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  1. Article ; Online: Radar detection of pedestrian-induced vibrations on Michelangelo's David.

    Pieraccini, Massimiliano / Betti, Michele / Forcellini, Davide / Dei, Devis / Papi, Federico / Bartoli, Gianni / Facchini, Luca / Corazzi, Riccardo / Kovacevic, Vladimir Cerisano

    PloS one

    2017  Volume 12, Issue 4, Page(s) e0174480

    Abstract: This paper summarizes the results of a two-day dynamic monitoring of Michelangelo's David subject ... of the measuring instrument from the measurement of the David's displacement. Measurements were carried out in the presence ...

    Abstract This paper summarizes the results of a two-day dynamic monitoring of Michelangelo's David subject to environmental loads (city traffic and pedestrian loading induced by tourists visiting the Accademia Gallery). The monitoring was carried out by a no-contact technique using an interferometric radar, whose effectiveness in measuring the resonant frequencies of structures and historic monuments has proved over the last years through numerous monitoring activities. Owing to the dynamic behavior of the measurement system (radar and tripod), an accelerometer has been installed on the radar head to filter out the movement component of the measuring instrument from the measurement of the David's displacement. Measurements were carried out in the presence and absence of visitors, to assess their influence on the dynamic behavior of the statue. A numerical model of the statue was employed to evaluate the experimental results.
    MeSH term(s) Accelerometry ; Environment ; Humans ; Interferometry ; Models, Theoretical ; Museums ; Pedestrians ; Radar ; Sculpture ; Transportation ; Vibration
    Language English
    Publishing date 2017
    Publishing country United States
    Document type Journal Article
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0174480
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Radar detection of pedestrian-induced vibrations on Michelangelo's David.

    Massimiliano Pieraccini / Michele Betti / Davide Forcellini / Devis Dei / Federico Papi / Gianni Bartoli / Luca Facchini / Riccardo Corazzi / Vladimir Cerisano Kovacevic

    PLoS ONE, Vol 12, Iss 4, p e

    2017  Volume 0174480

    Abstract: This paper summarizes the results of a two-day dynamic monitoring of Michelangelo's David subject ... of the measuring instrument from the measurement of the David's displacement. Measurements were carried out in the presence ...

    Abstract This paper summarizes the results of a two-day dynamic monitoring of Michelangelo's David subject to environmental loads (city traffic and pedestrian loading induced by tourists visiting the Accademia Gallery). The monitoring was carried out by a no-contact technique using an interferometric radar, whose effectiveness in measuring the resonant frequencies of structures and historic monuments has proved over the last years through numerous monitoring activities. Owing to the dynamic behavior of the measurement system (radar and tripod), an accelerometer has been installed on the radar head to filter out the movement component of the measuring instrument from the measurement of the David's displacement. Measurements were carried out in the presence and absence of visitors, to assess their influence on the dynamic behavior of the statue. A numerical model of the statue was employed to evaluate the experimental results.
    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2017-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Editorial Commentary: Delivering the PROMIS for Patients With Shoulder Disorders-Fool's Gold, a Mirage, or an Oasis.

    Kovacevic, David

    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association

    2021  Volume 37, Issue 4, Page(s) 1310–1313

    Abstract: Comparative psychometric performance of Patient-Reported Outcome Measurement Information System (PROMIS) instruments to legacy patient-reported outcomes for shoulder disorders is relevant and timely, as numerous stakeholders are engaged in the process of ...

    Abstract Comparative psychometric performance of Patient-Reported Outcome Measurement Information System (PROMIS) instruments to legacy patient-reported outcomes for shoulder disorders is relevant and timely, as numerous stakeholders are engaged in the process of capturing, comparing, and evaluating performance results at the individual and population health levels. Depending on the stakeholder type, patient-reported outcomes could be used for clinical research, reimbursement, point-of-care, or benchmarking for patient comparison with a matched population cohort or comparative surgeon scorecard. Identifying and using the appropriate patient-reported outcome measure may be dependent on the purpose for measurement and stakeholder engagement and, as such, could be considered fool's gold, a mirage, or an oasis. At this time, PROMIS instruments are not a suitable replacement for legacy patient-reported outcomes when orthopaedic surgeons are looking to perform level I and level II clinical studies to develop future clinical practice guidelines grounded in strong evidence.
    MeSH term(s) Cohort Studies ; Humans ; Information Systems ; Patient Reported Outcome Measures ; Shoulder
    Language English
    Publishing date 2021-03-28
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 632528-2
    ISSN 1526-3231 ; 0749-8063
    ISSN (online) 1526-3231
    ISSN 0749-8063
    DOI 10.1016/j.arthro.2020.12.230
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Glycerol as a Substrate and Inactivator of Coenzyme B

    Bilić, Luka / Barić, Danijela / Sandala, Gregory M / Smith, David Mathew / Kovačević, Borislav

    Chemistry (Weinheim an der Bergstrasse, Germany)

    2021  Volume 27, Issue 29, Page(s) 7930–7941

    Abstract: Diol dehydratase, dependent on coenzyme ... ...

    Abstract Diol dehydratase, dependent on coenzyme B
    MeSH term(s) Cobamides ; Glycerol ; Humans ; Hydro-Lyases ; Phosphothreonine/analogs & derivatives ; Propanediol Dehydratase
    Chemical Substances Cobamides ; 7-mercaptoheptanoylthreonine phosphate (104302-77-4) ; Phosphothreonine (1114-81-4) ; Hydro-Lyases (EC 4.2.1.-) ; Propanediol Dehydratase (EC 4.2.1.28) ; Glycerol (PDC6A3C0OX)
    Language English
    Publishing date 2021-04-22
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1478547-X
    ISSN 1521-3765 ; 0947-6539
    ISSN (online) 1521-3765
    ISSN 0947-6539
    DOI 10.1002/chem.202100416
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The impact of collaborative organisational models and general practice size on patient safety and quality of care in the English National Health Service: A systematic review.

    Kovacevic, Lana / Naik, Ravi / Lugo-Palacios, David G / Ashrafian, Hutan / Mossialos, Elias / Darzi, Ara

    Health policy (Amsterdam, Netherlands)

    2023  Volume 138, Page(s) 104940

    Abstract: Collaborative primary care has become an increasingly popular strategy to manage existing pressures on general practice. In England, the recent changes taking place in the primary care sector have included the formation of collaborative organisational ... ...

    Abstract Collaborative primary care has become an increasingly popular strategy to manage existing pressures on general practice. In England, the recent changes taking place in the primary care sector have included the formation of collaborative organisational models and a steady increase in practice size. The aim of this review was to summarise the available evidence on the impact of collaborative models and general practice size on patient safety and quality of care in England. We searched for quantitative and qualitative studies on the topic published between January 2010 and July 2023. The quality of articles was assessed using the Newcastle-Ottawa Scale and the Critical Appraisal Skills Programme checklist. We screened 6533 abstracts, with full-text screening performed on 76 records. A total of 29 articles were included in the review. 19 met the inclusion criteria following full-text screening, with seven identified through reverse citation searching and three through expert consultation. All studies were found to be of moderate or high quality. A predominantly positive impact on service delivery measures and patient-level outcomes was identified. Meanwhile, the evidence on the effect on pay-for-performance outcomes and hospital admissions is mixed, with continuity of care and access identified as a concern. While this review is limited to evidence from England, the findings provide insights for all health systems undergoing a transition towards collaborative primary care.
    MeSH term(s) Humans ; Patient Safety ; State Medicine ; Models, Organizational ; Reimbursement, Incentive ; General Practice ; Quality of Health Care
    Language English
    Publishing date 2023-11-07
    Publishing country Ireland
    Document type Systematic Review ; Journal Article
    ZDB-ID 605805-x
    ISSN 1872-6054 ; 0168-8510
    ISSN (online) 1872-6054
    ISSN 0168-8510
    DOI 10.1016/j.healthpol.2023.104940
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Biological sex impacts perioperative complications after reverse shoulder arthroplasty for proximal humeral fracture.

    Ezuma, Chimere O / Kosber, Rashed L / Kovacevic, David

    JSES international

    2021  Volume 5, Issue 3, Page(s) 371–376

    Abstract: Background: The purpose of this study was to determine the difference in complication rates between males and females undergoing reverse shoulder arthroplasty for proximal humerus fractures. We hypothesized that (1) females were more likely to undergo ... ...

    Abstract Background: The purpose of this study was to determine the difference in complication rates between males and females undergoing reverse shoulder arthroplasty for proximal humerus fractures. We hypothesized that (1) females were more likely to undergo reverse shoulder arthroplasty for fracture, and (2) males were more likely to sustain a perioperative complication.
    Methods: The National Surgical Quality Improvement Program database was queried to identify patients who underwent reverse shoulder arthroplasty for proximal humerus fracture between 2011 and 2018. Patients were stratified based on biological sex. Patient demographics, comorbidities, and 30-day perioperative complication rates were collected. Univariate analyses and multiple variable logistic regression modeling were performed.
    Results: About 905 patients were included in the analysis-175 (19.3%) were male and 730 (80.7%) were female. Males were more likely to sustain perioperative complications (26.3% vs. 14.1%;
    Conclusion: Females were more likely to undergo reverse shoulder arthroplasty for proximal humerus fracture, but males were at increased risk of sustaining short-term complications. This study provides useful information for clinicians to consider when counseling their patients during the perioperative period.
    Language English
    Publishing date 2021-02-16
    Publishing country United States
    Document type Journal Article
    ISSN 2666-6383
    ISSN (online) 2666-6383
    DOI 10.1016/j.jseint.2020.12.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Fulminating deep tissue space infection with

    Glover, Joe / Kovacevic, Gorana / Walton, Gary / Parr, David

    BMJ case reports

    2020  Volume 13, Issue 3

    Abstract: Management of sore throat requires robust decision-making to balance successfully the conflicting risks of unnecessary antibiotic use against those of untreated bacterial infection. We present a case of fulminant sepsis caused ... ...

    Abstract Management of sore throat requires robust decision-making to balance successfully the conflicting risks of unnecessary antibiotic use against those of untreated bacterial infection. We present a case of fulminant sepsis caused by
    MeSH term(s) Abscess/diagnostic imaging ; Abscess/microbiology ; Adult ; Humans ; Male ; Neck/diagnostic imaging ; Neck/microbiology ; Pharyngitis/microbiology ; Pharyngitis/therapy ; Sepsis/etiology ; Sepsis/microbiology ; Streptococcal Infections/complications ; Streptococcal Infections/microbiology ; Streptococcal Infections/therapy ; Streptococcus constellatus/isolation & purification
    Language English
    Publishing date 2020-03-31
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2019-233971
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Tracer test analysis using flow and transport simulation code and new analytical transport model 27 April 2019.

    Mitrinović, David / Kovačević, Srđan / Vojt, Predrag / Pušić, Milenko / Dimkić, Milan

    Water environment research : a research publication of the Water Environment Federation

    2019  Volume 91, Issue 9, Page(s) 940–953

    Abstract: A convergent flow field tracer test, in two phases, with injection of sodium chloride solution, was conducted on a pumping well and neighboring piezometers belonging to the Kovin-Dubovac area drainage system, on the Serbian sector of the Danube River. ... ...

    Abstract A convergent flow field tracer test, in two phases, with injection of sodium chloride solution, was conducted on a pumping well and neighboring piezometers belonging to the Kovin-Dubovac area drainage system, on the Serbian sector of the Danube River. The initial goal was to determine the values of hydrogeological parameters in order to analyze the results of the subsequent experiments involving injection of the selected solutes. SEAWAT code (through the Visual Modflow™ 2011 interface), as well as the newly developed analytical model for multilayer setting (1D transport solution for tracer injected as a Dirac impulse in a radial convergent flow field), was used to develop and calibrate a model of the studied portion of the aquifer. The new analytical model demonstrated a very good match to the measured values and to the results of numerical simulation, which indicates that it can be of great utility in characterizing transport conditions. PRACTITIONER POINTS: Results confirm the conclusions of research papers on tracer tests that 10-m scale tests regularly point to heterogeneous aquifer. New analytical 1D radial transport model for multilayer setting demonstrated a very good match with numerical simulation and experimental data. Developed analytical model is usable for characterizing transport conditions in a radial convergent multilayer flow field or other settings.
    MeSH term(s) Groundwater ; Models, Theoretical ; Water Movements
    Language English
    Publishing date 2019-05-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1098976-6
    ISSN 1554-7531 ; 1047-7624 ; 1061-4303
    ISSN (online) 1554-7531
    ISSN 1047-7624 ; 1061-4303
    DOI 10.1002/wer.1135
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Metabolome Profiling in the Plasma of Dogs with Idiopathic Dilated Cardiomyopathy: A Multiplatform Mass-Spectrometry-Based Approach.

    Rubić, Ivana / Weidt, Stefan / Burchmore, Richard / Kovačević, Alan / Kuleš, Josipa / Eckersall, Peter David / Torti, Marin / Jović, Ines / Kovačić, Mislav / Gotić, Jelena / Barić Rafaj, Renata / Novak, Predrag / Samardžija, Marko / Mrljak, Vladimir

    International journal of molecular sciences

    2023  Volume 24, Issue 20

    Abstract: Dilated cardiomyopathy is one of the important diseases in dogs and humans. The second most common cause of heart failure in dogs is idiopathic dilated cardiomyopathy (iDCM), which results in heart failure or sudden cardiac death due to arrhythmia. This ... ...

    Abstract Dilated cardiomyopathy is one of the important diseases in dogs and humans. The second most common cause of heart failure in dogs is idiopathic dilated cardiomyopathy (iDCM), which results in heart failure or sudden cardiac death due to arrhythmia. This study aimed to determine changes in the plasma metabolome of dogs with iDCM compared to healthy dogs. For that purpose, a multiplatform mass-spectrometry-based approach was used. In this study, we included two groups of dogs: 12 dogs with iDCM and 8 healthy dogs. A total of 272 metabolites were detected in the plasma samples of dogs by combining three approaches but four MS-based platforms (GC-MS, LC-MS (untargeted), LC-MS (targeted), and FIA-MS (targeted) methods). Our findings demonstrated changes in the canine plasma metabolome involved in the development of iDCM, including the different concentrations of amino acids, biogenic amines, acylcarnitines, triglycerides and diglycerides, sphingomyelins, and organic acids. The results of this study will enable the detection and monitoring of pathophysiological mechanisms involved in the development of iDCM in the future.
    MeSH term(s) Humans ; Dogs ; Animals ; Cardiomyopathy, Dilated/metabolism ; Heart Failure ; Metabolome ; Amino Acids/metabolism ; Gas Chromatography-Mass Spectrometry
    Chemical Substances Amino Acids
    Language English
    Publishing date 2023-10-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms242015182
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Augmentation of Rotator Cuff Healing With Orthobiologics.

    Kovacevic, David / Suriani, Robert J / Levine, William N / Thomopoulos, Stavros

    The Journal of the American Academy of Orthopaedic Surgeons

    2021  Volume 30, Issue 5, Page(s) e508–e516

    Abstract: The limited regenerative capacity of the tendon-bone enthesis after surgical repair poses a significant challenge to achieving desired clinical outcomes. Biologic augmentation of the repair site has the potential to enhance the biomechanical and ... ...

    Abstract The limited regenerative capacity of the tendon-bone enthesis after surgical repair poses a significant challenge to achieving desired clinical outcomes. Biologic augmentation of the repair site has the potential to enhance the biomechanical and histological integrity of the enthesis, leading to lower retear rates and greater patient satisfaction. Platelet-rich plasma, stem cells and bone marrow aspirate concentrate, growth factors, biodegradable or biomimetic scaffolds, and amniotic products have been investigated in preclinical and, in some cases, clinical studies aimed at augmenting tendon-bone healing. Although many of these therapies have achieved some degree of success in improving structural, histological, and clinical outcomes after surgical tendon-bone enthesis repair, none have reliably and consistently lead to clinical improvement. High-quality randomized controlled clinical studies are needed to definitively evaluate the efficacy of these biologic therapies and ultimately determine which, if any, are capable of achieving a tendon-bone repair that is structurally noninferior to the native enthesis before injury.
    MeSH term(s) Humans ; Platelet-Rich Plasma ; Rotator Cuff/surgery ; Rotator Cuff Injuries/pathology ; Rotator Cuff Injuries/surgery ; Tendons/surgery ; Wound Healing
    Language English
    Publishing date 2021-12-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1200524-1
    ISSN 1940-5480 ; 1067-151X
    ISSN (online) 1940-5480
    ISSN 1067-151X
    DOI 10.5435/JAAOS-D-20-01011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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