LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 10

Search options

  1. Article ; Online: Lupus pernio: sarcoid-specific cutaneous manifestation associated with chronic sarcoid arthropathy.

    Efthimiou, Petros / Kukar, Manil

    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases

    2011  Volume 17, Issue 6, Page(s) 343

    MeSH term(s) Adult ; Antibodies, Monoclonal/therapeutic use ; Biopsy ; Comorbidity ; Drug Therapy, Combination ; Humans ; Infliximab ; Lupus Erythematosus, Cutaneous/diagnosis ; Lupus Erythematosus, Cutaneous/drug therapy ; Lupus Erythematosus, Cutaneous/epidemiology ; Male ; Methotrexate/therapeutic use ; Prednisone/therapeutic use ; Sarcoidosis/diagnosis ; Sarcoidosis/drug therapy ; Sarcoidosis/epidemiology ; Skin/pathology ; Treatment Outcome
    Chemical Substances Antibodies, Monoclonal ; Infliximab (B72HH48FLU) ; Prednisone (VB0R961HZT) ; Methotrexate (YL5FZ2Y5U1)
    Language English
    Publishing date 2011-09
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1283266-2
    ISSN 1536-7355 ; 1076-1608
    ISSN (online) 1536-7355
    ISSN 1076-1608
    DOI 10.1097/RHU.0b013e31822e0df0
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4815: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Complementary and alternative medicine use in rheumatoid arthritis: proposed mechanism of action and efficacy of commonly used modalities.

    Efthimiou, Petros / Kukar, Manil

    Rheumatology international

    2009  Volume 30, Issue 5, Page(s) 571–586

    Abstract: Complementary and alternative medicine (CAM) has become popular in patients with rheumatoid arthritis (RA) worldwide. The objective of this study is to systematically review the proposed mechanisms of action and currently available evidence supporting ... ...

    Abstract Complementary and alternative medicine (CAM) has become popular in patients with rheumatoid arthritis (RA) worldwide. The objective of this study is to systematically review the proposed mechanisms of action and currently available evidence supporting the efficacy of CAM modalities in relieving signs and symptoms of RA. The prevalence of CAM usage by RA patients is anywhere from 28% to 90%. Many published studies on CAM are based on animal models of RA and there is often insufficient evidence for the efficacy of CAM modalities in RA. The existing evidence suggests that some of the CAM modalities, such as acupuncture, herbal medicines, dietary omega-3 fatty acids, vitamins, and pulsed electromagnetic field show promising efficacy in reducing pain. While the use of CAM modalities for the treatment of RA continues to increase, rigorous clinical trials examining their efficacy are necessary to validate or refute the clinical claims made for CAM therapies.
    MeSH term(s) Animals ; Arthritis, Rheumatoid/therapy ; Complementary Therapies/adverse effects ; Complementary Therapies/methods ; Disease Models, Animal ; Evidence-Based Medicine ; Humans ; Treatment Outcome
    Language English
    Publishing date 2009-10-30
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 8286-7
    ISSN 1437-160X ; 0172-8172
    ISSN (online) 1437-160X
    ISSN 0172-8172
    DOI 10.1007/s00296-009-1206-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1639: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article: Images in rheumatology. Severe adult-onset calcinosis in a patient with a history of juvenile dermatomyositis.

    Efthimiou, Petros / Kukar, Manil / Kagen, Lawrence J

    The Journal of rheumatology

    2010  Volume 37, Issue 1, Page(s) 194

    MeSH term(s) Age of Onset ; Calcinosis/etiology ; Calcium/metabolism ; Child ; Dermatomyositis/complications ; Dermatomyositis/pathology ; Humans ; Male ; Middle Aged
    Chemical Substances Calcium (SY7Q814VUP)
    Language English
    Publishing date 2010-01
    Publishing country Canada
    Document type Case Reports ; Journal Article
    ZDB-ID 194928-7
    ISSN 1499-2752 ; 0315-162X
    ISSN (online) 1499-2752
    ISSN 0315-162X
    DOI 10.3899/jrheum.090628
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1168: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 135: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Clinical Image: posterior reversible encephalopathy syndrome as a severe manifestation of neuropsychiatric systemic lupus erythematosus.

    Efthimiou, Petros / Kukar, Manil / Krishnan, Preethi

    Arthritis and rheumatism

    2010  Volume 62, Issue 6, Page(s) 1692

    MeSH term(s) Adult ; Brain/pathology ; Female ; Humans ; Magnetic Resonance Imaging ; Posterior Leukoencephalopathy Syndrome/diagnosis
    Language English
    Publishing date 2010-06
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 127294-9
    ISSN 1529-0131 ; 0004-3591 ; 2326-5191
    ISSN (online) 1529-0131
    ISSN 0004-3591 ; 2326-5191
    DOI 10.1002/art.27471
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 24: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 523: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: PCP chemoprophylaxis is essential for lymphopenic dermatomyositis patients treated with immunomodulators.

    Efthimiou, Petros / Pokharna, Hiren / Kukar, Manil / Hennessey, Karen

    Muscle & nerve

    2011  Volume 43, Issue 6, Page(s) 918–919

    MeSH term(s) Chemoprevention/methods ; Chemoprevention/standards ; Dermatomyositis/drug therapy ; Dermatomyositis/etiology ; Dermatomyositis/immunology ; Humans ; Inflammation Mediators/adverse effects ; Inflammation Mediators/therapeutic use ; Lymphopenia/complications ; Lymphopenia/drug therapy ; Lymphopenia/immunology ; Male ; Middle Aged ; Opportunistic Infections/drug therapy ; Opportunistic Infections/etiology ; Opportunistic Infections/prevention & control ; Prednisone/adverse effects ; Prednisone/therapeutic use
    Chemical Substances Inflammation Mediators ; Prednisone (VB0R961HZT)
    Language English
    Publishing date 2011-06
    Publishing country United States
    Document type Case Reports ; Letter
    ZDB-ID 438353-9
    ISSN 1097-4598 ; 0148-639X
    ISSN (online) 1097-4598
    ISSN 0148-639X
    DOI 10.1002/mus.21997
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1449: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 551: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Rituximab and lupus interstitial lung disease: friend or foe?

    Efthimiou, Petros / Kukar, Manil / Hersh, Alissa

    International journal of rheumatic diseases

    2011  Volume 14, Issue 1, Page(s) e3–4

    MeSH term(s) Adult ; Antibodies, Monoclonal, Murine-Derived/therapeutic use ; Antirheumatic Agents/therapeutic use ; Drug Therapy, Combination ; Dyspnea/drug therapy ; Dyspnea/etiology ; Dyspnea/physiopathology ; Glucocorticoids/therapeutic use ; Humans ; Hydroxychloroquine/therapeutic use ; Immunologic Factors/therapeutic use ; Lung Diseases, Interstitial/drug therapy ; Lung Diseases, Interstitial/etiology ; Lung Diseases, Interstitial/physiopathology ; Lupus Erythematosus, Systemic/complications ; Lupus Erythematosus, Systemic/drug therapy ; Male ; Mycophenolic Acid/analogs & derivatives ; Mycophenolic Acid/therapeutic use ; Prednisolone/therapeutic use ; Respiratory Function Tests ; Rituximab ; Sjogren's Syndrome/complications ; Sjogren's Syndrome/drug therapy ; Treatment Outcome
    Chemical Substances Antibodies, Monoclonal, Murine-Derived ; Antirheumatic Agents ; Glucocorticoids ; Immunologic Factors ; Rituximab (4F4X42SYQ6) ; Hydroxychloroquine (4QWG6N8QKH) ; Prednisolone (9PHQ9Y1OLM) ; Mycophenolic Acid (HU9DX48N0T)
    Language English
    Publishing date 2011-02
    Publishing country England
    Document type Case Reports ; Letter
    ZDB-ID 2426924-4
    ISSN 1756-185X ; 1756-1841
    ISSN (online) 1756-185X
    ISSN 1756-1841
    DOI 10.1111/j.1756-185X.2010.01592.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6098: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Biological targets in the treatment of rheumatoid arthritis: a comprehensive review of current and in-development biological disease modifying anti-rheumatic drugs.

    Kukar, Manil / Petryna, Olga / Efthimiou, Petros

    Biologics : targets & therapy

    2009  Volume 3, Page(s) 443–457

    Abstract: Enhanced understanding of the rheumatoid arthritis (RA) pathophysiology and the role of cytokines has enabled the development of innovative biological agents in the last 10 years that target specific parts of the immune response. Failure to achieve ... ...

    Abstract Enhanced understanding of the rheumatoid arthritis (RA) pathophysiology and the role of cytokines has enabled the development of innovative biological agents in the last 10 years that target specific parts of the immune response. Failure to achieve adequate response with traditional disease modifying anti-rheumatic drugs (DMARDs) and increasing evidence of ongoing radiographic deterioration of the affected joints despite seemingly clinical response were essential stimuli for the development of biologics. The current and upcoming biological agents are primarily aimed at neutralizing circulating and cell-bound pro-inflammatory cytokines, interfering in the interaction of antigen-presenting and T-lymphocytes, eliminating circulating B-lymphocytes or by interfering with the intracellular signaling mechanisms of immuno-competent cells that lead to inflammation. These agents have improved the currently available treatments due to greater efficacy, fast action and greater tolerability. However, use of these agents has also been associated with significant, although rare, adverse events and considerable cost. Therefore, these agents should be used with caution by experienced clinicians. The present work aims to provide a global and updated review of the current and in-development biological DMARDs for the treatment of RA.
    Language English
    Publishing date 2009-10-12
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2415708-9
    ISSN 1177-5491 ; 1177-5475
    ISSN (online) 1177-5491
    ISSN 1177-5475
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Complementary and alternative medicine in rheumatoid arthritis: no longer the last resort!

    Efthimiou, Petros / Kukar, Manil / Mackenzie, C Ronald

    HSS journal : the musculoskeletal journal of Hospital for Special Surgery

    2009  Volume 6, Issue 1, Page(s) 108–111

    Abstract: Complementary and alternative medicine (CAM) has become popular with consumers worldwide and accounts for significant private and public health expenditures. According to earlier reports, the prevalence of CAM use by rheumatoid arthritis (RA) patients in ...

    Abstract Complementary and alternative medicine (CAM) has become popular with consumers worldwide and accounts for significant private and public health expenditures. According to earlier reports, the prevalence of CAM use by rheumatoid arthritis (RA) patients in the United States is anywhere between 28% and 90%. Extensive use among RA patients and the limited knowledge among physicians had confirmed the need to evaluate the increasing prevalence of various CAM modalities. The primary aim of this study was to identify the incidence of CAM usage among our RA patients. Additionally, we aimed to correlate patient demographics and disease characteristics with the use of specific CAM modalities. An analysis of data extracted from our institution's RA longitudinal registry was performed. The patients were asked to select from a list the modalities they were currently using and/or had used in the past. Of patients, 75.9% reported current or past use of CAM with >10% using 12 different modalities. Nutritional supplements and touch therapies were the most widely used overall, with mind-body therapies more prevalent among younger patients. CAM users were found to have more extra-articular manifestations and fewer comorbidities than non-CAM users. The use of CAM among RA patients is widespread with a broad spectrum of CAM modalities being used in early stages of the disease, frequently in conjunction with mainstream conventional treatments. Therefore, CAM may no longer be considered the rheumatoid patients' last resort.
    Language English
    Publishing date 2009-09-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2250601-9
    ISSN 1556-3324 ; 1556-3316
    ISSN (online) 1556-3324
    ISSN 1556-3316
    DOI 10.1007/s11420-009-9133-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6398: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Biological targets in the treatment of rheumatoid arthritis

    Manil Kukar / Olga Petryna / Petros Efthimiou

    Biologics: Targets & Therapy, Vol 2009, Iss default, Pp 443-

    a comprehensive review of current and in-development biological disease modifying anti-rheumatic drugs

    2009  Volume 457

    Abstract: Manil Kukar1, Olga Petryna1, Petros Efthimiou21Rheumatology Division, Lincoln Medical and ...

    Abstract Manil Kukar1, Olga Petryna1, Petros Efthimiou21Rheumatology Division, Lincoln Medical and Mental Health Center, New York, NY, USA; 2Lincoln Medical and Mental Health Center, Weill Cornell Medical College, New York, NY, USAAbstract: Enhanced understanding of the rheumatoid arthritis (RA) pathophysiology and the role of cytokines has enabled the development of innovative biological agents in the last 10 years that target specific parts of the immune response. Failure to achieve adequate response with traditional disease modifying anti-rheumatic drugs (DMARDs) and increasing evidence of ongoing radiographic deterioration of the affected joints despite seemingly clinical response were essential stimuli for the development of biologics. The current and upcoming biological agents are primarily aimed at neutralizing circulating and cell-bound pro-inflammatory cytokines, interfering in the interaction of antigen-presenting and T-lymphocytes, eliminating circulating B-lymphocytes or by interfering with the intracellular signaling mechanisms of immuno-competent cells that lead to inflammation. These agents have improved the currently available treatments due to greater efficacy, fast action and greater tolerability. However, use of these agents has also been associated with significant, although rare, adverse events and considerable cost. Therefore, these agents should be used with caution by experienced clinicians. The present work aims to provide a global and updated review of the current and in-development biological DMARDs for the treatment of RA.Keywords: biological agents, rheumatoid arthritis, immunomodulators, treatment, cytokines
    Keywords Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2009-09-01T00:00:00Z
    Publisher Dove Medical Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  10. Article ; Online: Complex Situations in Patients with Adult-Onset Still’s Disease

    Efthimiou, Petros V. / Kukar, Manil / Petryna, Olga

    Autoimmune Diseases

    Abstract: Adult-onset Still’s disease (AOSD) is a rare systemic inflammatory disorder of unknown etiology, characterized by quotidian or double quotidian fever, a peri-febrile cutaneous eruption, polyarthritis, and multiorgan involvement. AOSD is a challenging ... ...

    Abstract Adult-onset Still’s disease (AOSD) is a rare systemic inflammatory disorder of unknown etiology, characterized by quotidian or double quotidian fever, a peri-febrile cutaneous eruption, polyarthritis, and multiorgan involvement. AOSD is a challenging disease with protean disease manifestations and rare, albeit potentially life-threatening, complications. In such cases, prompt diagnosis and treatment may prove life-saving. The purpose of this chapter is to review the diagnosis and management of challenging clinical situations in AOSD patients that are associated with significant morbidity and mortality and to provide the readers with information that could aid their decision-making process.
    Keywords covid19
    Publisher PMC
    Document type Article ; Online
    DOI 10.1007/978-0-85729-358-9_14
    Database COVID19

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top