillary arch width were measured by Vernier gauge caliper. An unpaired t-test was performed to evaluate the arch width changes between extraction and non-extraction groups. The results showed that inter-molar and inter-canine maxillary arch widths in the non-extraction group were slightly higher than those in the extraction group in both pre- and post-treatment, but the differences were not statistically significant. In conclusion, the extraction and non-extraction techniques used in orthodontic treatment did not change the inter-caning and inter-molar arch widths.
    Keywords maxillary arch width change ; extraction case ; non-extraction case ; inter-canine width ; inter-molar width ; Medicine (General) ; R5-920 ; Dentistry ; RK1-715
    Subject code 630
    Language English
    Publishing date 2022-10-01T00:00:00Z
    Publisher Update Dental College
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: COVID-19 vaccine barriers and perception among rural adults: a qualitative study in Bangladesh.

    Khanam, Mansura / Sanin, Kazi Istiaque / Rita, Razia Sultana / Akand, Farhana / Rabbi, Md Fozla / Hasan, Md Khaledul / Alam, Tasnia / Ahmed, Tahmeed

    BMJ open

    2023  Volume 13, Issue 10, Page(s) e074357

    Abstract: Objective: The COVID-19 pandemic continues to pose challenges for global public healthcare, even with the authorisation of several vaccines worldwide. To better understand rural communities' knowledge, attitudes, perceptions and barriers towards these ... ...

    Abstract Objective: The COVID-19 pandemic continues to pose challenges for global public healthcare, even with the authorisation of several vaccines worldwide. To better understand rural communities' knowledge, attitudes, perceptions and barriers towards these vaccines, we conducted a qualitative cross-sectional study with adults in rural Bangladesh.
    Setting: This cross-sectional study was conducted in the rural areas of Sylhet and Natore in Bangladesh from August 2021 to February 2022.
    Participants: Our study involved 15 in-depth interviews with rural adults and 2 key informant interviews with health workers.
    Results: We analysed data thematically, resulting in four main themes: (1) knowledge and perception aspects, (2) myths and misconceptions, (3) practice and attitude and (4) barriers and challenges of COVID-19 vaccines.
    Conclusions: The findings indicate that rural populations lack sufficient knowledge about COVID-19 vaccines but have a more favourable attitude towards them. Misconceptions, beliefs and personal experiences were found to be the main reasons for vaccine avoidance. To address these challenges and dispel the spread of misinformation, health education programmes play a pivotal role in improving vaccine management. Policy-makers should initiate these programmes without delay to create a well-informed and enlightened community, given that the COVID-19 is still spreading.
    MeSH term(s) Adult ; Humans ; Bangladesh ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19 Vaccines ; Cross-Sectional Studies ; Pandemics ; Perception ; Rural Population ; Vaccines ; Qualitative Research
    Chemical Substances COVID-19 Vaccines ; Vaccines
    Language English
    Publishing date 2023-10-18
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2023-074357
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: What Makes Bangladeshi Pregnant Women More Compliant to Iron-Folic Acid Supplementation: A Nationally Representative Cross-Sectional Survey Result.

    Sanin, Kazi Istiaque / Alam Shaun, Mahbubul / Rita, Razia Sultana / Hasan, Md Khaledul / Khanam, Mansura / Haque, Md Ahshanul

    Nutrients

    2023  Volume 15, Issue 6

    Abstract: Background: Iron-Folic Acid Supplementation (IFAS) is an effective strategy to prevent iron deficiency anemia during pregnancy. We aimed to explore the key factors associated with compliance to IFA tablets in Bangladesh.: Methods: This study analyzed ...

    Abstract Background: Iron-Folic Acid Supplementation (IFAS) is an effective strategy to prevent iron deficiency anemia during pregnancy. We aimed to explore the key factors associated with compliance to IFA tablets in Bangladesh.
    Methods: This study analyzed the 2017-2018 Bangladesh Demographic and Health Survey data of 3828 pregnant women aged 15-49 years. We categorized compliance into two categories; at least 90 days and full 180 days of consumption. We performed multivariable logistic regression to identify the association between key factors and IFAS compliance.
    Results: The prevalence of consumption of IFA tablets for at least 90 days was 60.64%, and only 21.72% of women consumed the IFA for the full 180 days. About three-quarters of the women (73.36%) having at least four antenatal care visits (ANC) consumed IFA for at least 90 days, whereas only three in ten women (30.37%) consumed IFA for a minimum of 180 days. For compliance with IFA for at least 90 days, respondent's age of 20-34 years (aOR 1.26, 95% CI 1.03-1.54), respondent's educational qualification of secondary (aOR 1.77, 95% CI 1.16-2.70) or higher (aOR 2.73, 95% CI 1.65-4.53), husband's educational qualification of secondary (aOR 1.33, 95% CI 1.00-1.77) or higher (aOR 1.75, 95% CI 1.22-2.52), and having received at least four antenatal care (ANC) visits from medically skilled providers (aOR 2.53, 95% CI 2.14-3.00) were significantly associated with higher odds of compliance. For compliance with IFA for at least 180 days, respondent's educational qualification of higher (aOR 2.45, 95% CI 1.34-4.48), and having received at least four ANC visits from medically skilled providers (aOR 2.43, 95% CI 1.97-3.00) were significantly associated with higher odds of compliance. Intimate partner violence was negatively associated with compliance with IFA for at least 180 days (aOR 0.62, 95% CI 0.48-0.81).
    Conclusions: The full compliance to IFAS is still sub-optimal in Bangladesh. Further precise context-specific intervention strategies must be developed and implemented with fidelity.
    MeSH term(s) Female ; Pregnancy ; Humans ; Iron ; Pregnant Women ; Cross-Sectional Studies ; Dietary Supplements ; Folic Acid ; Prenatal Care
    Chemical Substances Iron (E1UOL152H7) ; Folic Acid (935E97BOY8)
    Language English
    Publishing date 2023-03-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15061512
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: COVID-19 vaccine barriers and perception among rural adults

    Tahmeed Ahmed / Mansura Khanam / Kazi Istiaque Sanin / Razia Sultana Rita / Farhana Akand / Md Fozla Rabbi / Md Khaledul Hasan / Tasnia Alam

    BMJ Open, Vol 13, Iss

    a qualitative study in Bangladesh

    2023  Volume 10

    Abstract: Objective The COVID-19 pandemic continues to pose challenges for global public healthcare, even with the authorisation of several vaccines worldwide. To better understand rural communities’ knowledge, attitudes, perceptions and barriers towards these ... ...

    Abstract Objective The COVID-19 pandemic continues to pose challenges for global public healthcare, even with the authorisation of several vaccines worldwide. To better understand rural communities’ knowledge, attitudes, perceptions and barriers towards these vaccines, we conducted a qualitative cross-sectional study with adults in rural Bangladesh.Setting This cross-sectional study was conducted in the rural areas of Sylhet and Natore in Bangladesh from August 2021 to February 2022.Participants Our study involved 15 in-depth interviews with rural adults and 2 key informant interviews with health workers.Results We analysed data thematically, resulting in four main themes: (1) knowledge and perception aspects, (2) myths and misconceptions, (3) practice and attitude and (4) barriers and challenges of COVID-19 vaccines.Conclusions The findings indicate that rural populations lack sufficient knowledge about COVID-19 vaccines but have a more favourable attitude towards them. Misconceptions, beliefs and personal experiences were found to be the main reasons for vaccine avoidance. To address these challenges and dispel the spread of misinformation, health education programmes play a pivotal role in improving vaccine management. Policy-makers should initiate these programmes without delay to create a well-informed and enlightened community, given that the COVID-19 is still spreading.
    Keywords Medicine ; R
    Subject code 360
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher BMJ Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Effects of

    Khanam, Mansura / Sanin, Kazi Istiaque / Ara, Gulshan / Sultana Rita, Razia / Boitchi, Anika Bushra / Farzana, Fahmida Dil / Haque, Md Ahshanul / Ahmed, Tahmeed

    Frontiers in nutrition

    2022  Volume 9, Page(s) 959890

    Abstract: Objectives: Moringa oleifera: Methods: This school-based quasi-experimental study involved 226 adolescent girls (12-14 years-old). Intervention group (: Results: Mean age of the intervention and control groups were 12.7 ± 0.7 and 13.3 ± 0.8 years, ...

    Abstract Objectives: Moringa oleifera
    Methods: This school-based quasi-experimental study involved 226 adolescent girls (12-14 years-old). Intervention group (
    Results: Mean age of the intervention and control groups were 12.7 ± 0.7 and 13.3 ± 0.8 years, respectively. After adjusting for maternal education, absenteeism, asset index, BMI-for-age Z-score, GLM regression showed significant positive changes in hemoglobin (intervention vs. control: coef = 0.41,
    Conclusion: Consumption of Moringa leaves has the potential to improving hemoglobin and serum retinol level and should be encouraged as regular diet.
    Language English
    Publishing date 2022-07-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2776676-7
    ISSN 2296-861X
    ISSN 2296-861X
    DOI 10.3389/fnut.2022.959890
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Analysis of phthalate esters in two different baby care products available in United Arab Emirates.

    Farooqi, Saba / Rajendran, K / Khanam, Razia

    Toxicology mechanisms and methods

    2018  Volume 29, Issue 1, Page(s) 60–66

    Abstract: Phthalates are used as plasticizers in a wide range of products and are known to affect the human health adversely. Hence, the present study was carried out to identify and quantify the presence of four phthalates namely dimethyl phthalate (DMP), dibutyl ...

    Abstract Phthalates are used as plasticizers in a wide range of products and are known to affect the human health adversely. Hence, the present study was carried out to identify and quantify the presence of four phthalates namely dimethyl phthalate (DMP), dibutyl phthalate (DBP), and diethyl phthalate (DEP), di (2-ethylhexyl) phthalate (DEHP) in the two baby products i.e. baby oils and baby lotions. The daily exposure levels and hazard index of each phthalate were also calculated. It was an analytical study where two different brands of samples of baby oil and baby lotion each, from the date of manufacturing of 3, 10, and 20 months were collected. The extraction of phthalates from different samples was done and analyzed using HPTLC. Results showed the presence of all four phthalates, although some phthalates were not present in 3 M samples. The maximum concentration of all the phthalates was found in 20 M samples. Their concentration increased with the storage time indicating the possibility of leaching and migration of phthalates from the container into the product. The hazard indices for phthalates estimated for baby oil and baby lotion were found below 1, which denotes that the daily phthalate exposures are within the regulatory limits. It is important to consider that the exposure to phthalates can occur not only by dermal contact of these baby products but also through other routes. Hence, the study signifies the importance of phthalates concentration in such regularly used products.
    MeSH term(s) Chromatography, High Pressure Liquid ; Cosmetics/chemistry ; Cosmetics/standards ; Dibutyl Phthalate/analysis ; Diethylhexyl Phthalate/analysis ; Environmental Exposure/analysis ; Humans ; Infant ; Infant, Newborn ; Limit of Detection ; Phthalic Acids/analysis ; Product Packaging/standards ; Risk Assessment ; United Arab Emirates
    Chemical Substances Cosmetics ; Phthalic Acids ; dimethyl phthalate (08X7F5UDJM) ; Dibutyl Phthalate (2286E5R2KE) ; Diethylhexyl Phthalate (C42K0PH13C) ; diethyl phthalate (UF064M00AF)
    Language English
    Publishing date 2018-09-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2081252-8
    ISSN 1537-6524 ; 1537-6516 ; 1051-7235
    ISSN (online) 1537-6524
    ISSN 1537-6516 ; 1051-7235
    DOI 10.1080/15376516.2018.1512179
    Database MEDical Literature Analysis and Retrieval System OnLINE

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