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  1. Book: Toxikologie für Einsteiger

    Barth, Holger / Ernst, Katharina / Papatheodorou, Panagiotis

    2023  

    Author's details Holger Barth, Katharina Ernst, Panagiotis Papatheodorou
    Keywords Giftnotruf ; Antidot ; Pestizide ; Pharmakologie ; Karzenogenese ; Rezeptor ; Vergiftung ; Gift ; Toxikokinetik ; Dosis ; Pflanzengift ; Toxikologie
    Subject Giftkunde ; Klinische Toxikologie
    Language German
    Size IX, 137 Seiten, Illustrationen, 24 cm x 16.8 cm
    Publisher Springer Spektrum
    Publishing place Berlin
    Publishing country Germany
    Document type Book
    HBZ-ID HT021739633
    ISBN 978-3-662-61539-3 ; 9783662615409 ; 3-662-61539-8 ; 3662615401
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2023 A 411 available for loan (reading room) Lesesaal EG

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  2. Book: Uptake and trafficking of protein toxins

    Barth, Holger

    (Current topics in microbiology and immunology ; volume 406 ; Biomedicine)

    2017  

    Author's details Holger Barth, editor
    Series title Current topics in microbiology and immunology ; volume 406
    Biomedicine
    Collection
    Language English
    Size vii, 256 Seiten, Illustrationen, Diagramme
    Publisher Springer
    Publishing place Cham, Switzerland
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT019553566
    ISBN 978-3-319-58891-9 ; 9783319588933 ; 3-319-58891-5 ; 3319588931
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Ud II Zs 24 -406- verfügbar in Königswinter Königswinter

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  3. Book ; Online ; E-Book: Uptake and trafficking of protein toxins

    Barth, Holger

    (Current topics in microbiology and immunology ; 406)

    2017  

    Author's details Holger Barth editor
    Series title Current topics in microbiology and immunology ; 406
    Collection
    Keywords Bacterial Toxins ; Bacterial Proteins ; Cell Membrane / metabolism ; Vesicular Transport Proteins ; Medicine ; Medical microbiology ; Pharmacology ; Infectious diseases
    Subject code 616.9041
    Language English
    Size 1 Online-Ressource (vii, 256 Seiten), Illustrationen, Diagramme
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019701555
    ISBN 978-3-319-58893-3 ; 9783319588919 ; 3-319-58893-1 ; 3319588915
    DOI 10.1007/978-3-319-58893-3
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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  4. Book ; Online: Novel Pharmacological Inhibitors for Bacterial Protein Toxins

    Barth, Holger

    2017  

    Abstract: Many medically relevant bacteria cause severe human and animal diseases because they produce and release protein toxins that target mammalian cells. Because the toxin-induced cell damage is the reason for the clinical symptoms, the targeted ... ...

    Abstract Many medically relevant bacteria cause severe human and animal diseases because they produce and release protein toxins that target mammalian cells. Because the toxin-induced cell damage is the reason for the clinical symptoms, the targeted pharmacological inhibition of the cytotoxic mode of action of bacterial toxins should prevent or cure the respective toxin-associated disease. Toxin inhibitors might be beneficial when the toxin acts in the absence of the producing bacteria (e.g., food poisoning), but also in combination with antibiotics in infectious diseases when the toxin-producing bacteria are present. The focus of this Special Issue of Toxins is on the development and characterization of novel inhibitors against bacterial toxins, e.g., toxin neutralizing antibodies, peptides or small compounds, as well as toxin pore blockers, which interfere with bacterial toxins and thereby protect cells from intoxication
    Keywords Toxicology. Poisons ; Biology (General)
    Size 1 electronic resource (VI, 118 p.)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020094482
    ISBN 9783038424314 ; 9783038424307 ; 3038424315 ; 3038424307
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Book: Toxikologie

    Marquardt, Hans / Schäfer, Siegfried G. / Barth, Holger

    2019  

    Author's details Marquardt/Schäfer/Barth (Hrsg.)
    Keywords Toxikologie
    Subject Giftkunde ; Klinische Toxikologie
    Language German
    Size XXXVIII, 1458 Seiten, Illustrationen, 27 cm x 19.3 cm
    Edition 4., völlig neu bearbeitete Auflage
    Publisher Wissenschaftliche Verlagsgesellschaft
    Publishing place Stuttgart
    Publishing country Germany
    Document type Book
    HBZ-ID HT020082996
    ISBN 978-3-8047-3657-3 ; 3-8047-3657-2 ; 9783804739932 ; 3804739938
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2019 A 1074 available for loan (reading room) Lesesaal EG

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  6. Book: Lebensmittelassoziierte Mikroorganismen Bakterielle Toxine

    Weiß, Agnes / Barth, Holger / Schmidt, Herbert

    Molekulare Struktur, Funktionsweise und Nachweissysteme

    (Lebensmittelassoziierte Mikroorganismen)

    2018  

    Author's details A. Weiß/H. Barth/H. Schmidt
    Series title Lebensmittelassoziierte Mikroorganismen
    Keywords Bakteriengift ; Molekülstruktur ; Wirkungsmechanismus ; Nachweis
    Subject Test ; Nachweisverfahren ; Nachweismethode ; Molekülbau ; Molekularstruktur ; Molekülgeometrie ; Molekulare Geometrie ; Bakterientoxin ; Bakterielles Toxin
    Language German
    Size X, 80 Seiten, Illustrationen, 21 cm x 14.8 cm, 158 g
    Edition 1. Auflage
    Publisher Behr's Verlag
    Publishing place Hamburg
    Publishing country Germany
    Document type Book
    HBZ-ID HT019929869
    ISBN 978-3-95468-616-2 ; 3-95468-616-3
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2019 A 33 available for loan (reading room) Lesesaal EG

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  7. Book ; Online ; E-Book: Toxikologie

    Marquardt, Hans / Schäfer, Siegfried G. / Barth, Holger

    2019  

    Author's details Marquardt / Schäfer / Barth (Hrsg.)
    Keywords Toxikologie
    Subject Giftkunde ; Klinische Toxikologie
    Language German
    Size 1 Online-Ressource (XXXVIII, 1458 Seiten), 513 Illustrationen
    Edition 4., völlig neu bearbeitete Auflage
    Publisher WVG Wissenschaftliche Verlagsgesellschaft
    Publishing place Stuttgart
    Publishing country Germany
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT021182845
    ISBN 978-3-8047-3993-2 ; 9783804736573 ; 3-8047-3993-8 ; 3804736572
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

    Kategorien

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    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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  8. Book: Toxikologie

    Marquardt, Hans / Schäfer, Siegfried G. / Barth, Holger

    mit 378 Tabellen

    2013  

    Author's details hrsg. von Hans Marquardt ; Siegfried G. Schäfer ; Holger Barth
    Keywords Toxikologie
    Subject Giftkunde ; Klinische Toxikologie
    Language German
    Size XLVIII, 1483 S. : Ill., graph. Darst.
    Edition 3., vollst. überarb. und erw. Aufl.
    Publisher Wiss. Verl.-Ges
    Publishing place Stuttgart
    Publishing country Germany
    Document type Book
    Old title Bis 2.Aufl. u.d.T. Marquardt, Hans: Lehrbuch der Toxikologie
    HBZ-ID HT017585917
    ISBN 978-3-8047-2876-9 ; 9783804731684 ; 3-8047-2876-6 ; 3804731686
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2009 A 10972 not available for loan Magazin
    2013 A 1064 available for loan (reading room) Lesesaal EG

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  9. Article: An Updated View on the Cellular Uptake and Mode-of-Action of Clostridioides difficile Toxins.

    Papatheodorou, Panagiotis / Minton, Nigel P / Aktories, Klaus / Barth, Holger

    Advances in experimental medicine and biology

    2024  Volume 1435, Page(s) 219–247

    Abstract: Research on the human gut pathogen Clostridioides (C.) difficile and its toxins continues to attract much attention as a consequence of the threat to human health posed by hypervirulent strains. Toxin A (TcdA) and Toxin B (TcdB) are the two major ... ...

    Abstract Research on the human gut pathogen Clostridioides (C.) difficile and its toxins continues to attract much attention as a consequence of the threat to human health posed by hypervirulent strains. Toxin A (TcdA) and Toxin B (TcdB) are the two major virulence determinants of C. difficile. Both are single-chain proteins with a similar multidomain architecture. Certain hypervirulent C. difficile strains also produce a third toxin, namely binary toxin CDT (C. difficile transferase). C. difficile toxins are the causative agents of C. difficile-associated diseases (CDADs), such as antibiotics-associated diarrhea and pseudomembranous colitis. For that reason, considerable efforts have been expended to unravel their molecular mode-of-action and the cellular mechanisms responsible for their uptake. Many of these studies have been conducted in European laboratories. Here, we provide an update on our previous review (Papatheodorou et al. Adv Exp Med Biol, 2018) on important advances in C. difficile toxins research.
    MeSH term(s) Humans ; Bacterial Toxins/toxicity ; Clostridioides difficile ; Biological Transport ; Antibodies, Bacterial ; Enterocolitis, Pseudomembranous
    Chemical Substances Bacterial Toxins ; Antibodies, Bacterial
    Language English
    Publishing date 2024-01-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 410187-X
    ISSN 0065-2598
    ISSN 0065-2598
    DOI 10.1007/978-3-031-42108-2_11
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3192: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Einzelsignatur: Show issues

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  10. Article ; Online: The Chaperonin TRiC/CCT Inhibitor HSF1A Protects Cells from Intoxication with Pertussis Toxin.

    Jia, Jinfang / Zoeschg, Manuel / Barth, Holger / Pulliainen, Arto T / Ernst, Katharina

    Toxins

    2024  Volume 16, Issue 1

    Abstract: Pertussis toxin (PT) is a bacterial ... ...

    Abstract Pertussis toxin (PT) is a bacterial AB
    MeSH term(s) Pertussis Toxin ; Bacterial Toxins/toxicity ; Clostridioides difficile ; Cytosol ; Antibodies, Bacterial ; Chaperonin Containing TCP-1
    Chemical Substances Pertussis Toxin (EC 2.4.2.31) ; Bacterial Toxins ; Antibodies, Bacterial ; Chaperonin Containing TCP-1 (EC 3.6.1.-)
    Language English
    Publishing date 2024-01-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2518395-3
    ISSN 2072-6651 ; 2072-6651
    ISSN (online) 2072-6651
    ISSN 2072-6651
    DOI 10.3390/toxins16010036
    Database MEDical Literature Analysis and Retrieval System OnLINE

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