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Article ; Online: Retraction: He-Wei granules (HWKL) combat cisplatin-induced nephrotoxicity and myelosuppression in rats by inhibiting oxidative stress, inflammatory cytokines and apoptosis.

Song, Zehai / Chang, Hang / Han, Na / Liu, Zhihui / Liu, Ye / Wang, Hui / Shao, Jingxuan / Wang, Zhonglin / Gao, Hao / Yin, Jun

RSC advances

2023 Volume 13, Issue 18, Page(s) 12276

Abstract: This retracts the article DOI: 10.1039/C7RA02830J.]. ...

Abstract	[This retracts the article DOI: 10.1039/C7RA02830J.].
Language	English
Publishing date	2023-04-19
Publishing country	England
Document type	Retraction of Publication
ISSN	2046-2069
ISSN (online)	2046-2069
DOI	10.1039/d3ra90036c
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Response of aerosol composition to the clean air actions in Baoji city of Fen-Wei River Basin.

Wang, Yichen / Li, Xia / Wang, Qiyuan / Zhou, Bianhong / Liu, Suixin / Tian, Jie / Hao, Qiang / Li, Guohui / Han, Yongming / Hang Ho, Steven Sai / Cao, Junji

Environmental research

2022 Volume 210, Page(s) 112936

Abstract: ... control measures and provide more scientific basis for the formulation of new measures. The Fen-Wei River Basin is ... Baoji was selected as a representative city in the Fen-Wei River Basin. The compositions of submicron ...

Abstract	The implementation of air pollution control measures could alter the compositions of submicron aerosols. Identifying the changes can evaluate the atmospheric responses of the implemented control measures and provide more scientific basis for the formulation of new measures. The Fen-Wei River Basin is the most air polluted region in China, and thereby is a key area for the reduction of emissions. Only limited studies determine the changes in the chemical compositions of submicron aerosols. In this study, Baoji was selected as a representative city in the Fen-Wei River Basin. The compositions of submicron aerosols were determined between 2014 and 2019. Organic fractions were determined through an online instrument (Quadrupole Aerosol Chemical Speciation Monitor, Q-ACSM) and source recognition was performed by the Multilinear Engine (ME-2). The Weather Research and Forecasting model coupled with Chemistry (WRF-Chem) was also employed to evaluate the contributions of emissions reduction and meteorological conditions to the changes of submicron aerosol compositions. The results indicate that the mass concentrations of submicron aerosols have been substantially decreased after implementation of air pollution control measures. This was mainly attributed to the emission reductions of sulfur dioxide (SO
MeSH term(s)	Aerosols/analysis ; Air Pollutants/analysis ; Air Pollution/analysis ; Air Pollution/prevention & control ; China ; Environmental Monitoring/methods ; Nitrates ; Nitrogen Oxides/analysis ; Particulate Matter/analysis ; Rivers
Chemical Substances	Aerosols ; Air Pollutants ; Nitrates ; Nitrogen Oxides ; Particulate Matter
Language	English
Publishing date	2022-02-16
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	205699-9
ISSN	1096-0953 ; 0013-9351
ISSN (online)	1096-0953
ISSN	0013-9351
DOI	10.1016/j.envres.2022.112936
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Article ; Online: A new non-stationary standardised streamflow index using the climate indices and the optimal anthropogenic indices as covariates in the Wei River Basin, China

Mingming Ren / Shanhu Jiang / Liliang Ren / Baisha Weng / Menghao Wang / Hao Cui / Chong-Yu Xu

Journal of Hydrology: Regional Studies, Vol 51, Iss , Pp 101649- (2024)

2024

Abstract: Study region: Catchment area above the Huaxian station along the Wei River Basin, China. Study ... applicable to the variable streamflow sequence of the Wei River Basin based on the climate index and ... model is more suitable for quantifying anthropogenic factors in the Wei River Basin. The NSSI performs ...

Abstract	Study region: Catchment area above the Huaxian station along the Wei River Basin, China. Study focus: This study attempts to construct a new Non-stationary Standardized Streamflow Index (NSSI) applicable to the variable streamflow sequence of the Wei River Basin based on the climate index and the optimal anthropogenic index, and analyse the drought characteristics of the basin. The climate index is used to quantify climate change factors and three anthropogenic indices are used to quantify the factor of human activities, including the reservoir index, the human-induced index calculated based on the Variable Infiltration Capacity (VIC) hydrological model and the Long Short-Term Memory (LSTM) model machine learning approach, respectively. New hydrological insights for the region: The human-induced index based on the LSTM model is more suitable for quantifying anthropogenic factors in the Wei River Basin. The NSSI performs better than the SSI in drought identification. The NSSI based on the LSTM model can capture more frequent severe drought and extreme drought events. The frequency of severe drought and extreme drought is higher in summer and autumn than in the others. The NSSI can better characterize the hydrological drought processes under a non-stationary condition, thus it can provide a more effective reference for regional drought assessment and related policy-making from the perspective of a changing environment.
Keywords	Non-stationary standardized streamflow index ; Hydrological drought ; Climate index ; Anthropogenic index ; Physical geography ; GB3-5030 ; Geology ; QE1-996.5
Subject code	550
Language	English
Publishing date	2024-02-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
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Article ; Online: Efficacy and safety of Jiu-Wei-Xi-Feng granules for treating tic disorders in children: study protocol for a randomized controlled equivalence trial.

Guo, Sheng-Xuan / Li, Rui-Ben / Hu, Si-Yuan / Cai, Qiu-Han / Zhong, Cheng-Liang / Hao, Rui-Min

Trials

2022 Volume 23, Issue 1, Page(s) 898

Abstract: ... in childhood. Jiu-Wei-Xi-Feng granules has been marketed in China for treating children with TD. As Long Gu (Os ... between Jiu-Wei-Xi-Feng granules (Os Draconis replaced by Concha Ostreae) (JWXFD) and Jiu-Wei-Xi-Feng ...

Abstract	Background: Tic disorders (TD) is a neuropsychiatric disease with twitch as the main manifestation in childhood. Jiu-Wei-Xi-Feng granules has been marketed in China for treating children with TD. As Long Gu (Os Draconis) in the composition of this Chinese patent medicine is a rare and expensive medicinal material protected by the Chinese government, therefore, we consider replacing it with Mu Li (Concha Ostreae) that has the same effect and is cheaper. This study is designed to evaluate the clinical equivalence between Jiu-Wei-Xi-Feng granules (Os Draconis replaced by Concha Ostreae) (JWXFD) and Jiu-Wei-Xi-Feng granules (original formula) (JWXFO) in children with TD (consumption of renal yin and liver wind stirring up internally syndrome). Methods/design: This is a multicenter, randomized, double-blind, equivalence trial comparing the efficacy and safety of JWXFD and JWXFO in treating Children with tic disorders (consumption of renal yin and liver wind stirring up internally syndrome). A total of 288 patients will be recruited and randomly assigned to two groups in a 1:1 ratio. The treatment course is 6 weeks, with a 2 weeks follow-up. The primary outcome is the mean change value from baseline to 6th week by the Yale Global Tic Severity Scale total tic score (YGTSS-TTS). Secondary outcomes include total effective rate of tic, Yale Global Tic Severity Scale (YGTSS) scores and its factor scores (the degree of motor tics, phonic tics and social function damage), Clinical Global Impression-Severity scale, and TCM syndrome efficacy. Discussion: The design of this study refers to a large number of similar research design points, and asked for opinions of peer experts, and finally reached a consensus. This trial will provide high-quality evidence on the clinical equivalence between JWXFD and JWXFO and provide a basis for the marketing of JWXFD. Trial registration: ChiCTR2000032312 Registered on 25 April 2020, http://www.chictr.org.cn/showproj.aspx?proj=52630.
MeSH term(s)	Child ; Humans ; Tics/therapy ; Treatment Outcome ; Tic Disorders/diagnosis ; Tic Disorders/drug therapy ; Double-Blind Method ; Syndrome ; Nonprescription Drugs ; Randomized Controlled Trials as Topic ; Multicenter Studies as Topic
Chemical Substances	Nonprescription Drugs
Language	English
Publishing date	2022-10-22
Publishing country	England
Document type	Clinical Trial Protocol ; Journal Article
ZDB-ID	2040523-6
ISSN	1745-6215 ; 1468-6694 ; 1745-6215
ISSN (online)	1745-6215
ISSN	1468-6694 ; 1745-6215
DOI	10.1186/s13063-022-06802-y
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Article: Identifying drought propagation by simultaneously considering linear and nonlinear dependence in the Wei River basin of the Loess Plateau, China

Fang, Wei / Huang, Shengzhi / Huang, Qiang / Huang, Guohe / Wang, Hao / Leng, Guoyong / Wang, Lu

Journal of hydrology. 2020 Dec., v. 591

2020

Abstract: ... precipitation deficits. A case study is conducted for the Wei River basin of the Loess Plateau, China ...

Abstract	Meteorological drought propagating to hydrological drought usually occurs with a noticeable time delay due to the catchment buffering effect. Knowledge gain in the delayed hydrological response is indispensable for developing timely drought monitoring systems. In this study, a two-stage statistical framework is proposed for identifying the response time of hydrological droughts to meteorological droughts at a weekly resolution. Candidate response time is initially selected by exclusively evaluating linear or nonlinear correlations between precipitation and streamflow anomalies. In the second stage, the optimal response time is determined, at which the greatest number of streamflow deficits can be monitored by concurrent precipitation deficits. A case study is conducted for the Wei River basin of the Loess Plateau, China to investigate the spatio-temporal variability in drought response time under a changing environment. Results indicate that hydrological droughts respond to meteorological droughts with time lags of 25–39 weeks, exhibiting noticeable spatial variability. The long-time hydrological response is expected where there are sufficient vegetation and loess deposits. Drought response time identification for each calendar month reveals the long-term and short-term hydrological response in winter and summer, respectively. A time-varying baseflow index is found to be positively related to the drought response time, therefore having control on its marked seasonality. In a changing environment, summer hydrological droughts tend to respond to precipitation variability at longer time scales, while decreasing response time is noticed in winter. A preliminary attribution analysis highlights that changes in meteorological drought severity and catchment water storage in combination exert control on the temporal variability in drought response time over the past half-century. Findings of the study may favor hydrological drought monitoring dependent on precipitation deficit information available at large spatial extent.
Keywords	base flow ; case studies ; drought ; loess ; summer ; temporal variation ; vegetation ; water storage ; watersheds ; winter ; China
Language	English
Dates of publication	2020-12
Publishing place	Elsevier B.V.
Document type	Article
Note	NAL-AP-2-clean
ZDB-ID	1473173-3
ISSN	1879-2707 ; 0022-1694
ISSN (online)	1879-2707
ISSN	0022-1694
DOI	10.1016/j.jhydrol.2020.125287
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Article ; Online: Ba-Wei-Die-Huang-Wan (Hachimi-jio-gan) can ameliorate ketamine-induced cystitis by modulating neuroreceptors, inflammatory mediators, and fibrogenesis in a rat model.

Lee, Wei-Chia / Tain, You-Lin / Chuang, Yao-Chi / Tsai, Cheng-Nan / Yu, Chun-Chieh / Su, Chia-Hao

Neurourology and urodynamics

2019 Volume 38, Issue 8, Page(s) 2159–2169

Abstract: Aim: We investigated the effects of Ba-Wei-Die-Huang-Wan (BWDHW) on ketamine-induced cystitis (KIC ...

Abstract	Aim: We investigated the effects of Ba-Wei-Die-Huang-Wan (BWDHW) on ketamine-induced cystitis (KIC) in a rat model. Methods: Female Sprague-Dawley rats were distributed into three groups: control (saline), ketamine (25 mg/kg/day for 28 days), or ketamine (25 mg/kg/day for 28 days) plus BWDHW (90 mg/kg/day, started from day 14). Functional magnetic resonance imaging (fMRI), metabolic cage study, and cystometry were evaluated. Bladder histology was evaluated. Western blots of the bladder proteins were carried out. Results: Compared with controls, ketamine-treated rats showed stronger fMRI intensity in the periaqueductal gray area and bladder overactivity in the bladder functional study, but the ketamine/BWDHW-treated rats did not. Furthermore, ketamine breached the uroplakin III membrane at the apical surface of the urothelium, enhanced substance P spread over the urothelium, induced suburothelial hemorrhage and monocyte/macrophage infiltration, and caused interstitial fibrosis deposition. By contrast, the BWDHW-treated rats exhibited less substance P spread, lower suburothelial monocyte/macrophage infiltration, and lower interstitial fibrosis deposition. The ketamine group showed significant overexpression of neuroreceptors in the bladder mucosa (the transient receptor potential vanilloid 1 and M Conclusion: BWDHW could exert therapeutic effects by inhibiting the upregulation of neuroreceptors, modulating inflammatory mediators, suppressing fibrogenesis, and ameliorating bladder overactivity in rats with KIC.
MeSH term(s)	Animals ; Collagen/drug effects ; Collagen/metabolism ; Cyclooxygenase 2/drug effects ; Cyclooxygenase 2/metabolism ; Cystitis/chemically induced ; Cystitis/metabolism ; Cystitis/pathology ; Cystitis/physiopathology ; Drugs, Chinese Herbal/pharmacology ; Female ; Fibronectins/drug effects ; Fibronectins/metabolism ; Functional Neuroimaging ; Intercellular Adhesion Molecule-1/drug effects ; Intercellular Adhesion Molecule-1/metabolism ; Interleukin-1beta/drug effects ; Interleukin-1beta/metabolism ; Interleukin-6/metabolism ; Ketamine/adverse effects ; Magnetic Resonance Imaging ; NF-kappa B/drug effects ; NF-kappa B/metabolism ; Periaqueductal Gray/diagnostic imaging ; Rats ; Rats, Sprague-Dawley ; Receptors, Muscarinic/drug effects ; Receptors, Muscarinic/metabolism ; Sensory Receptor Cells ; Substance P/drug effects ; Substance P/metabolism ; TRPV Cation Channels/drug effects ; TRPV Cation Channels/metabolism ; Transforming Growth Factor beta1/drug effects ; Transforming Growth Factor beta1/metabolism ; Tumor Necrosis Factor-alpha/drug effects ; Tumor Necrosis Factor-alpha/metabolism ; Urinary Bladder/drug effects ; Urinary Bladder/metabolism ; Urinary Bladder/pathology ; Urinary Bladder/physiopathology ; Urinary Bladder, Overactive/chemically induced ; Urinary Bladder, Overactive/metabolism ; Urinary Bladder, Overactive/pathology ; Urinary Bladder, Overactive/physiopathology ; Urothelium/drug effects ; Urothelium/metabolism
Chemical Substances	Drugs, Chinese Herbal ; Fibronectins ; IL1B protein, rat ; Il6 protein, rat ; Interleukin-1beta ; Interleukin-6 ; NF-kappa B ; Receptors, Muscarinic ; TRPV Cation Channels ; TRPV1 receptor ; Tgfb1 protein, rat ; Transforming Growth Factor beta1 ; Tumor Necrosis Factor-alpha ; hachimijiogan ; Intercellular Adhesion Molecule-1 (126547-89-5) ; Substance P (33507-63-0) ; Ketamine (690G0D6V8H) ; Collagen (9007-34-5) ; Cyclooxygenase 2 (EC 1.14.99.1) ; Ptgs2 protein, rat (EC 1.14.99.1)
Language	English
Publishing date	2019-09-20
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	604904-7
ISSN	1520-6777 ; 0733-2467
ISSN (online)	1520-6777
ISSN	0733-2467
DOI	10.1002/nau.24165
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Article: Response of aerosol composition to the clean air actions in Baoji city of Fen-Wei River Basin

Wang, Yichen / Li, Xia / Wang, Qiyuan / Zhou, Bianhong / Liu, Suixin / Tian, Jie / Hao, Qiang / Li, Guohui / Han, Yongming / Hang Ho, Steven Sai / Cao, Junji

Environmental research. 2022 July, v. 210

2022

Abstract	The implementation of air pollution control measures could alter the compositions of submicron aerosols. Identifying the changes can evaluate the atmospheric responses of the implemented control measures and provide more scientific basis for the formulation of new measures. The Fen-Wei River Basin is the most air polluted region in China, and thereby is a key area for the reduction of emissions. Only limited studies determine the changes in the chemical compositions of submicron aerosols. In this study, Baoji was selected as a representative city in the Fen-Wei River Basin. The compositions of submicron aerosols were determined between 2014 and 2019. Organic fractions were determined through an online instrument (Quadrupole Aerosol Chemical Speciation Monitor, Q-ACSM) and source recognition was performed by the Multilinear Engine (ME-2). The Weather Research and Forecasting model coupled with Chemistry (WRF-Chem) was also employed to evaluate the contributions of emissions reduction and meteorological conditions to the changes of submicron aerosol compositions. The results indicate that the mass concentrations of submicron aerosols have been substantially decreased after implementation of air pollution control measures. This was mainly attributed to the emission reductions of sulfur dioxide (SO₂) and primary organic aerosol (POA). In addition, the main components that drove the pollution episodes swapped from POA, sulfate, nitrate and less-oxidized organic (LO-OOA) in 2014 to nitrate and more-oxidized OOA (MO-OOA) in 2019. Due to the changes of chemical compositions of both precursors and secondary pollutants, the pollution control measures should be modernized to focus on the emissions of ammonia (NH₃), nitrogen oxides (NOₓ) and volatile organic compounds (VOCₛ) in this region.
Keywords	aerosols ; air ; air pollution control ; ammonia ; chemical speciation ; nitrates ; nitrogen ; pollution ; research ; sulfates ; sulfur dioxide ; volatile organic compounds ; watersheds
Language	English
Dates of publication	2022-07
Publishing place	Elsevier Inc.
Document type	Article
ZDB-ID	205699-9
ISSN	1096-0953 ; 0013-9351
ISSN (online)	1096-0953
ISSN	0013-9351
DOI	10.1016/j.envres.2022.112936
Database	NAL-Catalogue (AGRICOLA)

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Article: Erratum: Bao, L.; Cai, W.; Zhang, X.; Liu, J.; Chen, H.; Wei, Y.; Jia, X.; Bai, Z. Distinct Microbial Community of Phyllosphere Associated with Five Tropical Plants on Yongxing Island, South China Sea.

Bao, Lijun / Cai, Wenyang / Zhang, Xiaofen / Liu, Jinhong / Chen, Hao / Wei, Yuansong / Jia, Xiuxiu / Bai, Zhihui

Microorganisms

2020 Volume 8, Issue 4

Abstract: The authors wish to make the following erratum in this paper [ ... ]. ...

Abstract	The authors wish to make the following erratum in this paper [...].
Language	English
Publishing date	2020-04-15
Publishing country	Switzerland
Document type	Published Erratum
ZDB-ID	2720891-6
ISSN	2076-2607
ISSN	2076-2607
DOI	10.3390/microorganisms8040570
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Article ; Online: Proteomic analysis of functional dyspepsia in stressed rats treated with traditional Chinese medicine "Wei Kangning".

Wei, Wei / Li, Xia / Hao, Jianjun / Zhang, Rong / Guo, Jianli / Zong, Yiqiang / Lu, Yanjun / Qu, Shen / Tian, Jun

Journal of gastroenterology and hepatology

2011 Volume 26, Issue 9, Page(s) 1425–1433

Abstract: ... mechanisms of Chinese traditional medicine, such as typical traditional Chinese medicine, Wei Kangning, there ... rats via tail damping and the rats were treated with traditional Chinese medicine, Wei Kangning ... corresponding with traditional Chinese medicine, Wei Kangning, administration. Twenty-eight of these proteins ...

Abstract	Background and aim: Chinese traditional medical science is generally used as a therapeutic method against functional dyspepsia (FD) in China. Although great effort is made to understand the pharmaceutical mechanisms of Chinese traditional medicine, such as typical traditional Chinese medicine, Wei Kangning, there are still many mysteries to be uncovered. Methods: The model of FD was established by stimulating rats via tail damping and the rats were treated with traditional Chinese medicine, Wei Kangning. The proteins of the rat gastrointestinal tissues were extracted and run by 2-DE, then the differential proteins were identified using matrix-assisted laser desorption ionisation time-of-flight mass spectrometry and validated with Western blotting or fluorescent quantitation polymerase chain reaction. Results: A total of 228 unique proteins in FD model rats were detected with significant changes in their expression levels corresponding with traditional Chinese medicine, Wei Kangning, administration. Twenty-eight of these proteins were identified, which are involved in many biological functions, such as organism antioxidant enzymes, energy metabolism, glutathione S-transferase, pi2, superoxide dismutase 2 and alpha-enolase and so on. Conclusions: These proteomic results presented therefore provide additional support to the hypothesis that glutathione S-transferase, pi2, superoxide dismutase 2, α-enolase and voltage-dependent anion channel are the targets of FD treated with traditional Chinese medicine, Wei Kangning.
MeSH term(s)	Animals ; Blotting, Western ; Disease Models, Animal ; Drugs, Chinese Herbal/pharmacology ; Dyspepsia/drug therapy ; Dyspepsia/etiology ; Dyspepsia/metabolism ; Dyspepsia/physiopathology ; Electrophoresis, Gel, Two-Dimensional ; Gastrointestinal Motility/drug effects ; Glutathione S-Transferase pi/metabolism ; Intestines/drug effects ; Intestines/metabolism ; Intestines/physiopathology ; Phosphopyruvate Hydratase/metabolism ; Proteomics/methods ; Rats ; Rats, Wistar ; Real-Time Polymerase Chain Reaction ; Reproducibility of Results ; Reverse Transcriptase Polymerase Chain Reaction ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization ; Stomach/drug effects ; Stomach/metabolism ; Stomach/physiopathology ; Stress, Psychological/complications ; Superoxide Dismutase/metabolism ; Voltage-Dependent Anion Channels/drug effects ; Voltage-Dependent Anion Channels/metabolism
Chemical Substances	Drugs, Chinese Herbal ; Voltage-Dependent Anion Channels ; weikangning ; Superoxide Dismutase (EC 1.15.1.1) ; superoxide dismutase 2 (EC 1.15.1.1) ; Glutathione S-Transferase pi (EC 2.5.1.18) ; Phosphopyruvate Hydratase (EC 4.2.1.11)
Language	English
Publishing date	2011-09
Publishing country	Australia
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	632882-9
ISSN	1440-1746 ; 0815-9319
ISSN (online)	1440-1746
ISSN	0815-9319
DOI	10.1111/j.1440-1746.2010.06566.x
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Article: Qu wei jiu wen

Hong, Hao

Qu wei jiu wen, Zhu, Bian, Di 1 ban. - Zheng zhou : Da xiang chu ban she

2008

Document type	Article
Database	Former special subject collection: coastal and deep sea fishing

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