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  1. Article ; Online: Shift of N-MYC Oncogene Expression in AML Patients Carrying the FLT3-ITD Mutation.

    Bogdanov, Konstantin / Kudryavtseva, Ekaterina / Fomicheva, Yulia / Churkina, Irina / Lomaia, Elza / Girshova, Larisa / Osipov, Yuri / Zaritskey, Andrey

    Pathophysiology : the official journal of the International Society for Pathophysiology

    2023  Volume 30, Issue 3, Page(s) 296–313

    Abstract: Mutations in ... ...

    Abstract Mutations in the
    Language English
    Publishing date 2023-08-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1212740-1
    ISSN 1873-149X ; 0928-4680
    ISSN (online) 1873-149X
    ISSN 0928-4680
    DOI 10.3390/pathophysiology30030024
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  2. Article ; Online: Fluorinated Unsymmetrical N,N'-Diaryl Imidazolium Salts-New Functionalized NHC-Ligand Precursors.

    Topchiy, Maxim A / Zotova, Maria A / Masoud, Salekh M / Mailyan, Artur K / Ananyev, Ivan V / Nefedov, Sergey E / Asachenko, Andrey F / Osipov, Sergey N

    Chemistry (Weinheim an der Bergstrasse, Germany)

    2017  Volume 23, Issue 27, Page(s) 6663–6674

    Abstract: An efficient and scaled-up synthesis of the imidazol-2-ylidene-based unsymmetrical NHC precursors bearing the sterically demanding hexafluoroisopropylalkoxy group [( ... ...

    Abstract An efficient and scaled-up synthesis of the imidazol-2-ylidene-based unsymmetrical NHC precursors bearing the sterically demanding hexafluoroisopropylalkoxy group [(CF
    Language English
    Publishing date 2017-05-11
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1478547-x
    ISSN 1521-3765 ; 0947-6539
    ISSN (online) 1521-3765
    ISSN 0947-6539
    DOI 10.1002/chem.201700624
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  3. Article: Catalyst-Free Synthesis of Chromane-Type N,O-Acetals via Intramolecular Addition of Phenols to Enamines

    Osyanin, Vitaly A. / Osipov, Dmitry V. / Melnikova, Irina V. / Korzhenko, Kirill S. / Semenova, Irina A. / Klimochkin, Yuri N.

    Synthesis

    2020  Volume 52, Issue 23, Page(s) 3604–3621

    Abstract: ... The obtained semicyclic N,O-acetals were applied as useful precursors for the synthesis of other chromanes. ...

    Abstract A new strategy to 2-aminochromanes through catalyst-free cascade reaction of 3-trifluoroacetyl-4 H -chromenes and 4 H -chromene-3-carbaldehydes with cyclic secondary amines is presented. The reaction proceeds through subsequent 1,4- and 1,2-additions of amine, bimolecular elimination of trifluoroacetamide or formamide, and 6- exo trig cyclization. The latter stage is a very rare example of addition of phenols to enamines. The obtained semicyclic N,O-acetals were applied as useful precursors for the synthesis of other chromanes.
    Keywords chromanes ; 4 ; -chromenes ; cascade reactions ; enamines ; cyclic secondary amines ; N,O-acetals
    Language English
    Publishing date 2020-07-27
    Publisher © Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2033062-5
    ISSN 1437-210X ; 0039-7881
    ISSN (online) 1437-210X
    ISSN 0039-7881
    DOI 10.1055/s-0040-1707209
    Database Thieme publisher's database

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  4. Article ; Online: Analysis of the p-i-n-structures Electrophysical Characteristics Influence on the Spectral Characteristics Sensitivity

    V.N. Murashev / S.Yu. Yurchuk / S.A. Legotin / V.P. Yaromskiy / Yu.V. Osipov / V.P. Astahov / D.S. El’nikov / S.I. Didenko / O.I. Rabinovich / K.A. Kuz’mina

    Journal of Nano- and Electronic Physics, Vol 7, Iss 2, Pp 02023-1-02023-

    2015  Volume 5

    Abstract: In this paper the simulation of the silicon p-i-n-photodiodes spectral sensitivity characteristics ...

    Abstract In this paper the simulation of the silicon p-i-n-photodiodes spectral sensitivity characteristics was carried out. The analysis of the semiconductor material characteristics (the doping level, lifetime, surface recombination velocity), the construction and operation modes on the photosensitive structures characteristics in order to optimize them were investigated.
    Keywords Silicon p-i-n-photodiode characteristics simulation ; Spectral sensitivity ; Optimization design of photodetector ; Electricity and magnetism ; QC501-766 ; Physics ; QC1-999 ; Science ; Q
    Language English
    Publishing date 2015-06-01T00:00:00Z
    Publisher Sumy State University
    Document type Article ; Online
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  5. Article ; Online: The Spectral Sensitivity Characteristics Simulation of the Silicon p-i-n-structure with High Resistance

    S.A. Legotin / V.N. Murashev / S.Yu. Yurchuk / V.P. Yaromskiy / V.P. Astahov / K.A. Kuz’mina / O.I. Rabinovich / D.S. El’nikov / U.V. Osipov / A.A. Krasnov / S.I. Didenko

    Journal of Nano- and Electronic Physics, Vol 7, Iss 4, Pp 04017-1-04017-

    2015  Volume 2

    Abstract: ... of the high-resistance "well" thickness in the silicon p-i-n-diode spectral response are discussed ...

    Abstract In the paper a simulation program for photovoltaic parameters of semiconductor devices and results of their investigation are presented. The results of the program usage based on an example of calculating the influence of the high-resistance "well" thickness in the silicon p-i-n-diode spectral response are discussed. For the accuracy of the program estimation it was compared the theoretical spectral characteristics of a silicon PIN-diode 5 kOhm substrate with the experimental data.
    Keywords Silicon p-i-n structure ; Design optimizatio ; Electricity and magnetism ; QC501-766 ; Physics ; QC1-999 ; Science ; Q
    Language English
    Publishing date 2015-12-01T00:00:00Z
    Publisher Sumy State University
    Document type Article ; Online
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  6. Book ; Online: n-Level Graph Partitioning

    Osipov, Vitaly / Sanders, Peter

    2010  

    Abstract: We present a multi-level graph partitioning algorithm based on the extreme idea to contract only a single edge on each level of the hierarchy. This obviates the need for a matching algorithm and promises very good partitioning quality since there are ... ...

    Abstract We present a multi-level graph partitioning algorithm based on the extreme idea to contract only a single edge on each level of the hierarchy. This obviates the need for a matching algorithm and promises very good partitioning quality since there are very few changes between two levels. Using an efficient data structure and new flexible ways to break local search improvements early, we obtain an algorithm that scales to large inputs and produces the best known partitioning results for many inputs. For example, in Walshaw's well known benchmark tables we achieve 155 improvements dominating the entries for large graphs.
    Keywords Computer Science - Data Structures and Algorithms
    Publishing date 2010-04-22
    Publishing country us
    Document type Book ; Online
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  7. Article ; Online: Changes in the Number of Residual γH2AX Foci in Ki-67-Positive and Ki-67-Negative Human Fibroblasts Irradiated with X-Rays in Doses of 2-10 Gy.

    Vorobyeva, N Yu / Osipov, A A / Chigasova, A K / Yashkina, E I / Osipov, A N

    Bulletin of experimental biology and medicine

    2023  Volume 175, Issue 4, Page(s) 450–453

    Abstract: We studied changes in the number of residual γH2AX foci in cultured human fibroblasts with different expression of the cell proliferation marker protein Ki-67 24, 48, and 72 h after exposure to X-ray radiation in doses of 2-10 Gy. It was shown that, ... ...

    Abstract We studied changes in the number of residual γH2AX foci in cultured human fibroblasts with different expression of the cell proliferation marker protein Ki-67 24, 48, and 72 h after exposure to X-ray radiation in doses of 2-10 Gy. It was shown that, regardless of the expression of Ki-67, the number of residual γH2AX foci in irradiated cells linearly depends on the absorbed dose of X-ray radiation. However, the quantitative yield of residual γH2AX foci per unit of the absorbed dose in Ki-67
    MeSH term(s) Humans ; X-Rays ; Ki-67 Antigen/genetics ; Ki-67 Antigen/metabolism ; Histones/genetics ; Histones/metabolism ; DNA Repair ; Dose-Response Relationship, Radiation ; Fibroblasts/metabolism
    Chemical Substances Ki-67 Antigen ; Histones
    Language English
    Publishing date 2023-09-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 390407-6
    ISSN 1573-8221 ; 0007-4888 ; 0365-9615
    ISSN (online) 1573-8221
    ISSN 0007-4888 ; 0365-9615
    DOI 10.1007/s10517-023-05883-2
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  8. Article ; Online: DNIC is a Structure Providing Specificity of Physiological Effects of NO.

    Titov, V Yu / Dolgorukova, A M / Osipov, A N / Kochish, I I

    Bulletin of experimental biology and medicine

    2024  Volume 176, Issue 2, Page(s) 160–164

    Abstract: Metabolism of nitric oxide (NO) donors: dinitrosyl iron complexes (DNIC), nitrosothiols (RSNO), and nitroprusside was studied on a chick embryo model. The obtained results give reason to assume that DNIC constituting the main pool of nitroso compounds in ...

    Abstract Metabolism of nitric oxide (NO) donors: dinitrosyl iron complexes (DNIC), nitrosothiols (RSNO), and nitroprusside was studied on a chick embryo model. The obtained results give reason to assume that DNIC constituting the main pool of nitroso compounds in the vast majority of tissues are NO donors immediately interacting with the physiological target of NO, and other NO donors can perform this function after their transformation into DNIC. NO is released from DNIC not spontaneously, but under a joint influence of a factor destroying the complex and a target having chemical affinity for NO. A similar mechanism is apparently implicated in NO passage through the cell membrane.
    MeSH term(s) Chick Embryo ; Animals ; Nitric Oxide/metabolism ; Nitrogen Oxides/metabolism ; Nitric Oxide Donors/pharmacology ; Nitric Oxide Donors/metabolism ; Iron/chemistry
    Chemical Substances Nitric Oxide (31C4KY9ESH) ; dinitrosyl iron complex (68586-27-6) ; Nitrogen Oxides ; Nitric Oxide Donors ; Iron (E1UOL152H7)
    Language English
    Publishing date 2024-01-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 390407-6
    ISSN 1573-8221 ; 0007-4888 ; 0365-9615
    ISSN (online) 1573-8221
    ISSN 0007-4888 ; 0365-9615
    DOI 10.1007/s10517-024-05987-3
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  9. Article: Synthesis of new quinazoline-containing hydroxamic acids as potential HDAC/VEGFR inhibitors. Unusual rearrangements with pyrrolidone ring opening and dehydration of 3-N-hydroxyquinazoline fragment containing tetracycles

    Kolotaev, Anton V / Khachatryan, Derenik S / Matevosyan, Karine R / Osipov, Vasiliy N

    Tetrahedron letters. 2019 Dec. 19, v. 60, no. 51

    2019  

    Abstract: Synthesis pathways were developed and new hydroxamic acids were obtained as potential inhibitors of HDAC/VEGFR2, including tetracycles containing quinazolinone fragment as a “cap”. Further biological testing of the obtained compounds will give an ... ...

    Abstract Synthesis pathways were developed and new hydroxamic acids were obtained as potential inhibitors of HDAC/VEGFR2, including tetracycles containing quinazolinone fragment as a “cap”. Further biological testing of the obtained compounds will give an opportunity to estimate the real prospects of the chosen research direction.
    Keywords chemical reactions ; chemical structure ; hydroxamic acids ; pyrrolidones ; vascular endothelial growth factor receptor-2
    Language English
    Dates of publication 2019-1219
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 204287-3
    ISSN 1873-3581 ; 0040-4039
    ISSN (online) 1873-3581
    ISSN 0040-4039
    DOI 10.1016/j.tetlet.2019.151315
    Database NAL-Catalogue (AGRICOLA)

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  10. Book ; Online: From prediction markets to interpretable collective intelligence

    Osipov, Alexey V. / Osipov, Nikolay N.

    2022  

    Abstract: We outline how to create a mechanism that provides an optimal way to elicit, from an arbitrary group of experts, the probability of the truth of an arbitrary logical proposition together with collective information that has an explicit form and ... ...

    Abstract We outline how to create a mechanism that provides an optimal way to elicit, from an arbitrary group of experts, the probability of the truth of an arbitrary logical proposition together with collective information that has an explicit form and interprets this probability. Namely, we provide strong arguments for the possibility of the development of a self-resolving prediction market with play money that incentivizes direct information exchange between experts. Such a system could, in particular, motivate simultaneously many experts to collectively solve scientific or medical problems in a very efficient manner. We also note that in our considerations, experts are not assumed to be Bayesian.

    Comment: 41 pages, 3 figures, 3 tables
    Keywords Computer Science - Computer Science and Game Theory ; Computer Science - Artificial Intelligence ; Computer Science - Information Theory ; Computer Science - Multiagent Systems ; Economics - Econometrics
    Subject code 160
    Publishing date 2022-04-28
    Publishing country us
    Document type Book ; Online
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