LIVIVO - Search results -

Search results

Result 1 - 10 of total 2076

Search options

Article: Phytohormonal Regulation Through Protein S-Nitrosylation Under Stress.

Pande, Anjali / Mun, Bong Gyu / Rahim, Waqas / Khan, Murtaza / Lee, Da Sol / Lee, Geun Mo / Al Azzawi, Tiba Nazar Ibrahim / Hussain, Adil / Kim, Chang Kil / Yun, Byung Wook

Frontiers in plant science

2022 Volume 13, Page(s) 865542

Abstract: ... post-translational modifications (PTMs) under basal as well as induced conditions. Protein S-nitrosylation is the most prominent ... of a NO moiety to the sulfhydryl group of cysteine (Cys) molecule(s) on a target protein to form S ... nitrosothiols. This process may involve either direct S-nitrosylation or indirect S-nitrosylation followed ...

Abstract	The liaison between Nitric oxide (NO) and phytohormones regulates a myriad of physiological processes at the cellular level. The interaction between NO and phytohormones is mainly influenced by NO-mediated post-translational modifications (PTMs) under basal as well as induced conditions. Protein S-nitrosylation is the most prominent and widely studied PTM among others. It is the selective but reversible redox-based covalent addition of a NO moiety to the sulfhydryl group of cysteine (Cys) molecule(s) on a target protein to form S-nitrosothiols. This process may involve either direct S-nitrosylation or indirect S-nitrosylation followed by transfer of NO group from one thiol to another (transnitrosylation). During S-nitrosylation, NO can directly target Cys residue (s) of key genes involved in hormone signaling thereby regulating their function. The phytohormones regulated by NO in this manner includes abscisic acid, auxin, gibberellic acid, cytokinin, ethylene, salicylic acid, jasmonic acid, brassinosteroid, and strigolactone during various metabolic and physiological conditions and environmental stress responses. S-nitrosylation of key proteins involved in the phytohormonal network occurs during their synthesis, degradation, or signaling roles depending upon the response required to maintain cellular homeostasis. This review presents the interaction between NO and phytohormones and the role of the canonical NO-mediated post-translational modification particularly, S-nitrosylation of key proteins involved in the phytohormonal networks under biotic and abiotic stresses.
Language	English
Publishing date	2022-03-24
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2613694-6
ISSN	1664-462X
ISSN	1664-462X
DOI	10.3389/fpls.2022.865542
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: An ecostylistic analysis of selected extracts from Michael Punke’s novel The Revenant

Zahraa Adnan Mohamed / Eman Adil Jaafar

Cogent Arts & Humanities, Vol 10, Iss

2023 Volume 1

Abstract: AbstractThis article presents an ecostylistic analysis of selected extracts from Michael Punke’s ... Matthiessen, 2014[1985]) and Zurru’s (2017) approach is followed. Moreover, the study presents a qualitative ... that nature acts as the main character’s savior and a threat to his life; it also demonstrates how nature ...

Abstract	AbstractThis article presents an ecostylistic analysis of selected extracts from Michael Punke’s novel The Revenant (2002). The aims of the study are achieved in terms of an eclectic methodological framework. The study aims at revealing the power hierarchy created in the selected texts between human and non-human participants. Also, it aims to show how the elements of nature affect the survival of humans in the fictional context by identifying the ecostylistic features in the literary text. A close ecostylistic reading of six selected extracts from the novel using Systemic Functional Grammar (SFG) tools (Halliday & Matthiessen, 2014[1985]) and Zurru’s (2017) approach is followed. Moreover, the study presents a qualitative investigation of stylistic elements such as foregrounded features and deviated language patterns. Thus, conducting an ecostylistic analysis of the chosen passages, and, demonstrating how the author portrays the environment with all its elements as an effective participant helps to appreciate nature. The findings show that nature acts as the main character’s savior and a threat to his life; it also demonstrates how nature works as a powerful active participant in portraying the events of the novel.
Keywords	ecostylistics ; fiction ; foregrounding ; SFG ; stylistics analysis ; transitivity processes ; Fine Arts ; N ; Arts in general ; NX1-820 ; General Works ; A ; History of scholarship and learning. The humanities ; AZ20-999
Subject code	820
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	Taylor & Francis Group
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Combined metabolic activators improve cognitive functions in Alzheimer’s disease patients

Burak Yulug / Ozlem Altay / Xiangyu Li / Lutfu Hanoglu / Seyda Cankaya / Simon Lam / Halil Aziz Velioglu / Hong Yang / Ebru Coskun / Ezgi Idil / Rahim Nogaylar / Ahmet Ozsimsek / Cemil Bayram / Ismail Bolat / Sena Oner / Ozlem Ozdemir Tozlu / Mehmet Enes Arslan / Ahmet Hacimuftuoglu / Serkan Yildirim /

Muhammad Arif / Saeed Shoaie / Cheng Zhang / Jens Nielsen / Hasan Turkez / Jan Borén / Mathias Uhlén / Adil Mardinoglu

Translational Neurodegeneration, Vol 12, Iss 1, Pp 1-

a randomised, double-blinded, placebo-controlled phase-II trial

2023 Volume 23

Abstract: Abstract Background Alzheimer’s disease (AD) is associated with metabolic abnormalities linked ...

Abstract	Abstract Background Alzheimer’s disease (AD) is associated with metabolic abnormalities linked to critical elements of neurodegeneration. We recently administered combined metabolic activators (CMA) to the AD rat model and observed that CMA improves the AD-associated histological parameters in the animals. CMA promotes mitochondrial fatty acid uptake from the cytosol, facilitates fatty acid oxidation in the mitochondria, and alleviates oxidative stress. Methods Here, we designed a randomised, double-blinded, placebo-controlled phase-II clinical trial and studied the effect of CMA administration on the global metabolism of AD patients. One-dose CMA included 12.35 g L-serine (61.75%), 1 g nicotinamide riboside (5%), 2.55 g N-acetyl-L-cysteine (12.75%), and 3.73 g L-carnitine tartrate (18.65%). AD patients received one dose of CMA or placebo daily during the first 28 days and twice daily between day 28 and day 84. The primary endpoint was the difference in the cognitive function and daily living activity scores between the placebo and the treatment arms. The secondary aim of this study was to evaluate the safety and tolerability of CMA. A comprehensive plasma metabolome and proteome analysis was also performed to evaluate the efficacy of the CMA in AD patients. Results We showed a significant decrease of AD Assessment Scale-cognitive subscale (ADAS-Cog) score on day 84 vs day 0 (P = 0.00001, 29% improvement) in the CMA group. Moreover, there was a significant decline (P = 0.0073) in ADAS-Cog scores (improvement of cognitive functions) in the CMA compared to the placebo group in patients with higher ADAS-Cog scores. Improved cognitive functions in AD patients were supported by the relevant alterations in the hippocampal volumes and cortical thickness based on imaging analysis. Moreover, the plasma levels of proteins and metabolites associated with NAD + and glutathione metabolism were significantly improved after CMA treatment. Conclusion Our results indicate that treatment of AD patients with CMA can lead to ...
Keywords	Alzheimer’s disease ; Combined metabolic activators ; Multi-omics ; Systems biology ; Systems medicine ; Neurology. Diseases of the nervous system ; RC346-429
Subject code	610
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: S-citalopram imprinted monolithic columns for capillary electrochromatography enantioseparations.

Derazshamshir, Ali / Göktürk, Ilgım / Yılmaz, Fatma / Denizli, Adil

Electrophoresis

2021 Volume 42, Issue 24, Page(s) 2672–2682

Abstract: ... antidepressant drug, R,S-citalopram (R,S-CIT) in aqueous solution by CEC system combining the advantages ... of S-citalopram (S-CIT) for the first time. S-CIT was selectively separated from the aqueous solution ... Morphology of the molecularly imprinted (MIP S-CIT) and non-imprinted (NIP S-CIT) monolithic capillary ...

Abstract	In this study, the molecular imprinting method was used to separate enantiomeric forms of chiral antidepressant drug, R,S-citalopram (R,S-CIT) in aqueous solution by CEC system combining the advantages of capillary electrophoresis (CE) and high-performance liquid chromatography (HPLC). For that, an amino acid-based molecularly imprinted monolithic capillary column was designed and used as a stationary phase for selective separation of S-citalopram (S-CIT) for the first time. S-CIT was selectively separated from the aqueous solution containing the other enantiomeric form of R-CIT, which is the same in size and shape as the template molecule. Morphology of the molecularly imprinted (MIP S-CIT) and non-imprinted (NIP S-CIT) monolithic capillary columns was observed by scanning electron microscopy. Imprinting efficiency of MIP S-CIT monolithic capillary column used for selective S-CIT separation was verified by comparing with NIP S-CIT and calculated imprinting factor (I.F:1.81) proved the high selectivity of the MIP S-CIT for S-CIT. Cavities formed for S-CIT form enabled selective (α = 2.08) separation of the target molecule from the other enantiomeric R-CIT form. Separation was achieved in a short period of 10 min, with the electrophoretic mobility of 7.68 × 10
MeSH term(s)	Capillary Electrochromatography ; Citalopram ; Molecular Imprinting ; Reproducibility of Results ; Stereoisomerism
Chemical Substances	Citalopram (0DHU5B8D6V)
Language	English
Publishing date	2021-09-12
Publishing country	Germany
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	619001-7
ISSN	1522-2683 ; 0173-0835
ISSN (online)	1522-2683
ISSN	0173-0835
DOI	10.1002/elps.202100222
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 1868: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Valuing the Recreational Uses of Pakistan’s Wetlands

Iftikhar Hussain Adil / Ali Dehlavi

NUST Journal of Social Sciences and Humanities, Vol 3, Iss

An Application of the Travel Cost Method

2021 Volume 2

Abstract: The Keenjhar Lake, Pakistan’s largest freshwater lake and a Ramsar site, is located in the Lower ...

Abstract	The Keenjhar Lake, Pakistan’s largest freshwater lake and a Ramsar site, is located in the Lower Indus Basin of the Indus Ecoregion. Global 200, which scientifically ranks outstanding terrestrial and aquatic ecosystems in 238 ecoregions worldwide, the Indus Ecoregion is one of the 40 priority Ecoregions. This study uses a single-site truncated count data travel cost method to estimate the access values of visitors to Keenjhar Lake. Policy makers may use these estimates on the recreational value of the lake to assess the returns on conservation investments. A basic version of the model applied to a subset of visitors using charter transportation allows analysis of impacts on welfare measurement from altering assumptions about embarkation points. This study finds the assumption that this category of visitor does not incur travel and time costs before boarding charter transport to be both unrealistic and simplifying, leading in turn to an underestimate of consumer surplus values. The strongest argument in favour of revising data collection and processing strategies in this regard is perhaps the finding that shared and rented transportation is common in developing countries, while cost coefficients tend to figure prominently in welfare measurement irrespective of the functional form.
Keywords	Travel Cost Method ; Truncated Count Data Model ; Ecotourism ; Keenjhar Lake ; Social Sciences ; H
Subject code	380
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	National University of Sciences and Technology
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Valuing the Recreational Uses of Pakistan’s Wetlands

Iftikhar Hussain Adil / Ali Dehlavi

NUST Journal of Social Sciences and Humanities, Vol 3, Iss

An Application of the Travel Cost Method

2021 Volume 2

Abstract: The Keenjhar Lake, Pakistan’s largest freshwater lake and a Ramsar site, is located in the Lower ...

Abstract	The Keenjhar Lake, Pakistan’s largest freshwater lake and a Ramsar site, is located in the Lower Indus Basin of the Indus Ecoregion. Global 200, which scientifically ranks outstanding terrestrial and aquatic ecosystems in 238 ecoregions worldwide, the Indus Ecoregion is one of the 40 priority Ecoregions. This study uses a single-site truncated count data travel cost method to estimate the access values of visitors to Keenjhar Lake. Policy makers may use these estimates on the recreational value of the lake to assess the returns on conservation investments. A basic version of the model applied to a subset of visitors using charter transportation allows analysis of impacts on welfare measurement from altering assumptions about embarkation points. This study finds the assumption that this category of visitor does not incur travel and time costs before boarding charter transport to be both unrealistic and simplifying, leading in turn to an underestimate of consumer surplus values. The strongest argument in favour of revising data collection and processing strategies in this regard is perhaps the finding that shared and rented transportation is common in developing countries, while cost coefficients tend to figure prominently in welfare measurement irrespective of the functional form.
Keywords	Travel Cost Method ; Truncated Count Data Model ; Ecotourism ; Keenjhar Lake ; Social Sciences ; H
Subject code	380
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	National University of Sciences and Technology
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Author`s Reply.

Bayramoğlu, Adil / Taşolar, Hakan / Otlu, Yılmaz Ömür

Anatolian journal of cardiology

2016 Volume 16, Issue 7, Page(s) 549

Language	English
Publishing date	2016
Publishing country	Turkey
Document type	Letter ; Comment
ISSN	2149-2271
ISSN (online)	2149-2271
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: A Novel RHS1 Locus in Rice Attributes Seed-Pod Shattering by the Regulation of Endogenous S-Nitrosothiols.

Mun, Bong-Gyu / Shahid, Muhammad / Lee, Gang Sub / Hussain, Adil / Yun, Byung-Wook

International journal of molecular sciences

2022 Volume 23, Issue 21

Abstract: Seed or pod shattering in rice ( ...

Abstract	Seed or pod shattering in rice (
MeSH term(s)	Oryza/genetics ; Quantitative Trait Loci ; Nitric Oxide ; Seeds/genetics ; S-Nitrosothiols
Chemical Substances	Nitric Oxide (31C4KY9ESH) ; S-Nitrosothiols
Language	English
Publishing date	2022-10-30
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms232113225
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Simulation of carbon dioxide mineralization and its effect on fault leakage rates in the South Georgia rift basin, southeastern U.S.

Alshammari, Adil / Lakshmi, Venkat / Brantley, Duke / Knapp, Camelia C / Knapp, James H

Heliyon

2022 Volume 8, Issue 6, Page(s) e09635

Abstract: Over the past few decades, measured levels of atmospheric carbon dioxide have substantially increased. One of the ways to limit the adverse impacts of increased carbon dioxide concentrations is to capture and store it inside Earth's subsurface, a process ...

Abstract	Over the past few decades, measured levels of atmospheric carbon dioxide have substantially increased. One of the ways to limit the adverse impacts of increased carbon dioxide concentrations is to capture and store it inside Earth's subsurface, a process known as CO
Language	English
Publishing date	2022-06-07
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2022.e09635
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Dynamics of Anti-S IgG Antibodies Titers after the Second Dose of COVID-19 Vaccines in the Manual and Craft Worker Population of Qatar.

Bansal, Devendra / Atia, Hassan / Al Badr, Mashael / Nour, Mohamed / Abdulmajeed, Jazeel / Hasan, Amal / Al-Hajri, Noora / Ahmed, Lina / Ibrahim, Rumissa / Zamel, Reham / Mohamed, Almuthana / Pattalaparambil, Hamad / Daraan, Faisal / Chaudhry, Adil / Oraby, Sahar / El-Saleh, Sahar / El-Shafie, Sittana S / Al-Farsi, Affra Faiz / Paul, Jiji /

Ismail, Ahmed / Al-Romaihi, Hamad Eid / Al-Thani, Mohammed Hamad / Doi, Suhail A R / Zughaier, Susu M / Cyprian, Farhan / Farag, Elmobashar / Farooqui, Habib Hasan

Vaccines

2023 Volume 11, Issue 3

Abstract: ... evidence on long-term anti-S IgG antibody titers and their dynamics in individuals who have completed ... vaccines BNT162b2/Comirnaty, mRNA-1273, ChAdOx1-S/Covishield, COVID-19 Vaccine Janssen/Johnson, or BBIBP ... the time from the last dose of the primary vaccination schedule to the time by which anti-S IgG antibody ...

Abstract	There is limited seroepidemiological evidence on the magnitude and long-term durability of antibody titers of mRNA and non-mRNA vaccines in the Qatari population. This study was conducted to generate evidence on long-term anti-S IgG antibody titers and their dynamics in individuals who have completed a primary COVID-19 vaccination schedule. A total of 300 male participants who received any of the following vaccines BNT162b2/Comirnaty, mRNA-1273, ChAdOx1-S/Covishield, COVID-19 Vaccine Janssen/Johnson, or BBIBP-CorV or Covaxin were enrolled in our study. All sera samples were tested by chemiluminescent microparticle immunoassay (CMIA) for the quantitative determination of IgG antibodies to SARS-CoV-2, receptor-binding domain (RBD) of the S1 subunit of the spike protein of SARS-CoV-2. Antibodies against SARS-CoV-2 nucleocapsid (SARS-CoV-2 N-protein IgG) were also determined. Kaplan-Meier survival curves were used to compare the time from the last dose of the primary vaccination schedule to the time by which anti-S IgG antibody titers fell into the lowest quartile (range of values collected) for the mRNA and non-mRNA vaccines. Participants vaccinated with mRNA vaccines had higher median anti-S IgG antibody titers. Participants vaccinated with the mRNA-1273 vaccine had the highest median anti-S-antibody level of 13,720.9 AU/mL (IQR 6426.5 to 30,185.6 AU/mL) followed by BNT162b2 (median, 7570.9 AU/mL; IQR, 3757.9 to 16,577.4 AU/mL); while the median anti-S antibody titer for non-mRNA vaccinated participants was 3759.7 AU/mL (IQR, 2059.7-5693.5 AU/mL). The median time to reach the lowest quartile was 3.53 months (IQR, 2.2-4.5 months) and 7.63 months (IQR, 6.3-8.4 months) for the non-mRNA vaccine recipients and Pfizer vaccine recipients, respectively. However, more than 50% of the Moderna vaccine recipients did not reach the lowest quartile by the end of the follow-up period. This evidence on anti-S IgG antibody titers should be considered for informing decisions on the durability of the neutralizing activity and thus protection against infection after the full course of primary vaccination in individuals receiving different type (mRNA verus non-mRNA) vaccines and those with natural infection.
Language	English
Publishing date	2023-02-21
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2703319-3
ISSN	2076-393X
ISSN	2076-393X
DOI	10.3390/vaccines11030496
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

To top

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito