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Article ; Online: Bacterial diversity in water from Xifeng Hot Spring in China.

Wu, Lijuan / Long, Hong / Huang, Shihui / Niu, Xi / Li, Sheng / Yu, Xing / You, Longjiang / Ran, Xueqin / Wang, Jiafu

Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology

2023 Volume 54, Issue 3, Page(s) 1943–1954

Abstract: The Xifeng Hot Spring is one of the eight largest hot springs in China, which is rich in radon gas ... for tourist (SPT) and sewage effluent pool (SEP) in the Xifeng Hot Spring and further analyzed by culture ... from Xifeng Hot Spring. Furthermore, it was found that genus Flavobacterium was susceptible ...

Abstract	The Xifeng Hot Spring is one of the eight largest hot springs in China, which is rich in radon gas and sulphur in karst scenery. Little is known about the microbiota structure in the spring. The water was collected from three sites containing the outlet of spring water discharge site (OWD), spring pool for tourist (SPT) and sewage effluent pool (SEP) in the Xifeng Hot Spring and further analyzed by culture-independent technique and culture-dependent method. A total of 57 phyla were identified from the water samples. The dominate phyla at OWD was Bacteroidetes (46.93%), while it was Proteobacteria in both sites of SEP and SPT with relative richness of 61.9% and 94.9%, respectively. Two bacteria, Deinococcus and Hymenobacter, that confirmed to be radiation-resistant, seven sulphur bacteria and three thermophilic bacteria were detected from Xifeng Hot Spring. Furthermore, it was found that genus Flavobacterium was susceptible to environmental change with abundance of 11 ~ 2825 times higher in OWD than the other two groups. Compared bacteria from the OWD group with that from 14 hot springs in six countries, total 94 unique genera bacteria were found out from the Xifeng Hot Spring including four thiometabolism-related bacteria (Propionispira, Desulforegula, Desulfobacter and Desulfococcus) and the thermophilic bacterium (Symbiobacterium). Using microbial culturing and isolation technology, sixteen strains were isolated from the water samples of three sites. The diversity of microbiota was abundant and variable along with the niche changed in conditions and surroundings. It indicated that numbers of valuable bacteria resources could be explored from the special surroundings of Xifeng Hot Spring.
MeSH term(s)	Hot Springs ; Bacteria/genetics ; China ; Sewage ; Sulfur ; Water
Chemical Substances	Sewage ; Sulfur (70FD1KFU70) ; Water (059QF0KO0R)
Language	English
Publishing date	2023-08-18
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2017175-4
ISSN	1678-4405 ; 1517-8382
ISSN (online)	1678-4405
ISSN	1517-8382
DOI	10.1007/s42770-023-01070-7
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Article ; Online: Study on material basis and anti-hypertensive metabolomics of Zhengan-Xifeng-Tang(ZXT): A comparison between ZXT decoction and granules.

Li, Haichao / Wang, Lihua / Zhang, Hao / Yu, Wenchi / Li, Yunlun / Jiang, Haiqing / Wang, Danyang / Wang, Yu

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

2024 Volume 1236, Page(s) 124063

Abstract: ... complications in cardiovascular disease. The ZXT granules were prepared based on the Zhengan-Xifeng-Tang (ZXT ...

Abstract	High blood pressure is a serious human health problem and one of the leading risk factors for fatal complications in cardiovascular disease. The ZXT granules were prepared based on the Zhengan-Xifeng-Tang (ZXT) decoction. However, the therapeutic effects of ZXT granules on spontaneous hypertension and the metabolic pathways in which they may intervene are unclear. The aim of this study was to investigate the antihypertensive effect of ZXT granules on spontaneously hypertensive rats (SHR) and to analyze the metabolic pathway of intervention through chemical composition characterization, pharmacodynamics, and serum metabolomics analysis. After eight weeks of administration, serum and aortic arch samples were collected for biochemical, histopathology and serum metabolomics analysis to assess the effect of ZXT granules on SHR. The results showed that ZXT granules reduced aortic arch injury and blood pressure in SHR rats. Serum data from rats in each group was collected using LC-MS and 74 potential biomarkers were identified that showed significant differences between the model and control groups. Of these, 18 potential biomarkers were found to be deregulated after intervention with ZXT granules. These 18 potential differential metabolic markers are primarily involved in bile acid biosynthesis, arachidonic acid metabolism pathway, and fatty acid degradation. The results demonstrated that ZXT granules significantly affected blood lipids, aortic arch, and metabolic disorders in SHR rats. ZXT granules offer a new possibility for effective and convenient treatment of hypertensive patients.
MeSH term(s)	Humans ; Rats ; Animals ; Antihypertensive Agents/pharmacology ; Rats, Inbred SHR ; Hypertension/drug therapy ; Metabolomics/methods ; Biomarkers ; Drugs, Chinese Herbal/pharmacology ; Drugs, Chinese Herbal/therapeutic use
Chemical Substances	Antihypertensive Agents ; Biomarkers ; Drugs, Chinese Herbal
Language	English
Publishing date	2024-03-01
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1180823-8
ISSN	1873-376X ; 0378-4347 ; 1570-0232 ; 1387-2273
ISSN (online)	1873-376X
ISSN	0378-4347 ; 1570-0232 ; 1387-2273
DOI	10.1016/j.jchromb.2024.124063
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Article ; Online: Study of Township Construction Land Carrying Capacity and Spatial Pattern Matching in Loess Plateau Hilly and Gully Region: A Case of Xifeng in China.

Zhao, Yirui / Li, Tongsheng / Li, Julin / Song, Mengwei

International journal of environmental research and public health

2022 Volume 19, Issue 23

Abstract: ... territorial space. Taking Xifeng, Gansu Province, China as the research area, this study constructs ...

Abstract	With the acceleration of urbanization, the construction land scale of urban and rural areas is constantly expanding, which leads to contradiction and conflict between territorial development and ecological protection becoming more and more serious. Therefore, as an important unit of county (district), and even urban and rural, development, the study on land resource carrying capacity and the rationality of the development can provide some basis for developing the optimal strategies of differential territorial space. Taking Xifeng, Gansu Province, China as the research area, this study constructs the evaluation index system of township construction land carrying capacity from the three dimensions of ecological protection, natural environment, and social economy. It evaluates the suitability of township construction land by the means of a comprehensive scoring method and discusses the carrying capacity and spatial pattern matching of township construction land based on the suitability evaluation results. The results showed that: (1) the spatial difference of suitability of construction land is obvious, which is higher in the city center than in the surrounding areas; (2) the comprehensive carrying capacity of township construction land is 52.62%, and different townships range from 3.78% to 13.15%. It is different between towns; (3) on the whole, the condition of township construction land is well-developed, and the main distribution forms are flaky, banded, and dotted. (4) There is a positive correlation between spatial matching and carrying capacity. The carrying capacity should be considered in regional development to avoid overdevelopment. It can provide a basis for optimizing the territorial spatial layout, strengthening the coordinated development among townships, and improving the comprehensive township carrying capacity in the Loess Plateau hilly and gully region.
Language	English
Publishing date	2022-12-06
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph192316316
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Article ; Online: Genesis of the Xifeng Low-Temperature Geothermal Field, Guizhou, SW China

Yanyan Li / Ji Dor / Chengjiang Zhang / Guiling Wang / Baojian Zhang / Fangfang Zhang / Yifei Xing

Frontiers in Earth Science, Vol

Constrains From Geology, Element Geochemistry, and D-O Isotopes

2021 Volume 9

Abstract: The Xifeng geothermal field is located in the Yangtze Craton, SW China, and is one of the most ... of the Xifeng geothermal field were analyzed in this study. The ions studies revealed that most samples featured ... the Ca-Mg-HCO3 type, except Xifeng hot springs, and which were characterized by the Ca-Mg-HCO3-SO4 type ...

Abstract	The Xifeng geothermal field is located in the Yangtze Craton, SW China, and is one of the most representative low-temperature geothermal fields in China. Widespread thermal anomalies, hot springs, and geothermal wells have been reported by previous studies. However, the nature and forming mechanisms of the field remain poorly understood. Element geochemical (ions, rare earth elements) and stable isotopic (D, O) composition of hot springs, geothermal fluids, rivers, and cold springs from different locations of the Xifeng geothermal field were analyzed in this study. The ions studies revealed that most samples featured the Ca-Mg-HCO3 type, except Xifeng hot springs, and which were characterized by the Ca-Mg-HCO3-SO4 type. Based on quartz geothermometers, the estimated reservoir temperature was 77°C. The results of stable isotopes (D, O) manifest that the Xifeng geothermal system was recharged by meteoric water at an elevation of 1,583 m from SW to NE. The research of rare earth elements (REE) revealed that their accumulation characteristics and obvious positive Eu anomaly were inherited from host feldspar-bearing reservoir dolomites through water-rock interactions. Combined with these observations, geological setting, and previous studies, it was concluded that the formation of the Xifeng geothermal field resulted from recharge, deep circulation, and secondary rising of the meteoric water along the faults. First, meteoric water infiltrated to depth through faults and crack zones. Second, the deep-infiltrated water was heated by radioactive heat, deep heat, and tectonic frictional heat. Finally, as the warmed-up waters underwent considerable deep circulation in the reservoir, it rose again along the main faults, and mixed with groundwater near the surface. Taken together, we suggest that the Xifeng geothermal system should be assigned as a faults-controlling, and deeply circulating meteoric water of low-temperature category.
Keywords	geology ; element geochemistry ; D-O isotopes ; xifeng ; SW China ; Science ; Q
Subject code	550
Language	English
Publishing date	2021-12-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
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Article ; Online: Herbal medicine (Zhengan Xifeng Decoction) for essential hypertension protocol for a systematic review and meta-analysis.

Huang, Yonglian / Chen, Yanhong / Cai, Hairong / Chen, Dongjie / He, Xiaoming / Li, Zhixiong / Cai, Xiaojing / Peng, Xiaohong / Huang, Yaxiu / Li, Shaoping / Cao, Qifeng / Wang, Ping / Chen, Bojun

Medicine

2019 Volume 98, Issue 6, Page(s) e14292

Abstract: ... as a leading risk factor for cardiocerebrovascular diseases. Zhengan Xifeng Decoction (ZGXFD) has been widely ...

Abstract	Background: Essential hypertension is one of the most common chronic diseases worldwide, as well as a leading risk factor for cardiocerebrovascular diseases. Zhengan Xifeng Decoction (ZGXFD) has been widely used to treat essential hypertension, but there is no systematic review by assessing efficacy and safety of ZGXFD on essential hypertension. Therefore, we aim to perform systematic review and meta-analysis to evaluate the efficacy and safety of ZGXFD in the treatment of essential hypertension. Methods: This systematic review and meta-analysis will be performed by means of electronic databases, including EMBASE, Cochrane Center Registration Controlled trials (Cochrane Library), Web of Science (WOS), World Health Organization International Clinical Trials Registry Platform, PubMed, China Biomedical Literature Database (CBM), China National Knowledge Infrastructure (CNKI), Chinese Scientific Journal Database (VIP), and Wan-fang database. The electronic databases will be searched from their inception to October 2018. This systemic review will include only published English and Chinese articles randomized controlled trials (RTCs) of ZGXFD on essential hypertension. The primary outcome is Efficacy and blood pressure (BP), blood lipid and adverse reactions will be accepted as secondary outcomes. All statistical analyses will be conducted using RevMan V.5.3.5 software. Results: This systematic review and meta-analysis will provide high-quality evidence from several aspects, including for efficacy, blood pressure, blood lipid and adverse effects to evaluate the efficacy and safety of ZGXFD on EHTN. Conclusion: This systematic review will determine whether or not ZGXFD is an effective intervention for essential hypertension.
MeSH term(s)	Drugs, Chinese Herbal/therapeutic use ; Essential Hypertension/drug therapy ; Humans ; Phytotherapy ; Meta-Analysis as Topic ; Systematic Review as Topic
Chemical Substances	Drugs, Chinese Herbal
Language	English
Publishing date	2019-02-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000014292
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Article: [Effects of Chinese herbal medicine Xifeng Capsule on multidrug resistance-associated protein 1 expression in hippocampus and cortex of rats with lithium-pilocarpine-induced epilepsy].

Li, Xin-min / Chen, Hui / Ren, Yan-yan / Lu, Yan-li

Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine

2012 Volume 10, Issue 8, Page(s) 911–917

Abstract: Objective: To study the effects of Xifeng Capsule, a compound traditional Chinese herbal medicine ... Xifeng Capsule, medium-dose Xifeng Capsule, low-dose Xifeng Capsule, high-dose Xifeng Capsule plus ... carbamazepine (CBZ) (combined high-dose group), high-dose Xifeng Capsule plus half dose of CBZ (combined low ...

Abstract	Objective: To study the effects of Xifeng Capsule, a compound traditional Chinese herbal medicine, combined with carbamazepine on spontaneous epileptic seizure induced by lithium and pilocarpine in rats and the expression level of multidrug resistance-associated protein 1 (MRP1). Methods: Lithium and pilocarpine were used to induce epilepsies in rats. All epileptic rats were randomly divided into model, high-dose Xifeng Capsule, medium-dose Xifeng Capsule, low-dose Xifeng Capsule, high-dose Xifeng Capsule plus carbamazepine (CBZ) (combined high-dose group), high-dose Xifeng Capsule plus half dose of CBZ (combined low-dose group) and CBZ groups with 10 rats in each group. And another 10 normal rats served as control. After treating 28 d, immunohistochemical method was used to detect the MRP1 expression in cortex and hippocampus of the epileptic rats. Results: MRP1 expression in hippocampus of the treated groups was higher than that of the normal control group, with wider range and darker positive particles, but was lower than that of the model group. In the cortical areas, the differences between the combined high-dose group or the combined low-dose group and the model group were statistically significant (P<0.05). Regardless of the hippocampus CA1, CA3, gyrus or cortical areas, the influence of high-dose Xifeng Capsule on MRP1 distribution was superior to that of low-dose Xifeng Capsule; Xifeng Capsule combined with CBZ had better effects than low-dose Xifeng Capsule, medium-dose Xifeng Capsule and CBZ used alone (P<0.05). Conclusion: Xifeng Capsule used alone or combined with CBZ can effectively inhibit MRP1 expression in hippocampus and cortex of epileptic rats.
MeSH term(s)	Animals ; Cerebral Cortex/metabolism ; Drugs, Chinese Herbal/pharmacology ; Epilepsy/chemically induced ; Epilepsy/metabolism ; Hippocampus/metabolism ; Lithium Compounds/adverse effects ; Male ; Multidrug Resistance-Associated Proteins/metabolism ; Pilocarpine/adverse effects ; Rats ; Rats, Sprague-Dawley
Chemical Substances	Drugs, Chinese Herbal ; Lithium Compounds ; Multidrug Resistance-Associated Proteins ; Pilocarpine (01MI4Q9DI3) ; multidrug resistance-associated protein 1 (Y49M64GZ4Q)
Language	Chinese
Publishing date	2012-08-09
Publishing country	China
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	2229154-4
ISSN	1672-1977
ISSN	1672-1977
DOI	10.3736/jcim20120812
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Article: [Effects of yanggan xifeng recipe on changes of neurological behavior of rat of Parkinson's model].

Li, W / Cai, D / Chen, X

Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine

2000 Volume 20, Issue 12, Page(s) 920–922

Abstract: Objective: To investigate the effect of Yanggan Xifeng Recipe (YGXFR) for nourishing Liver to calm ...

Abstract	Objective: To investigate the effect of Yanggan Xifeng Recipe (YGXFR) for nourishing Liver to calm down endogenous Wind on neurological behavior of Parkinson's disease (PD) rat model. Methods: PD rat model was established by destroying the substantia nigra condense area (SNc) and ventral tegmental area (VTA) unilaterally with 6-hydroxy dopamine (6-OHDA). The rats for control were injected in the same site with the same dose of normal saline. The animals were randomly divided into 3 groups (7 in each group), the control group, the model group and the TCM treated group. Staircase test and rotation test induced by apomorphine were performed in all groups and compared. Results: The staircase test demonstrated that, after being treated with YGXFR, the food pellets intake were increased compared to model group (P < 0.05), and their rotation induced by apomorphine was lessened (P < 0.01). Conclusion: YGXFR could recover the neurological behavior deficits of PD rat models.
MeSH term(s)	Animals ; Behavior, Animal/drug effects ; Drugs, Chinese Herbal/pharmacology ; Male ; Oxidopamine ; Parkinson Disease, Secondary/chemically induced ; Parkinson Disease, Secondary/psychology ; Random Allocation ; Rats ; Rats, Sprague-Dawley ; Rotation
Chemical Substances	Drugs, Chinese Herbal ; Oxidopamine (8HW4YBZ748)
Language	Chinese
Publishing date	2000-12
Publishing country	China
Document type	English Abstract ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1195456-5
ISSN	1003-5370
ISSN	1003-5370
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Zs.B 2863: Show issues

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Article ; Online: Effects of Chinese herbal medicine Xifeng Capsule on multidrug resistance-associated protein 1 expression in hippocampus and cortex of rats with lithium-pilocarpine-induced epilepsy

Xin-min Li

Journal of Integrative Medicine (JIM), Vol 10, Iss 8, Pp 911-

2012 Volume 917

Abstract: OBJECTIVE: To study the effects of Xifeng Capsule, a compound traditional Chinese herbal medicine ... Xifeng Capsule, medium-dose Xifeng Capsule, low-dose Xifeng Capsule, high-dose Xifeng Capsule plus ... carbamazepine (CBZ) (combined high-dose group), high-dose Xifeng Capsule plus half dose of CBZ (combined low ...

Abstract	OBJECTIVE: To study the effects of Xifeng Capsule, a compound traditional Chinese herbal medicine, combined with carbamazepine on spontaneous epileptic seizure induced by lithium and pilocarpine in rats and the expression level of multidrug resistance-associated protein 1 (MRP1).METHODS: Lithium and pilocarpine were used to induce epilepsies in rats. All epileptic rats were randomly divided into model, high-dose Xifeng Capsule, medium-dose Xifeng Capsule, low-dose Xifeng Capsule, high-dose Xifeng Capsule plus carbamazepine (CBZ) (combined high-dose group), high-dose Xifeng Capsule plus half dose of CBZ (combined low-dose group) and CBZ groups with 10 rats in each group. And another 10 normal rats served as control. After treating 28 d, immunohistochemical method was used to detect the MRP1 expression in cortex and hippocampus of the epileptic rats.RESULTS: MRP1 expression in hippocampus of the treated groups was higher than that of the normal control group, with wider range and darker positive particles, but was lower than that of the model group. In the cortical areas, the differences between the combined high-dose group or the combined low-dose group and the model group were statistically significant (P<0.05). Regardless of the hippocampus CA1, CA3, gyrus or cortical areas, the influence of high-dose Xifeng Capsule on MRP1 distribution was superior to that of low-dose Xifeng Capsule; Xifeng Capsule combined with CBZ had better effects than low-dose Xifeng Capsule, medium-dose Xifeng Capsule and CBZ used alone (P<0.05).CONCLUSION: Xifeng Capsule used alone or combined with CBZ can effectively inhibit MRP1 expression in hippocampus and cortex of epileptic rats.
Keywords	Medicine (General) ; R5-920 ; Medicine ; R ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Subject code	616
Language	English
Publishing date	2012-08-01T00:00:00Z
Publisher	Journal of Chinese Integrative Medicine Press
Document type	Article ; Online
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Article: [Effect of Pinggan Xifeng decoction on hippocampal mitochondrial membrane potential after intracerebral hemorrhage in rat brain].

Tan, Yong / Liang, Qing-Hua / Li, Xia-Ling

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences

2004 Volume 29, Issue 1, Page(s) 35–38

Abstract: Objective: To observe the effects of Pinggan Xifeng decoction (PGXFD) on the change ...

Abstract	Objective: To observe the effects of Pinggan Xifeng decoction (PGXFD) on the change of mitochondrial membrane potential (MMP) after intracerebral hemorrhage (ICH) injury in rat brain and to explore the mechanism of PGXF decoction in the treatment of ICH. Methods: VII type collagenase was stereotaxically injected into the globas pallidus of rats and spectrofluorometer was used to detect the fluorescence value of mitochondrial suspension. The neurobehavioral scores were used to evaluate the neurological defect. Results: Neurological function defects were seen after ICH in rats and PGXFD decreased the neurological grades. The MMP of rats with ICH was reduced significantly 4 hours after the operation, peaking at 1 d and was higher at 3 d and 7 d than that of the sham group . MMP in the PGXFD group was obviously higher than that in the control group at 1 d, 3 d, and 7 d. Conclusion: MMP decreased in rats suffering from ICH. PGXFD can markedly depress the decreation of MMP.
MeSH term(s)	Animals ; Cerebral Hemorrhage/drug therapy ; Cerebral Hemorrhage/metabolism ; Cerebral Hemorrhage/physiopathology ; Drugs, Chinese Herbal/pharmacology ; Drugs, Chinese Herbal/therapeutic use ; Female ; Hippocampus/metabolism ; Hippocampus/physiopathology ; Male ; Membrane Potentials ; Mitochondria/physiology ; Random Allocation ; Rats ; Rats, Sprague-Dawley
Chemical Substances	Drugs, Chinese Herbal
Language	Chinese
Publishing date	2004-02
Publishing country	China
Document type	English Abstract ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2168533-2
ISSN	1672-7347
ISSN	1672-7347
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Article: A superior seedless mutant clone of 'Jing' Orange 'Xifeng No. 1'

Jiang, J / Li, D / Fu, D

Acta horticulturae. July 1995. (403)

1995

Keywords	Citrus sinensis ; clones ; seedless varieties
Language	English
Dates of publication	1995-07
Size	p. 96.
Document type	Article
Note	Paper presented at the International Symposium on Cultivar Improvement of Horticultural Crops. Part II: Fruit Crops, September 6-10, 1993, Beijing, China.
ISSN	0567-7572
Database	NAL-Catalogue (AGRICOLA)

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