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  1. Article ; Online: Twelve-Year Experience With Nasofrontal Angle (Radix) Augmentation in Rhinoplasty.

    Alawadh, Ibrahim / Bogari, Ahmad / Bedaiwi, Reenad / Alanazi, Hani / Bafaqeeh, Sameer

    The Journal of craniofacial surgery

    2022  Volume 33, Issue 7, Page(s) 2019–2023

    Abstract: Abstract: The nasofrontal angle (radix) has a great impact on the rhinoplasty outcome. Minimal alterations in this area can give an unusual nasal appearance and midfacial length. Different management approaches have been described with regard to radix ... ...

    Abstract Abstract: The nasofrontal angle (radix) has a great impact on the rhinoplasty outcome. Minimal alterations in this area can give an unusual nasal appearance and midfacial length. Different management approaches have been described with regard to radix augmentation. This study aimed to describe the techniques of rhinoplasty, different materials used in the procedure, and results of at least 1 year of follow-up in our 12-year experience in this field. The authors retrospectively reviewed the data of patients who underwent rhino-plasty/septorhinoplasty with radix augmentation performed by 1 of the authors (a senior surgeon at our institution) using different graft materials, between January 2007 and December 2019. Patients younger than 18 years or who were followed up for less than 1 year were excluded from the study. In total, 387 patients (235 [60.7%] female; age range, 19-39 years) were included. Primary procedures were performed in 311 patients (80.5%), and revision procedures were performed in 76 patients (19.6%). Most patients (97%) were satisfied with the aesthetic result. There was no incidence of infection, displacement, or extrusion of the graft. The only complications observed were irregularities; 3% required revision surgery. It is important to consider the nasal radix when pursuing a balanced profile in rhinoplasty. Many graft materials can be used safely and can achieve good aesthetic outcomes. Proper anatomical analysis and patient selection are essential for successful graft placement.
    MeSH term(s) Adult ; Esthetics ; Esthetics, Dental ; Female ; Humans ; Male ; Nose/surgery ; Retrospective Studies ; Rhinoplasty/methods ; Treatment Outcome ; Young Adult
    Language English
    Publishing date 2022-01-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1159501-2
    ISSN 1536-3732 ; 1049-2275
    ISSN (online) 1536-3732
    ISSN 1049-2275
    DOI 10.1097/SCS.0000000000008456
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Complication Rates From Otoplasty at a Tertiary Facial Plastic Surgery Center: A Retrospective Analysis.

    AlAwadh, Ibrahim / Alassiry, Hassan / Bogari, Ahmad / Alabduljabbar, Ziyad / AlDosari, Badi

    The Journal of craniofacial surgery

    2022  Volume 33, Issue 6, Page(s) 1813–1815

    Abstract: Abstract: Prominent ears are considered the most common congenital external ear deformity among Caucasians. Affecting approximately 5% of the population, it runs in families and exhibits equal sex incidence. This study aimed to determine the ... ...

    Abstract Abstract: Prominent ears are considered the most common congenital external ear deformity among Caucasians. Affecting approximately 5% of the population, it runs in families and exhibits equal sex incidence. This study aimed to determine the complication rate from otoplasty in a tertiary facial plastic surgery center. This retrospective cross-sectional study included all patients with prominent ears deformities who underwent otoplasty at King Abdul-Aziz University Hospital between January 2019 and June 2021. The records of 116 patients who underwent otoplasty during the study period were examined and only 44 matched the inclusion and exclusion criteria. The total of 85 operated ears from 44 patients were included. Of these, 17 were pediatric patients and 25 were male patients. Forty-one patients underwent bilateral otoplasty and 3 underwent unilateral otoplasty. Complications occurred in 17/85 (20%) patients and the complications included recurrence 4 (4.70%), hypertrophic scar 3 (3.52%), keloid 2 (2.35), granuloma 2 (2.35%), infection 2 (2.35%), discomfort 1 (1.17%), wound dehiscence 1 (1.17%), hematoma 1 (1.17%), and retracted ear 1 (1.17%). The overall patient satisfaction was 38/44 (86.36%). Our study is first study conducted in middle east about otoplasty complications. It showed that the complications from otoplasty surgery varied from severe to mild, with acceptable overall satisfactory results. The most common complication was recurrence. Fortunately, serious complications, such as wound dehiscence and hematoma, were rare. However, our study's small sample size remains a major limitation.
    MeSH term(s) Child ; Cross-Sectional Studies ; Ear, External/abnormalities ; Ear, External/surgery ; Female ; Hematoma/surgery ; Humans ; Male ; Postoperative Complications/epidemiology ; Postoperative Complications/surgery ; Reconstructive Surgical Procedures/adverse effects ; Reconstructive Surgical Procedures/methods ; Retrospective Studies ; Surgery, Plastic
    Language English
    Publishing date 2022-01-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1159501-2
    ISSN 1536-3732 ; 1049-2275
    ISSN (online) 1536-3732
    ISSN 1049-2275
    DOI 10.1097/SCS.0000000000008455
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Integrated traditional herbal medicine in the treatment of gastrointestinal disorder: the pattern of use and the knowledge of safety among the Eastern Region Saudi population.

    Elmaghraby, Dalia Ahmed / Alsalman, Ghufran Adnan / Alawadh, Layla Hassan / Al-Abdulqader, Sara Abdulaziz / Alaithan, Malak Mohammed / Alnuwaysir, Bayan Ibrahim

    BMC complementary medicine and therapies

    2023  Volume 23, Issue 1, Page(s) 373

    Abstract: Background: Herbal medicine is commonly integrated with conventional medicine in Saudi Arabia, especially for the management of digestive disorders. However, the majority of Saudis use herbal remedies without prior consultation with a physician, which ... ...

    Abstract Background: Herbal medicine is commonly integrated with conventional medicine in Saudi Arabia, especially for the management of digestive disorders. However, the majority of Saudis use herbal remedies without prior consultation with a physician, which raises concerns about their appropriate and safe use. The aim of this study was to assess the level of awareness among the Saudi population regarding the proper utilization and potential adverse effects of frequently used herbs for the treatment of gastrointestinal (GI) diseases.
    Methods: A cross-sectional survey was conducted in Saudi Arabia from January to March 2021. An electronic self-administered questionnaire was distributed.
    Results: A total of 543 participants from different age groups, educational levels, and cities across Saudi Arabia completed the study questionnaire. The most commonly used herbs at home by the participants were: myrrh, parsley, black seed, chamomile, mint, anise, clove, and green tea. 57.7% of the participants perceived herbs as safer than conventional medicines; 27.3% reported that using herbal remedies over conventional medicine was a family tradition, and 21.4% used herbs because they were cheaper than conventional medicines.
    Conclusion: Herbal remedies, including myrrh, parsley, blackseed, chamomile, mint, and anise, are commonly employed for the treatment of gastrointestinal disorders in Saudi Arabia. However, the knowledge level of participants regarding potential side effects and drug-herb interactions was found to be deficient. As such, there is a pressing need for educational campaigns and community awareness programs to elucidate the proper usage of herbal remedies and to caution against their potential adverse effects.
    MeSH term(s) Humans ; Saudi Arabia ; Cross-Sectional Studies ; Health Knowledge, Attitudes, Practice ; Herbal Medicine ; Plants, Medicinal ; Gastrointestinal Diseases/drug therapy
    Language English
    Publishing date 2023-10-23
    Publishing country England
    Document type Journal Article
    ISSN 2662-7671
    ISSN (online) 2662-7671
    DOI 10.1186/s12906-023-04197-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Integrated traditional herbal medicine in the treatment of gastrointestinal disorder

    Dalia Ahmed Elmaghraby / Ghufran Adnan Alsalman / Layla Hassan Alawadh / Sara Abdulaziz Al-Abdulqader / Malak Mohammed Alaithan / Bayan Ibrahim Alnuwaysir

    BMC Complementary Medicine and Therapies, Vol 23, Iss 1, Pp 1-

    the pattern of use and the knowledge of safety among the Eastern Region Saudi population

    2023  Volume 12

    Abstract: Abstract Background Herbal medicine is commonly integrated with conventional medicine in Saudi Arabia, especially for the management of digestive disorders. However, the majority of Saudis use herbal remedies without prior consultation with a physician, ... ...

    Abstract Abstract Background Herbal medicine is commonly integrated with conventional medicine in Saudi Arabia, especially for the management of digestive disorders. However, the majority of Saudis use herbal remedies without prior consultation with a physician, which raises concerns about their appropriate and safe use. The aim of this study was to assess the level of awareness among the Saudi population regarding the proper utilization and potential adverse effects of frequently used herbs for the treatment of gastrointestinal (GI) diseases. Methods A cross-sectional survey was conducted in Saudi Arabia from January to March 2021. An electronic self-administered questionnaire was distributed. Results A total of 543 participants from different age groups, educational levels, and cities across Saudi Arabia completed the study questionnaire. The most commonly used herbs at home by the participants were: myrrh, parsley, black seed, chamomile, mint, anise, clove, and green tea. 57.7% of the participants perceived herbs as safer than conventional medicines; 27.3% reported that using herbal remedies over conventional medicine was a family tradition, and 21.4% used herbs because they were cheaper than conventional medicines. Conclusion Herbal remedies, including myrrh, parsley, blackseed, chamomile, mint, and anise, are commonly employed for the treatment of gastrointestinal disorders in Saudi Arabia. However, the knowledge level of participants regarding potential side effects and drug-herb interactions was found to be deficient. As such, there is a pressing need for educational campaigns and community awareness programs to elucidate the proper usage of herbal remedies and to caution against their potential adverse effects.
    Keywords Phytomedicine ; Gastrointestinal ; Complementary therapies ; Health behaviors ; Herb-drug interactions ; Plant preparations ; Other systems of medicine ; RZ201-999
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: A Novel Technique for Spreader Flap by Folding the Dorsal Hump in Patients Undergoing Primary Rhinoplasty.

    AlAwadh, Ibrahim H / Bogari, Ahmad / Assiri, Hassan / Alabduljabbar, Ziyad / AlNassar, Raad / Hudise, Jibril / AlArfaj, Ahmed

    The Journal of craniofacial surgery

    2022  Volume 33, Issue 8, Page(s) 2653–2658

    Abstract: Objectives: We describe our novel modified spreader flap, which involves keeping the large cartilaginous septal T hump attached to the upper lateral cartilages to increase the thickness and length of the flap. Our objectives were to assess hump ... ...

    Abstract Objectives: We describe our novel modified spreader flap, which involves keeping the large cartilaginous septal T hump attached to the upper lateral cartilages to increase the thickness and length of the flap. Our objectives were to assess hump reduction and recurrence, nasal axis deviation, dorsal width, internal nasal valve grade, and Rhinoplasty Outcome Evaluation (ROE) score preoperatively and one year postoperatively.
    Materials and methods: In a prospective study that included 21 patients who met the criteria, patients were followed up for 1 year after surgery, with an assessment of the dorsal projection, tip projection, axis deviation, dorsal width, and internal nasal valve grade. In addition, the modified Cottle maneuver and Rhinoplasty Outcome Evaluation score were also performed and obtained, respectively.
    Results: Our novel technique was performed in 20 patients (95.2%). In 1 additional patient, we added a regular auto-spreader flap on the contralateral side. One year postoperatively, the axis was found in the midline in all patients (100%). Assessment of internal valve collapse showed that collapse was reduced to grade 0 in 13 patients (61.9%) and grade 1 in 8 patients (38.1%). There were no hump recurrences or visible irregularities. The results showed a statistically significant difference between the pre- and postoperative values in dorsal projection, dorsal width, and rhinoplasty outcome evaluation score.
    Conclusions: This novel technique shows promising statistically significant results in reducing dorsal hump projection and width, correcting axis deviation, and improving internal nasal valve and rhinoplasty outcome evaluation score, while being less cartilage and time-consuming.
    MeSH term(s) Humans ; Rhinoplasty/methods ; Nasal Cartilages/surgery ; Nasal Septum/surgery ; Prospective Studies ; Surgical Flaps/surgery
    Language English
    Publishing date 2022-08-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1159501-2
    ISSN 1536-3732 ; 1049-2275
    ISSN (online) 1536-3732
    ISSN 1049-2275
    DOI 10.1097/SCS.0000000000008847
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The Effect of Selfies on Cosmetic Surgery

    Mohammed ALKARZAE / Badi ALDOSARI / Lama ALALULA / Reham ALMUHAYA / İbrahim ALAWADH

    ENT Updates, Vol 10, Iss 1, Pp 251-

    2020  Volume 260

    Keywords Medicine ; R ; Otorhinolaryngology ; RF1-547
    Language English
    Publishing date 2020-04-01T00:00:00Z
    Publisher Continuing Education and Scientific Research Association (CESRA), Turkey
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Prevalence of Body Dysmorphic Disorder Among Rhinoplasty Candidates: A Systematic Review.

    AlAwadh, Ibrahim / Bogari, Ahmad / Azhar, Turki / AlTaylouni, Nada / AlSughier, Naif / AlKarzae, Mohammed / AlQuniabut, Ibrahim / AlDosari, Badi

    Ear, nose, & throat journal

    2021  , Page(s) 1455613211056543

    Abstract: Objective: Body dysmorphic disorder (BDD) represents a bridge between the fields of psychiatry and cosmetic surgery. It is a psychiatric disorder involving altered body image and has been associated with cosmetic surgery. Many studies have investigated ... ...

    Abstract Objective: Body dysmorphic disorder (BDD) represents a bridge between the fields of psychiatry and cosmetic surgery. It is a psychiatric disorder involving altered body image and has been associated with cosmetic surgery. Many studies have investigated BDD following rhinoplasty. However, their findings were inconsistent, which prompted us to conduct this systematic review to obtain strong evidence about the prevalence of BDD among rhinoplasty candidates.
    Methods: We searched the literature using electronic databases such as PubMed, Scopus, Web of Science, and others using keywords relevant to the study outcomes. We also manually examined the references of the included studies and relevant reviews to look for articles that might have been missed during the electronic search.
    Results: Nine articles met the inclusion criteria. We identified 7 other relevant articles; since they had been included in a review conducted in 2016, they were not included in the final list of articles. However, they were included in the discussion, and their findings have been compared with ours. The included articles resulted in a total sample of 712 rhinoplasty candidates. The estimated prevalence rates of BDD in these articles ranged from 22% to 52%, which was considered high by all the authors of the included studies.
    Conclusion: The prevalence of BDD among rhinoplasty candidates is high, and adequate management and interventions are needed to reduce it.
    Language English
    Publishing date 2021-11-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 750153-5
    ISSN 1942-7522 ; 0145-5613
    ISSN (online) 1942-7522
    ISSN 0145-5613
    DOI 10.1177/01455613211056543
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Design, synthesis and anticancer activity of novel valproic acid conjugates with improved histone deacetylase (HDAC) inhibitory activity.

    Ibrahim, Tarek S / Sheha, Taghreed A / Abo-Dya, Nader E / AlAwadh, Mohammed A / Alhakamy, Nabil A / Abdel-Samii, Zakaria K / Panda, Siva S / Abuo-Rahma, Gamal El-Din A / Mohamed, Mamdouh F A

    Bioorganic chemistry

    2020  Volume 99, Page(s) 103797

    Abstract: Twenty-five valproic acid conjugates have been designed and synthesized. All target compounds were explored for their in vitro anti-proliferative activities using the MTT-based assay against four human cancer cell lines includingliver (HePG2), colon ( ... ...

    Abstract Twenty-five valproic acid conjugates have been designed and synthesized. All target compounds were explored for their in vitro anti-proliferative activities using the MTT-based assay against four human cancer cell lines includingliver (HePG2), colon (HCT116), breast (MCF7) and cervical (HeLa) carcinoma cell lines. Out of six valproic acid-amino acid conjugates 2a-f. Only cysteine containing conjugate 2f showed the significant activity (IC
    MeSH term(s) Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Drug Design ; Drug Screening Assays, Antitumor ; Histone Deacetylase Inhibitors/chemical synthesis ; Histone Deacetylase Inhibitors/chemistry ; Histone Deacetylase Inhibitors/pharmacology ; Histone Deacetylases/metabolism ; Humans ; Isoenzymes/antagonists & inhibitors ; Isoenzymes/metabolism ; Molecular Docking Simulation ; Molecular Structure ; Structure-Activity Relationship ; Valproic Acid/chemical synthesis ; Valproic Acid/chemistry ; Valproic Acid/pharmacology
    Chemical Substances Antineoplastic Agents ; Histone Deacetylase Inhibitors ; Isoenzymes ; Valproic Acid (614OI1Z5WI) ; Histone Deacetylases (EC 3.5.1.98)
    Language English
    Publishing date 2020-03-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 120080-x
    ISSN 1090-2120 ; 0045-2068
    ISSN (online) 1090-2120
    ISSN 0045-2068
    DOI 10.1016/j.bioorg.2020.103797
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Bilateral peritonsillar abscess: A case report and pertinent literature review.

    AlAwadh, Ibrahim / Aldrees, Turki / AlQaryan, Saleh / Alharethy, Sami / AlShehri, Hassan

    International journal of surgery case reports

    2017  Volume 36, Page(s) 34–37

    Abstract: Introduction: The peritonsillar space is defined as the area between the palatine tonsillar capsule medially and the superior pharyngeal constrictor muscle laterally. Unilateral peritonsillar abscess (PTA) is more common than the bilateral condition. To ...

    Abstract Introduction: The peritonsillar space is defined as the area between the palatine tonsillar capsule medially and the superior pharyngeal constrictor muscle laterally. Unilateral peritonsillar abscess (PTA) is more common than the bilateral condition. To the best of our knowledge, only 13 cases of bilateral PTA have been reported worldwide; this is the first case reported from Saudi Arabia.
    Presentation of case: We present a case involving a 16-year-old boy who presented to the emergency department with a5-day history of sore throat, dysphagia, trismus, drooling, and a muffled "hot-potato" voice, but with no symptoms of airway compromise. After several examinations, we diagnosed bilateral PTA. We performed an incision and drained the pus from both sides, which was positive for Streptococcus pyogenes. Postoperatively, the patient improved dramatically, and tonsillectomy was scheduled for 6 weeks later.
    Discussion: The difficulty in diagnosing bilateral PTA stems from the fact that it does not present with the usual clinical characteristics as unilateral PTA. These symptoms include asymmetry of the tonsils and palate, deviation of the uvula, and unilateral otalgia. As these cases carry the risk of impending airway compromise, we recommend airway management as the first step in treating such cases.
    Conclusion: Based on our case and literature review, we recommend airway management as the first step, followed by further examinations, especially contrast-enhanced computed tomography, in cases of bilateral PTA. This condition lacks the hallmark of unilateral disease and may mimic many conditions, which will have different management approaches.
    Language English
    Publishing date 2017-05-15
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2210-2612
    ISSN 2210-2612
    DOI 10.1016/j.ijscr.2017.04.028
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: The serious complications of frontal sinusitis, a case series and literature review.

    Al Yaeesh, Ibrahim / AlOmairin, Ahmed / Al Shakhs, Abdullah / Almomen, Ali / Almomen, Zahra / AlBahr, Abdulelah / AlNaim, Abdulrahman / Al Abdulgader, Abdulrahman / Alawadh, Abdullah

    Journal of surgical case reports

    2020  Volume 2020, Issue 12, Page(s) rjaa474

    Abstract: The aim of this study is to illustrate the managements of different clinical and radiological presentations of serious complications of frontal sinusitis diagnosed and managed at the tertiary referral hospital. A case series study conducted at the ... ...

    Abstract The aim of this study is to illustrate the managements of different clinical and radiological presentations of serious complications of frontal sinusitis diagnosed and managed at the tertiary referral hospital. A case series study conducted at the tertiary referral in the period from 2012 to 2019. Four different cases of serious complications of frontal sinusitis namely orbital abscess, frontal meningitis, subdural empyema and frontal lobe abscess will be presented and discussed. Despite the generous use of antibiotics, the serious complications of frontal sinusitis still develop. The serious complications of frontal sinusitis ranges from orbital abscess to frank frontal lobe abscess. The management is a combination of systemic antibiotics and surgical drainage with excellent outcomes.
    Language English
    Publishing date 2020-12-31
    Publishing country England
    Document type Case Reports
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/rjaa474
    Database MEDical Literature Analysis and Retrieval System OnLINE

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