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Article ; Online: Propagation of aberrated wavefronts using a ray transfer matrix.

Raasch, Thomas W

Journal of the Optical Society of America. A, Optics, image science, and vision

2014 Volume 31, Issue 5, Page(s) 964–967

Abstract: A ray transfer matrix is used to calculate the propagation of aberrated wavefronts across a homogeneous refractive index. The wavefront is represented by local surface normals, i.e., by a ray bundle, and the propagation is accomplished by transferring ... ...

Abstract	A ray transfer matrix is used to calculate the propagation of aberrated wavefronts across a homogeneous refractive index. The wavefront is represented by local surface normals, i.e., by a ray bundle, and the propagation is accomplished by transferring those rays across the space. Wavefront shape is generated from the slopes and positions of the collection of rays. Calculation methods are developed for the paraxial case, for higher-order expansions, and for the exact tangent case. A numerical example is used to compare results between an analytical method and the methods developed here.
MeSH term(s)	Algorithms ; Computer Simulation ; Light ; Models, Theoretical ; Refractometry/methods ; Scattering, Radiation
Language	English
Publishing date	2014-05-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	283633-6
ISSN	1520-8532 ; 1084-7529 ; 0740-3232
ISSN (online)	1520-8532
ISSN	1084-7529 ; 0740-3232
DOI	10.1364/JOSAA.31.000964
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Book ; Thesis: Ciprofloxacin

Raasch, Walter

Untersuchungen zu Metabolismus und Gewebepenetration beim Menschen sowie Einfluss auf den zentralen Stoffwechsel biogener Amine bei der Ratte

1990

Author's details	vorgelegt von Walter Raasch
Size	[3], 131 S. : Ill., graph. Darst.
Document type	Book ; Thesis
Thesis / German Habilitation thesis	Regensburg, Univ., Diss., 1990
HBZ-ID	HT003819508
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Article ; Online: Relationships Among Shoulder Rotational Strength, Range of Motion, Pitching Kinetics, and Pitch Velocity in Collegiate Baseball Pitchers.

Cross, Janelle A / Higgins, Austin W / Dziuk, Cody C / Harris, Gerald F / Raasch, William G

Journal of strength and conditioning research

2022

Abstract: Abstract: Cross, JA, Higgins, AW, Dziuk, CC, Harris, GF, and Raasch, WG. Relationships ...

Abstract	Abstract: Cross, JA, Higgins, AW, Dziuk, CC, Harris, GF, and Raasch, WG. Relationships among shoulder rotational strength, range of motion, pitching kinetics, and pitch velocity in collegiate baseball pitchers. J Strength Cond Res XX(X): 000-000, 2022-Throwing shoulder injuries are the most common type of injury experienced by baseball pitchers. Weakness in the shoulder musculature and insufficient throwing arm range of motion are both risk factors for developing a shoulder injury. The goal of this study was to determine correlations among shoulder rotational strength, range of motion, pitching kinetics, and pitch velocity in collegiate pitchers. Thirteen uninjured male college pitchers were evaluated. Clinical measures included shoulder internal and external rotation range of motion, peak isokinetic internal and external rotator strength, and peak isometric internal and external rotator strength. Three-dimensional biomechanics were assessed as subjects threw from an indoor pitching mound to a strike zone net at regulation distance. Pearson's correlations were used to assess the associations among the clinical measures and throwing metrics. Five significant correlations were found between peak shoulder compressive force and strength, and 4 significant correlations were found between pitching velocity and strength (p < 0.05). No significant correlations were found between range of motion and pitching kinetics or velocity. Our results suggest that as shoulder rotational strength increases, the peak shoulder compressive force and pitch velocity both increase. Knowledge of relationships between strength metrics and pitching biomechanics may allow for improved strength training routines with the goal of increasing velocity without increasing injury risk.
Language	English
Publishing date	2022-03-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	1156349-7
ISSN	1533-4287 ; 1064-8011
ISSN (online)	1533-4287
ISSN	1064-8011
DOI	10.1519/JSC.0000000000004246
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Article: Correlation of Joint Space Widening on Valgus Stress Magnetic Resonance Imaging With Level of Play and Innings Pitched in Professional Pitchers.

Patel, Midhat / Schenk, Mari / Rangan, Pooja / Crenshaw, Ken / Caplinger, Roger / Raasch, William / Waslewski, Gary / Lederman, Evan / Lund, Pamela

Orthopaedic journal of sports medicine

2023 Volume 11, Issue 11, Page(s) 23259671231209704

Abstract: Background: Previous studies have described various techniques and confirmed the clinical utility of valgus stress radiography and stress ultrasound in overhead athletes. The addition of valgus stress and a high-resolution anatomic assessment of the ... ...

Abstract	Background: Previous studies have described various techniques and confirmed the clinical utility of valgus stress radiography and stress ultrasound in overhead athletes. The addition of valgus stress and a high-resolution anatomic assessment of the elbow with magnetic resonance imaging (MRI) in the active throwing position (flexed elbow valgus external rotation [FEVER] view) can add valuable diagnostic or prognostic information in throwing athletes. Purpose/hypothesis: The purpose of this study was to evaluate findings on MRI and subsequent performance in professional throwing athletes. It was hypothesized that joint space widening in the FEVER view would be predictive of performance and the risk of subsequent injuries. Study design: Cross-sectional study; Level of evidence, 3. Methods: All pitchers on 2 Major League Baseball teams who consented to participate during their preseason screening in 2019 and 2020 underwent standard and FEVER MRI, and performance data from the following season were recorded, including injuries, mean throwing velocity, number of innings pitched, strikeout percentage, walk percentage, weighted on-base average, and level of play reached (not signed, minor league, or major league). Categorical variables were compared using the Fisher exact test or chi-square test, and continuous variables were compared using the Kruskal-Wallis test, as appropriate. Ordered logistic regression was used to determine the independent factors predicting performance. Results: A total of 91 players underwent preseason imaging, and all players had subsequent performance data available. Multivariate analysis revealed that when controlling for age, mean velocity, history of injuries, presence of symptoms, and history of ulnar collateral ligament reconstruction, increased absolute joint space widening was predictive of a lower level of play (β = -0.63; Conclusion: The present study demonstrates that findings on MRI with valgus stress correlated with the level of play reached and number of innings pitched in professional throwing athletes.
Language	English
Publishing date	2023-11-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	2706251-X
ISSN	2325-9671
ISSN	2325-9671
DOI	10.1177/23259671231209704
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Article ; Online: Learning Post-Stroke Gait Training Strategies by Modeling Patient-Therapist Interaction.

Sorkhabadi, Seyed Mostafa Rezayat / Smith, Mason / Khodmbashi, Roozbeh / Lopez, Rachel / Raasch, Melissa / Maruyama, Trent / Kwasnica, Christina / Zhang, Wenlong

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society

2023 Volume PP

Abstract: For safe and effective robot-aided gait training, it is essential to incorporate the knowledge and expertise of physical therapists. Toward this goal, we directly learn from physical therapists' demonstrations of manual gait assistance in stroke ... ...

Abstract	For safe and effective robot-aided gait training, it is essential to incorporate the knowledge and expertise of physical therapists. Toward this goal, we directly learn from physical therapists' demonstrations of manual gait assistance in stroke rehabilitation. Lower-limb kinematics of patients and assistive force applied by therapists to the patient's leg are measured using a wearable sensing system which includes a custom-made force sensing array. The collected data is then used to characterize a therapist's strategies in response to unique gait behaviors found within a patient's gait. Preliminary analysis shows that knee extension and weight-shifting are the most important features that shape a therapist's assistance strategies. These key features are then integrated into a virtual impedance model to predict the therapist's assistive torque. This model benefits from a goal-directed attractor and representative features that allow intuitive characterization and estimation of a therapist's assistance strategies. The resulting model is able to accurately capture high-level therapist behaviors over the course of a full training session (r
Language	English
Publishing date	2023-03-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	1166307-8
ISSN	1558-0210 ; 1063-6528 ; 1534-4320
ISSN (online)	1558-0210
ISSN	1063-6528 ; 1534-4320
DOI	10.1109/TNSRE.2023.3253795
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Article ; Online: Vision, Driving Exposure, and Collisions in Bioptic Drivers.

Zhou, Alicia M / Flom, Roanne E / Raasch, Thomas W / Segerstrom, Ellen E / Dougherty, Bradley E

Optometry and vision science : official publication of the American Academy of Optometry

2021 Volume 99, Issue 2, Page(s) 121–126

Abstract: Significance: Lack of knowledge regarding the mileage driven by drivers with low vision who use bioptic telescopes could obscure the relationship between vision and road safety. This study provides data suggesting that worse vision is correlated with ... ...

Abstract	Significance: Lack of knowledge regarding the mileage driven by drivers with low vision who use bioptic telescopes could obscure the relationship between vision and road safety. This study provides data suggesting that worse vision is correlated with less mileage driven but more collisions per mile in bioptic drivers. Purpose: The purpose of this study was to determine whether vision or demographic factors predict mileage driven in bioptic drivers and per-mile motor vehicle collision rate and also to compare the collision rate of bioptic drivers with previous estimates for the general population. Methods: Driver data were collected retrospectively from clinic records. Collision data were collected from the Ohio Bureau of Motor Vehicles database. Subjects were also asked to estimate their yearly mileage. Regression models were used to investigate relationships between vision and collision rates. Results: Seventy-three licensed Ohio bioptic drivers (36 male) were included. Mean ± standard deviation age was 51 ± 16 years. Mean logMAR visual acuity was 0.67 (approximately 20/100). Mean log contrast sensitivity was 1.57. Mean reported annual mileage was 9746. Age, sex, and previous (nonbioptic) driving experience were not associated with mileage. LogMAR visual acuity was inversely related to mileage (P = .02), and contrast sensitivity (P = .01) and horizontal visual field (P = .02) were directly associated with mileage. Visual acuity (P = .02) and visual field (P = .005), but not contrast sensitivity (P = .19), were associated with number of collisions. Conclusions: Visual acuity, visual field, and contrast sensitivity were associated with driving exposure in bioptic drivers (with drivers with poorer vision reporting lower annual mileage), and poorer visual acuity and visual field were associated with more collisions. The per-mile collision rate for bioptic drivers was within the range of that previously reported for fully sighted drivers, although higher than would be expected for fully sighted drivers of similar age distribution.
MeSH term(s)	Accidents, Traffic ; Adult ; Aged ; Automobile Driving ; Eyeglasses ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Telescopes ; Vision, Low/epidemiology
Language	English
Publishing date	2021-12-07
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	1001706-9
ISSN	1538-9235 ; 1040-5488
ISSN (online)	1538-9235
ISSN	1040-5488
DOI	10.1097/OPX.0000000000001836
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Article ; Online: Influence of AT1 blockers on obesity and stress induced eating of cafeteria diet.

Gustaityte, Viktorija / Winkler, Martina / Stoelting, Ines / Raasch, Walter

The Journal of endocrinology

2018

Abstract: Based on findings that treatment with AT1 receptor blocker (ARB) prevents diet-induced obesity and that the activity of the hypothalamic-pituitary-adrenal (HPA) axis is stimulated by AngII and blocked by ARBs, we aimed to investigate whether ARB ... ...

Abstract	Based on findings that treatment with AT1 receptor blocker (ARB) prevents diet-induced obesity and that the activity of the hypothalamic-pituitary-adrenal (HPA) axis is stimulated by AngII and blocked by ARBs, we aimed to investigate whether ARB treatment can reduce stress-induced eating of cafeteria diet (CD) , thus contributing to alterations in eating behavior. Sprague Dawley rats were fed with chow or CD and treated with telmisartan (TEL, 8mg/kg/d) or vehicle. At weeks 2 and 12, rats were stressed over 5 consecutive days by restraint stress (RS, 4h) and by additional shaking at d5. Tail blood was sampled during RS to determine hormone levels. During the first period of RS, ACTH and corticosterone responses were diminished at d5 in CD- compared to chow-fed rats. Independently of feeding, TEL did not reduce stress hormones. Compared to food behavior before RS, the stress-induced CD eating increased in controls but remained unchanged in TEL-treated rats. After 12 weeks, TEL reduced weight gain and energy intake, particularly in CD-fed rats. Similar to the first RS period, corticosterone response was reduced in CD-fed rats at d5 during the second RS period. TEL did not further reduce stress hormones and did not lessen the CD eating upon RS. We conclude that CD feeding compensates for stress reactions. However, stress-induced CD eating was only reduced by TEL after short-term, but not after long-term drug treatment. Thus, the potency of ARBs to lower HPA activity only plays a minor role in reducing energy intake to prevent obesity.
Language	English
Publishing date	2018-10-01
Publishing country	England
Document type	Journal Article
ZDB-ID	3028-4
ISSN	1479-6805 ; 0022-0795
ISSN (online)	1479-6805
ISSN	0022-0795
DOI	10.1530/JOE-18-0477
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Article ; Online: The Arabidopsis leucine-rich repeat receptor-like kinase MIK2 is a crucial component of early immune responses to a fungal-derived elicitor.

Coleman, Alexander D / Maroschek, Julian / Raasch, Lars / Takken, Frank L W / Ranf, Stefanie / Hückelhoven, Ralph

The New phytologist

2020 Volume 229, Issue 6, Page(s) 3453–3466

Abstract: Fusarium spp. cause severe economic damage in many crops, exemplified by Panama disease of banana or Fusarium head blight of wheat. Plants sense immunogenic patterns (termed elicitors) at the cell surface to initiate pattern-triggered immunity (PTI). ... ...

Abstract	Fusarium spp. cause severe economic damage in many crops, exemplified by Panama disease of banana or Fusarium head blight of wheat. Plants sense immunogenic patterns (termed elicitors) at the cell surface to initiate pattern-triggered immunity (PTI). Knowledge of fungal elicitors and corresponding plant immune-signaling is incomplete but could yield valuable sources of resistance. We characterized Arabidopsis thaliana PTI responses to a peptide elicitor fraction present in several Fusarium spp. and employed a forward-genetic screen using plants containing a cytosolic calcium reporter to isolate fusarium elicitor reduced elicitation (fere) mutants. We mapped the causal mutation in fere1 to the leucine-rich repeat receptor-like kinase MDIS1-INTERACTING RECEPTOR-LIKE KINASE 2 (MIK2) and confirmed a crucial role of MIK2 in fungal elicitor perception. MIK2-dependent elicitor responses depend on known signaling components and transfer of AtMIK2 is sufficient to confer elicitor sensitivity to Nicotiana benthamiana. Arabidopsis senses Fusarium elicitors by a novel receptor complex at the cell surface that feeds into common PTI pathways. These data increase mechanistic understanding of PTI to Fusarium and place MIK2 at a central position in Arabidopsis elicitor responses.
MeSH term(s)	Arabidopsis ; Arabidopsis Proteins ; Immunity ; Leucine ; Plant Diseases ; Plant Immunity ; Protein Kinases ; Receptors, Cell Surface
Chemical Substances	Arabidopsis Proteins ; Receptors, Cell Surface ; Protein Kinases (EC 2.7.-) ; MIK2 protein, Arabidopsis (EC 2.7.11.1) ; Leucine (GMW67QNF9C)
Language	English
Publishing date	2020-12-30
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	208885-x
ISSN	1469-8137 ; 0028-646X
ISSN (online)	1469-8137
ISSN	0028-646X
DOI	10.1111/nph.17122
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Article: The AT1 Receptor Blocker Telmisartan Reduces Intestinal Mucus Thickness in Obese Mice.

Nickel, Laura / Sünderhauf, Annika / Rawish, Elias / Stölting, Ines / Derer, Stefanie / Thorns, Christoph / Matschl, Urte / Othman, Alaa / Sina, Christian / Raasch, Walter

Frontiers in pharmacology

2022 Volume 13, Page(s) 815353

Abstract: The angiotensin II (type 1) ( ... ...

Abstract	The angiotensin II (type 1) (AT
Language	English
Publishing date	2022-03-31
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2587355-6
ISSN	1663-9812
ISSN	1663-9812
DOI	10.3389/fphar.2022.815353
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Article: Incidence of microvascular dysfunction is increased in hyperlipidemic mice, reducing cerebral blood flow and impairing remote memory.

Hernandez Torres, Luis Daniel / Rezende, Flavia / Peschke, Eva / Will, Olga / Hövener, Jan-Bernd / Spiecker, Frauke / Özorhan, Ümit / Lampe, Josephine / Stölting, Ines / Aherrahrou, Zouhair / Künne, Carsten / Kusche-Vihrog, Kristina / Matschl, Urte / Hille, Susanne / Brandes, Ralf P / Schwaninger, Markus / Müller, Oliver J / Raasch, Walter

Frontiers in endocrinology

2024 Volume 15, Page(s) 1338458

Abstract: Introduction: The development of cognitive dysfunction is not necessarily associated with diet-induced obesity. We hypothesized that cognitive dysfunction might require additional vascular damage, for example, in atherosclerotic mice.: Methods: We ... ...

Abstract	Introduction: The development of cognitive dysfunction is not necessarily associated with diet-induced obesity. We hypothesized that cognitive dysfunction might require additional vascular damage, for example, in atherosclerotic mice. Methods: We induced atherosclerosis in male C57BL/6N mice by injecting AAV-PCSK9 Results: In AAV-PCSK9 Discussion: We conclude that the hyperlipidemic PCSK9
MeSH term(s)	Male ; Mice ; Animals ; Proprotein Convertase 9/genetics ; Incidence ; Mice, Inbred C57BL ; Hyperlipidemias/pathology ; Atherosclerosis/metabolism ; Cholesterol ; Cerebrovascular Circulation/physiology
Chemical Substances	PCSK9 protein, human (EC 3.4.21.-) ; Proprotein Convertase 9 (EC 3.4.21.-) ; Cholesterol (97C5T2UQ7J)
Language	English
Publishing date	2024-02-26
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2592084-4
ISSN	1664-2392
ISSN	1664-2392
DOI	10.3389/fendo.2024.1338458
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