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  1. Book ; Online: Geometric interpretation of the general POE model for a serial-link robot via conversion into D-H parameterization

    Wu, Liao / Crawford, Ross / Roberts, Jonathan

    2019  

    Abstract: ... the kinematics of a serial-link robot, the Denavit-Hartenberg (D-H) notation is still the most widely used due ... to automatically convert a POE model into a D-H model for a robot with revolute, prismatic, and helical joints ... where it is necessary to convert the D-H model to the POE model for identification and then back to the D-H ...

    Abstract While Product of Exponentials (POE) formula has been gaining increasing popularity in modeling the kinematics of a serial-link robot, the Denavit-Hartenberg (D-H) notation is still the most widely used due to its intuitive and concise geometric interpretation of the robot. This paper has developed an analytical solution to automatically convert a POE model into a D-H model for a robot with revolute, prismatic, and helical joints, which are the complete set of three basic one degree of freedom lower pair joints for constructing a serial-link robot. The conversion algorithm developed can be used in applications such as calibration where it is necessary to convert the D-H model to the POE model for identification and then back to the D-H model for compensation. The equivalence of the two models proved in this paper also benefits the analysis of the identifiability of the kinematic parameters. It is found that the maximum number of identifiable parameters in a general POE model is 5h+4r +2t +n+6 where h, r, t, and n stand for the number of helical, revolute, prismatic, and general joints, respectively. It is also suggested that the identifiability of the base frame and the tool frame in the D-H model is restricted rather than the arbitrary six parameters as assumed previously.

    Comment: Product of Exponentials (POE), Denavit-Hartenberg (D-H), kinematics, identifiability, ICRA2019
    Keywords Computer Science - Robotics
    Subject code 629
    Publishing date 2019-02-01
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article: Comparison of [(3)H]-(2S,4R)-4-methylglutamate and [(3)H]D-aspartate as ligands for binding and autoradiographic analyses of glutamate transporters.

    Apricò, K / Beart, P M / Crawford, D / O'shea, R D

    Neurochemistry international

    2007  Volume 51, Issue 8, Page(s) 507–516

    Abstract: While studies with [(3)H]D-aspartate ([(3)H]d-Asp) illustrate specific interactions ... Pharmacological studies revealed that [(3)H]4MG, unlike [(3)H]d-Asp, labeled both EAAT and ionotropic GluR sites ... and [(3)H]d-Asp revealed wide, but discrete distributions in forebrain; significant differences ...

    Abstract While studies with [(3)H]D-aspartate ([(3)H]d-Asp) illustrate specific interactions with excitatory amino acid transporters (EAATs), new insights into the pharmacological characteristics and localization of specific EAAT subtypes depend upon the availability of novel ligands. One such ligand is [(3)H]-(2S,4R)-4-methylglutamate ([(3)H]4MG) which labels astrocytic EAATs in homogenate binding studies. This study examined the utility of [(3)H]4MG for binding and autoradiography in coronal sections of rat brain. Binding of [(3)H]4MG was optimal in 5mM HEPES buffer containing 96 mM NaCl, pH 7.5. Specific binding of [(3)H]4MG exhibited two components, but was to a single site when glutamate receptor (GluR) sites were masked with kainate (KA; 1 microM): t(1/2) approximately 5 min, K(d) 250 nM and B(max) 5.4 pmol/mg protein. Pharmacological studies revealed that [(3)H]4MG, unlike [(3)H]d-Asp, labeled both EAAT and ionotropic GluR sites. Further studies employed 6-cyano-7-nitroquinoxaline (30 microM) to block GluR sites, but selective EAAT ligands displayed lower potency than expected for binding to transporters relative to drugs possessing mixed transporter/receptor activities. Autoradiography in conjunction with densitometry with [(3)H]4MG and [(3)H]d-Asp revealed wide, but discrete distributions in forebrain; significant differences in binding levels were found in hippocampus, nucleus accumbens and cortical sub-areas. Although EAAT1 and EAAT2 components were detectable using 3-methylglutamate and serine-O-sulphate, respectively, the majority of [(3)H]4MG binding was to KA-related sites. Overall, in tissue sections [(3)H]4MG proved unsuitable for studying the autoradiographic localization of EAATs apparently due to its inability to selectively discriminate Na(+)-dependent binding to Glu transporters.
    MeSH term(s) Animals ; Autoradiography/methods ; Binding, Competitive/drug effects ; Binding, Competitive/physiology ; D-Aspartic Acid/metabolism ; Excitatory Amino Acid Agonists/pharmacology ; Excitatory Amino Acid Antagonists/pharmacology ; Excitatory Amino Acid Transporter 1/drug effects ; Excitatory Amino Acid Transporter 1/metabolism ; Excitatory Amino Acid Transporter 2/drug effects ; Excitatory Amino Acid Transporter 2/metabolism ; Female ; Glutamates/metabolism ; Glutamic Acid/metabolism ; Ligands ; Radioligand Assay/methods ; Rats ; Rats, Sprague-Dawley ; Receptors, Glutamate/drug effects ; Receptors, Glutamate/metabolism ; Tritium/metabolism
    Chemical Substances Excitatory Amino Acid Agonists ; Excitatory Amino Acid Antagonists ; Excitatory Amino Acid Transporter 1 ; Excitatory Amino Acid Transporter 2 ; Glutamates ; Ligands ; Receptors, Glutamate ; Slc1a2 protein, rat ; Slc1a3 protein, rat ; Tritium (10028-17-8) ; 4-methylglutamic acid (14561-55-8) ; Glutamic Acid (3KX376GY7L) ; D-Aspartic Acid (4SR0Q8YD1X)
    Language English
    Publishing date 2007-12
    Publishing country England
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 283190-9
    ISSN 1872-9754 ; 0197-0186
    ISSN (online) 1872-9754
    ISSN 0197-0186
    DOI 10.1016/j.neuint.2007.05.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: Henrik Blum, M.D., M.P.H

    Blum, Henrik L / Crawford, Caroline

    equity for the public's health : Contra Costa health officer : professor, UC School of Public Health : WHO fieldworker

    (University history series)

    1999  

    Title variant Equity for the public's health
    Institution Bancroft Library. / Regional Oral History Office
    Author's details interviews conducted by Caroline Crawford in 1997 ; introduction by William C. Reeves
    Series title University history series
    MeSH term(s) Public Health
    Language English
    Size xiii, 425 p. :, ports.
    Publisher Regional Oral History Office, Bancroft Library, University of California
    Publishing place Berkeley, Calif
    Document type Book
    Database Catalogue of the US National Library of Medicine (NLM)

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  4. Article: Preliminary comparisons between a point-of-care ketometer and reference method using Steller sea lion pup whole blood and plasma.

    Crawford, Stephanie G / Coker, Robert H / Rea, Lorrie D

    Conservation physiology

    2024  Volume 12, Issue 1, Page(s) coad104

    Abstract: We evaluated the Precision Xtra™ ketometer as part of a larger study categorizing fasting status of free-ranging Steller sea lion ( ...

    Abstract We evaluated the Precision Xtra™ ketometer as part of a larger study categorizing fasting status of free-ranging Steller sea lion (
    Language English
    Publishing date 2024-01-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 2721508-8
    ISSN 2051-1434
    ISSN 2051-1434
    DOI 10.1093/conphys/coad104
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Elbow Ulnar Collateral Ligament (UCL) Repair Using Suture Augmentation, Anchors, and Bone Tunnels.

    Crawford, Benjamin D / Alrabaa, Rami George / Akizuki, Kenneth H

    Arthroscopy techniques

    2023  Volume 12, Issue 10, Page(s) e1715–e1719

    Abstract: Ulnar collateral ligament (UCL) repair with suture augmentation has been increasingly used to treat UCL pathology in overhead athletes. For the appropriately indicated patient, UCL repair with suture augmentation without reconstruction has promising ... ...

    Abstract Ulnar collateral ligament (UCL) repair with suture augmentation has been increasingly used to treat UCL pathology in overhead athletes. For the appropriately indicated patient, UCL repair with suture augmentation without reconstruction has promising results. Advantages of repair with suture augmentation include earlier return to sport, low complication rate, and decreased operative time since there is no need for graft harvest. Previously reported techniques use suture anchors with high-tensile and collagen-coated nonabsorbable sutures. This article provides an alternative augmentation method using a combination of anchors and bone tunnels to obtain an isometric repair.
    Language English
    Publishing date 2023-09-11
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2653101-X
    ISSN 2212-6287
    ISSN 2212-6287
    DOI 10.1016/j.eats.2023.05.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Using the capability, opportunity, and motivation model of behaviour to assess provider perception of implementing solution-focused goal-setting in paediatric rehabilitation.

    Crawford, L / Colquhoun, H / Kingsnorth, S / Fehlings, D / Fayed, Nora

    Journal of child health care : for professionals working with children in the hospital and community

    2023  , Page(s) 13674935231194501

    Abstract: Adoption of family and child goal-setting in paediatric rehabilitation is important to positive long-term outcomes. Solution-focused coaching (SFC) has been identified as a promising approach to ensuring this type of goal-setting occurs, while the actual ...

    Abstract Adoption of family and child goal-setting in paediatric rehabilitation is important to positive long-term outcomes. Solution-focused coaching (SFC) has been identified as a promising approach to ensuring this type of goal-setting occurs, while the actual implementation of SFC by health care providers (HCPs) is low. This study utilized the capacity, opportunity, and motivation model of behaviour change (COM-B) to identify which strengths and difficulties health care providers (HCPs) perceived with respect to SFC goal-setting in paediatric rehabilitation. A self-report survey was developed and administered to HCPs at a paediatric rehabilitation hospital. Each survey question was based upon a COM-B sub-component. Demographic information was collected from HCPs, and descriptive statistics were used to rank perceived COM-B components from strongest to weakest. Results indicate HCPs view the provision of SFC goal-setting as an important practice, while they also perceive difficulties to actual delivery due to: lack of adequate individual skill, lack of experience with this type of goal-setting, and insufficient preparation for clients to engage in sharing their goals. HCPs also perceived lack of organizational processes to support the practice within their teams. Recommendations for intervention are provided.
    Language English
    Publishing date 2023-08-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2299167-0
    ISSN 1741-2889 ; 1367-4935
    ISSN (online) 1741-2889
    ISSN 1367-4935
    DOI 10.1177/13674935231194501
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Married women's response to spousal pornography use: A grounded theory.

    Crawford, Misha D / Butler, Mark H / Marks, Loren D / Leavitt, Chelom J

    Journal of marital and family therapy

    2023  Volume 50, Issue 1, Page(s) 95–119

    Abstract: Empirical research suggests that married women may more commonly experience spousal pornography use as a relational attachment threat and are more likely to experience negative relational outcomes such as distress and loss of trust. The purpose of this ... ...

    Abstract Empirical research suggests that married women may more commonly experience spousal pornography use as a relational attachment threat and are more likely to experience negative relational outcomes such as distress and loss of trust. The purpose of this study was to develop a grounded theory of married women's response to the discovery or disclosure of spousal pornography use. This study included the experiences of 30 married women who reported spousal pornography use as a threat to relational attachment, who chose to remain with their spouse, and who reported evidence of individual and relational healing thereafter. The research question, "How do married women describe the experience of learning of their spouse's pornography use and the individual and relationship sequelae that follow?" was explored using grounded theory methods to analyze deidentified blogpost accounts emphasizing response to a spouse's pornography use. The results describe a process model highlighting three interrelated informant categories-emotional response, mental response, and physical response-and one resultant category-behavioral response. Implications include (a) the importance of open communication regarding pornography use within relationships, (b) the necessity for individual and relational healing following betrayal trauma, and (c) the role of therapeutic intervention in shaping adaptive healing processes.
    MeSH term(s) Humans ; Female ; Erotica/psychology ; Grounded Theory ; Marriage/psychology ; Spouses/psychology ; Emotions
    Language English
    Publishing date 2023-10-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 224679-x
    ISSN 1752-0606 ; 0194-472X
    ISSN (online) 1752-0606
    ISSN 0194-472X
    DOI 10.1111/jmft.12672
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: The effect of myelography dye on bone density measurements utilizing Hounsfield units on CT.

    Weegens, Ryan / Crawford, Charles H / Glassman, Steven D / Dimar, John R / Gum, Jeffrey L / Carreon, Leah Y

    Journal of neurosurgery. Spine

    2024  Volume 40, Issue 4, Page(s) 513–518

    Abstract: Objective: Hounsfield unit (HU) measurements of bone density on CT are increasingly used for preoperative planning in spine surgery. Postmyelogram CT is another common preoperative diagnostic study. However, there is no current literature evaluating ... ...

    Abstract Objective: Hounsfield unit (HU) measurements of bone density on CT are increasingly used for preoperative planning in spine surgery. Postmyelogram CT is another common preoperative diagnostic study. However, there is no current literature evaluating whether HU measurements on CT are affected by the presence of myelography dye. The purpose of the current study was to determine if the presence of myelography dye affects HU measurements of bone density in CT studies.
    Methods: Twenty-nine preoperative spine surgery patients who underwent both standard and postmyelography CT performed within 6 months of each other were identified. HU measurements were obtained from an elliptical region of interest using the available software on a standard PACS. Measurements were obtained on the axial cut at the midvertebral body on all lumbar vertebrae on three separate occasions and an average value was calculated for comparative analysis. A 6-week gap was used between measurements of the CT scans and the CT myelograms to diminish bias.
    Results: The mean age of the cohort was 69 years and the average BMI was 32 kg/m2. Five patients were male and 24 were female. Six of the patients had instrumentation placed prior to the initial CT scan. The average HU measurements for CT levels L1-5 were 165, 171, 145, 154, and 225, respectively, whereas HU measurements for CT myelography of levels L1-5 were 168, 177, 148, 170, and 239, respectively. Strong correlations were noted between the HU measured on CT and CT myelography for L1 (r2 = 0.951), L2 (r2 = 0.966), L4 (r2 = 0.820), and L5 (r2 = 0.900), and moderate for L3 (r2 = 0.668).
    Conclusions: The presence of myelography dye had no clear effect on CT HU measurements of bone density. The results of this study support the use of CT myelograms for bone density assessment in the absence of standard CT images.
    MeSH term(s) Humans ; Male ; Female ; Aged ; Bone Density ; Osteoporosis ; Absorptiometry, Photon/methods ; Tomography, X-Ray Computed/methods ; Lumbar Vertebrae/diagnostic imaging ; Myelography ; Retrospective Studies
    Language English
    Publishing date 2024-01-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2158643-3
    ISSN 1547-5646 ; 1547-5654
    ISSN (online) 1547-5646
    ISSN 1547-5654
    DOI 10.3171/2023.11.SPINE23890
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Early Experience With an Endocrinology Preoperative Fast-Track Program for Optimizing Spine Surgery Candidates With Poorly Controlled Diabetes Mellitus.

    Crawford, Charles H / Glassman, Steven D / Gum, Jeffrey L / Barriger, Megan L / Carreon, Leah Y

    The Journal of the American Academy of Orthopaedic Surgeons

    2023  Volume 31, Issue 9, Page(s) 458–462

    Abstract: Introduction: Previous studies demonstrated an increase in adverse outcomes for patients undergoing elective surgeries with poorly controlled diabetes mellitus. At a large, tertiary-care spine center with a notable population of patients with poorly ... ...

    Abstract Introduction: Previous studies demonstrated an increase in adverse outcomes for patients undergoing elective surgeries with poorly controlled diabetes mellitus. At a large, tertiary-care spine center with a notable population of patients with poorly controlled diabetes, an Endocrinology Fast-Track (EFT) program was developed to improve patient optimization before elective spine surgery. The purpose of this study was to report our early experience.
    Methods: Seventy-five patients who were scheduled for elective spine surgery were noted to have Hgb A1c > 7 on preoperative evaluation. Thirty-two patients accepted referral to the EFT program and 43 declined (non-EFT). Mean preoperative Hgb A1c was similar between groups (EFT: 8.79 versus non-EFT: 9.26, P = 0.221). The Fast-Track program included counseling, education, and medical management.
    Results: Patients in the two groups were similar in number of females (EFT: 17 versus non-EFT: 17, P = 0.348), age (EFT: 57.7 versus non-EFT: 60.6, P = 0.280), and body mass index (EFT: 34.6 versus non-EFT: 33.0, P = 0.341). A smaller number of smokers were there in the EFT group (1) compared with the non-EFT group (15, P = 0.003). The proportion of patients on insulin (EFT: 19 versus non-EFT: 23, P = 0.814) and oral hypoglycemics (EFT: 29 versus non-EFT: 39, P = 0.983) was similar between the two groups. Surgical clearance for patients with a documented preoperative Hgb A1c of < 7 or equivalent fructosamine level was significantly better in the Fast-Track group compared with the non-Fast-Track group (91% versus 42%, P = 0.000). Although most patients who declined the Fast-Track program did not obtain clearance for surgery, mean Hgb A1c was improved at the latest follow-up in both groups for those who obtained surgical clearance (7.10 versus 6.78, P = 0.470).
    Discussion: A novel EFT program was successful in obtaining acceptable blood glucose control in patients recommended for spine surgery who had poorly controlled diabetes mellitus on preoperative evaluation. The improved blood glucose control was maintained at the latest follow-up.
    MeSH term(s) Female ; Humans ; Glycated Hemoglobin ; Diabetes Mellitus ; Body Mass Index ; Referral and Consultation
    Chemical Substances Glycated Hemoglobin
    Language English
    Publishing date 2023-02-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1200524-1
    ISSN 1940-5480 ; 1067-151X
    ISSN (online) 1940-5480
    ISSN 1067-151X
    DOI 10.5435/JAAOS-D-22-00653
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Analyzing an immunization resource website: User browsing trends.

    Cheng, Daryl R / Reimer, Heinrich / Le, David / Crawford, Nigel W

    Vaccine

    2023  Volume 41, Issue 50, Page(s) 7498–7502

    Abstract: Purpose: Access to internet-based resources may help to improve population health awareness and literacy surrounding immunization related topics. The primary aim of this study was to evaluate and analyze trends for a single immunization resource website, ...

    Abstract Purpose: Access to internet-based resources may help to improve population health awareness and literacy surrounding immunization related topics. The primary aim of this study was to evaluate and analyze trends for a single immunization resource website, the Melbourne Vaccine Education Centre (MVEC).
    Principal results: Over a four-year period from 2019 to 2022, the website had over 2 million visitors from 236 countries. Users were predominantly female, in the 25 to 44 year age bracket and accessed resources using a mobile device. There was significant interest in specific vaccine related topics, particularly during the COVID-19 pandemic, that corresponded with key vaccine related recommendations and updates from a national level. Usage patterns saw spikes in interest around topics including COVID-19 vaccine administration techniques and adverse events following immunization.
    Major conclusions: Use of online platforms including websites such as MVEC may reflect trends and behaviors towards immunization related information. Analysis of usage patterns have provided user insights into key domains of interest including areas such as vaccine administration, policies and programs, vaccine safety and barriers to vaccine uptake.
    MeSH term(s) Humans ; Female ; Male ; COVID-19 Vaccines ; Pandemics/prevention & control ; Vaccination ; COVID-19/prevention & control ; Health Education ; Immunization
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2023-11-15
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 605674-x
    ISSN 1873-2518 ; 0264-410X
    ISSN (online) 1873-2518
    ISSN 0264-410X
    DOI 10.1016/j.vaccine.2023.11.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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