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  1. Book: The sperm cell

    De Jonge, Christopher J. / Barratt, Christopher

    production, maturation, fertilization, regeneration

    (Cambridge medicine)

    2017  

    Author's details edited by Christopher J. De Jonge, Christopher L. R. Barratt
    Series title Cambridge medicine
    Keywords Spermatozoa
    Language English
    Size xiii, 304 Seiten, Illustrationen, Diagramme, 26 cm
    Edition Second edition
    Publisher Cambridge University Press
    Publishing place Cambridge
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT019724381
    ISBN 978-1-107-12632-9 ; 9781108139144 ; 1-107-12632-0 ; 1108139140
    Database Catalogue ZB MED Medicine, Health

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  2. Book ; Online: Chapter 12 Landscape Appreciation in the English Lake District

    De Jonge, Krista / Cattoor, Bieke / Coomans, Thomas / Taylor, Joanna E. / Gregory, Ian / Donaldson, Christopher

    2019  

    Abstract: The relational complexity of urban and rural landscapes in space and in time.The development of historical geographical information systems (HGIS) and other methods from the digital humanities have revolutionised historical research on cultural ... ...

    Abstract The relational complexity of urban and rural landscapes in space and in time.The development of historical geographical information systems (HGIS) and other methods from the digital humanities have revolutionised historical research on cultural landscapes. Additionally, the opening up of increasingly diverse collections of source material, often incomplete and difficult to interpret, has led to methodologically innovative experiments. One of today's major challenges, however, concerns the concepts and tools to be deployed for mapping processes of transformation-that is, interpreting and imagining the relational complexity of urban and rural landscapes, both in space and in time, at micro- and macro-scale.Mapping Landscapes in Transformation gathers experts from different disciplines, active in the fields of historical geography, urban and landscape history, archaeology and heritage conservation. They are specialised in a wide variety of space-time contexts, including regions within Europe, Asia, and the Americas, and periods from antiquity to the 21st century
    Keywords Archaeology ; History (General) ; Architecture
    Size 1 electronic resource ( p.)
    Publisher Leuven University Press
    Publishing place Verlagsort nicht ermittelbar
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020196075
    ISBN 9789461662835 ; 9789462701731 ; 9461662831 ; 9462701733
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book: The sperm cell

    De Jonge, Christopher J.

    production, maturation, fertilization, regeneration

    2006  

    Author's details ed. by Christopher De Jonge
    Keywords Spermatozoa
    Subject code 612.61
    Language English
    Size XI, 359 S., [6] Bl. : Ill.
    Publisher Cambridge Univ. Press
    Publishing place Cambridge u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT014664006
    ISBN 978-0-521-85397-2 ; 0-521-85397-4
    Database Catalogue ZB MED Medicine, Health

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  4. Article: Counting the Hidden Costs of Male Reproductive Health.

    De Jonge, Christopher J / Barratt, Christopher L R / Pacey, Allan A

    The world journal of men's health

    2022  Volume 40, Issue 2, Page(s) 344–345

    Language English
    Publishing date 2022-01-01
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2719786-4
    ISSN 2287-4690 ; 2287-4208
    ISSN (online) 2287-4690
    ISSN 2287-4208
    DOI 10.5534/wjmh.210181
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Don't forget the father.

    Eisenberg, Michael L / Barratt, Christopher L R / De Jonge, Christopher J

    Fertility and sterility

    2022  Volume 117, Issue 5, Page(s) 936–937

    MeSH term(s) Fathers ; Humans ; Male
    Language English
    Publishing date 2022-05-05
    Publishing country United States
    Document type Editorial
    ZDB-ID 80133-1
    ISSN 1556-5653 ; 0015-0282
    ISSN (online) 1556-5653
    ISSN 0015-0282
    DOI 10.1016/j.fertnstert.2022.03.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: Assisted reproductive technology

    De Jonge, Christopher J.

    accomplishments and new horizons

    2002  

    Author's details ed. by Christopher J. De Jonge
    Keywords Reproduction Techniques ; Embryo Transfer ; Fertilization in Vitro ; Infertility / diagnosis ; Infertility / therapy
    Language English
    Size XIV, 431 S. : Ill., graph. Darst.
    Publisher Cambridge Univ. Press
    Publishing place Cambridge
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT013417835
    ISBN 0-521-80121-4 ; 978-0-521-80121-8
    Database Catalogue ZB MED Medicine, Health

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  7. Article ; Online: Research funding for male reproductive health and infertility in the UK and USA [2016 - 2019].

    Gumerova, Eva / De Jonge, Christopher J / Barratt, Christopher L R

    Human fertility (Cambridge, England)

    2022  Volume 26, Issue 3, Page(s) 439–449

    Abstract: There is a paucity of data on research funding levels for male reproductive health (MRH). We investigated the research funding for MRH and infertility by examining publicly accessible web-databases from the UK and USA government funding agencies. ... ...

    Abstract There is a paucity of data on research funding levels for male reproductive health (MRH). We investigated the research funding for MRH and infertility by examining publicly accessible web-databases from the UK and USA government funding agencies. Information on the funding was collected from the UKRI-GTR, the NIHR's Open Data Summary, and the USA's NIH RePORT web-databases. Funded projects between January 2016 and December 2019 were recorded and funding support was divided into three research categories: (i) male-based; (ii) female-based; and (iii) not-specified. Between January 2016 and December 2019, UK agencies awarded a total of £11,767,190 to 18 projects for male-based research and £29,850,945 to 40 projects for female-based research. There was no statistically significant difference in the median funding grant awarded within the male-based and female-based categories (
    MeSH term(s) Humans ; Male ; Female ; Reproductive Health ; Infertility, Male ; Biomedical Research ; Reproduction ; United Kingdom
    Language English
    Publishing date 2022-03-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2086960-5
    ISSN 1742-8149 ; 1464-7273
    ISSN (online) 1742-8149
    ISSN 1464-7273
    DOI 10.1080/14647273.2022.2045521
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Counting the Hidden Costs of Male Reproductive Health

    Christopher J. De Jonge / Christopher L.R. Barratt / Allan A. Pacey

    The World Journal of Men's Health, Vol 40, Iss 2, Pp 344-

    2022  Volume 345

    Keywords Medicine ; R ; Diseases of the genitourinary system. Urology ; RC870-923
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher Korean Society for Sexual Medicine and Andrology
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: A clinical assay for reactive oxygen species - ready for primetime?

    De Jonge, Christopher J

    Reproductive biomedicine online

    2017  

    Abstract: Reactive oxygen species (ROS) have been demonstrated to have damaging effects on human sperm function. The measurement of ROS as an adjunct to traditional semen analysis has clinical relevance as part of the diagnosis of male infertility. The assay best ... ...

    Abstract Reactive oxygen species (ROS) have been demonstrated to have damaging effects on human sperm function. The measurement of ROS as an adjunct to traditional semen analysis has clinical relevance as part of the diagnosis of male infertility. The assay best suited to the clinical laboratory environment for detecting ROS generation remains somewhat controversial. A recent report on a multicenter study evaluating the reduction of nitroblue tetrazolium (NBT) to formazan precipitate as an indirect reporter of ROS-generating activity in spermatozoa, seminal plasma and semen has received a critique raising questions as to the sensitivity and specificity of the assay for detecting ROS. The authors of the report argue in response that the assay has validity and yields results that are potentially clinically significant. This dialogue serves to (re)direct readers to the original article and to consider carefully the intent and potential application of the assay, and whether there is sufficient scientific evidence to judiciously support its clinical diagnostic application.
    Language English
    Publishing date 2017-10-04
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2113823-0
    ISSN 1472-6491 ; 1472-6483
    ISSN (online) 1472-6491
    ISSN 1472-6483
    DOI 10.1016/j.rbmo.2017.09.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Biological basis for human capacitation-revisited.

    De Jonge, Christopher

    Human reproduction update

    2017  Volume 23, Issue 3, Page(s) 289–299

    Abstract: Background: A little more than a decade ago a review entitled 'Biological basis for human capacitation' was published. A primary conclusion of the review was that with all the technological advances that have been made since the first experiments ... ...

    Abstract Background: A little more than a decade ago a review entitled 'Biological basis for human capacitation' was published. A primary conclusion of the review was that with all the technological advances that have been made since the first experiments demonstrated the in vivo requirement of capacitation for fertilization, very little progress had since been made, most significantly for human.
    Objective and rationale: The present review was carried out to provide an update on the biological basis for human capacitation. It briefly revisits the original schema, presents a review of the literature that urged research interest in human sperm capacitation and puts under the spotlight the original definition of capacitation balanced against the limitations of experiments in vitro to characterize a complex process that necessarily mandates a female component, and very recent findings in the mouse. It also includes proposed considerations for new thinking regarding capacitation, and progress toward understanding the biology of human capacitation.
    Search methods: The PubMed, Google Scholar and Scopus literature databases were reviewed extensively using inclusive, broad and multispecies search terms without publication date limitation.
    Outcomes: Comprehensive screening of the literature database showed that no papers regarding human sperm capacitation in vivo have been published in the past 20 years. Recent experiments in the mouse have provided compelling and unanticipated data regarding capacitation and in vivo fertilization. Questions were posed and addressed regarding: stimuli for initiation of capacitation, capacitation relative to the cumulus-oocyte complex, comparison between in vivo and in vitro capacitation, and potential species-specific differences in location and timing of capacitation.
    Wider implications: There has been no progress on the in vivo biology of human sperm capacitation since before the turn of the century. Human IVF and its technologies may likely have inhibited, and continue to hold back, any future in vivo experiments that would address one or more questions regarding acquisition of fertilizing capacity in human. The limiting factor for progress in the area is access to funding and human subjects.
    MeSH term(s) Animals ; Biomedical Research ; Female ; Humans ; Male ; Mice ; Publishing/statistics & numerical data ; Rabbits ; Sperm Capacitation/physiology ; Sperm Transport/physiology ; Spermatozoa/physiology
    Language English
    Publishing date 2017-01-20
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1286738-x
    ISSN 1460-2369 ; 1355-4786
    ISSN (online) 1460-2369
    ISSN 1355-4786
    DOI 10.1093/humupd/dmw048
    Database MEDical Literature Analysis and Retrieval System OnLINE

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