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  1. Book: Special issue: a celebration of Harry B. Gray's 75th birthday

    Gray, Harry B / Winkler, Jay R

    (Coordination chemistry reviews ; 255.2011,7/8)

    2011  

    Author's details guest ed.: Jay R. Winkler
    Series title Coordination chemistry reviews ; 255.2011,7/8
    Language English
    Size S. 617 - 989, graph. Darst.
    Publisher Elsevier
    Publishing place Amsterdam u.a.
    Document type Book
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  2. Article: Mentoring: Reflections and Suggestions.

    Gray, Harry B

    ACS central science

    2019  Volume 5, Issue 9, Page(s) 1475–1476

    Language English
    Publishing date 2019-09-27
    Publishing country United States
    Document type Editorial
    ISSN 2374-7943
    ISSN 2374-7943
    DOI 10.1021/acscentsci.9b00840
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Functional and protective hole hopping in metalloenzymes.

    Gray, Harry B / Winkler, Jay R

    Chemical science

    2021  Volume 12, Issue 42, Page(s) 13988–14003

    Abstract: Electrons can tunnel through proteins in microseconds with a modest release of free energy over distances in the 15 to 20 Å range. To span greater distances, or to move faster, multiple charge transfers (hops) are required. When one of the reactants is a ...

    Abstract Electrons can tunnel through proteins in microseconds with a modest release of free energy over distances in the 15 to 20 Å range. To span greater distances, or to move faster, multiple charge transfers (hops) are required. When one of the reactants is a strong oxidant, it is convenient to consider the movement of a positively charged "hole" in a direction opposite to that of the electron. Hole hopping along chains of tryptophan (Trp) and tyrosine (Tyr) residues is a critical function in several metalloenzymes that generate high-potential intermediates by reactions with O
    Language English
    Publishing date 2021-09-27
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2559110-1
    ISSN 2041-6539 ; 2041-6520
    ISSN (online) 2041-6539
    ISSN 2041-6520
    DOI 10.1039/d1sc04286f
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Resonance Raman spectra of blue copper proteins: Variable temperature spectra of Thermus thermophilus HB27 laccase.

    Kang, Janice / Shin, Jieun / Gray, Harry B / Winkler, Jay R

    Journal of inorganic biochemistry

    2023  Volume 248, Page(s) 112362

    Abstract: The resonance Raman (rR) spectra of the oxidized type 1 copper active site ( ... ...

    Abstract The resonance Raman (rR) spectra of the oxidized type 1 copper active site (Cu
    MeSH term(s) Female ; Humans ; Laccase ; Copper ; Thermus thermophilus ; Temperature ; Vibration
    Chemical Substances Laccase (EC 1.10.3.2) ; Copper (789U1901C5)
    Language English
    Publishing date 2023-08-24
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 162843-4
    ISSN 1873-3344 ; 0162-0134
    ISSN (online) 1873-3344
    ISSN 0162-0134
    DOI 10.1016/j.jinorgbio.2023.112362
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Mentoring

    Harry B. Gray

    ACS Central Science, Vol 5, Iss 9, Pp 1475-

    Reflections and Suggestions

    2019  Volume 1476

    Keywords Chemistry ; QD1-999
    Language English
    Publishing date 2019-09-01T00:00:00Z
    Publisher American Chemical Society
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Tryptophan extends the life of cytochrome P450.

    Ravanfar, Raheleh / Sheng, Yuling / Gray, Harry B / Winkler, Jay R

    Proceedings of the National Academy of Sciences of the United States of America

    2023  Volume 120, Issue 50, Page(s) e2317372120

    Abstract: Powerfully oxidizing enzymes need protective mechanisms to prevent self-destruction. The flavocytochrome P450 BM3 ... ...

    Abstract Powerfully oxidizing enzymes need protective mechanisms to prevent self-destruction. The flavocytochrome P450 BM3 from
    MeSH term(s) Oxidation-Reduction ; Tryptophan/metabolism ; NADP/metabolism ; NADPH-Ferrihemoprotein Reductase/genetics ; NADPH-Ferrihemoprotein Reductase/chemistry ; NADPH-Ferrihemoprotein Reductase/metabolism ; Cytochrome P-450 Enzyme System/metabolism ; Fatty Acids/metabolism ; Heme/metabolism ; Tyrosine/metabolism ; Bacterial Proteins/metabolism
    Chemical Substances Tryptophan (8DUH1N11BX) ; NADP (53-59-8) ; NADPH-Ferrihemoprotein Reductase (EC 1.6.2.4) ; Cytochrome P-450 Enzyme System (9035-51-2) ; Fatty Acids ; Heme (42VZT0U6YR) ; Tyrosine (42HK56048U) ; Bacterial Proteins
    Language English
    Publishing date 2023-12-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.2317372120
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Conjecture on the Design of Helical Proteins.

    Kozak, John J / Gray, Harry B

    The journal of physical chemistry. B

    2020  Volume 124, Issue 49, Page(s) 11067–11071

    Abstract: In an important advance in our understanding of protein folding, Wolynes and Onuchic found that the frustration ratio, ...

    Abstract In an important advance in our understanding of protein folding, Wolynes and Onuchic found that the frustration ratio,
    MeSH term(s) Peptides ; Protein Conformation ; Protein Folding ; Proteins ; Thermodynamics
    Chemical Substances Peptides ; Proteins
    Language English
    Publishing date 2020-11-24
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ISSN 1520-5207
    ISSN (online) 1520-5207
    DOI 10.1021/acs.jpcb.0c05669
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Nanomedicine: controlling nanoparticle clearance for translational success.

    Zhu, Geyunjian Harry / Gray, Alex B C / Patra, Hirak K

    Trends in pharmacological sciences

    2022  Volume 43, Issue 9, Page(s) 709–711

    Abstract: Achieving complete nanoparticle (NP) clearance is a key consideration in the design of safe and translatable nanomedicines. Renal-clearable nano formulations must encompass the beneficial nanoscale functionalities whilst exhibiting clearance profiles ... ...

    Abstract Achieving complete nanoparticle (NP) clearance is a key consideration in the design of safe and translatable nanomedicines. Renal-clearable nano formulations must encompass the beneficial nanoscale functionalities whilst exhibiting clearance profiles like those of small-molecule therapeutics. Recent developments in the field have enabled the growth of novel renal-clearable NPs with transformable sizes that take advantage of alternative clearance mechanisms to achieve controlled and efficient renal excretion to improve potential clinical translation.
    MeSH term(s) Drug Compounding ; Humans ; Nanomedicine ; Nanoparticles
    Language English
    Publishing date 2022-05-31
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 282846-7
    ISSN 1873-3735 ; 0165-6147
    ISSN (online) 1873-3735
    ISSN 0165-6147
    DOI 10.1016/j.tips.2022.05.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Tryptophan to Tryptophan Hole Hopping in an Azurin Construct.

    Melčák, Martin / Šebesta, Filip / Heyda, Jan / Gray, Harry B / Záliš, Stanislav / Vlček, Antonín

    The journal of physical chemistry. B

    2023  Volume 128, Issue 1, Page(s) 96–108

    Abstract: Electron transfer (ET) between neutral and cationic tryptophan residues in the azurin construct [ ... ...

    Abstract Electron transfer (ET) between neutral and cationic tryptophan residues in the azurin construct [Re
    MeSH term(s) Azurin/chemistry ; Tryptophan/chemistry ; Oxidation-Reduction ; Electron Transport ; Indoles
    Chemical Substances Azurin (12284-43-4) ; Tryptophan (8DUH1N11BX) ; Indoles
    Language English
    Publishing date 2023-12-25
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5207
    ISSN (online) 1520-5207
    DOI 10.1021/acs.jpcb.3c06568
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Photoredox Catalysis Mediated by Tungsten(0) Arylisocyanides in 1,2-Difluorobenzene.

    Barth, Alexandra T / Morales, Maryann / Winkler, Jay R / Gray, Harry B

    Inorganic chemistry

    2022  Volume 61, Issue 19, Page(s) 7251–7255

    Abstract: We have studied the photochemical cyclization of 1-(2-iodobenzyl)-pyrrole (IBP) and 1-(2-bromobenzyl)-pyrrole (BBP) to ... ...

    Abstract We have studied the photochemical cyclization of 1-(2-iodobenzyl)-pyrrole (IBP) and 1-(2-bromobenzyl)-pyrrole (BBP) to 5
    MeSH term(s) Catalysis ; Cyclization ; Fluorobenzenes ; Pyrroles ; Tungsten
    Chemical Substances Fluorobenzenes ; Pyrroles ; 1,2-difluorobenzene (367-11-3) ; Tungsten (V9306CXO6G)
    Language English
    Publishing date 2022-04-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1484438-2
    ISSN 1520-510X ; 0020-1669
    ISSN (online) 1520-510X
    ISSN 0020-1669
    DOI 10.1021/acs.inorgchem.1c03767
    Database MEDical Literature Analysis and Retrieval System OnLINE

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