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  1. Book: Marine toxins as research tools

    Fusetani, Nobuhiro

    (Progress in molecular and subcellular biology ; 46 : Marine molecular biotechnology)

    2009  

    Author's details Nobuhiro Fusetani ... ed
    Series title Progress in molecular and subcellular biology ; 46 : Marine molecular biotechnology
    Collection
    Keywords Marine toxins ; Meer ; Toxin
    Subject Ozean ; See ; Weltmeer ; Seegebiet ; Meere ; Ozeane ; Weltmeere ; Biogenes Gift
    Subject code 615.94
    Language English
    Size XIV, 259 S. : Ill., graph. Darst.
    Publisher Springer
    Publishing place Berlin u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT015859751
    ISBN 978-3-540-87892-6 ; 3-540-87892-0 ; 9783540878957 ; 3540878955
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    098/835 available for loan (reading room) Freihandmagazin (U1)

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  2. Book: Antifouling compounds

    Fusetani, Nobuhiro

    with 15 tables

    (Progress in molecular and subcellular biology ; 42 : Marine molecular biotechnology)

    2006  

    Author's details Nobuhiro Fusetani ... (ed.)
    Series title Progress in molecular and subcellular biology ; 42 : Marine molecular biotechnology
    Collection
    Keywords Meer ; Organismus ; Antifouling-Wirkstoff ; Antifoulingfarbe
    Subject Lebewesen ; Organismen ; Ozean ; See ; Weltmeer ; Seegebiet ; Meere ; Ozeane ; Weltmeere
    Language English
    Size XIII, 225 S. : Ill., graph. Darst.
    Publisher Springer
    Publishing place Berlin u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT014736472
    ISBN 978354030014X ; 978-3-540-30014-4 ; 3-540-30014-7
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    068/592 available for loan (reading room) Freihandmagazin (U1)

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  3. Article ; Online: Two Onnamide Analogs from the Marine Sponge

    Nakamura, Fumiaki / Kimura, Hiroshi / Fusetani, Nobuhiro / Nakao, Yoichi

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 6

    Abstract: Two previously unreported onnamide analogs, ... ...

    Abstract Two previously unreported onnamide analogs, 2
    MeSH term(s) Animals ; Humans ; Theonella/chemistry ; Porifera/chemistry ; Pyrans ; HeLa Cells ; Polyenes/pharmacology ; Molecular Structure
    Chemical Substances onnamide (115204-07-4) ; Pyrans ; Polyenes
    Language English
    Publishing date 2023-03-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28062524
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.MO 81: Show issues

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  4. Article ; Online: Two Onnamide Analogs from the Marine Sponge Theonella conica

    Fumiaki Nakamura / Hiroshi Kimura / Nobuhiro Fusetani / Yoichi Nakao

    Molecules, Vol 28, Iss 2524, p

    Evaluation of Geometric Effects in the Polyene Systems on Biological Activity

    2023  Volume 2524

    Abstract: Two previously unreported onnamide analogs, 2 Z - and 6 Z -onnamides A ( 1 and 2 ), were isolated from the marine sponge Theonella conica collected at Amami-Oshima Is., Kagoshima Prefecture, Japan. Structures of compounds 1 and 2 were elucidated by ... ...

    Abstract Two previously unreported onnamide analogs, 2 Z - and 6 Z -onnamides A ( 1 and 2 ), were isolated from the marine sponge Theonella conica collected at Amami-Oshima Is., Kagoshima Prefecture, Japan. Structures of compounds 1 and 2 were elucidated by spectral analysis. Structure–activity relationships (SARs) for effects on histone modifications and cytotoxicity against HeLa and P388 cells were characterized. The geometry in the polyene systems of onnamides affected the histone modification levels and cytotoxicity.
    Keywords onnamides ; Theonella sp ; marine sponges ; histone modifications ; cytotoxicity ; marine natural products ; Organic chemistry ; QD241-441
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  5. Article ; Online: Aurantoside L, a New Tetramic Acid Glycoside with Anti-Leishmanial Activity Isolated from the Marine Sponge

    Oyadomari, Yasumoto / Goto, Yasuyuki / Suganuma, Keisuke / Kawazu, Shin-Ichiro / Becking, Leontine E / Fusetani, Nobuhiro / Nakao, Yoichi

    Marine drugs

    2024  Volume 22, Issue 4

    Abstract: A new tetramic acid glycoside, aurantoside L ( ...

    Abstract A new tetramic acid glycoside, aurantoside L (
    MeSH term(s) Porifera/chemistry ; Animals ; Glycosides/pharmacology ; Glycosides/chemistry ; Glycosides/isolation & purification ; Leishmania/drug effects ; Antiprotozoal Agents/pharmacology ; Antiprotozoal Agents/chemistry ; Antiprotozoal Agents/isolation & purification ; Pyrrolidinones/pharmacology ; Pyrrolidinones/chemistry ; Pyrrolidinones/isolation & purification ; Japan ; Inhibitory Concentration 50
    Chemical Substances Glycosides ; tetramic acid (503-83-3) ; Antiprotozoal Agents ; Pyrrolidinones
    Language English
    Publishing date 2024-04-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175190-0
    ISSN 1660-3397 ; 1660-3397
    ISSN (online) 1660-3397
    ISSN 1660-3397
    DOI 10.3390/md22040171
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Coronarin D, a Metabolite from the Wild Turmeric,

    Otsuka, Satoshi / Kawamura, Midori / Fujino, Shutaro / Nakamura, Fumiaki / Arai, Daisuke / Fusetani, Nobuhiro / Nakao, Yoichi

    Journal of agricultural and food chemistry

    2022  Volume 70, Issue 10, Page(s) 3300–3309

    Abstract: Plants in the ... ...

    Abstract Plants in the genus
    MeSH term(s) Astrocytes/metabolism ; Cell Differentiation ; Cells, Cultured ; Curcuma ; Diterpenes ; Neural Stem Cells/physiology
    Chemical Substances Diterpenes ; coronarin D
    Language English
    Publishing date 2022-03-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241619-0
    ISSN 1520-5118 ; 0021-8561
    ISSN (online) 1520-5118
    ISSN 0021-8561
    DOI 10.1021/acs.jafc.2c00020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1172: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Chemical cues for intraspecific chemical communication and interspecific interactions in aquatic environments: applications for fisheries and aquaculture

    Kamio, Michiya / Yambe, Hidenobu / Fusetani, Nobuhiro

    Fish Sci. 2022 Mar., v. 88, no. 2 p.203-239

    2022  

    Abstract: Aquatic organisms detect chemical cues to sense the local environment, for example, to find a mate, locate food, and identify danger. Knowledge of chemical cues can be used in aquaculture, in practical applications such as controlling mating behavior to ... ...

    Abstract Aquatic organisms detect chemical cues to sense the local environment, for example, to find a mate, locate food, and identify danger. Knowledge of chemical cues can be used in aquaculture, in practical applications such as controlling mating behavior to increase fertility, enhance feeding, and decrease stress; in fisheries, by catching selected species with low-cost artificial attractants; and to address maritime issues, by decreasing biofouling. Aquatic organisms also detect chemical cues related to global environmental changes, ocean acidification, and increases in ocean plastics, all of which can affect their chemosensory behaviors. Here we discuss the nature of chemical cues and chemosensory biology and ecology of aquatic organisms, and potential applications with an emphasis on sex pheromones in commercially important and well-studied animals, namely, decapod crustaceans and fish.
    Keywords Decapoda ; aquaculture ; attractants ; biofouling ; chemical communication ; fish ; ocean acidification
    Language English
    Dates of publication 2022-03
    Size p. 203-239.
    Publishing place Springer Japan
    Document type Article ; Online
    Note Review
    ZDB-ID 1192654-5
    ISSN 1444-2906 ; 0919-9268
    ISSN (online) 1444-2906
    ISSN 0919-9268
    DOI 10.1007/s12562-021-01563-0
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 5906: Show issues

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  8. Article ; Online: Antifouling marine natural products.

    Fusetani, Nobuhiro

    Natural product reports

    2011  Volume 28, Issue 2, Page(s) 400–410

    MeSH term(s) Animals ; Bacteria ; Biofouling/prevention & control ; Biological Products/pharmacology ; Biological Products/toxicity ; Fungi ; Invertebrates ; Marine Biology ; Plants ; Quorum Sensing/drug effects ; Seaweed
    Chemical Substances Biological Products
    Language English
    Publishing date 2011-02
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2002546-4
    ISSN 1460-4752 ; 0265-0568
    ISSN (online) 1460-4752
    ISSN 0265-0568
    DOI 10.1039/c0np00034e
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Coronarin D, a Metabolite from the Wild Turmeric, Curcuma aromatica, Promotes the Differentiation of Neural Stem Cells into Astrocytes

    Otsuka, Satoshi / Kawamura, Midori / Fujino, Shutaro / Nakamura, Fumiaki / Arai, Daisuke / Fusetani, Nobuhiro / Nakao, Yoichi

    Journal of agricultural and food chemistry. 2022 Mar. 04, v. 70, no. 10

    2022  

    Abstract: Plants in the genus Curcuma have been widely used as traditional medicines in Asian countries. These plants contain bioactive compounds with neuroprotective properties or activities that increase neural stem cells (NSCs) and neurons. However, bioactive ... ...

    Abstract Plants in the genus Curcuma have been widely used as traditional medicines in Asian countries. These plants contain bioactive compounds with neuroprotective properties or activities that increase neural stem cells (NSCs) and neurons. However, bioactive components in Curcuma that promote the differentiation of NSCs into astrocytes have not yet been reported. Here, the effects of Curcuma extracts on the in vitro differentiation of embryonic stem-cell-derived NSCs were evaluated. The extract of the wild turmeric, Curcuma aromatica, strongly promoted the differentiation of NSCs into astrocytes. Bioassay-guided isolation yielded coronarins C (1) and D (2), as well as (E)-labda-8(17),12-diene-15,16-dial (3) as the bioactive compounds. Coronarin D (2) markedly promoted the differentiation of NSCs into astrocytes up to approximately 4 times (3.64 ± 0.48) and increased the expression level of GFAP at the mRNA and protein level, while compounds 1 and 3 exhibited only weak effects, suggesting that the 15-hydroxy-Δ¹²-γ-lactone moiety is important for bioactivity. Moreover, compound 2 increased the number of pSTAT3-positive cells, suggesting that compound 2 promoted astrocytic differentiation through JAK/STAT signaling pathway.
    Keywords Curcuma aromatica ; astrocytes ; food chemistry ; metabolites ; moieties ; protein content
    Language English
    Dates of publication 2022-0304
    Size p. 3300-3309.
    Publishing place American Chemical Society
    Document type Article
    ZDB-ID 241619-0
    ISSN 1520-5118 ; 0021-8561
    ISSN (online) 1520-5118
    ISSN 0021-8561
    DOI 10.1021/acs.jafc.2c00020
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 1185: Show issues

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  10. Article ; Online: Marine pharmacology in 2018: Marine compounds with antibacterial, antidiabetic, antifungal, anti-inflammatory, antiprotozoal, antituberculosis and antiviral activities; affecting the immune and nervous systems, and other miscellaneous mechanisms of action.

    Mayer, Alejandro M S / Pierce, Marsha L / Howe, Katelyn / Rodríguez, Abimael D / Taglialatela-Scafati, Orazio / Nakamura, Fumiaki / Fusetani, Nobuhiro

    Pharmacological research

    2022  Volume 183, Page(s) 106391

    Abstract: The 2018 marine pharmacology literature review represents a continuation of the previous 11 reviews of a series initiated in 1998. Preclinical marine pharmacology research during 2018 was performed by investigators in 44 countries and contributed novel ... ...

    Abstract The 2018 marine pharmacology literature review represents a continuation of the previous 11 reviews of a series initiated in 1998. Preclinical marine pharmacology research during 2018 was performed by investigators in 44 countries and contributed novel pharmacology for 195 marine compounds. The peer-reviewed marine natural products pharmacology literature reported antibacterial, antifungal, antiprotozoal, antituberculosis, and antiviral activities for 53 compounds, 73 compounds which presented antidiabetic and anti-inflammatory activities as well as affecting the immune and nervous system, while in contrast 69 compounds were reported to show miscellaneous mechanisms of action which may contribute upon further investigation to several pharmacological classes. Thus, in 2018, the preclinical marine natural product pharmacology pipeline continued to report novel pharmacology as well as new lead compounds for the clinical marine pharmaceutical pipeline, which currently contributes to therapeutic strategies for several disease categories.
    MeSH term(s) Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; Antifungal Agents ; Antiprotozoal Agents/pharmacology ; Antiprotozoal Agents/therapeutic use ; Antitubercular Agents/pharmacology ; Antitubercular Agents/therapeutic use ; Antiviral Agents/pharmacology ; Antiviral Agents/therapeutic use ; Biological Products/pharmacology ; Biological Products/therapeutic use ; Hypoglycemic Agents/pharmacology ; Hypoglycemic Agents/therapeutic use ; Marine Biology ; Nervous System
    Chemical Substances Anti-Inflammatory Agents ; Antifungal Agents ; Antiprotozoal Agents ; Antitubercular Agents ; Antiviral Agents ; Biological Products ; Hypoglycemic Agents
    Language English
    Publishing date 2022-08-06
    Publishing country Netherlands
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1003347-6
    ISSN 1096-1186 ; 0031-6989 ; 1043-6618
    ISSN (online) 1096-1186
    ISSN 0031-6989 ; 1043-6618
    DOI 10.1016/j.phrs.2022.106391
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 721: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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