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Article ; Online: The impact of body compositions on contrast medium enhancement in chest CT: a randomised controlled trial.

Henning, Mette Karen / Aaløkken, Trond Mogens / Martinsen, Anne Catrine / Johansen, Safora

BJR open

2023 Volume 5, Issue 1, Page(s) 20230054

Abstract: Objective: To compare a fixed-volume contrast medium (CM) protocol with a combined total body weight (TBW) and body composition-tailored protocol in chest CT.: Methods and materials: Patients referred for routine contrast enhanced chest CT were ... ...

Abstract	Objective: To compare a fixed-volume contrast medium (CM) protocol with a combined total body weight (TBW) and body composition-tailored protocol in chest CT. Methods and materials: Patients referred for routine contrast enhanced chest CT were prospectively categorised as normal, muscular or overweight. Patients were accordingly randomised into two groups; Group 1 received a fixed CM protocol. Group 2 received CM volume according to a body composition-tailored protocol. Objective image quality comparisons between protocols and body compositions were performed. Differences between groups and correlation were analysed using Results: A total of 179 patients were included: 87 in Group 1 (mean age, 51 ± 17 years); and 92 in Group 2 (mean age, 52 ± 17 years). Compared to Group 2, Group 1 showed lower vascular attenuation in muscular (mean 346 Hounsfield unit (HU) Conclusion: A combined TBW and body composition-tailored CM protocol in chest CT resulted in more homogenous enhancement and fewer outliers compared to a fixed-volume protocol. Advances in knowledge: This is, to our knowledge, the first study to investigate the impact of various body compositions on contrast medium enhancement in chest CT.
Language	English
Publishing date	2023-10-18
Publishing country	England
Document type	Journal Article
ISSN	2513-9878
ISSN (online)	2513-9878
DOI	10.1259/bjro.20230054
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Article ; Online: Treatment of a pneumatocele in a COVID-19 patient with endobronchial valves.

Bugge, Anders Standal / Sundset, Arve / Aaløkken, Trond Mogens / Jørgensen, Lars Hilmar

BMJ case reports

2022 Volume 15, Issue 6

Abstract: A man in his 40s was admitted to his local hospital 6 days after the first vague symptoms of COVID-19. His general condition deteriorated, and he was treated in the intensive care unit but did not require mechanical ventilation. During his recovery, he ... ...

Abstract	A man in his 40s was admitted to his local hospital 6 days after the first vague symptoms of COVID-19. His general condition deteriorated, and he was treated in the intensive care unit but did not require mechanical ventilation. During his recovery, he experienced a cough spell, after which his dyspnoea recurred and rapidly increased. CT pulmonary angiogram showed a 10×18 cm cavitary lesion with an air-fluid level and surrounding atelectasis of the right lower lobe. A one-way valve mechanism had developed, leading to the formation of a pneumatocele. The patient was treated by occlusion of all bronchial segments of the right lower lobe with endobronchial valves, and the pneumatocele was evacuated with a pigtail catheter. The valves were removed 4 weeks after insertion, and the right lower lobe re-expanded. Six months after treatment, the patient had recovered completely and almost regained his former lung function.
MeSH term(s)	Bronchi ; COVID-19 ; Cysts ; Humans ; Male ; Neoplasm Recurrence, Local ; Prostheses and Implants
Language	English
Publishing date	2022-06-21
Publishing country	England
Document type	Case Reports ; Journal Article
ISSN	1757-790X
ISSN (online)	1757-790X
DOI	10.1136/bcr-2022-250409
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Article ; Online: Intraoperative computed tomography during fenestrated and branched endovascular aortic repair: a feasibility study.

Schrøder-Aasen, Anne Marte / Carling, Ulrik / Aaløkken, Trond Mogens / Rasmussen, Margrethe Kallestad / Dorenberg, Eric

Acta radiologica (Stockholm, Sweden : 1987)

2023 Volume 64, Issue 6, Page(s) 2205–2210

Abstract: Background: Endovascular aortic repair with fenestrated or branched endografts is technically challenging, and proper intraoperative assessment of all stent graft components with only angiography and fluoroscopy can be difficult. Intraoperative computed ...

Abstract	Background: Endovascular aortic repair with fenestrated or branched endografts is technically challenging, and proper intraoperative assessment of all stent graft components with only angiography and fluoroscopy can be difficult. Intraoperative computed tomography (CT) imaging can be a valuable aid for the operators in the evaluation of stent grafting results prior to completion of surgery. Purpose: To examine the feasibility of performing intraoperative CT imaging during fenestrated and branched endovascular aortic repair (f-bEVAR) under sterile conditions and with patients under general anesthesia. Material and methods: Intraoperative CT imaging was performed in 10 patients undergoing elective aortic repair with fenestrated or branched endografts. Adverse events, time consumption for CT set-up and image acquisition, and additional radiation dose to the patient were recorded. CT image quality was graded. Immediate corrective maneuvers performed based on the CT findings was registered. Results: There were no adverse events related to intraoperative CT imaging. The median additional operating time by including intraoperative CT was 16 min (interquartile range [IQR] = 12-19), comprising 7% of the median total operating time. The median estimated additional radiation dose to the patient was 4.8 mSv (IQR = 3.8-4.9). All intraoperative CT examinations were considered to be of sufficient quality for stent graft evaluation. No immediate corrective procedures were performed on the basis of CT findings in this study cohort. Conclusion: CT imaging intraoperatively during f-bEVAR is feasible with an acceptable increase in operating time and radiation dose.
MeSH term(s)	Humans ; Blood Vessel Prosthesis ; Aortic Aneurysm, Thoracic/etiology ; Aortic Aneurysm, Thoracic/surgery ; Blood Vessel Prosthesis Implantation ; Feasibility Studies ; Endovascular Aneurysm Repair ; Aortography/methods ; Treatment Outcome ; Endovascular Procedures/methods ; Time Factors ; Tomography, X-Ray Computed ; Retrospective Studies ; Risk Factors
Language	English
Publishing date	2023-04-28
Publishing country	England
Document type	Journal Article
ZDB-ID	105-3
ISSN	1600-0455 ; 0284-1851 ; 0349-652X
ISSN (online)	1600-0455
ISSN	0284-1851 ; 0349-652X
DOI	10.1177/02841851231165673
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Article ; Online: Contrast medium protocols in routine chest CT: a survey study.

Henning, Mette Karen / Aaløkken, Trond Mogens / Johansen, Safora

Acta radiologica (Stockholm, Sweden : 1987)

2021 Volume 63, Issue 3, Page(s) 351–359

Abstract: Background: Administration of contrast medium (CM) is an important image quality factor in computed tomography (CT) of the chest. There is no clear evidence or guidelines on CM strategies for chest CT, thus a consensus approach is needed.: Purpose: ... ...

Abstract	Background: Administration of contrast medium (CM) is an important image quality factor in computed tomography (CT) of the chest. There is no clear evidence or guidelines on CM strategies for chest CT, thus a consensus approach is needed. Purpose: To survey the potential impact on differences in chest CT protocols, with emphasis on strategies for the administration of CM. Material and methods: A total of 170 respondents were included in this survey, which used two different approaches: (i) an online survey was sent to the members of the European Society of Thoracic Imaging (ESTI); and (ii) an email requesting a copy of their CT protocol was sent to all hospitals in Norway, and university hospitals in Sweden and Denmark. The survey focused on factors affecting CM protocols and enhancement in chest CT. Results: The overall response rate was 24% (n = 170): 76% of the respondents used a CM concentration of ≥350 mgI/mL; 52% of the respondents used a fixed CM volume strategy. Fixed strategies for injection rate and delay were also the most common approach, practiced by 73% and 57% of the respondents, respectively. The fixed delay was in the range of 20-90 s. Of the respondents, 56% used flexible tube potential strategies (kV). Conclusion: The chest CT protocols and CM administration strategies employed by the respondents vary widely, affecting the image quality. The results of this study underline the need for further research and consensus guidelines related to chest CT.
MeSH term(s)	Contrast Media/administration & dosage ; Denmark ; Europe ; Health Care Surveys/methods ; Health Care Surveys/statistics & numerical data ; Humans ; Norway ; Radiographic Image Enhancement ; Radiography, Thoracic ; Societies, Medical/statistics & numerical data ; Sweden ; Time Factors ; Tomography, X-Ray Computed
Chemical Substances	Contrast Media
Language	English
Publishing date	2021-03-01
Publishing country	England
Document type	Journal Article
ZDB-ID	105-3
ISSN	1600-0455 ; 0284-1851 ; 0349-652X
ISSN (online)	1600-0455
ISSN	0284-1851 ; 0349-652X
DOI	10.1177/0284185121997111
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Article ; Online: The radiation exposure controversy.

Aaløkken, Trond Mogens

Acta radiologica (Stockholm, Sweden : 1987)

2011 Volume 52, Issue 7, Page(s) 699

MeSH term(s)	Humans ; Neoplasms, Radiation-Induced/etiology ; Radiation Dosage ; Tomography, X-Ray Computed/adverse effects
Language	English
Publishing date	2011-09-01
Publishing country	England
Document type	Comment ; Editorial
ZDB-ID	105-3
ISSN	1600-0455 ; 0284-1851 ; 0349-652X
ISSN (online)	1600-0455
ISSN	0284-1851 ; 0349-652X
DOI	10.1258/ar.2011.11a008
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Article: A prospective study of pulmonary outcomes and chest computed tomography in the first year after COVID-19.

Lerum, Tøri Vigeland / Meltzer, Carin / Rodriguez, Jezabel Riverio / Aaløkken, Trond Mogens / Brønstad, Eivind / Aarli, Bernt B / Aarberg-Lund, Kristine Marie / Durheim, Michael T / Ashraf, Haseem / Einvik, Gunnar / Skjønsberg, Ole Henning / Stavem, Knut

ERJ open research

2023 Volume 9, Issue 2

Abstract: COVID-19 primarily affects the respiratory system. We aimed to evaluate how pulmonary outcomes develop after COVID-19 by assessing participants from the first pandemic wave prospectively 3 and 12 months following hospital discharge. Pulmonary outcomes ... ...

Abstract	COVID-19 primarily affects the respiratory system. We aimed to evaluate how pulmonary outcomes develop after COVID-19 by assessing participants from the first pandemic wave prospectively 3 and 12 months following hospital discharge. Pulmonary outcomes included self-reported dyspnoea assessed with the modified Medical Research Council dyspnoea scale, 6-min walk distance (6MWD), spirometry, diffusing capacity of the lung for carbon monoxide (
Language	English
Publishing date	2023-03-13
Publishing country	England
Document type	Journal Article
ZDB-ID	2827830-6
ISSN	2312-0541
ISSN	2312-0541
DOI	10.1183/23120541.00575-2022
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Article ; Online: Suture material in the respiratory tract.

Myrdal, Ole H / Sundset, Arve / Aaløkken, Trond Mogens / Hjalmarsen, Audhild

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke

2019 Volume 139, Issue 11

Title translation	Suturtråd i luftveiene.
MeSH term(s)	Bronchi/diagnostic imaging ; Bronchi/pathology ; Bronchoscopy ; Female ; Foreign Bodies/diagnostic imaging ; Foreign Bodies/pathology ; Humans ; Middle Aged ; Sutures ; Tomography, X-Ray Computed
Language	Norwegian
Publishing date	2019-08-08
Publishing country	Norway
Document type	Case Reports
ZDB-ID	603504-8
ISSN	0807-7096 ; 0029-2001
ISSN (online)	0807-7096
ISSN	0029-2001
DOI	10.4045/tidsskr.19.0089
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Zs.MO 546: Show issues

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Article ; Online: Associations between cardiac and pulmonary involvement in patients with juvenile dermatomyositis-a cross-sectional study.

Witczak, Birgit Nomeland / Schwartz, Thomas / Barth, Zoltan / Taraldsrud, Eli / Lund, May Brit / Aaløkken, Trond Mogens / Flatø, Berit / Sjaastad, Ivar / Sanner, Helga

Rheumatology international

2022 Volume 42, Issue 7, Page(s) 1213–1220

Abstract: This study aimed at exploring the association between detectable cardiac and pulmonary involvement in long-term juvenile dermatomyositis (JDM) and to assess if patients with cardiac and pulmonary involvement differ with regard to clinical characteristics. ...

Abstract	This study aimed at exploring the association between detectable cardiac and pulmonary involvement in long-term juvenile dermatomyositis (JDM) and to assess if patients with cardiac and pulmonary involvement differ with regard to clinical characteristics. 57 JDM patients were examined mean 17.3 (10.5) years after disease onset; this included clinical examination, myositis specific/associated autoantibodies (immunoblot), echocardiography, pulmonary function tests and high-resolution computed tomography. Cardiac involvement was defined as diastolic and/or systolic left ventricular dysfunction and pulmonary involvement as low diffusing capacity for carbon monoxide, low total lung capacity and/or high-resolution computed tomography abnormalities. Patients were stratified into the following four groups: (i) no organ involvement, (ii) pulmonary only, (iii) cardiac only, and (iv) co-existing pulmonary and cardiac involvement. Mean age was 25.7 (12.4) years and 37% were males. One patient had coronary artery disease, seven had a history of pericarditis, seven had hypertension and three had known interstitial lung disease prior to follow-up. There was no association between cardiac (10/57;18%) and pulmonary (41/57;72%) involvement (p = 0.83). After stratifying by organ involvement, 21% of patients had no organ involvement; 61% had pulmonary involvement only; 7% had cardiac involvement only and 11% had co-existing pulmonary or cardiac involvement. Patients with co-existing pulmonary or cardiac involvement had higher disease burden than the remaining patients. Patients with either cardiac or pulmonary involvement only, differed in clinical and autoantibody characteristics. We found no increased risk of developing concomitant cardiac/pulmonary involvement in JDM. Our results shed light upon possible different underlying mechanisms behind pulmonary and cardiac involvement in JDM.
MeSH term(s)	Adult ; Autoantibodies ; Cross-Sectional Studies ; Dermatomyositis/complications ; Female ; Heart ; Humans ; Lung Diseases, Interstitial/etiology ; Male ; Respiratory Function Tests/adverse effects
Chemical Substances	Autoantibodies
Language	English
Publishing date	2022-01-04
Publishing country	Germany
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	8286-7
ISSN	1437-160X ; 0172-8172
ISSN (online)	1437-160X
ISSN	0172-8172
DOI	10.1007/s00296-021-05071-3
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Article ; Online: Image Quality Measured From Ultra-Low Dose Chest Computed Tomography Examination Protocols Using 6 Different Iterative Reconstructions From 4 Vendors, a Phantom Study.

Afadzi, Mercy / Fosså, Kristian / Andersen, Hilde Kjernlie / Aaløkken, Trond Mogens / Martinsen, Anne Catrine T

Journal of computer assisted tomography

2020 Volume 44, Issue 1, Page(s) 95–101

Abstract: Purpose: This study aimed to evaluate image quality of ultra-low dose chest computed tomography using 6 iterative reconstruction (IR) algorithms.: Method: A lung phantom was scanned on 4 computed tomography scanners using fixed tube voltages and the ... ...

Abstract	Purpose: This study aimed to evaluate image quality of ultra-low dose chest computed tomography using 6 iterative reconstruction (IR) algorithms. Method: A lung phantom was scanned on 4 computed tomography scanners using fixed tube voltages and the lowest mAs available on each scanner, resulting in dose levels of 0.1 to 0.2 mGy (80 kVp) and 0.3 to 1 mGy (140 kVp) volume CT dose index (CTDIvol). Images were reconstructed with IR available on the scanners. Image noise, signal-to-noise ratios, contrast-to-noise ratios, uniformity, and noise power spectrum (NPS) were assessed for evaluation of image quality. Results: Image quality parameters increased with increasing dose for all algorithms. At constant dose levels, model-based techniques improved the contrast-to-noise ratio of lesions more than the statistical algorithms. All algorithms tested at 0.1 mGy showed lower NPS peak frequencies compared with 0.39 mGy. In contrast to the statistical techniques, model-based algorithms showed lower NPS peak frequencies at the lowest doses, indicating a coarser and blotchier noise texture. Conclusion: This study shows the importance of evaluating IR when introduced clinically.
MeSH term(s)	Algorithms ; Contrast Media ; Humans ; Lung/diagnostic imaging ; Phantoms, Imaging ; Radiation Dosage ; Radiographic Image Interpretation, Computer-Assisted/methods ; Signal-To-Noise Ratio ; Tomography, X-Ray Computed/instrumentation
Chemical Substances	Contrast Media
Language	English
Publishing date	2020-01-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	80392-3
ISSN	1532-3145 ; 0363-8715
ISSN (online)	1532-3145
ISSN	0363-8715
DOI	10.1097/RCT.0000000000000947
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Article ; Online: Response to "usefulness of diffusion-weighted magnetic resonance imaging for assessing early treatment response in lymphoma patients".

Hagtvedt, Trond / Smith, Hans-Jørgen / Aaløkken, Trond Mogens

Acta radiologica (Stockholm, Sweden : 1987)

2015 Volume 56, Issue 2, Page(s) NP12–3

MeSH term(s)	Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Bleomycin/administration & dosage ; Dacarbazine/administration & dosage ; Diffusion Magnetic Resonance Imaging/methods ; Doxorubicin/administration & dosage ; Female ; Head and Neck Neoplasms/diagnosis ; Head and Neck Neoplasms/drug therapy ; Humans ; Lymphoma/diagnosis ; Lymphoma/drug therapy ; Male ; Tomography, X-Ray Computed/methods ; Vinblastine/administration & dosage
Chemical Substances	Bleomycin (11056-06-7) ; Vinblastine (5V9KLZ54CY) ; Dacarbazine (7GR28W0FJI) ; Doxorubicin (80168379AG)
Language	English
Publishing date	2015-02
Publishing country	England
Document type	Comment ; Letter
ZDB-ID	105-3
ISSN	1600-0455 ; 0284-1851 ; 0349-652X
ISSN (online)	1600-0455
ISSN	0284-1851 ; 0349-652X
DOI	10.1177/0284185114554355
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