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  1. Book ; Online: Female Genital Mutilation/Cutting

    Nakamura, Kyoko / Miyachi, Kaori / Miyawaki, Yukio / Toda, Makiko / Miyawaki, Yukio

    Global Zero Tolerance Policy and Diverse Responses from African and Asian Local Communities

    2023  

    Keywords Human rights ; Political science & theory ; Development studies ; Gender studies, gender groups ; Central government policies ; Politics & government ; Female Genital Cutting (FGC) ; Female Genital Mutilation (FGM) ; Female Circumcision ; Zero Tolerance ; African Women ; Male Circumcision
    Language English
    Size 1 electronic resource (193 pages)
    Publisher Springer Nature
    Publishing place Singapore
    Document type Book ; Online
    Note English
    HBZ-ID HT030376471
    ISBN 9789811967238 ; 9811967237
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Female Genital Mutilation/Cutting

    Nakamura, Kyoko / Miyachi, Kaori / Miyawaki, Yukio / Toda, Makiko

    Global Zero Tolerance Policy and Diverse Responses from African and Asian Local Communities

    2023  

    Author's details edited by Kyoko Nakamura, Kaori Miyachi, Yukio Miyawaki, Makiko Toda
    Keywords Human rights ; Economic development ; Sex ; Family policy ; Social justice
    Subject code 341.48
    Language English
    Size 1 Online-Ressource (XVII, 193 p. 7 illus., 2 illus. in color)
    Edition 1st ed. 2023
    Publisher Springer Nature Singapore ; Imprint: Springer
    Publishing place Singapore
    Document type Book ; Online
    HBZ-ID HT021736439
    ISBN 978-981-19-6723-8 ; 9789811967221 ; 9789811967245 ; 9789811967252 ; 981-19-6723-7 ; 9811967229 ; 9811967245 ; 9811967253
    DOI 10.1007/978-981-19-6723-8
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online ; E-Book: Medical applications of iPS cells

    Inoue, Haruhisa / Nakamura, Yukio

    innovation in medical sciences

    (Current human cell research and applications)

    2019  

    Author's details Haruhisa Inoue, Yukio Nakamu editors
    Series title Current human cell research and applications
    Keywords Stem cells/Technological innovations ; Cell culture
    Subject code 616.02774
    Language English
    Size 1 Online-Ressource (x, 190 Seiten), Illustrationen
    Publisher Springer
    Publishing place Singapore
    Publishing country Singapore
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020036313
    ISBN 978-981-13-3672-0 ; 9789811336713 ; 981-13-3672-5 ; 9811336717
    DOI 10.1007/978-981-13-3672-0
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article ; Online: A Short-Term Zinc-Deficient Diet Maintains Serum Calcium Concentrations through Ca Absorption-Related Gene Expression in Rats.

    Suzuki, Takako / Suzuki, Kazuharu / Takahashi, Jun / Nakamura, Yukio

    Journal of nutritional science and vitaminology

    2024  Volume 70, Issue 1, Page(s) 82–87

    Abstract: We investigated the effects of short-term dietary zinc deficiency on zinc and calcium metabolism. Four-week-old male Wistar rats were divided into two pair-fed groups for a 1-wk treatment: zinc-deficient group (ZD, 1 ppm); control group (PF, 30 ppm). The ...

    Abstract We investigated the effects of short-term dietary zinc deficiency on zinc and calcium metabolism. Four-week-old male Wistar rats were divided into two pair-fed groups for a 1-wk treatment: zinc-deficient group (ZD, 1 ppm); control group (PF, 30 ppm). The mRNA expression of zinc transporters, such as Slc39a (Zip) 4, Zip5, Zip10, and Slc30a (ZnT) 1, in various tissues (liver, kidney, and duodenum) quickly responded to dietary zinc deficiency. Although there was no significant difference in serum calcium concentrations between the PF and ZD groups, serum 1,25-dihydroxycholecalciferol (1,25(OH)
    MeSH term(s) Rats ; Male ; Animals ; Calcium/metabolism ; Vitamin D3 24-Hydroxylase/genetics ; Rats, Wistar ; Zinc ; Diet ; Gene Expression ; RNA, Messenger/metabolism
    Chemical Substances Calcium (SY7Q814VUP) ; Vitamin D3 24-Hydroxylase (EC 1.14.15.16) ; Zinc (J41CSQ7QDS) ; RNA, Messenger
    Language English
    Publishing date 2024-02-28
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 191366-9
    ISSN 1881-7742 ; 0301-4800
    ISSN (online) 1881-7742
    ISSN 0301-4800
    DOI 10.3177/jnsv.70.82
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Incidence and preventive treatment for deep vein thrombosis with our own preventive protocol in total hip and knee arthroplasty

    Takashige Momose / Masaki Nakano / Yukio Nakamura / Takashi Maeda / Masashi Nawata

    PLoS ONE, Vol 19, Iss

    2024  Volume 1

    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Safety of antiplatelet therapy during the perioperative period of revascularization surgery for moyamoya disease patients with ischemic onset.

    Nakamura, Akihiro / Takasu, Syuntaro / Seki, Yukio / Saito, Ryuta

    Nagoya journal of medical science

    2024  Volume 86, Issue 1, Page(s) 82–90

    Abstract: For patients with moyamoya disease, antiplatelet agents are often used during the perioperative periods of revascularization surgeries to prevent ischemic events. However, antiplatelet therapy is associated with the risk of hemorrhagic complications. ... ...

    Abstract For patients with moyamoya disease, antiplatelet agents are often used during the perioperative periods of revascularization surgeries to prevent ischemic events. However, antiplatelet therapy is associated with the risk of hemorrhagic complications. Further, the influence of antiplatelet therapy on perioperative ischemic or hemorrhagic complications has not been investigated. This study aimed to determine the impact of antiplatelet agents on adult moyamoya disease patients with ischemic onset during the perioperative period. From January 2016 to December 2020, 183 consecutive combined (direct and indirect) revascularization surgeries for moyamoya disease patients were performed. Among these surgeries, 96 consecutive combined revascularization surgeries for adult moyamoya disease patients with ischemic onset were analyzed and perioperative ischemic and hemorrhagic complications were reviewed. Antiplatelet agents were continued during the perioperative period including on the day of surgery and the day after the surgery. Among 96 surgeries, no hemorrhagic complications occurred postoperatively. Infarction occurred in five cases (5.2%). Among the five cases, neurological deficits persisted in two cases and improved in three. The median value of bleeding volume was 112.5 mL (interquartile range, 80.0 - 200.0). Twenty-five cases (26.0%) needed blood transfusion. The modified Rankin Scale score deteriorated in two cases due to cerebral infarction. The incidence of hemorrhagic and ischemic complications after combined revascularization surgery in patients with ischemic moyamoya disease under antiplatelet therapy was low, indicating the safety of continued antiplatelet therapy.
    MeSH term(s) Adult ; Humans ; Platelet Aggregation Inhibitors/adverse effects ; Treatment Outcome ; Moyamoya Disease/surgery ; Perioperative Period/adverse effects ; Postoperative Complications/prevention & control ; Postoperative Complications/etiology ; Retrospective Studies ; Cerebral Revascularization/adverse effects
    Chemical Substances Platelet Aggregation Inhibitors
    Language English
    Publishing date 2024-03-04
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 193148-9
    ISSN 2186-3326 ; 0027-7622
    ISSN (online) 2186-3326
    ISSN 0027-7622
    DOI 10.18999/nagjms.86.1.82
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Genetic diversity among the present Japanese population: evidence from genotyping of human cell lines established in Japan.

    Kasai, Fumio / Fukushima, Makoto / Miyagi, Yohei / Nakamura, Yukio

    Human cell

    2024  

    Abstract: Japan is often assumed to have a highly homogeneous ethnic population, because it is an island country. This is evident in human cell lines collected from cell banks; however, these genotypes have not been thoroughly characterized. To examine the ... ...

    Abstract Japan is often assumed to have a highly homogeneous ethnic population, because it is an island country. This is evident in human cell lines collected from cell banks; however, these genotypes have not been thoroughly characterized. To examine the population genotypes of human cell lines established in Japan, we conducted SNP genotyping on 57 noncancerous cell lines and 43 lung cancer cell lines. Analysis of biogeographic ancestry revealed that 58 cell lines had non-admixed Japanese genotypes, 21 cell lines had an admixture of Japanese and East Asian genotypes, and the remaining 21 cell lines had East Asian genotypes. The proportion of non-admixed Japanese genotypes was similar between lung cancer and noncancerous cell lines, suggesting that patients in Japan may not exclusively have Japanese genotypes. This could influence the incidence of inherited diseases and should be taken into account in personalized medicine tailored to genetic background. The genetic makeup of the present-day Japanese population cannot be fully explained by the ancestral Jomon and Yayoi lineages. Instead, it is necessary to consider a certain level of genetic admixture between Japanese and neighboring Asian populations. Our study revealed genetic variation among human cell lines derived from Japanese individuals, reflecting the diversity present within the Japanese population.
    Language English
    Publishing date 2024-04-19
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 1149134-6
    ISSN 1749-0774 ; 0914-7470
    ISSN (online) 1749-0774
    ISSN 0914-7470
    DOI 10.1007/s13577-024-01055-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Ascorbic acid predominantly kills cancer stem cell-like cells in the hepatocellular carcinoma cell line Li-7 and is more effective at low cell density and in small spheroids.

    Seyama, Yusuke / Sudo, Kazuhiro / Yamada, Takeshi / Tsuchiya, Kiichiro / Nakamura, Yukio

    Biochemical and biophysical research communications

    2024  Volume 709, Page(s) 149816

    Abstract: The development of therapies that target cancer stem cells (CSCs) is an important challenge in cancer research. The antioxidant system is enhanced in CSCs, which may lead to resistance to existing therapies. Ascorbic acid (AA) has the potential to act as ...

    Abstract The development of therapies that target cancer stem cells (CSCs) is an important challenge in cancer research. The antioxidant system is enhanced in CSCs, which may lead to resistance to existing therapies. Ascorbic acid (AA) has the potential to act as both an antioxidant and a pro-oxidant agent, but its effects on CSCs are a subject of current research. Here, we investigated the effect of AA focusing specifically on CSCs with the hepatocellular carcinoma cell line Li-7. The Li-7 cell line is heterogenous consisting of CD166
    MeSH term(s) Animals ; Mice ; Carcinoma, Hepatocellular/pathology ; Liver Neoplasms/pathology ; Cell Line, Tumor ; Ascorbic Acid/pharmacology ; Ascorbic Acid/metabolism ; Antioxidants/pharmacology ; Antioxidants/metabolism ; Neoplastic Stem Cells/pathology
    Chemical Substances Ascorbic Acid (PQ6CK8PD0R) ; Antioxidants
    Language English
    Publishing date 2024-03-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 205723-2
    ISSN 1090-2104 ; 0006-291X ; 0006-291X
    ISSN (online) 1090-2104 ; 0006-291X
    ISSN 0006-291X
    DOI 10.1016/j.bbrc.2024.149816
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Development of Augmented-Reality-Based Magnetic Field Visualization System as an Educational Tool.

    Nakamura, Hisahide / Mizuno, Yukio

    Sensors (Basel, Switzerland)

    2022  Volume 22, Issue 20

    Abstract: Electromagnetism is a difficult subject to learn because the phenomenon is not observed directly and does not have a perceivable, concrete image. The visualization of the phenomenon will greatly help beginners understand electromagnetics. This paper ... ...

    Abstract Electromagnetism is a difficult subject to learn because the phenomenon is not observed directly and does not have a perceivable, concrete image. The visualization of the phenomenon will greatly help beginners understand electromagnetics. This paper proposes an augmented-reality-based visualization system of the magnetic flux density around current-generating objects. The system can be realized with a portable magnetic field sensor and a familiar device-a smartphone. The effectiveness of the system is verified through experiments, and our findings suggest that the system can effectively help an operator gain an intuitive understanding of the magnetic flux density.
    Language English
    Publishing date 2022-10-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s22208026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Psychological origin of quantum logic: An orthomodular lattice derived from natural-born intelligence without Hilbert space.

    Gunji, Yukio Pegio / Nakamura, Kyoko

    Bio Systems

    2022  Volume 215-216, Page(s) 104649

    Abstract: While the role of quantum theory becomes increasingly important through molecular computing and quantum cognition, it is still unclear how quantum mechanics can be involved in macroscopic phenomena. We previously argued the origin of quantum logic in ... ...

    Abstract While the role of quantum theory becomes increasingly important through molecular computing and quantum cognition, it is still unclear how quantum mechanics can be involved in macroscopic phenomena. We previously argued the origin of quantum logic in terms of lattice theory; however, we do not refer to Hilbert space very much. Here, we show the psychological origin of quantum logic (i.e., orthomodular lattice) by not using Hilbert space. After showing how Hilbert space plays a role in constructing an orthomodular lattice, we show the idea of natural-born intelligence, in which a binary opposition pair can constitute not only positive but negative antinomy. In taking an object outside and an image inside a brain as that binary opposition pair, the structure entailing positive and negative antinomy is expressed as a specific binary relation consisting of multiple diagonal relations, which is called traumatic relation. Finally, we show that the traumatic relation leads to an orthomodular lattice without Hilbert space.
    MeSH term(s) Brain ; Cognition ; Intelligence ; Logic ; Quantum Theory
    Language English
    Publishing date 2022-02-25
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 186234-0
    ISSN 1872-8324 ; 0303-2647
    ISSN (online) 1872-8324
    ISSN 0303-2647
    DOI 10.1016/j.biosystems.2022.104649
    Database MEDical Literature Analysis and Retrieval System OnLINE

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